San Francisco (SFO) to Saint Louis (STL), Nov 7–21, 2026: from $372 round trip

San Francisco (SFO) to Saint Louis (STL), Nov 7–21, 2026: from $372 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $372 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 7–21, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in St. Louis for these nights (Nov 7–21, 2026 · 14 nights · 2 adults, 1 room): 3★ Hampton Inn & Suites St. Louis at Forest Park · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis

All hotels in St. Louis

Route overview: San Francisco Bay Area to Saint Louis (STL) flight deals

2026-11-07 → 2026-11-21 · Axel-exclusive $391.00

• Southwest Airlines WN2989: SFO 2026-11-07 13:05:00 → STL 2026-11-07 18:55:00; nonstop; 230 minutes. Local airport times.
• Southwest Airlines WN4751: STL 2026-11-21 08:00:00 → SFO 2026-11-21 10:20:00; nonstop; 260 minutes. Local airport times.

2026-11-07 → 2026-11-21 · Axel-exclusive $460.00

• United Airlines UA5750: SFO 2026-11-07 23:00:00 → STL 2026-11-08 05:06:00; nonstop; 246 minutes. Local airport times.
• United Airlines UA214: STL 2026-11-21 19:05:00 → SFO 2026-11-21 21:41:00; nonstop; 276 minutes. Local airport times.

2026-11-07 → 2026-11-21 · Axel-exclusive $379.50

• American Airlines AA6214 / AA6209: SFO 2026-11-07 15:07:00 → STL 2026-11-07 23:36:00; 1 stop(s) via LAX; 389 minutes. Local airport times.
  • AA6214: SFO 2026-11-07 15:07:00 → LAX 2026-11-07 16:43:00; layover at LAX: 67 minutes.
  • AA6209: LAX 2026-11-07 17:50:00 → STL 2026-11-07 23:36:00.
• American Airlines AA2303 / AA2234: STL 2026-11-21 14:23:00 → SFO 2026-11-21 19:16:00; 1 stop(s) via PHX; 413 minutes. Local airport times.
  • AA2303: STL 2026-11-21 14:23:00 → PHX 2026-11-21 16:51:00; layover at PHX: 74 minutes.
  • AA2234: PHX 2026-11-21 18:05:00 → SFO 2026-11-21 19:16:00.

2026-11-07 → 2026-11-21 · Axel-exclusive $402.50

• Delta Air Lines DL920 / DL2373: SFO 2026-11-07 09:56:00 → STL 2026-11-07 17:41:00; 1 stop(s) via SLC; 345 minutes. Local airport times.
  • DL920: SFO 2026-11-07 09:56:00 → SLC 2026-11-07 12:50:00; layover at SLC: 65 minutes.
  • DL2373: SLC 2026-11-07 13:55:00 → STL 2026-11-07 17:41:00.
• Delta Air Lines DL1597 / DL2078: STL 2026-11-21 06:03:00 → SFO 2026-11-21 11:07:00; 1 stop(s) via MSP; 424 minutes. Local airport times.
  • DL1597: STL 2026-11-21 06:03:00 → MSP 2026-11-21 07:43:00; layover at MSP: 62 minutes.
  • DL2078: MSP 2026-11-21 08:45:00 → SFO 2026-11-21 11:07:00.

2026-11-07 → 2026-11-21 · Axel-exclusive $460.00

• United Airlines UA1588: SFO 2026-11-07 12:22:00 → STL 2026-11-07 18:17:00; nonstop; 235 minutes. Local airport times.
• United Airlines UA214: STL 2026-11-21 19:05:00 → SFO 2026-11-21 21:41:00; nonstop; 276 minutes. Local airport times.

2026-11-07 → 2026-11-21 · Axel-exclusive $371.50

• Southwest Airlines WN2989: SFO 2026-11-07 11:15:00 → STL 2026-11-07 17:10:00; nonstop; 235 minutes. Local airport times.
• Southwest Airlines WN2467 / WN1448: STL 2026-11-21 18:40:00 → SFO 2026-11-21 23:55:00; 1 stop(s) via PHX; 435 minutes. Local airport times.
  • WN2467: STL 2026-11-21 18:40:00 → PHX 2026-11-21 21:00:00; layover at PHX: 105 minutes.
  • WN1448: PHX 2026-11-21 22:45:00 → SFO 2026-11-21 23:55:00.

2026-11-07 → 2026-11-21 · Axel-exclusive $376.00

• Southwest Airlines WN3850 / WN709: SFO 2026-11-07 05:05:00 → STL 2026-11-07 13:00:00; 1 stop(s) via PHX; 355 minutes. Local airport times.
  • WN3850: SFO 2026-11-07 05:05:00 → PHX 2026-11-07 08:00:00; layover at PHX: 70 minutes.
  • WN709: PHX 2026-11-07 09:10:00 → STL 2026-11-07 13:00:00.
• Southwest Airlines WN4751: STL 2026-11-21 08:00:00 → SFO 2026-11-21 10:20:00; nonstop; 260 minutes. Local airport times.

2026-11-07 → 2026-11-21 · Axel-exclusive $376.00

• Southwest Airlines WN4578 / WN1807: SFO 2026-11-07 06:00:00 → STL 2026-11-07 13:30:00; 1 stop(s) via DEN; 330 minutes. Local airport times.
  • WN4578: SFO 2026-11-07 06:00:00 → DEN 2026-11-07 09:30:00; layover at DEN: 60 minutes.
  • WN1807: DEN 2026-11-07 10:30:00 → STL 2026-11-07 13:30:00.
• Southwest Airlines WN4751: STL 2026-11-21 08:00:00 → SFO 2026-11-21 10:20:00; nonstop; 260 minutes. Local airport times.

2026-11-07 → 2026-11-21 · Axel-exclusive $376.00

• Southwest Airlines WN1262 / WN738: SFO 2026-11-07 22:45:00 → STL 2026-11-08 07:40:00; 1 stop(s) via BNA; 415 minutes. Local airport times.
  • WN1262: SFO 2026-11-07 22:45:00 → BNA 2026-11-08 05:05:00; layover at BNA: 80 minutes.
  • WN738: BNA 2026-11-08 06:25:00 → STL 2026-11-08 07:40:00.
• Southwest Airlines WN4751: STL 2026-11-21 08:00:00 → SFO 2026-11-21 10:20:00; nonstop; 260 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 8, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: San Francisco (SFO) to Saint Louis (STL) · Nov 7, 2026 · return Nov 21, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
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• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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