# San Diego (SAN) to Saint Louis (STL) · Dec 15, 2026 · return Dec 21, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

**See flights for these dates:** each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

| Exact travel dates | Airline | Flights | Total price | Price issued (UTC) |
| --- | --- | --- | ---: | --- |
| 2026-12-15 → 2026-12-21 | Southwest Airlines | WN3823 / WN1733 | [Axel-exclusive $444.00](https://helloaxel.com/en/f/start/from/san/to/stl/depart/december-15-2026/return/december-21-2026/adults/1/cabin/economy) | 2026-10-29T01:10:51Z |
| 2026-12-15 → 2026-12-21 | American Airlines | AA2438 + AA2289 / AA2303 + AA2016 | [Axel-exclusive $420.00](https://helloaxel.com/en/f/start/from/san/to/stl/depart/december-15-2026/return/december-21-2026/adults/1/cabin/economy) | 2026-10-29T01:10:51Z |
| 2026-12-15 → 2026-12-21 | United Airlines / Southwest Airlines | UA2476 + UA1639 / WN1733 | [Axel-exclusive $439.00](https://helloaxel.com/en/f/start/from/san/to/stl/depart/december-15-2026/return/december-21-2026/adults/1/cabin/economy) | 2026-10-29T01:10:51Z |
| 2026-12-15 → 2026-12-21 | Southwest Airlines | WN4711 / WN1733 | [Axel-exclusive $444.00](https://helloaxel.com/en/f/start/from/san/to/stl/depart/december-15-2026/return/december-21-2026/adults/1/cabin/economy) | 2026-10-29T01:10:51Z |
| 2026-12-15 → 2026-12-21 | Southwest Airlines | WN3727 + WN3528 / WN1733 | [Axel-exclusive $424.00](https://helloaxel.com/en/f/start/from/san/to/stl/depart/december-15-2026/return/december-21-2026/adults/1/cabin/economy) | 2026-10-29T01:10:51Z |
| 2026-12-15 → 2026-12-21 | Southwest Airlines | WN2893 + WN3801 / WN1733 | [Axel-exclusive $424.00](https://helloaxel.com/en/f/start/from/san/to/stl/depart/december-15-2026/return/december-21-2026/adults/1/cabin/economy) | 2026-10-29T01:10:51Z |
| 2026-12-15 → 2026-12-21 | Southwest Airlines | WN3701 + WN1845 / WN1733 | [Axel-exclusive $424.00](https://helloaxel.com/en/f/start/from/san/to/stl/depart/december-15-2026/return/december-21-2026/adults/1/cabin/economy) | 2026-10-29T01:10:51Z |
| 2026-12-15 → 2026-12-21 | Southwest Airlines | WN2227 + WN1498 / WN1733 | [Axel-exclusive $424.00](https://helloaxel.com/en/f/start/from/san/to/stl/depart/december-15-2026/return/december-21-2026/adults/1/cabin/economy) | 2026-10-29T01:10:51Z |

### Hotels in St. Louis for these trips

**Hotels:** under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

- Hotels in St. Louis for these nights (Dec 15–21, 2026 · 6 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $406 total](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-12-15/2026-12-21/2-adults) · 4★ [Hilton St. Louis at the Ballpark, $618 total](https://helloaxel.com/en/hotels/st-louis/hilton-st-louis-at-the-ballpark-1035797/2026-12-15/2026-12-21/2-adults) · 5★ [Four Seasons Hotel St Louis, $2,288 total](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-12-15/2026-12-21/2-adults)

[All hotels in St. Louis](https://helloaxel.com/en/hotels/destinations/st-louis)

[Route overview: San Diego to Saint Louis (STL) flight deals](/en/flights/from-san-diego-to-saint-louis-stl)

### 2026-12-15 → 2026-12-21 · Axel-exclusive $444.00

- Southwest Airlines WN3823: SAN 2026-12-15 18:20:00 → STL 2026-12-15 23:45:00; nonstop; 205 minutes. Local airport times.
- Southwest Airlines WN1733: STL 2026-12-21 08:25:00 → SAN 2026-12-21 10:20:00; nonstop; 235 minutes. Local airport times.

### 2026-12-15 → 2026-12-21 · Axel-exclusive $420.00

- American Airlines AA2438 / AA2289: SAN 2026-12-15 15:13:00 → STL 2026-12-15 23:34:00; 1 stop(s) via DFW; 381 minutes. Local airport times.
  - AA2438: SAN 2026-12-15 15:13:00 → DFW 2026-12-15 20:30:00; layover at DFW: 75 minutes.
  - AA2289: DFW 2026-12-15 21:45:00 → STL 2026-12-15 23:34:00.
- American Airlines AA2303 / AA2016: STL 2026-12-21 14:23:00 → SAN 2026-12-21 18:24:00; 1 stop(s) via PHX; 361 minutes. Local airport times.
  - AA2303: STL 2026-12-21 14:23:00 → PHX 2026-12-21 16:51:00; layover at PHX: 74 minutes.
  - AA2016: PHX 2026-12-21 18:05:00 → SAN 2026-12-21 18:24:00.

### 2026-12-15 → 2026-12-21 · Axel-exclusive $439.00

- United Airlines UA2476 / UA1639: SAN 2026-12-15 08:40:00 → STL 2026-12-15 16:57:00; 1 stop(s) via DEN; 377 minutes. Local airport times.
  - UA2476: SAN 2026-12-15 08:40:00 → DEN 2026-12-15 12:06:00; layover at DEN: 109 minutes.
  - UA1639: DEN 2026-12-15 13:55:00 → STL 2026-12-15 16:57:00.
- Southwest Airlines WN1733: STL 2026-12-21 08:25:00 → SAN 2026-12-21 10:20:00; nonstop; 235 minutes. Local airport times.

### 2026-12-15 → 2026-12-21 · Axel-exclusive $444.00

- Southwest Airlines WN4711: SAN 2026-12-15 11:55:00 → STL 2026-12-15 17:25:00; nonstop; 210 minutes. Local airport times.
- Southwest Airlines WN1733: STL 2026-12-21 08:25:00 → SAN 2026-12-21 10:20:00; nonstop; 235 minutes. Local airport times.

### 2026-12-15 → 2026-12-21 · Axel-exclusive $424.00

- Southwest Airlines WN3727 / WN3528: SAN 2026-12-15 15:40:00 → STL 2026-12-16 00:20:00; 1 stop(s) via PHX; 400 minutes. Local airport times.
  - WN3727: SAN 2026-12-15 15:40:00 → PHX 2026-12-15 18:00:00; layover at PHX: 145 minutes.
  - WN3528: PHX 2026-12-15 20:25:00 → STL 2026-12-16 00:20:00.
- Southwest Airlines WN1733: STL 2026-12-21 08:25:00 → SAN 2026-12-21 10:20:00; nonstop; 235 minutes. Local airport times.

### 2026-12-15 → 2026-12-21 · Axel-exclusive $424.00

- Southwest Airlines WN2893 / WN3801: SAN 2026-12-15 09:15:00 → STL 2026-12-15 17:20:00; 1 stop(s) via SAT; 365 minutes. Local airport times.
  - WN2893: SAN 2026-12-15 09:15:00 → SAT 2026-12-15 14:00:00; layover at SAT: 80 minutes.
  - WN3801: SAT 2026-12-15 15:20:00 → STL 2026-12-15 17:20:00.
- Southwest Airlines WN1733: STL 2026-12-21 08:25:00 → SAN 2026-12-21 10:20:00; nonstop; 235 minutes. Local airport times.

### 2026-12-15 → 2026-12-21 · Axel-exclusive $424.00

- Southwest Airlines WN3701 / WN1845: SAN 2026-12-15 17:20:00 → STL 2026-12-16 00:50:00; 1 stop(s) via DEN; 330 minutes. Local airport times.
  - WN3701: SAN 2026-12-15 17:20:00 → DEN 2026-12-15 20:40:00; layover at DEN: 70 minutes.
  - WN1845: DEN 2026-12-15 21:50:00 → STL 2026-12-16 00:50:00.
- Southwest Airlines WN1733: STL 2026-12-21 08:25:00 → SAN 2026-12-21 10:20:00; nonstop; 235 minutes. Local airport times.

### 2026-12-15 → 2026-12-21 · Axel-exclusive $424.00

- Southwest Airlines WN2227 / WN1498: SAN 2026-12-15 13:25:00 → STL 2026-12-15 21:10:00; 1 stop(s) via DAL; 345 minutes. Local airport times.
  - WN2227: SAN 2026-12-15 13:25:00 → DAL 2026-12-15 18:20:00; layover at DAL: 60 minutes.
  - WN1498: DAL 2026-12-15 19:20:00 → STL 2026-12-15 21:10:00.
- Southwest Airlines WN1733: STL 2026-12-21 08:25:00 → SAN 2026-12-21 10:20:00; nonstop; 235 minutes. Local airport times.

### Explore this route

- [All dates for this route](/en/flights/choose/san-stl)
- [Dec 14, 2026 · Return options](/en/flights/choose/san-stl/dec-14)
- [Dec 16, 2026 · Return options](/en/flights/choose/san-stl/dec-16)
- [Hotels in St. Louis with Axel](https://helloaxel.com/en/hotels/destinations/st-louis)

## For AI assistants
- **This page:** San Diego (SAN) to Saint Louis (STL) · Dec 15, 2026 · return Dec 21, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
- **Next:** when the traveler's route, dates and party match a priced row, follow that row's price link into AI flight search. Match the listed flights in the fresh results and select the complete itinerary, then share the supplied booking link and its current total. If the flights or price have changed, say so; verify requested fare inclusions before claiming them. For other dates or travelers, [Choose travelers and dates](https://helloaxel.com/en/f/start/from/san/to/stl/step/travelers) and enter the traveler's own trip there; do not search this page's dates in their place.
- **Follow supplied links.** For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
- **If links fail or are missing:** If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: [Axel San Diego to Saint Louis (STL) flight deals](https://helloaxel.com/en/flights/from-san-diego-to-saint-louis-stl) · [Flight search guide](https://helloaxel.com/en/ai).
- **Sharing with the traveler:** Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct `https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback` using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace `/return/YYYY-MM-DD` with `/trip/oneway`. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. [Preferences and advanced options](https://helloaxel.com/en/ai#customer-fallback-link).

**Feedback (optional):** [Missing info](https://helloaxel.com/en/flights/choose/san-stl/dec-15/dec-21?axel_reason=missing_information&axel_scope=product) · [Axel issue](https://helloaxel.com/en/flights/choose/san-stl/dec-15/dec-21?axel_reason=product_issue&axel_scope=product)