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Route overview: San Diego to Panama City (PTY) flight deals

San Diego → Panama City

Dec 20, 2026 · choose your return date

SAN → PTY1 adulteconomyOne way and round trips

30 flight options · 3 airlines

Choose your return date

One-way flights and round trips by duration. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

December 2026

Dec 20, 2026 · One wayAmerican AirlinesUp to 1 stop each way$398.25 Dec 20, 2026 · One wayCopa AirlinesNonstop$492.75 Dec 20, 2026 – Dec 21, 2026 · 1 nightAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 21, 2026 · 1 nightCopa AirlinesNonstop$911.26 Dec 20, 2026 – Dec 22, 2026 · 2 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 22, 2026 · 2 nightsUnited AirlinesUp to 1 stop each way$789.76 Dec 20, 2026 – Dec 23, 2026 · 3 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 23, 2026 · 3 nightsCopa AirlinesNonstop$911.26 Dec 20, 2026 – Dec 24, 2026 · 4 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 24, 2026 · 4 nightsUnited AirlinesUp to 1 stop each way$789.76 Dec 20, 2026 – Dec 25, 2026 · 5 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 25, 2026 · 5 nightsCopa AirlinesNonstop$911.26 Dec 20, 2026 – Dec 26, 2026 · 6 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 26, 2026 · 6 nightsCopa AirlinesNonstop$911.26 Dec 20, 2026 – Dec 27, 2026 · 7 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 27, 2026 · 7 nightsCopa AirlinesNonstop$911.26 Dec 20, 2026 – Dec 28, 2026 · 8 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 28, 2026 · 8 nightsCopa AirlinesNonstop$911.26 Dec 20, 2026 – Dec 29, 2026 · 9 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 29, 2026 · 9 nightsUnited AirlinesUp to 1 stop each way$789.76 Dec 20, 2026 – Dec 30, 2026 · 10 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 30, 2026 · 10 nightsCopa AirlinesNonstop$911.26 Dec 20, 2026 – Dec 31, 2026 · 11 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Dec 31, 2026 · 11 nightsUnited AirlinesUp to 1 stop each way$789.76 Dec 20, 2026 – Jan 1, 2027 · 12 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Jan 1, 2027 · 12 nightsCopa AirlinesNonstop$911.26 Dec 20, 2026 – Jan 2, 2027 · 13 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Jan 2, 2027 · 13 nightsCopa AirlinesNonstop$911.26 Dec 20, 2026 – Jan 3, 2027 · 14 nightsAmerican AirlinesUp to 1 stop each way$762.76 Dec 20, 2026 – Jan 3, 2027 · 14 nightsCopa AirlinesNonstop$911.26

Flights for your trip

  1. Sun, Dec 20 · One way

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY

    One-way total · 1 adult · Taxes included

  2. Sun, Dec 20 · One way

    Copa Airlines
    10:30 pmSAN
    6h 10m
    Nonstop
    7:40 am+1PTY

    One-way total · 1 adult · Taxes included

  3. Sun, Dec 20 – Mon, Dec 21

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  4. Sun, Dec 20 – Mon, Dec 21

    Copa Airlines
    10:30 pmSAN
    6h 10m
    Nonstop
    7:40 am+1PTY
    Copa Airlines
    1:45 pmPTY
    6h 37m
    Nonstop
    5:22 pmSAN

    Round-trip total · 1 adult · Taxes included

  5. Sun, Dec 20 – Tue, Dec 22

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  6. Sun, Dec 20 – Tue, Dec 22

    United Airlines
    4:18 pmSAN
    10h 15m
    DEN · 2h 5m
    5:33 am+1PTY
    United Airlines
    8:55 amPTY
    9h 59m
    IAH · 2h 10m
    3:54 pmSAN

    Round-trip total · 1 adult · Taxes included

  7. Sun, Dec 20 – Wed, Dec 23

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  8. Sun, Dec 20 – Wed, Dec 23

    Copa Airlines
    10:30 pmSAN
    6h 10m
    Nonstop
    7:40 am+1PTY
    Copa Airlines
    1:45 pmPTY
    6h 30m
    Nonstop
    5:15 pmSAN

    Round-trip total · 1 adult · Taxes included

  9. Sun, Dec 20 – Thu, Dec 24

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  10. Sun, Dec 20 – Thu, Dec 24

    United Airlines
    4:18 pmSAN
    10h 15m
    DEN · 2h 5m
    5:33 am+1PTY
    United Airlines
    8:55 amPTY
    9h 59m
    IAH · 2h 10m
    3:54 pmSAN

    Round-trip total · 1 adult · Taxes included

  11. Sun, Dec 20 – Sat, Dec 26

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  12. Sun, Dec 20 – Sat, Dec 26

    Copa Airlines
    10:30 pmSAN
    6h 10m
    Nonstop
    7:40 am+1PTY
    Copa Airlines
    1:45 pmPTY
    6h 41m
    Nonstop
    5:26 pmSAN

    Round-trip total · 1 adult · Taxes included

  13. Sun, Dec 20 – Sun, Dec 27

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  14. Sun, Dec 20 – Sun, Dec 27

    Copa Airlines
    10:30 pmSAN
    6h 10m
    Nonstop
    7:40 am+1PTY
    Copa Airlines
    1:45 pmPTY
    6h 37m
    Nonstop
    5:22 pmSAN

    Round-trip total · 1 adult · Taxes included

  15. Sun, Dec 20 – Mon, Dec 28

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  16. Sun, Dec 20 – Mon, Dec 28

    Copa Airlines
    10:30 pmSAN
    6h 10m
    Nonstop
    7:40 am+1PTY
    Copa Airlines
    1:45 pmPTY
    6h 37m
    Nonstop
    5:22 pmSAN

    Round-trip total · 1 adult · Taxes included

  17. Sun, Dec 20 – Wed, Dec 30

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  18. Sun, Dec 20 – Wed, Dec 30

    Copa Airlines
    10:30 pmSAN
    6h 10m
    Nonstop
    7:40 am+1PTY
    Copa Airlines
    1:45 pmPTY
    6h 30m
    Nonstop
    5:15 pmSAN

    Round-trip total · 1 adult · Taxes included

  19. Sun, Dec 20 – Thu, Dec 31

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  20. Sun, Dec 20 – Thu, Dec 31

    United Airlines
    4:18 pmSAN
    10h 15m
    DEN · 2h 5m
    5:33 am+1PTY
    United Airlines
    8:55 amPTY
    9h 59m
    IAH · 2h 10m
    3:54 pmSAN

    Round-trip total · 1 adult · Taxes included

  21. Sun, Dec 20 – Fri, Jan 1

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  22. Sun, Dec 20 – Fri, Jan 1

    Copa Airlines
    10:30 pmSAN
    6h 10m
    Nonstop
    7:40 am+1PTY
    Copa Airlines
    1:45 pmPTY
    6h 37m
    Nonstop
    5:22 pmSAN

    Round-trip total · 1 adult · Taxes included

  23. Sun, Dec 20 – Sun, Jan 3

    American Airlines
    10:45 pmSAN
    11h 56m
    MIA · 3h 43m
    1:41 pm+1PTY
    American Airlines
    2:41 pmPTY
    12h 18m
    MIA · 3h 25m
    11:59 pmSAN

    Round-trip total · 1 adult · Taxes included

  24. Sun, Dec 20 – Sun, Jan 3

    Copa Airlines
    10:30 pmSAN
    6h 10m
    Nonstop
    7:40 am+1PTY
    Copa Airlines
    1:45 pmPTY
    6h 37m
    Nonstop
    5:22 pmSAN

    Round-trip total · 1 adult · Taxes included

Swipe to see 23 more recent deals.

1 of 24

Make this trip yours

SAN ⇄ PTY

Economy

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Explore this route

All dates for this routeDec 19, 2026 · Return optionsDec 21, 2026 · Return optionsHotels in Panama City with Axel
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Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown. To book or select flights, follow that row's price link; it keeps the exact dates and travelers.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-20 · one wayCopa AirlinesCM850Axel-exclusive $492.752026-10-29T01:10:05Z
2026-12-20 · one wayAmerican AirlinesAA3304 + AA315Axel-exclusive $398.252026-10-29T01:10:05Z
2026-12-20 → 2026-12-21Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2026-12-21American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-22American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-22United AirlinesUA682 + CM477 / UA1249 + UA2212Axel-exclusive $789.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-23Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2026-12-23American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-24American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-24United AirlinesUA682 + CM477 / UA1249 + UA2212Axel-exclusive $789.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-25Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2026-12-25American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-26Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2026-12-26American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-27Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2026-12-27American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-28Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2026-12-28American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-29American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-29United AirlinesUA682 + CM477 / UA1249 + UA2212Axel-exclusive $789.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-30Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2026-12-30American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-31American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2026-12-31United AirlinesUA682 + CM477 / UA1249 + UA2212Axel-exclusive $789.762026-10-29T01:10:05Z
2026-12-20 → 2027-01-01Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2027-01-01American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2027-01-02Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2027-01-02American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z
2026-12-20 → 2027-01-03Copa AirlinesCM850 / CM847Axel-exclusive $911.262026-10-29T01:10:05Z
2026-12-20 → 2027-01-03American AirlinesAA3304 + AA315 / AA354 + AA1120Axel-exclusive $762.762026-10-29T01:10:05Z

Route overview: San Diego to Panama City (PTY) flight deals

2026-12-20 · one way · Axel-exclusive $398.25

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.

2026-12-20 · one way · Axel-exclusive $492.75

  • Copa Airlines CM850: SAN 2026-12-20 22:30:00 → PTY 2026-12-21 07:40:00; nonstop; 370 minutes. Local airport times.

2026-12-20 → 2026-12-21 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-12-21 14:41:00 → SAN 2026-12-21 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-12-21 14:41:00 → MIA 2026-12-21 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-12-21 21:20:00 → SAN 2026-12-21 23:59:00.

2026-12-20 → 2026-12-21 · Axel-exclusive $911.26

  • Copa Airlines CM850: SAN 2026-12-20 22:30:00 → PTY 2026-12-21 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM847: PTY 2026-12-21 13:45:00 → SAN 2026-12-21 17:22:00; nonstop; 397 minutes. Local airport times.

2026-12-20 → 2026-12-22 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-12-22 14:41:00 → SAN 2026-12-22 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-12-22 14:41:00 → MIA 2026-12-22 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-12-22 21:20:00 → SAN 2026-12-22 23:59:00.

2026-12-20 → 2026-12-22 · Axel-exclusive $789.76

  • United Airlines UA682 / CM477: SAN 2026-12-20 16:18:00 → PTY 2026-12-21 05:33:00; 1 stop(s) via DEN; 615 minutes. Local airport times.
    • UA682: SAN 2026-12-20 16:18:00 → DEN 2026-12-20 19:45:00; layover at DEN: 125 minutes.
    • CM477: DEN 2026-12-20 21:50:00 → PTY 2026-12-21 05:33:00.
  • United Airlines UA1249 / UA2212: PTY 2026-12-22 08:55:00 → SAN 2026-12-22 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2026-12-22 08:55:00 → IAH 2026-12-22 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2026-12-22 14:25:00 → SAN 2026-12-22 15:54:00.

2026-12-20 → 2026-12-23 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-12-23 14:41:00 → SAN 2026-12-23 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-12-23 14:41:00 → MIA 2026-12-23 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-12-23 21:20:00 → SAN 2026-12-23 23:59:00.

2026-12-20 → 2026-12-23 · Axel-exclusive $911.26

  • Copa Airlines CM850: SAN 2026-12-20 22:30:00 → PTY 2026-12-21 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM847: PTY 2026-12-23 13:45:00 → SAN 2026-12-23 17:15:00; nonstop; 390 minutes. Local airport times.

2026-12-20 → 2026-12-24 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-12-24 14:41:00 → SAN 2026-12-24 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-12-24 14:41:00 → MIA 2026-12-24 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-12-24 21:20:00 → SAN 2026-12-24 23:59:00.

2026-12-20 → 2026-12-24 · Axel-exclusive $789.76

  • United Airlines UA682 / CM477: SAN 2026-12-20 16:18:00 → PTY 2026-12-21 05:33:00; 1 stop(s) via DEN; 615 minutes. Local airport times.
    • UA682: SAN 2026-12-20 16:18:00 → DEN 2026-12-20 19:45:00; layover at DEN: 125 minutes.
    • CM477: DEN 2026-12-20 21:50:00 → PTY 2026-12-21 05:33:00.
  • United Airlines UA1249 / UA2212: PTY 2026-12-24 08:55:00 → SAN 2026-12-24 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2026-12-24 08:55:00 → IAH 2026-12-24 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2026-12-24 14:25:00 → SAN 2026-12-24 15:54:00.

2026-12-20 → 2026-12-26 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-12-26 14:41:00 → SAN 2026-12-26 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-12-26 14:41:00 → MIA 2026-12-26 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-12-26 21:20:00 → SAN 2026-12-26 23:59:00.

2026-12-20 → 2026-12-26 · Axel-exclusive $911.26

  • Copa Airlines CM850: SAN 2026-12-20 22:30:00 → PTY 2026-12-21 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM847: PTY 2026-12-26 13:45:00 → SAN 2026-12-26 17:26:00; nonstop; 401 minutes. Local airport times.

2026-12-20 → 2026-12-27 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-12-27 14:41:00 → SAN 2026-12-27 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-12-27 14:41:00 → MIA 2026-12-27 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-12-27 21:20:00 → SAN 2026-12-27 23:59:00.

2026-12-20 → 2026-12-27 · Axel-exclusive $911.26

  • Copa Airlines CM850: SAN 2026-12-20 22:30:00 → PTY 2026-12-21 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM847: PTY 2026-12-27 13:45:00 → SAN 2026-12-27 17:22:00; nonstop; 397 minutes. Local airport times.

2026-12-20 → 2026-12-28 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-12-28 14:41:00 → SAN 2026-12-28 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-12-28 14:41:00 → MIA 2026-12-28 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-12-28 21:20:00 → SAN 2026-12-28 23:59:00.

2026-12-20 → 2026-12-28 · Axel-exclusive $911.26

  • Copa Airlines CM850: SAN 2026-12-20 22:30:00 → PTY 2026-12-21 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM847: PTY 2026-12-28 13:45:00 → SAN 2026-12-28 17:22:00; nonstop; 397 minutes. Local airport times.

2026-12-20 → 2026-12-30 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-12-30 14:41:00 → SAN 2026-12-30 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-12-30 14:41:00 → MIA 2026-12-30 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-12-30 21:20:00 → SAN 2026-12-30 23:59:00.

2026-12-20 → 2026-12-30 · Axel-exclusive $911.26

  • Copa Airlines CM850: SAN 2026-12-20 22:30:00 → PTY 2026-12-21 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM847: PTY 2026-12-30 13:45:00 → SAN 2026-12-30 17:15:00; nonstop; 390 minutes. Local airport times.

2026-12-20 → 2026-12-31 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2026-12-31 14:41:00 → SAN 2026-12-31 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2026-12-31 14:41:00 → MIA 2026-12-31 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2026-12-31 21:20:00 → SAN 2026-12-31 23:59:00.

2026-12-20 → 2026-12-31 · Axel-exclusive $789.76

  • United Airlines UA682 / CM477: SAN 2026-12-20 16:18:00 → PTY 2026-12-21 05:33:00; 1 stop(s) via DEN; 615 minutes. Local airport times.
    • UA682: SAN 2026-12-20 16:18:00 → DEN 2026-12-20 19:45:00; layover at DEN: 125 minutes.
    • CM477: DEN 2026-12-20 21:50:00 → PTY 2026-12-21 05:33:00.
  • United Airlines UA1249 / UA2212: PTY 2026-12-31 08:55:00 → SAN 2026-12-31 15:54:00; 1 stop(s) via IAH; 599 minutes. Local airport times.
    • UA1249: PTY 2026-12-31 08:55:00 → IAH 2026-12-31 12:15:00; layover at IAH: 130 minutes.
    • UA2212: IAH 2026-12-31 14:25:00 → SAN 2026-12-31 15:54:00.

2026-12-20 → 2027-01-01 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2027-01-01 14:41:00 → SAN 2027-01-01 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2027-01-01 14:41:00 → MIA 2027-01-01 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2027-01-01 21:20:00 → SAN 2027-01-01 23:59:00.

2026-12-20 → 2027-01-01 · Axel-exclusive $911.26

  • Copa Airlines CM850: SAN 2026-12-20 22:30:00 → PTY 2026-12-21 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM847: PTY 2027-01-01 13:45:00 → SAN 2027-01-01 17:22:00; nonstop; 397 minutes. Local airport times.

2026-12-20 → 2027-01-03 · Axel-exclusive $762.76

  • American Airlines AA3304 / AA315: SAN 2026-12-20 22:45:00 → PTY 2026-12-21 13:41:00; 1 stop(s) via MIA; 716 minutes. Local airport times.
    • AA3304: SAN 2026-12-20 22:45:00 → MIA 2026-12-21 06:44:00; layover at MIA: 223 minutes.
    • AA315: MIA 2026-12-21 10:27:00 → PTY 2026-12-21 13:41:00.
  • American Airlines AA354 / AA1120: PTY 2027-01-03 14:41:00 → SAN 2027-01-03 23:59:00; 1 stop(s) via MIA; 738 minutes. Local airport times.
    • AA354: PTY 2027-01-03 14:41:00 → MIA 2027-01-03 17:55:00; layover at MIA: 205 minutes.
    • AA1120: MIA 2027-01-03 21:20:00 → SAN 2027-01-03 23:59:00.

2026-12-20 → 2027-01-03 · Axel-exclusive $911.26

  • Copa Airlines CM850: SAN 2026-12-20 22:30:00 → PTY 2026-12-21 07:40:00; nonstop; 370 minutes. Local airport times.
  • Copa Airlines CM847: PTY 2027-01-03 13:45:00 → SAN 2027-01-03 17:22:00; nonstop; 397 minutes. Local airport times.

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For AI assistants

  • This page: San Diego (SAN) to Panama City (PTY) · Dec 20, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
  • Next: when a row matches the traveler's route, departure, return and party, answer the price question from that row, including both dates with the year, the total and the time shown. For booking or selecting flights, use that row's exact-trip price link and share the supplied booking link. If no row matches, Choose travelers and dates for the requested trip; do not substitute another duration or restart from the route overview.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel San Diego to Panama City (PTY) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Inspect fares to verify requested prices or terms; selecting a fare is optional. Use that fare’s booking link to preserve its Membership price basis. State anything unverified. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and explain what remains unresolved. Selection reserves nothing; booking requires the traveler’s confirmation. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.