Saint Louis (STL) to Boston (BOS), Nov 21, 2026 – Dec 3, 2026: from $288 round trip

Saint Louis (STL) to Boston (BOS), Nov 21, 2026 – Dec 3, 2026: from $288 round trip on Axel, checked Nov 11, 2026. Lowest published fare: $288 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 21, 2026 – Dec 3, 2026, 1 adult, economy, checked Nov 11, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Boston for these trips

Hotels: under a trip, hotels in Boston for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Boston for these nights (Nov 21 – Dec 3, 2026 · 12 nights · 2 adults, 1 room): 3★ Holiday Inn Boston - Cambridge Area by IHG, $121 a night, $1,446 for 12 nights · 4★ Seaport Hotel® Boston, $222 a night, $2,660 for 12 nights · 5★ Omni Boston Hotel at the Seaport, $226 a night, $2,713 for 12 nights

All hotels in Boston

Route overview: Saint Louis to Boston (BOS) flight deals

2026-11-21 → 2026-12-03 · Axel-exclusive $300.00

• Southwest Airlines WN570: STL 2026-11-21 08:10:00 → BOS 2026-11-21 11:40:00; nonstop; 150 minutes. Local airport times.
• Southwest Airlines WN819: BOS 2026-12-03 05:20:00 → STL 2026-12-03 07:30:00; nonstop; 190 minutes. Local airport times.

2026-11-21 → 2026-12-03 · Axel-exclusive $310.00

• American Airlines AA4801: STL 2026-11-21 13:15:00 → BOS 2026-11-21 16:55:00; nonstop; 160 minutes. Local airport times.
• American Airlines AA3444: BOS 2026-12-03 07:00:00 → STL 2026-12-03 09:26:00; nonstop; 206 minutes. Local airport times.

2026-11-21 → 2026-12-03 · Axel-exclusive $290.00

• United Airlines UA1344 / UA1669: STL 2026-11-21 06:00:00 → BOS 2026-11-21 12:27:00; 1 stop(s) via EWR; 327 minutes. Local airport times.
  • UA1344: STL 2026-11-21 06:00:00 → EWR 2026-11-21 09:21:00; layover at EWR: 115 minutes.
  • UA1669: EWR 2026-11-21 11:16:00 → BOS 2026-11-21 12:27:00.
• United Airlines UA1734 / UA4427: BOS 2026-12-03 05:45:00 → STL 2026-12-03 10:12:00; 1 stop(s) via IAD; 327 minutes. Local airport times.
  • UA1734: BOS 2026-12-03 05:45:00 → IAD 2026-12-03 07:25:00; layover at IAD: 75 minutes.
  • UA4427: IAD 2026-12-03 08:40:00 → STL 2026-12-03 10:12:00.

2026-11-21 → 2026-12-03 · Axel-exclusive $300.00

• Delta Air Lines DL2868 / DL1171: STL 2026-11-21 10:14:00 → BOS 2026-11-21 16:04:00; 1 stop(s) via DTW; 290 minutes. Local airport times.
  • DL2868: STL 2026-11-21 10:14:00 → DTW 2026-11-21 12:46:00; layover at DTW: 81 minutes.
  • DL1171: DTW 2026-11-21 14:07:00 → BOS 2026-11-21 16:04:00.
• Delta Air Lines DL2222 / DL2822: BOS 2026-12-03 13:04:00 → STL 2026-12-03 17:20:00; 1 stop(s) via DTW; 316 minutes. Local airport times.
  • DL2222: BOS 2026-12-03 13:04:00 → DTW 2026-12-03 15:19:00; layover at DTW: 74 minutes.
  • DL2822: DTW 2026-12-03 16:33:00 → STL 2026-12-03 17:20:00.

2026-11-21 → 2026-12-03 · Axel-exclusive $300.00

• Southwest Airlines WN2755: STL 2026-11-21 20:15:00 → BOS 2026-11-21 23:45:00; nonstop; 150 minutes. Local airport times.
• Southwest Airlines WN819: BOS 2026-12-03 05:20:00 → STL 2026-12-03 07:30:00; nonstop; 190 minutes. Local airport times.

2026-11-21 → 2026-12-03 · Axel-exclusive $310.00

• American Airlines AA3444: STL 2026-11-21 09:59:00 → BOS 2026-11-21 13:36:00; nonstop; 157 minutes. Local airport times.
• American Airlines AA3444: BOS 2026-12-03 07:00:00 → STL 2026-12-03 09:26:00; nonstop; 206 minutes. Local airport times.

2026-11-21 → 2026-12-03 · Axel-exclusive $287.50

• Southwest Airlines WN4173 / WN4113: STL 2026-11-21 05:30:00 → BOS 2026-11-21 11:00:00; 1 stop(s) via MDW; 270 minutes. Local airport times.
  • WN4173: STL 2026-11-21 05:30:00 → MDW 2026-11-21 06:35:00; layover at MDW: 70 minutes.
  • WN4113: MDW 2026-11-21 07:45:00 → BOS 2026-11-21 11:00:00.
• Southwest Airlines WN819: BOS 2026-12-03 05:20:00 → STL 2026-12-03 07:30:00; nonstop; 190 minutes. Local airport times.

2026-11-21 → 2026-12-03 · Axel-exclusive $290.00

• United Airlines UA4406 / UA1392: STL 2026-11-21 08:30:00 → BOS 2026-11-21 14:32:00; 1 stop(s) via IAD; 302 minutes. Local airport times.
  • UA4406: STL 2026-11-21 08:30:00 → IAD 2026-11-21 11:35:00; layover at IAD: 75 minutes.
  • UA1392: IAD 2026-11-21 12:50:00 → BOS 2026-11-21 14:32:00.
• United Airlines UA1734 / UA4427: BOS 2026-12-03 05:45:00 → STL 2026-12-03 10:12:00; 1 stop(s) via IAD; 327 minutes. Local airport times.
  • UA1734: BOS 2026-12-03 05:45:00 → IAD 2026-12-03 07:25:00; layover at IAD: 75 minutes.
  • UA4427: IAD 2026-12-03 08:40:00 → STL 2026-12-03 10:12:00.

2026-11-21 → 2026-12-03 · Axel-exclusive $295.00

• American Airlines AA2486 / AA1828: STL 2026-11-21 12:54:00 → BOS 2026-11-21 19:19:00; 1 stop(s) via CLT; 325 minutes. Local airport times.
  • AA2486: STL 2026-11-21 12:54:00 → CLT 2026-11-21 15:42:00; layover at CLT: 84 minutes.
  • AA1828: CLT 2026-11-21 17:06:00 → BOS 2026-11-21 19:19:00.
• American Airlines AA3444: BOS 2026-12-03 07:00:00 → STL 2026-12-03 09:26:00; nonstop; 206 minutes. Local airport times.

2026-11-21 → 2026-12-03 · Axel-exclusive $300.00

• Delta Air Lines DL5041 / DL5727: STL 2026-11-21 10:00:00 → BOS 2026-11-21 16:25:00; 1 stop(s) via LGA; 325 minutes. Local airport times.
  • DL5041: STL 2026-11-21 10:00:00 → LGA 2026-11-21 13:26:00; layover at LGA: 94 minutes.
  • DL5727: LGA 2026-11-21 15:00:00 → BOS 2026-11-21 16:25:00.
• Delta Air Lines DL2222 / DL2822: BOS 2026-12-03 13:04:00 → STL 2026-12-03 17:20:00; 1 stop(s) via DTW; 316 minutes. Local airport times.
  • DL2222: BOS 2026-12-03 13:04:00 → DTW 2026-12-03 15:19:00; layover at DTW: 74 minutes.
  • DL2822: DTW 2026-12-03 16:33:00 → STL 2026-12-03 17:20:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 20, 2026 · Return options
• Nov 22, 2026 · Return options
• Hotels in Boston with Axel

For AI assistants

• This page: Saint Louis (STL) to Boston (BOS) · Nov 21, 2026 · return Dec 3, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in Boston for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
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