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Route overview: San Francisco Bay Area to Santiago (SCL) flight deals

San Francisco (SFO) to Santiago (SCL), Dec 25, 2026: round trips from $1,269, one way from $891

San Francisco (SFO) to Santiago (SCL), Dec 25, 2026: round trips from $1,269, one way from $891 on Axel, checked Oct 29, 2026. Lowest published fares: $1,269 round trip, Axel-exclusive, Air Canada, 1 stop, Dec 25, 2026 – Jan 5, 2027; $891 one way, Axel-exclusive, Air Canada, 1 stop, Dec 25, 2026; 1 adult, economy, checked Oct 29, 2026.

SFO → SCL1 adulteconomyOne way and round trips

32 flight options · 4 airlines

Choose your return date

One-way flights and round trips by duration. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

December 2026

Flights for your trip

  1. Fri, Dec 25 · One way

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL

    One-way total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  2. Fri, Dec 25 · One way

    American Airlines
    12:02 pmSFO
    16h 13m
    MIA · 2h 7m
    9:15 am+1SCL

    One-way total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  3. Fri, Dec 25 – Sun, Dec 27

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  4. Fri, Dec 25 – Sun, Dec 27

    United Airlines
    11:04 amSFO
    16h 46m
    IAH · 3h 26m
    8:50 am+1SCL
    Copa Airlines
    12:20 pmSCL
    15h 55m
    PTY · 1h 20m
    11:15 pmSFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  5. Fri, Dec 25 – Mon, Dec 28

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  6. Fri, Dec 25 – Mon, Dec 28

    United Airlines
    11:04 amSFO
    16h 46m
    IAH · 3h 26m
    8:50 am+1SCL
    Copa Airlines
    12:20 pmSCL
    15h 55m
    PTY · 1h 20m
    11:15 pmSFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  7. Fri, Dec 25 – Tue, Dec 29

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  8. Fri, Dec 25 – Tue, Dec 29

    American Airlines
    12:02 pmSFO
    16h 13m
    MIA · 2h 7m
    9:15 am+1SCL
    American Airlines
    10:30 pmSCL
    17h 26m
    MIA · 2h 30m
    10:56 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  9. Fri, Dec 25 – Thu, Dec 31

    United Airlines
    11:04 amSFO
    16h 46m
    IAH · 3h 26m
    8:50 am+1SCL
    Copa Airlines
    12:20 pmSCL
    15h 55m
    PTY · 1h 20m
    11:15 pmSFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  10. Fri, Dec 25 – Thu, Dec 31

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  11. Fri, Dec 25 – Fri, Jan 1

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  12. Fri, Dec 25 – Fri, Jan 1

    United Airlines
    11:04 amSFO
    16h 46m
    IAH · 3h 26m
    8:50 am+1SCL
    Copa Airlines
    12:20 pmSCL
    15h 55m
    PTY · 1h 20m
    11:15 pmSFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  13. Fri, Dec 25 – Sun, Jan 3

    United Airlines
    11:04 amSFO
    16h 46m
    IAH · 3h 26m
    8:50 am+1SCL
    Copa Airlines
    12:20 pmSCL
    15h 55m
    PTY · 1h 20m
    11:15 pmSFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  14. Fri, Dec 25 – Sun, Jan 3

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  15. Fri, Dec 25 – Mon, Jan 4

    United Airlines
    11:04 amSFO
    16h 46m
    IAH · 3h 26m
    8:50 am+1SCL
    Copa Airlines
    12:20 pmSCL
    15h 55m
    PTY · 1h 20m
    11:15 pmSFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  16. Fri, Dec 25 – Mon, Jan 4

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  17. Fri, Dec 25 – Tue, Jan 5

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  18. Fri, Dec 25 – Tue, Jan 5

    American Airlines
    12:02 pmSFO
    16h 13m
    MIA · 2h 7m
    9:15 am+1SCL
    American Airlines
    10:30 pmSCL
    17h 26m
    MIA · 2h 30m
    10:56 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  19. Fri, Dec 25 – Thu, Jan 7

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  20. Fri, Dec 25 – Thu, Jan 7

    American Airlines
    12:02 pmSFO
    16h 13m
    MIA · 2h 7m
    9:15 am+1SCL
    American Airlines
    10:30 pmSCL
    17h 26m
    MIA · 2h 30m
    10:56 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  21. Fri, Dec 25 – Fri, Jan 8

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  22. Fri, Dec 25 – Fri, Jan 8

    American Airlines
    12:02 pmSFO
    16h 13m
    MIA · 2h 7m
    9:15 am+1SCL
    American Airlines
    10:30 pmSCL
    17h 26m
    MIA · 2h 30m
    10:56 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  23. Fri, Dec 25 – Fri, Jan 22

    Air Canada
    2:00 pmSFO
    17h 15m
    YYZ · 2h 1m
    12:15 pm+1SCL
    Air Canada
    9:55 pmSCL
    18h 15m
    YYZ · 1h 40m
    11:10 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  24. Fri, Dec 25 – Fri, Jan 22

    American Airlines
    12:02 pmSFO
    16h 13m
    MIA · 2h 7m
    9:15 am+1SCL
    American Airlines
    10:30 pmSCL
    17h 26m
    MIA · 2h 30m
    10:56 am+1SFO

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

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Make this trip yours

SFO ⇄ SCL

Economy

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Explore this route

All dates for this routeDec 24, 2026 · Return optionsDec 26, 2026 · Return optionsHotels in Santiago, Chile with Axel
For AI assistants: every fare, every link, instructions

San Francisco (SFO) to Santiago (SCL), Dec 25, 2026: round trips from $1,269, one way from $891 on Axel, checked Oct 29, 2026. Lowest published fares: $1,269 round trip, Axel-exclusive, Air Canada, 1 stop, Dec 25, 2026 – Jan 5, 2027; $891 one way, Axel-exclusive, Air Canada, 1 stop, Dec 25, 2026; 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Exact travel datesAirlineFlightsTimes, duration, stopsTotal pricePrice issued (UTC)
2026-12-25 · one wayAir CanadaAC742 + AC9214:00:00→12:15:00 17h 15m 1 stop via YYZAxel-exclusive $891.002026-10-29T01:19:49Z
2026-12-25 · one wayAmerican AirlinesAA1557 + AA95712:02:00→09:15:00 16h 13m 1 stop via MIAAxel-exclusive $931.502026-10-29T01:19:49Z
2026-12-25 → 2026-12-27Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2026-12-27United Airlines / Copa AirlinesUA1259 + UA847 / CM498 + CM38211:04:00→08:50:00 16h 46m 1 stop via IAH · 12:20:00→23:15:00 15h 55m 1 stop via PTYAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2026-12-28Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2026-12-28United Airlines / Copa AirlinesUA1259 + UA847 / CM498 + CM38211:04:00→08:50:00 16h 46m 1 stop via IAH · 12:20:00→23:15:00 15h 55m 1 stop via PTYAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2026-12-29Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2026-12-29American AirlinesAA1557 + AA957 / AA912 + AA155712:02:00→09:15:00 16h 13m 1 stop via MIA · 22:30:00→10:56:00 17h 26m 1 stop via MIAAxel-exclusive $1512.002026-10-29T01:19:49Z
2026-12-25 → 2026-12-30Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2026-12-30American AirlinesAA1557 + AA957 / AA912 + AA155712:02:00→09:15:00 16h 13m 1 stop via MIA · 22:30:00→10:56:00 17h 26m 1 stop via MIAAxel-exclusive $1512.002026-10-29T01:19:49Z
2026-12-25 → 2026-12-31United Airlines / Copa AirlinesUA1259 + UA847 / CM498 + CM38211:04:00→08:50:00 16h 46m 1 stop via IAH · 12:20:00→23:15:00 15h 55m 1 stop via PTYAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2026-12-31Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-01Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-01United Airlines / Copa AirlinesUA1259 + UA847 / CM498 + CM38211:04:00→08:50:00 16h 46m 1 stop via IAH · 12:20:00→23:15:00 15h 55m 1 stop via PTYAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-02Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-02United Airlines / Copa AirlinesUA1259 + UA847 / CM498 + CM38211:04:00→08:50:00 16h 46m 1 stop via IAH · 12:20:00→23:15:00 15h 55m 1 stop via PTYAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-03United Airlines / Copa AirlinesUA1259 + UA847 / CM498 + CM38211:04:00→08:50:00 16h 46m 1 stop via IAH · 12:20:00→23:15:00 15h 55m 1 stop via PTYAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-03Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-04United Airlines / Copa AirlinesUA1259 + UA847 / CM498 + CM38211:04:00→08:50:00 16h 46m 1 stop via IAH · 12:20:00→23:15:00 15h 55m 1 stop via PTYAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-04Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1458.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-05Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1269.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-05American AirlinesAA1557 + AA957 / AA912 + AA155712:02:00→09:15:00 16h 13m 1 stop via MIA · 22:30:00→10:56:00 17h 26m 1 stop via MIAAxel-exclusive $1316.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-06Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1269.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-06American AirlinesAA1557 + AA957 / AA912 + AA155712:02:00→09:15:00 16h 13m 1 stop via MIA · 22:30:00→10:56:00 17h 26m 1 stop via MIAAxel-exclusive $1316.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-07Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1269.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-07American AirlinesAA1557 + AA957 / AA912 + AA155712:02:00→09:15:00 16h 13m 1 stop via MIA · 22:30:00→10:56:00 17h 26m 1 stop via MIAAxel-exclusive $1316.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-08Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1269.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-08American AirlinesAA1557 + AA957 / AA912 + AA155712:02:00→09:15:00 16h 13m 1 stop via MIA · 22:30:00→10:56:00 17h 26m 1 stop via MIAAxel-exclusive $1316.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-15Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1269.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-15American AirlinesAA1557 + AA957 / AA912 + AA155712:02:00→09:15:00 16h 13m 1 stop via MIA · 22:30:00→10:56:00 17h 26m 1 stop via MIAAxel-exclusive $1316.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-22Air CanadaAC742 + AC92 / AC93 + AC73914:00:00→12:15:00 17h 15m 1 stop via YYZ · 21:55:00→11:10:00 18h 15m 1 stop via YYZAxel-exclusive $1269.002026-10-29T01:19:49Z
2026-12-25 → 2027-01-22American AirlinesAA1557 + AA957 / AA912 + AA155712:02:00→09:15:00 16h 13m 1 stop via MIA · 22:30:00→10:56:00 17h 26m 1 stop via MIAAxel-exclusive $1316.002026-10-29T01:19:49Z

Hotels in Santiago, Chile for these trips

Hotels: under a trip, hotels in Santiago, Chile for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

All hotels in Santiago, Chile

Route overview: San Francisco Bay Area to Santiago (SCL) flight deals

2026-12-25 · one way · Axel-exclusive $891.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.

2026-12-25 · one way · Axel-exclusive $931.50

  • American Airlines AA1557 / AA957: SFO 2026-12-25 12:02:00 → SCL 2026-12-26 09:15:00; 1 stop(s) via MIA; 973 minutes. Local airport times.
    • AA1557: SFO 2026-12-25 12:02:00 → MIA 2026-12-25 20:43:00; layover at MIA: 127 minutes.
    • AA957: MIA 2026-12-25 22:50:00 → SCL 2026-12-26 09:15:00.

2026-12-25 → 2026-12-27 · Axel-exclusive $1458.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2026-12-27 21:55:00 → SFO 2026-12-28 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2026-12-27 21:55:00 → YYZ 2026-12-28 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2026-12-28 08:20:00 → SFO 2026-12-28 11:10:00.

2026-12-25 → 2026-12-27 · Axel-exclusive $1458.00

  • United Airlines UA1259 / UA847: SFO 2026-12-25 11:04:00 → SCL 2026-12-26 08:50:00; 1 stop(s) via IAH; 1006 minutes. Local airport times.
    • UA1259: SFO 2026-12-25 11:04:00 → IAH 2026-12-25 17:04:00; layover at IAH: 206 minutes.
    • UA847: IAH 2026-12-25 20:30:00 → SCL 2026-12-26 08:50:00.
  • Copa Airlines CM498 / CM382: SCL 2026-12-27 12:20:00 → SFO 2026-12-27 23:15:00; 1 stop(s) via PTY; 955 minutes. Local airport times.
    • CM498: SCL 2026-12-27 12:20:00 → PTY 2026-12-27 17:11:00; layover at PTY: 80 minutes.
    • CM382: PTY 2026-12-27 18:31:00 → SFO 2026-12-27 23:15:00.

2026-12-25 → 2026-12-28 · Axel-exclusive $1458.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2026-12-28 21:55:00 → SFO 2026-12-29 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2026-12-28 21:55:00 → YYZ 2026-12-29 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2026-12-29 08:20:00 → SFO 2026-12-29 11:10:00.

2026-12-25 → 2026-12-28 · Axel-exclusive $1458.00

  • United Airlines UA1259 / UA847: SFO 2026-12-25 11:04:00 → SCL 2026-12-26 08:50:00; 1 stop(s) via IAH; 1006 minutes. Local airport times.
    • UA1259: SFO 2026-12-25 11:04:00 → IAH 2026-12-25 17:04:00; layover at IAH: 206 minutes.
    • UA847: IAH 2026-12-25 20:30:00 → SCL 2026-12-26 08:50:00.
  • Copa Airlines CM498 / CM382: SCL 2026-12-28 12:20:00 → SFO 2026-12-28 23:15:00; 1 stop(s) via PTY; 955 minutes. Local airport times.
    • CM498: SCL 2026-12-28 12:20:00 → PTY 2026-12-28 17:11:00; layover at PTY: 80 minutes.
    • CM382: PTY 2026-12-28 18:31:00 → SFO 2026-12-28 23:15:00.

2026-12-25 → 2026-12-29 · Axel-exclusive $1458.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2026-12-29 21:55:00 → SFO 2026-12-30 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2026-12-29 21:55:00 → YYZ 2026-12-30 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2026-12-30 08:20:00 → SFO 2026-12-30 11:10:00.

2026-12-25 → 2026-12-29 · Axel-exclusive $1512.00

  • American Airlines AA1557 / AA957: SFO 2026-12-25 12:02:00 → SCL 2026-12-26 09:15:00; 1 stop(s) via MIA; 973 minutes. Local airport times.
    • AA1557: SFO 2026-12-25 12:02:00 → MIA 2026-12-25 20:43:00; layover at MIA: 127 minutes.
    • AA957: MIA 2026-12-25 22:50:00 → SCL 2026-12-26 09:15:00.
  • American Airlines AA912 / AA1557: SCL 2026-12-29 22:30:00 → SFO 2026-12-30 10:56:00; 1 stop(s) via MIA; 1046 minutes. Local airport times.
    • AA912: SCL 2026-12-29 22:30:00 → MIA 2026-12-30 05:00:00; layover at MIA: 150 minutes.
    • AA1557: MIA 2026-12-30 07:30:00 → SFO 2026-12-30 10:56:00.

2026-12-25 → 2026-12-31 · Axel-exclusive $1458.00

  • United Airlines UA1259 / UA847: SFO 2026-12-25 11:04:00 → SCL 2026-12-26 08:50:00; 1 stop(s) via IAH; 1006 minutes. Local airport times.
    • UA1259: SFO 2026-12-25 11:04:00 → IAH 2026-12-25 17:04:00; layover at IAH: 206 minutes.
    • UA847: IAH 2026-12-25 20:30:00 → SCL 2026-12-26 08:50:00.
  • Copa Airlines CM498 / CM382: SCL 2026-12-31 12:20:00 → SFO 2026-12-31 23:15:00; 1 stop(s) via PTY; 955 minutes. Local airport times.
    • CM498: SCL 2026-12-31 12:20:00 → PTY 2026-12-31 17:11:00; layover at PTY: 80 minutes.
    • CM382: PTY 2026-12-31 18:31:00 → SFO 2026-12-31 23:15:00.

2026-12-25 → 2026-12-31 · Axel-exclusive $1458.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2026-12-31 21:55:00 → SFO 2027-01-01 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2026-12-31 21:55:00 → YYZ 2027-01-01 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2027-01-01 08:20:00 → SFO 2027-01-01 11:10:00.

2026-12-25 → 2027-01-01 · Axel-exclusive $1458.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2027-01-01 21:55:00 → SFO 2027-01-02 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2027-01-01 21:55:00 → YYZ 2027-01-02 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2027-01-02 08:20:00 → SFO 2027-01-02 11:10:00.

2026-12-25 → 2027-01-01 · Axel-exclusive $1458.00

  • United Airlines UA1259 / UA847: SFO 2026-12-25 11:04:00 → SCL 2026-12-26 08:50:00; 1 stop(s) via IAH; 1006 minutes. Local airport times.
    • UA1259: SFO 2026-12-25 11:04:00 → IAH 2026-12-25 17:04:00; layover at IAH: 206 minutes.
    • UA847: IAH 2026-12-25 20:30:00 → SCL 2026-12-26 08:50:00.
  • Copa Airlines CM498 / CM382: SCL 2027-01-01 12:20:00 → SFO 2027-01-01 23:15:00; 1 stop(s) via PTY; 955 minutes. Local airport times.
    • CM498: SCL 2027-01-01 12:20:00 → PTY 2027-01-01 17:11:00; layover at PTY: 80 minutes.
    • CM382: PTY 2027-01-01 18:31:00 → SFO 2027-01-01 23:15:00.

2026-12-25 → 2027-01-03 · Axel-exclusive $1458.00

  • United Airlines UA1259 / UA847: SFO 2026-12-25 11:04:00 → SCL 2026-12-26 08:50:00; 1 stop(s) via IAH; 1006 minutes. Local airport times.
    • UA1259: SFO 2026-12-25 11:04:00 → IAH 2026-12-25 17:04:00; layover at IAH: 206 minutes.
    • UA847: IAH 2026-12-25 20:30:00 → SCL 2026-12-26 08:50:00.
  • Copa Airlines CM498 / CM382: SCL 2027-01-03 12:20:00 → SFO 2027-01-03 23:15:00; 1 stop(s) via PTY; 955 minutes. Local airport times.
    • CM498: SCL 2027-01-03 12:20:00 → PTY 2027-01-03 17:11:00; layover at PTY: 80 minutes.
    • CM382: PTY 2027-01-03 18:31:00 → SFO 2027-01-03 23:15:00.

2026-12-25 → 2027-01-03 · Axel-exclusive $1458.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2027-01-03 21:55:00 → SFO 2027-01-04 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2027-01-03 21:55:00 → YYZ 2027-01-04 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2027-01-04 08:20:00 → SFO 2027-01-04 11:10:00.

2026-12-25 → 2027-01-04 · Axel-exclusive $1458.00

  • United Airlines UA1259 / UA847: SFO 2026-12-25 11:04:00 → SCL 2026-12-26 08:50:00; 1 stop(s) via IAH; 1006 minutes. Local airport times.
    • UA1259: SFO 2026-12-25 11:04:00 → IAH 2026-12-25 17:04:00; layover at IAH: 206 minutes.
    • UA847: IAH 2026-12-25 20:30:00 → SCL 2026-12-26 08:50:00.
  • Copa Airlines CM498 / CM382: SCL 2027-01-04 12:20:00 → SFO 2027-01-04 23:15:00; 1 stop(s) via PTY; 955 minutes. Local airport times.
    • CM498: SCL 2027-01-04 12:20:00 → PTY 2027-01-04 17:11:00; layover at PTY: 80 minutes.
    • CM382: PTY 2027-01-04 18:31:00 → SFO 2027-01-04 23:15:00.

2026-12-25 → 2027-01-04 · Axel-exclusive $1458.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2027-01-04 21:55:00 → SFO 2027-01-05 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2027-01-04 21:55:00 → YYZ 2027-01-05 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2027-01-05 08:20:00 → SFO 2027-01-05 11:10:00.

2026-12-25 → 2027-01-05 · Axel-exclusive $1269.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2027-01-05 21:55:00 → SFO 2027-01-06 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2027-01-05 21:55:00 → YYZ 2027-01-06 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2027-01-06 08:20:00 → SFO 2027-01-06 11:10:00.

2026-12-25 → 2027-01-05 · Axel-exclusive $1316.00

  • American Airlines AA1557 / AA957: SFO 2026-12-25 12:02:00 → SCL 2026-12-26 09:15:00; 1 stop(s) via MIA; 973 minutes. Local airport times.
    • AA1557: SFO 2026-12-25 12:02:00 → MIA 2026-12-25 20:43:00; layover at MIA: 127 minutes.
    • AA957: MIA 2026-12-25 22:50:00 → SCL 2026-12-26 09:15:00.
  • American Airlines AA912 / AA1557: SCL 2027-01-05 22:30:00 → SFO 2027-01-06 10:56:00; 1 stop(s) via MIA; 1046 minutes. Local airport times.
    • AA912: SCL 2027-01-05 22:30:00 → MIA 2027-01-06 05:00:00; layover at MIA: 150 minutes.
    • AA1557: MIA 2027-01-06 07:30:00 → SFO 2027-01-06 10:56:00.

2026-12-25 → 2027-01-07 · Axel-exclusive $1269.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2027-01-07 21:55:00 → SFO 2027-01-08 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2027-01-07 21:55:00 → YYZ 2027-01-08 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2027-01-08 08:20:00 → SFO 2027-01-08 11:10:00.

2026-12-25 → 2027-01-07 · Axel-exclusive $1316.00

  • American Airlines AA1557 / AA957: SFO 2026-12-25 12:02:00 → SCL 2026-12-26 09:15:00; 1 stop(s) via MIA; 973 minutes. Local airport times.
    • AA1557: SFO 2026-12-25 12:02:00 → MIA 2026-12-25 20:43:00; layover at MIA: 127 minutes.
    • AA957: MIA 2026-12-25 22:50:00 → SCL 2026-12-26 09:15:00.
  • American Airlines AA912 / AA1557: SCL 2027-01-07 22:30:00 → SFO 2027-01-08 10:56:00; 1 stop(s) via MIA; 1046 minutes. Local airport times.
    • AA912: SCL 2027-01-07 22:30:00 → MIA 2027-01-08 05:00:00; layover at MIA: 150 minutes.
    • AA1557: MIA 2027-01-08 07:30:00 → SFO 2027-01-08 10:56:00.

2026-12-25 → 2027-01-08 · Axel-exclusive $1269.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2027-01-08 21:55:00 → SFO 2027-01-09 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2027-01-08 21:55:00 → YYZ 2027-01-09 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2027-01-09 08:20:00 → SFO 2027-01-09 11:10:00.

2026-12-25 → 2027-01-08 · Axel-exclusive $1316.00

  • American Airlines AA1557 / AA957: SFO 2026-12-25 12:02:00 → SCL 2026-12-26 09:15:00; 1 stop(s) via MIA; 973 minutes. Local airport times.
    • AA1557: SFO 2026-12-25 12:02:00 → MIA 2026-12-25 20:43:00; layover at MIA: 127 minutes.
    • AA957: MIA 2026-12-25 22:50:00 → SCL 2026-12-26 09:15:00.
  • American Airlines AA912 / AA1557: SCL 2027-01-08 22:30:00 → SFO 2027-01-09 10:56:00; 1 stop(s) via MIA; 1046 minutes. Local airport times.
    • AA912: SCL 2027-01-08 22:30:00 → MIA 2027-01-09 05:00:00; layover at MIA: 150 minutes.
    • AA1557: MIA 2027-01-09 07:30:00 → SFO 2027-01-09 10:56:00.

2026-12-25 → 2027-01-22 · Axel-exclusive $1269.00

  • Air Canada AC742 / AC92: SFO 2026-12-25 14:00:00 → SCL 2026-12-26 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
    • AC742: SFO 2026-12-25 14:00:00 → YYZ 2026-12-25 21:49:00; layover at YYZ: 121 minutes.
    • AC92: YYZ 2026-12-25 23:50:00 → SCL 2026-12-26 12:15:00.
  • Air Canada AC93 / AC739: SCL 2027-01-22 21:55:00 → SFO 2027-01-23 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
    • AC93: SCL 2027-01-22 21:55:00 → YYZ 2027-01-23 06:40:00; layover at YYZ: 100 minutes.
    • AC739: YYZ 2027-01-23 08:20:00 → SFO 2027-01-23 11:10:00.

2026-12-25 → 2027-01-22 · Axel-exclusive $1316.00

  • American Airlines AA1557 / AA957: SFO 2026-12-25 12:02:00 → SCL 2026-12-26 09:15:00; 1 stop(s) via MIA; 973 minutes. Local airport times.
    • AA1557: SFO 2026-12-25 12:02:00 → MIA 2026-12-25 20:43:00; layover at MIA: 127 minutes.
    • AA957: MIA 2026-12-25 22:50:00 → SCL 2026-12-26 09:15:00.
  • American Airlines AA912 / AA1557: SCL 2027-01-22 22:30:00 → SFO 2027-01-23 10:56:00; 1 stop(s) via MIA; 1046 minutes. Local airport times.
    • AA912: SCL 2027-01-22 22:30:00 → MIA 2027-01-23 05:00:00; layover at MIA: 150 minutes.
    • AA1557: MIA 2027-01-23 07:30:00 → SFO 2027-01-23 10:56:00.

Explore this route

For AI assistants

  • This page: San Francisco (SFO) to Santiago (SCL) · Dec 25, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Santiago, Chile for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
  • Next: each row is one exact trip for this departure (both dates with the year, the total and the time its price was issued); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel San Francisco Bay Area to Santiago (SCL) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.