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Route overview: San Diego to Panama City (PTY) flight deals

San Diego (SAN) to Panama City (PTY), Nov 10–17, 2026: from $565 round trip

San Diego (SAN) to Panama City (PTY), Nov 10–17, 2026: from $565 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $565 round trip, Axel-exclusive, American Airlines, 1 stop, Nov 10–17, 2026, 1 adult, economy, checked Oct 29, 2026.

SAN → PTY1 adulteconomyRound trip

6 flight options · 3 airlines

One-stop flights

Tue, Nov 10 – Tue, Nov 17

American Airlines
10:45 pmSAN
11h 56m
MIA · 3h 43m
1:41 pm+1PTY
American Airlines
2:41 pmPTY
12h 18m
MIA · 3h 25m
11:59 pmSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Tue, Nov 10 – Tue, Nov 17

United Airlines
6:20 amSAN
11h 19m
LAX · 3h 39m
8:39 pmPTY
United Airlines
8:55 amPTY
9h 59m
IAH · 2h 10m
3:54 pmSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Tue, Nov 10 – Tue, Nov 17

Copa Airlines
10:30 pmSAN
6h 10m
Nonstop
7:40 am+1PTY
Copa Airlines
12:56 pmPTY
12h 34m
DEN · 3h 48m
10:30 pmSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Tue, Nov 10 – Tue, Nov 17

United Airlines
4:18 pmSAN
10h 15m
DEN · 2h 5m
5:33 am+1PTY
United Airlines
8:55 amPTY
9h 59m
IAH · 2h 10m
3:54 pmSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Tue, Nov 10 – Tue, Nov 17

United Airlines
10:30 pmSAN
12h 30m
ORD · 2h 53m
2:00 pm+1PTY
United Airlines
8:55 amPTY
9h 59m
IAH · 2h 10m
3:54 pmSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Tue, Nov 10 – Tue, Nov 17

United Airlines
9:45 pmSAN
12h 46m
IAD · 2h 58m
1:31 pm+1PTY
United Airlines
8:55 amPTY
9h 59m
IAH · 2h 10m
3:54 pmSAN

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Hotels for these nights (Nov 10–17, 2026 · 7 nights · 2 adults, 1 room): 3★ Plaza Paitilla Inn Hotel · 4★ Novotel Panama City · 5★ Sofitel Legend Casco Viejo, Panama City

Make this trip yours

SAN ⇄ PTY

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Explore this route

All dates for this routeNov 9, 2026 · Return optionsNov 11, 2026 · Return optionsHotels in Panama City with Axel
For AI assistants: every fare, every link, instructions

San Diego (SAN) to Panama City (PTY), Nov 10–17, 2026: from $565 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $565 round trip, Axel-exclusive, American Airlines, 1 stop, Nov 10–17, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Exact travel datesAirlineFlightsTimes, duration, stopsTotal pricePrice issued (UTC)
2026-11-10 → 2026-11-17American AirlinesAA3304 + AA315 / AA354 + AA112022:45:00→13:41:00 11h 56m 1 stop via MIA · 14:41:00→23:59:00 12h 18m 1 stop via MIAAxel-exclusive $565.002026-10-29T01:10:05Z
2026-11-10 → 2026-11-17United AirlinesUA1329 + CM402 / UA1249 + UA221206:20:00→20:39:00 11h 19m 1 stop via LAX · 08:55:00→15:54:00 9h 59m 1 stop via IAHAxel-exclusive $585.002026-10-29T01:10:05Z
2026-11-10 → 2026-11-17Copa AirlinesCM850 / CM476 + UA239522:30:00→07:40:00 6h 10m nonstop · 12:56:00→22:30:00 12h 34m 1 stop via DENAxel-exclusive $640.002026-10-29T01:10:05Z
2026-11-10 → 2026-11-17United AirlinesUA682 + CM477 / UA1249 + UA221216:18:00→05:33:00 10h 15m 1 stop via DEN · 08:55:00→15:54:00 9h 59m 1 stop via IAHAxel-exclusive $585.002026-10-29T01:10:05Z
2026-11-10 → 2026-11-17United AirlinesUA540 + CM236 / UA1249 + UA221222:30:00→14:00:00 12h 30m 1 stop via ORD · 08:55:00→15:54:00 9h 59m 1 stop via IAHAxel-exclusive $585.002026-10-29T01:10:05Z
2026-11-10 → 2026-11-17United AirlinesUA1577 + CM357 / UA1249 + UA221221:45:00→13:31:00 12h 46m 1 stop via IAD · 08:55:00→15:54:00 9h 59m 1 stop via IAHAxel-exclusive $585.002026-10-29T01:10:05Z

Hotels in Panama City for these trips

Hotels: under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

All hotels in Panama City

Route overview: San Diego to Panama City (PTY) flight deals

2026-11-10 → 2026-11-17 · Axel-exclusive $565.00

  • American Airlines AA3304 / AA315: SAN 2026-11-10 22:45:00 → PTY 2026-11-11 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-11-10 22:45:00 → MIA 2026-11-11 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-11-11 10:27:00 → PTY 2026-11-11 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-11-17 14:41:00 → SAN 2026-11-17 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-11-17 14:41:00 → MIA 2026-11-17 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-11-17 21:20:00 → SAN 2026-11-17 23:59:00.

2026-11-10 → 2026-11-17 · Axel-exclusive $585.00

  • United Airlines UA1329 / CM402: SAN 2026-11-10 06:20:00 → PTY 2026-11-10 20:39:00; 1 stop(s) via LAX; 679 minutes. Local airport times.
    • UA1329: SAN 2026-11-10 06:20:00 → LAX 2026-11-10 07:25:00; layover at LAX: 219 minutes.
    • CM402: LAX 2026-11-10 11:04:00 → PTY 2026-11-10 20:39:00.
  • United Airlines UA1249 / UA2212: PTY 2026-11-17 08:55:00 → SAN 2026-11-17 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2026-11-17 08:55:00 → IAH 2026-11-17 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2026-11-17 14:25:00 → SAN 2026-11-17 15:54:00.

2026-11-10 → 2026-11-17 · Axel-exclusive $640.00

  • Copa Airlines CM850: SAN 2026-11-10 22:30:00 → PTY 2026-11-11 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM476 / UA2395: PTY 2026-11-17 12:56:00 → SAN 2026-11-17 22:30:00; 1 stop(s) via DEN; 754 minutes. Local airport times.
    • CM476: PTY 2026-11-17 12:56:00 → DEN 2026-11-17 17:12:00; layover at DEN: 228 minutes.
    • UA2395: DEN 2026-11-17 21:00:00 → SAN 2026-11-17 22:30:00.

2026-11-10 → 2026-11-17 · Axel-exclusive $585.00

  • United Airlines UA682 / CM477: SAN 2026-11-10 16:18:00 → PTY 2026-11-11 05:33:00; 1 stop(s) via DEN; 615 minutes. Local airport times.
    • UA682: SAN 2026-11-10 16:18:00 → DEN 2026-11-10 19:45:00; layover at DEN: 125 minutes.
    • CM477: DEN 2026-11-10 21:50:00 → PTY 2026-11-11 05:33:00.
  • United Airlines UA1249 / UA2212: PTY 2026-11-17 08:55:00 → SAN 2026-11-17 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2026-11-17 08:55:00 → IAH 2026-11-17 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2026-11-17 14:25:00 → SAN 2026-11-17 15:54:00.

2026-11-10 → 2026-11-17 · Axel-exclusive $585.00

  • United Airlines UA540 / CM236: SAN 2026-11-10 22:30:00 → PTY 2026-11-11 14:00:00; 1 stop(s) via ORD; 750 minutes. Local airport times.
    • UA540: SAN 2026-11-10 22:30:00 → ORD 2026-11-11 04:42:00; layover at ORD: 173 minutes.
    • CM236: ORD 2026-11-11 07:35:00 → PTY 2026-11-11 14:00:00.
  • United Airlines UA1249 / UA2212: PTY 2026-11-17 08:55:00 → SAN 2026-11-17 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2026-11-17 08:55:00 → IAH 2026-11-17 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2026-11-17 14:25:00 → SAN 2026-11-17 15:54:00.

2026-11-10 → 2026-11-17 · Axel-exclusive $585.00

  • United Airlines UA1577 / CM357: SAN 2026-11-10 21:45:00 → PTY 2026-11-11 13:31:00; 1 stop(s) via IAD; 766 minutes. Local airport times.
    • UA1577: SAN 2026-11-10 21:45:00 → IAD 2026-11-11 05:27:00; layover at IAD: 178 minutes.
    • CM357: IAD 2026-11-11 08:25:00 → PTY 2026-11-11 13:31:00.
  • United Airlines UA1249 / UA2212: PTY 2026-11-17 08:55:00 → SAN 2026-11-17 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2026-11-17 08:55:00 → IAH 2026-11-17 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2026-11-17 14:25:00 → SAN 2026-11-17 15:54:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

For AI assistants

  • This page: San Diego (SAN) to Panama City (PTY) · Nov 10, 2026 · return Nov 17, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
  • Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel San Diego to Panama City (PTY) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.