San Francisco (SFO) to Santiago (SCL), Apr 17, 2027: from $580 one way

San Francisco (SFO) to Santiago (SCL), Apr 17, 2027: from $580 one way on Axel, checked Oct 29, 2026. Lowest published fare: $580 one way, Axel-exclusive, Air Canada, 1 stop, Apr 17, 2027, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: San Francisco Bay Area to Santiago (SCL) flight deals

2027-04-17 · one way · Axel-exclusive $579.60

• Air Canada AC742 / AC92: SFO 2027-04-17 14:00:00 → SCL 2027-04-18 10:15:00; 1 stop(s) via YYZ; 1035 minutes. Local airport times.
  • AC742: SFO 2027-04-17 14:00:00 → YYZ 2027-04-17 21:49:00; layover at YYZ: 121 minutes.
  • AC92: YYZ 2027-04-17 23:50:00 → SCL 2027-04-18 10:15:00.

2027-04-17 · one way · Axel-exclusive $598.00

• American Airlines AA1557 / AA957: SFO 2027-04-17 12:02:00 → SCL 2027-04-18 07:15:00; 1 stop(s) via MIA; 973 minutes. Local airport times.
  • AA1557: SFO 2027-04-17 12:02:00 → MIA 2027-04-17 20:43:00; layover at MIA: 127 minutes.
  • AA957: MIA 2027-04-17 22:50:00 → SCL 2027-04-18 07:15:00.

2027-04-17 · one way · Axel-exclusive $607.20

• United Airlines UA1259 / UA847: SFO 2027-04-17 11:04:00 → SCL 2027-04-18 06:50:00; 1 stop(s) via IAH; 1006 minutes. Local airport times.
  • UA1259: SFO 2027-04-17 11:04:00 → IAH 2027-04-17 17:04:00; layover at IAH: 206 minutes.
  • UA847: IAH 2027-04-17 20:30:00 → SCL 2027-04-18 06:50:00.

2027-04-17 · one way · Axel-exclusive $625.60

• Delta Air Lines DL640 / DL297: SFO 2027-04-17 08:01:00 → SCL 2027-04-18 04:40:00; 1 stop(s) via ATL; 1059 minutes. Local airport times.
  • DL640: SFO 2027-04-17 08:01:00 → ATL 2027-04-17 15:32:00; layover at ATL: 213 minutes.
  • DL297: ATL 2027-04-17 19:05:00 → SCL 2027-04-18 04:40:00.

2027-04-17 · one way · Axel-exclusive $625.60

• Delta Air Lines DL1421 / LA603: SFO 2027-04-17 09:59:00 → SCL 2027-04-18 03:35:00; 1 stop(s) via LAX; 876 minutes. Local airport times.
  • DL1421: SFO 2027-04-17 09:59:00 → LAX 2027-04-17 11:29:00; layover at LAX: 146 minutes.
  • LA603: LAX 2027-04-17 13:55:00 → SCL 2027-04-18 03:35:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Apr 16, 2027 · Return options
• Apr 18, 2027 · Return options
• Hotels in Santiago, Chile with Axel

For AI assistants

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