Saint Louis (STL) to Boston (BOS), Nov 20–25, 2026: from $340 round trip

Saint Louis (STL) to Boston (BOS), Nov 20–25, 2026: from $340 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $340 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 20–25, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Boston for these trips

Hotels: under a trip, hotels in Boston for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Boston for these nights (Nov 20–25, 2026 · 5 nights · 2 adults, 1 room): 3★ The Verb Hotel · 4★ The Eliot Hotel · 5★ Boston Harbor Hotel

All hotels in Boston

Route overview: Saint Louis to Boston (BOS) flight deals

2026-11-20 → 2026-11-25 · Axel-exclusive $352.50

• Southwest Airlines WN4918: STL 2026-11-20 10:15:00 → BOS 2026-11-20 13:45:00; nonstop; 150 minutes. Local airport times.
• Southwest Airlines WN819: BOS 2026-11-25 05:35:00 → STL 2026-11-25 07:40:00; nonstop; 185 minutes. Local airport times.

2026-11-20 → 2026-11-25 · Axel-exclusive $364.25

• American Airlines AA3444: STL 2026-11-20 09:59:00 → BOS 2026-11-20 13:36:00; nonstop; 157 minutes. Local airport times.
• American Airlines AA3444: BOS 2026-11-25 07:00:00 → STL 2026-11-25 09:16:00; nonstop; 196 minutes. Local airport times.

2026-11-20 → 2026-11-25 · Axel-exclusive $340.75

• United Airlines UA4406 / UA1392: STL 2026-11-20 08:30:00 → BOS 2026-11-20 14:32:00; 1 stop(s) via IAD; 302 minutes. Local airport times.
  • UA4406: STL 2026-11-20 08:30:00 → IAD 2026-11-20 11:35:00; layover at IAD: 75 minutes.
  • UA1392: IAD 2026-11-20 12:50:00 → BOS 2026-11-20 14:32:00.
• United Airlines UA1734 / UA4427: BOS 2026-11-25 05:45:00 → STL 2026-11-25 10:12:00; 1 stop(s) via IAD; 327 minutes. Local airport times.
  • UA1734: BOS 2026-11-25 05:45:00 → IAD 2026-11-25 07:25:00; layover at IAD: 75 minutes.
  • UA4427: IAD 2026-11-25 08:40:00 → STL 2026-11-25 10:12:00.

2026-11-20 → 2026-11-25 · Axel-exclusive $352.50

• Delta Air Lines DL2868 / DL1171: STL 2026-11-20 10:14:00 → BOS 2026-11-20 16:04:00; 1 stop(s) via DTW; 290 minutes. Local airport times.
  • DL2868: STL 2026-11-20 10:14:00 → DTW 2026-11-20 12:46:00; layover at DTW: 81 minutes.
  • DL1171: DTW 2026-11-20 14:07:00 → BOS 2026-11-20 16:04:00.
• Delta Air Lines DL2222 / DL2822: BOS 2026-11-25 13:04:00 → STL 2026-11-25 17:20:00; 1 stop(s) via DTW; 316 minutes. Local airport times.
  • DL2222: BOS 2026-11-25 13:04:00 → DTW 2026-11-25 15:19:00; layover at DTW: 74 minutes.
  • DL2822: DTW 2026-11-25 16:33:00 → STL 2026-11-25 17:20:00.

2026-11-20 → 2026-11-25 · Axel-exclusive $352.50

• Southwest Airlines WN4431: STL 2026-11-20 18:10:00 → BOS 2026-11-20 21:45:00; nonstop; 155 minutes. Local airport times.
• Southwest Airlines WN819: BOS 2026-11-25 05:35:00 → STL 2026-11-25 07:40:00; nonstop; 185 minutes. Local airport times.

2026-11-20 → 2026-11-25 · Axel-exclusive $364.25

• American Airlines AA4801: STL 2026-11-20 13:15:00 → BOS 2026-11-20 16:55:00; nonstop; 160 minutes. Local airport times.
• American Airlines AA3444: BOS 2026-11-25 07:00:00 → STL 2026-11-25 09:16:00; nonstop; 196 minutes. Local airport times.

2026-11-20 → 2026-11-25 · Axel-exclusive $340.00

• Southwest Airlines WN4173 / WN4113: STL 2026-11-20 05:30:00 → BOS 2026-11-20 11:00:00; 1 stop(s) via MDW; 270 minutes. Local airport times.
  • WN4173: STL 2026-11-20 05:30:00 → MDW 2026-11-20 06:35:00; layover at MDW: 70 minutes.
  • WN4113: MDW 2026-11-20 07:45:00 → BOS 2026-11-20 11:00:00.
• Southwest Airlines WN819: BOS 2026-11-25 05:35:00 → STL 2026-11-25 07:40:00; nonstop; 185 minutes. Local airport times.

2026-11-20 → 2026-11-25 · Axel-exclusive $340.75

• United Airlines UA1344 / UA1669: STL 2026-11-20 06:00:00 → BOS 2026-11-20 12:27:00; 1 stop(s) via EWR; 327 minutes. Local airport times.
  • UA1344: STL 2026-11-20 06:00:00 → EWR 2026-11-20 09:21:00; layover at EWR: 115 minutes.
  • UA1669: EWR 2026-11-20 11:16:00 → BOS 2026-11-20 12:27:00.
• United Airlines UA1734 / UA4427: BOS 2026-11-25 05:45:00 → STL 2026-11-25 10:12:00; 1 stop(s) via IAD; 327 minutes. Local airport times.
  • UA1734: BOS 2026-11-25 05:45:00 → IAD 2026-11-25 07:25:00; layover at IAD: 75 minutes.
  • UA4427: IAD 2026-11-25 08:40:00 → STL 2026-11-25 10:12:00.

2026-11-20 → 2026-11-25 · Axel-exclusive $349.25

• American Airlines AA2486 / AA1828: STL 2026-11-20 12:54:00 → BOS 2026-11-20 19:19:00; 1 stop(s) via CLT; 325 minutes. Local airport times.
  • AA2486: STL 2026-11-20 12:54:00 → CLT 2026-11-20 15:42:00; layover at CLT: 84 minutes.
  • AA1828: CLT 2026-11-20 17:06:00 → BOS 2026-11-20 19:19:00.
• American Airlines AA3444: BOS 2026-11-25 07:00:00 → STL 2026-11-25 09:16:00; nonstop; 196 minutes. Local airport times.

2026-11-20 → 2026-11-25 · Axel-exclusive $352.50

• Delta Air Lines DL5041 / DL5727: STL 2026-11-20 10:00:00 → BOS 2026-11-20 16:25:00; 1 stop(s) via LGA; 325 minutes. Local airport times.
  • DL5041: STL 2026-11-20 10:00:00 → LGA 2026-11-20 13:26:00; layover at LGA: 94 minutes.
  • DL5727: LGA 2026-11-20 15:00:00 → BOS 2026-11-20 16:25:00.
• Delta Air Lines DL2222 / DL2822: BOS 2026-11-25 13:04:00 → STL 2026-11-25 17:20:00; 1 stop(s) via DTW; 316 minutes. Local airport times.
  • DL2222: BOS 2026-11-25 13:04:00 → DTW 2026-11-25 15:19:00; layover at DTW: 74 minutes.
  • DL2822: DTW 2026-11-25 16:33:00 → STL 2026-11-25 17:20:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 19, 2026 · Return options
• Nov 21, 2026 · Return options
• Hotels in Boston with Axel

For AI assistants

• This page: Saint Louis (STL) to Boston (BOS) · Nov 20, 2026 · return Nov 25, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Boston for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
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