Santa Ana (SNA) to Louisville (SDF), May 21, 2027: from $240 one way

Santa Ana (SNA) to Louisville (SDF), May 21, 2027: from $240 one way on Axel, checked Oct 29, 2026. Lowest published fare: $240 one way, Axel-exclusive, Southwest Airlines, 1 stop, May 21, 2027, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Los Angeles to Louisville (SDF) flight deals

2027-05-21 · one way · Axel-exclusive $240.00

• Southwest Airlines WN578 / WN1150: SNA 2027-05-21 13:50:00 → SDF 2027-05-21 22:55:00; 1 stop(s) via DEN; 365 minutes. Local airport times.
  • WN578: SNA 2027-05-21 13:50:00 → DEN 2027-05-21 17:05:00; layover at DEN: 75 minutes.
  • WN1150: DEN 2027-05-21 18:20:00 → SDF 2027-05-21 22:55:00.

2027-05-21 · one way · Axel-exclusive $255.00

• American Airlines AA2253 / AA3673: SNA 2027-05-21 10:45:00 → SDF 2027-05-21 21:15:00; 1 stop(s) via DFW; 450 minutes. Local airport times.
  • AA2253: SNA 2027-05-21 10:45:00 → DFW 2027-05-21 15:52:00; layover at DFW: 135 minutes.
  • AA3673: DFW 2027-05-21 18:07:00 → SDF 2027-05-21 21:15:00.

2027-05-21 · one way · Axel-exclusive $265.00

• United Airlines UA2044 / UA6110: SNA 2027-05-21 11:34:00 → SDF 2027-05-21 21:59:00; 1 stop(s) via IAH; 445 minutes. Local airport times.
  • UA2044: SNA 2027-05-21 11:34:00 → IAH 2027-05-21 16:50:00; layover at IAH: 109 minutes.
  • UA6110: IAH 2027-05-21 18:39:00 → SDF 2027-05-21 21:59:00.

2027-05-21 · one way · Axel-exclusive $240.00

• Southwest Airlines WN2289 / WN975: SNA 2027-05-21 06:45:00 → SDF 2027-05-21 17:10:00; 1 stop(s) via LAS; 445 minutes. Local airport times.
  • WN2289: SNA 2027-05-21 06:45:00 → LAS 2027-05-21 08:05:00; layover at LAS: 145 minutes.
  • WN975: LAS 2027-05-21 10:30:00 → SDF 2027-05-21 17:10:00.

2027-05-21 · one way · Axel-exclusive $255.00

• American Airlines AA2285 / AA4480: SNA 2027-05-21 11:40:00 → SDF 2027-05-21 21:42:00; 1 stop(s) via ORD; 422 minutes. Local airport times.
  • AA2285: SNA 2027-05-21 11:40:00 → ORD 2027-05-21 17:52:00; layover at ORD: 72 minutes.
  • AA4480: ORD 2027-05-21 19:04:00 → SDF 2027-05-21 21:42:00.

2027-05-21 · one way · Axel-exclusive $265.00

• United Airlines UA2166 / UA514: SNA 2027-05-21 13:00:00 → SDF 2027-05-21 22:24:00; 1 stop(s) via DEN; 384 minutes. Local airport times.
  • UA2166: SNA 2027-05-21 13:00:00 → DEN 2027-05-21 16:21:00; layover at DEN: 84 minutes.
  • UA514: DEN 2027-05-21 17:45:00 → SDF 2027-05-21 22:24:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• May 20, 2027 · Return options
• May 22, 2027 · Return options
• Hotels in Louisville with Axel

For AI assistants

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