San Francisco (SFO) to Santiago (SCL), Dec 24, 2026 – Jan 3, 2027: from $1,458 round trip

San Francisco (SFO) to Santiago (SCL), Dec 24, 2026 – Jan 3, 2027: from $1,458 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $1,458 round trip, Axel-exclusive, United Airlines / Copa Airlines, 1 stop, Dec 24, 2026 – Jan 3, 2027, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Santiago, Chile for these trips

Hotels: under a trip, hotels in Santiago, Chile for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Santiago, Chile for these nights (Dec 24 – Jan 3, 2027 · 10 nights · 2 adults, 1 room): 3★ Hotel Santa Lucia, $406 total · 4★ Hotel Casa Zañartu, $389 total · 5★ Pullman Santiago Vitacura, $810 total

All hotels in Santiago, Chile

Route overview: San Francisco Bay Area to Santiago (SCL) flight deals

2026-12-24 → 2027-01-03 · Axel-exclusive $1458.00

• United Airlines UA1259 / UA847: SFO 2026-12-24 11:04:00 → SCL 2026-12-25 08:50:00; 1 stop(s) via IAH; 1006 minutes. Local airport times.
  • UA1259: SFO 2026-12-24 11:04:00 → IAH 2026-12-24 17:04:00; layover at IAH: 206 minutes.
  • UA847: IAH 2026-12-24 20:30:00 → SCL 2026-12-25 08:50:00.
• Copa Airlines CM498 / CM382: SCL 2027-01-03 12:20:00 → SFO 2027-01-03 23:15:00; 1 stop(s) via PTY; 955 minutes. Local airport times.
  • CM498: SCL 2027-01-03 12:20:00 → PTY 2027-01-03 17:11:00; layover at PTY: 80 minutes.
  • CM382: PTY 2027-01-03 18:31:00 → SFO 2027-01-03 23:15:00.

2026-12-24 → 2027-01-03 · Axel-exclusive $1458.00

• Air Canada AC742 / AC92: SFO 2026-12-24 14:00:00 → SCL 2026-12-25 12:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
  • AC742: SFO 2026-12-24 14:00:00 → YYZ 2026-12-24 21:49:00; layover at YYZ: 121 minutes.
  • AC92: YYZ 2026-12-24 23:50:00 → SCL 2026-12-25 12:15:00.
• Air Canada AC93 / AC739: SCL 2027-01-03 21:55:00 → SFO 2027-01-04 11:10:00; 1 stop(s) via YYZ; 1095 minutes. Local airport times.
  • AC93: SCL 2027-01-03 21:55:00 → YYZ 2027-01-04 06:40:00; layover at YYZ: 100 minutes.
  • AC739: YYZ 2027-01-04 08:20:00 → SFO 2027-01-04 11:10:00.

2026-12-24 → 2027-01-03 · Axel-exclusive $1512.00

• American Airlines AA1557 / AA957: SFO 2026-12-24 12:02:00 → SCL 2026-12-25 09:15:00; 1 stop(s) via MIA; 973 minutes. Local airport times.
  • AA1557: SFO 2026-12-24 12:02:00 → MIA 2026-12-24 20:43:00; layover at MIA: 127 minutes.
  • AA957: MIA 2026-12-24 22:50:00 → SCL 2026-12-25 09:15:00.
• American Airlines AA912 / AA1557: SCL 2027-01-03 22:30:00 → SFO 2027-01-04 10:56:00; 1 stop(s) via MIA; 1046 minutes. Local airport times.
  • AA912: SCL 2027-01-03 22:30:00 → MIA 2027-01-04 05:00:00; layover at MIA: 150 minutes.
  • AA1557: MIA 2027-01-04 07:30:00 → SFO 2027-01-04 10:56:00.

2026-12-24 → 2027-01-03 · Axel-exclusive $1593.00

• Delta Air Lines DL640 / DL297: SFO 2026-12-24 08:01:00 → SCL 2026-12-25 06:40:00; 1 stop(s) via ATL; 1059 minutes. Local airport times.
  • DL640: SFO 2026-12-24 08:01:00 → ATL 2026-12-24 15:32:00; layover at ATL: 213 minutes.
  • DL297: ATL 2026-12-24 19:05:00 → SCL 2026-12-25 06:40:00.
• Delta Air Lines DL296 / DL693: SCL 2027-01-03 21:50:00 → SFO 2027-01-04 10:35:00; 1 stop(s) via ATL; 1065 minutes. Local airport times.
  • DL296: SCL 2027-01-03 21:50:00 → ATL 2027-01-04 05:46:00; layover at ATL: 139 minutes.
  • DL693: ATL 2027-01-04 08:05:00 → SFO 2027-01-04 10:35:00.

2026-12-24 → 2027-01-03 · Axel-exclusive $1593.00

• Delta Air Lines DL1421 / LA603: SFO 2026-12-24 09:59:00 → SCL 2026-12-25 05:35:00; 1 stop(s) via LAX; 876 minutes. Local airport times.
  • DL1421: SFO 2026-12-24 09:59:00 → LAX 2026-12-24 11:29:00; layover at LAX: 146 minutes.
  • LA603: LAX 2026-12-24 13:55:00 → SCL 2026-12-25 05:35:00.
• Delta Air Lines DL296 / DL693: SCL 2027-01-03 21:50:00 → SFO 2027-01-04 10:35:00; 1 stop(s) via ATL; 1065 minutes. Local airport times.
  • DL296: SCL 2027-01-03 21:50:00 → ATL 2027-01-04 05:46:00; layover at ATL: 139 minutes.
  • DL693: ATL 2027-01-04 08:05:00 → SFO 2027-01-04 10:35:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Dec 23, 2026 · Return options
• Dec 25, 2026 · Return options
• Hotels in Santiago, Chile with Axel

For AI assistants

• This page: San Francisco (SFO) to Santiago (SCL) · Dec 24, 2026 · return Jan 3, 2027: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Santiago, Chile for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel San Francisco Bay Area to Santiago (SCL) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

Feedback (optional): Missing info · Axel issue