San Diego (SAN) to Panama City (PTY) · Nov 21, 2026 · return Nov 24, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: San Diego to Panama City (PTY) flight deals

2026-11-21 → 2026-11-24 · Axel-exclusive $666.70

• American Airlines AA3304 / AA315: SAN 2026-11-21 22:45:00 → PTY 2026-11-22 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
  • AA3304: SAN 2026-11-21 22:45:00 → MIA 2026-11-22 06:44:00; layover at MIA: 223 minutes.
  • AA315: MIA 2026-11-22 10:27:00 → PTY 2026-11-22 13:41:00.
• American Airlines AA354 / AA1120: PTY 2026-11-24 14:41:00 → SAN 2026-11-24 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
  • AA354: PTY 2026-11-24 14:41:00 → MIA 2026-11-24 17:55:00; layover at MIA: 205 minutes.
  • AA1120: MIA 2026-11-24 21:20:00 → SAN 2026-11-24 23:59:00.

2026-11-21 → 2026-11-24 · Axel-exclusive $690.30

• United Airlines UA1329 / CM402: SAN 2026-11-21 06:20:00 → PTY 2026-11-21 20:39:00; 1 stop(s) via LAX; 679 minutes. Local airport times.
  • UA1329: SAN 2026-11-21 06:20:00 → LAX 2026-11-21 07:25:00; layover at LAX: 219 minutes.
  • CM402: LAX 2026-11-21 11:04:00 → PTY 2026-11-21 20:39:00.
• United Airlines UA1249 / UA2212: PTY 2026-11-24 08:55:00 → SAN 2026-11-24 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
  • UA1249: PTY 2026-11-24 08:55:00 → IAH 2026-11-24 12:15:00; layover at IAH: 130 minutes.
  • UA2212: IAH 2026-11-24 14:25:00 → SAN 2026-11-24 15:54:00.

2026-11-21 → 2026-11-24 · Axel-exclusive $702.10

• Delta Air Lines DL1179 / DL1905: SAN 2026-11-21 08:00:00 → PTY 2026-11-21 21:45:00; 1 stop(s) via ATL; 645 minutes. Local airport times.
  • DL1179: SAN 2026-11-21 08:00:00 → ATL 2026-11-21 15:16:00; layover at ATL: 147 minutes.
  • DL1905: ATL 2026-11-21 17:43:00 → PTY 2026-11-21 21:45:00.
• Delta Air Lines DL1758 / DL896: PTY 2026-11-24 15:28:00 → SAN 2026-11-24 23:40:00; 1 stop(s) via ATL; 672 minutes. Local airport times.
  • DL1758: PTY 2026-11-24 15:28:00 → ATL 2026-11-24 19:49:00; layover at ATL: 121 minutes.
  • DL896: ATL 2026-11-24 21:50:00 → SAN 2026-11-24 23:40:00.

2026-11-21 → 2026-11-24 · Axel-exclusive $755.20

• Copa Airlines CM850: SAN 2026-11-21 22:30:00 → PTY 2026-11-22 07:40:00; nonstop; 370 minutes. Local airport times.
• Copa Airlines CM476 / UA2395: PTY 2026-11-24 12:56:00 → SAN 2026-11-24 22:30:00; 1 stop(s) via DEN; 754 minutes. Local airport times.
  • CM476: PTY 2026-11-24 12:56:00 → DEN 2026-11-24 17:12:00; layover at DEN: 228 minutes.
  • UA2395: DEN 2026-11-24 21:00:00 → SAN 2026-11-24 22:30:00.

2026-11-21 → 2026-11-24 · Axel-exclusive $690.30

• United Airlines UA1577 / CM357: SAN 2026-11-21 21:45:00 → PTY 2026-11-22 13:31:00; 1 stop(s) via IAD; 766 minutes. Local airport times.
  • UA1577: SAN 2026-11-21 21:45:00 → IAD 2026-11-22 05:27:00; layover at IAD: 178 minutes.
  • CM357: IAD 2026-11-22 08:25:00 → PTY 2026-11-22 13:31:00.
• United Airlines UA1249 / UA2212: PTY 2026-11-24 08:55:00 → SAN 2026-11-24 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
  • UA1249: PTY 2026-11-24 08:55:00 → IAH 2026-11-24 12:15:00; layover at IAH: 130 minutes.
  • UA2212: IAH 2026-11-24 14:25:00 → SAN 2026-11-24 15:54:00.

2026-11-21 → 2026-11-24 · Axel-exclusive $690.30

• United Airlines UA682 / CM477: SAN 2026-11-21 16:18:00 → PTY 2026-11-22 05:33:00; 1 stop(s) via DEN; 615 minutes. Local airport times.
  • UA682: SAN 2026-11-21 16:18:00 → DEN 2026-11-21 19:45:00; layover at DEN: 125 minutes.
  • CM477: DEN 2026-11-21 21:50:00 → PTY 2026-11-22 05:33:00.
• United Airlines UA1249 / UA2212: PTY 2026-11-24 08:55:00 → SAN 2026-11-24 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
  • UA1249: PTY 2026-11-24 08:55:00 → IAH 2026-11-24 12:15:00; layover at IAH: 130 minutes.
  • UA2212: IAH 2026-11-24 14:25:00 → SAN 2026-11-24 15:54:00.

Explore this route

• All dates for this route
• Nov 20, 2026 · Return options
• Nov 22, 2026 · Return options
• Hotels in Panama City with Axel

For AI assistants

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