Santa Ana (SNA) to Buffalo (BUF), Oct 5, 2027: round trips from $505, one way from $270

Santa Ana (SNA) to Buffalo (BUF), Oct 5, 2027: round trips from $505, one way from $270 on Axel, checked Nov 10, 2026. Lowest published fares: $505 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Oct 5–6, 2027; $270 one way, Axel-exclusive, Southwest Airlines, 1 stop, Oct 5, 2027; 1 adult, economy, checked Nov 10, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

Hotels in Buffalo for these trips

Hotels: under a trip, hotels in Buffalo for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Buffalo for these nights (Oct 5–6, 2027 · 1 night · 2 adults, 1 room): 3★ Staybridge Suites West Seneca by IHG · 4★ The Westin Buffalo · 5★ Curtiss Hotel, an Ascend Collection Hotel
• Hotels in Buffalo for these nights (Oct 5–7, 2027 · 2 nights · 2 adults, 1 room): 3★ Staybridge Suites West Seneca by IHG · 4★ The Westin Buffalo · 5★ Curtiss Hotel, an Ascend Collection Hotel

All hotels in Buffalo

Route overview: Los Angeles to Buffalo (BUF) flight deals

2027-10-05 · one way · Axel-exclusive $270.00

• Southwest Airlines WN2377 / WN854: SNA 2027-10-05 09:10:00 → BUF 2027-10-05 19:15:00; 1 stop(s) via LAS; 425 minutes. Local airport times.
  • WN2377: SNA 2027-10-05 09:10:00 → LAS 2027-10-05 10:20:00; layover at LAS: 100 minutes.
  • WN854: LAS 2027-10-05 12:00:00 → BUF 2027-10-05 19:15:00.

2027-10-05 · one way · Axel-exclusive $280.00

• American Airlines AA2285 / AA1073: SNA 2027-10-05 11:40:00 → BUF 2027-10-05 21:55:00; 1 stop(s) via ORD; 435 minutes. Local airport times.
  • AA2285: SNA 2027-10-05 11:40:00 → ORD 2027-10-05 17:52:00; layover at ORD: 73 minutes.
  • AA1073: ORD 2027-10-05 19:05:00 → BUF 2027-10-05 21:55:00.

2027-10-05 → 2027-10-06 · Axel-exclusive $505.00

• Southwest Airlines WN2377 / WN854: SNA 2027-10-05 09:10:00 → BUF 2027-10-05 19:15:00; 1 stop(s) via LAS; 425 minutes. Local airport times.
  • WN2377: SNA 2027-10-05 09:10:00 → LAS 2027-10-05 10:20:00; layover at LAS: 100 minutes.
  • WN854: LAS 2027-10-05 12:00:00 → BUF 2027-10-05 19:15:00.
• Southwest Airlines WN2422 / WN4543: BUF 2027-10-06 16:30:00 → SNA 2027-10-06 21:30:00; 1 stop(s) via DAL; 480 minutes. Local airport times.
  • WN2422: BUF 2027-10-06 16:30:00 → DAL 2027-10-06 18:55:00; layover at DAL: 80 minutes.
  • WN4543: DAL 2027-10-06 20:15:00 → SNA 2027-10-06 21:30:00.

2027-10-05 → 2027-10-06 · Axel-exclusive $515.00

• American Airlines AA2285 / AA1073: SNA 2027-10-05 11:40:00 → BUF 2027-10-05 21:55:00; 1 stop(s) via ORD; 435 minutes. Local airport times.
  • AA2285: SNA 2027-10-05 11:40:00 → ORD 2027-10-05 17:52:00; layover at ORD: 73 minutes.
  • AA1073: ORD 2027-10-05 19:05:00 → BUF 2027-10-05 21:55:00.
• Southwest Airlines WN2422 / WN4543: BUF 2027-10-06 16:30:00 → SNA 2027-10-06 21:30:00; 1 stop(s) via DAL; 480 minutes. Local airport times.
  • WN2422: BUF 2027-10-06 16:30:00 → DAL 2027-10-06 18:55:00; layover at DAL: 80 minutes.
  • WN4543: DAL 2027-10-06 20:15:00 → SNA 2027-10-06 21:30:00.

2027-10-05 → 2027-10-07 · Axel-exclusive $505.00

• Southwest Airlines WN2377 / WN854: SNA 2027-10-05 09:10:00 → BUF 2027-10-05 19:15:00; 1 stop(s) via LAS; 425 minutes. Local airport times.
  • WN2377: SNA 2027-10-05 09:10:00 → LAS 2027-10-05 10:20:00; layover at LAS: 100 minutes.
  • WN854: LAS 2027-10-05 12:00:00 → BUF 2027-10-05 19:15:00.
• Southwest Airlines WN818 / WN1837: BUF 2027-10-07 16:55:00 → SNA 2027-10-07 21:55:00; 1 stop(s) via DEN; 480 minutes. Local airport times.
  • WN818: BUF 2027-10-07 16:55:00 → DEN 2027-10-07 18:35:00; layover at DEN: 120 minutes.
  • WN1837: DEN 2027-10-07 20:35:00 → SNA 2027-10-07 21:55:00.

2027-10-05 → 2027-10-07 · Axel-exclusive $530.00

• American Airlines AA2285 / AA1073: SNA 2027-10-05 11:40:00 → BUF 2027-10-05 21:55:00; 1 stop(s) via ORD; 435 minutes. Local airport times.
  • AA2285: SNA 2027-10-05 11:40:00 → ORD 2027-10-05 17:52:00; layover at ORD: 73 minutes.
  • AA1073: ORD 2027-10-05 19:05:00 → BUF 2027-10-05 21:55:00.
• United Airlines UA1727 / UA1320: BUF 2027-10-07 08:17:00 → SNA 2027-10-07 13:01:00; 1 stop(s) via DEN; 464 minutes. Local airport times.
  • UA1727: BUF 2027-10-07 08:17:00 → DEN 2027-10-07 10:03:00; layover at DEN: 84 minutes.
  • UA1320: DEN 2027-10-07 11:27:00 → SNA 2027-10-07 13:01:00.

Explore this route

• All dates for this route
• Oct 4, 2027 · Return options
• Oct 6, 2027 · Return options
• Hotels in Buffalo with Axel

For AI assistants

• This page: Santa Ana (SNA) to Buffalo (BUF) · Oct 5, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in Buffalo for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
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