Travel with Axel,
get the best price.

Route overview: San Diego to Boston (BOS) flight deals

San Diego → Boston

Nov 21, 2026 · one way

SAN → BOS1 adulteconomyOne way

13 flight options · 5 airlines

Nonstop flights

Sat, Nov 21 · One way

JetBlue Airways
8:55 pmSAN
5h 30m
Nonstop
5:25 am+1BOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

Southwest Airlines
10:30 pmSAN
5h 15m
Nonstop
6:45 am+1BOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

Alaska Airlines
8:46 pmSAN
5h 42m
Nonstop
5:28 am+1BOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

Delta Air Lines
10:17 pmSAN
5h 23m
Nonstop
6:40 am+1BOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

JetBlue Airways
11:44 amSAN
5h 32m
Nonstop
8:16 pmBOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

Southwest Airlines
9:35 amSAN
5h 25m
Nonstop
6:00 pmBOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

Alaska Airlines
8:32 amSAN
5h 36m
Nonstop
5:08 pmBOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

One-stop flights

Sat, Nov 21 · One way

American Airlines
1:05 pmSAN
7h 41m
PHX · 1h 15m
11:46 pmBOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

Southwest Airlines
9:55 pmSAN
7h 25m
BWI · 1h 10m
8:20 am+1BOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

Southwest Airlines
11:55 amSAN
7h 20m
BNA · 1h
10:15 pmBOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

Alaska Airlines
10:03 pmSAN
8h 2m
JFK · 1h 12m
9:05 am+1BOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

American Airlines
10:45 pmSAN
7h 48m
ORD · 1h 11m
9:33 am+1BOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 21 · One way

Delta Air Lines
10:35 pmSAN
7h 28m
DTW · 1h 4m
9:03 am+1BOS

One-way total · 1 adult · Taxes included

Availability is checked when you select these flights.

Make this trip yours

SAN ⇄ BOS

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

No account needed to see prices.

Already have an account? Log in

Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, JetBlue Airways emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • Not satisfied? Full refund.If you are unhappy with the experience for any reason, or simply change your mind, cancel within 24 hours of booking (departure 7+ days away) and we refund you in full. We stand by our product. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

Explore this route

For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-21 · one wayJetBlue AirwaysB62120Axel-exclusive $280.002026-10-29T01:08:43Z
2026-11-21 · one waySouthwest AirlinesWN280Axel-exclusive $287.002026-10-29T01:08:43Z
2026-11-21 · one wayAlaska AirlinesAS255Axel-exclusive $294.002026-10-29T01:08:43Z
2026-11-21 · one wayDelta Air LinesDL571Axel-exclusive $315.002026-10-29T01:08:43Z
2026-11-21 · one wayAmerican AirlinesAA1813 + AA1422Axel-exclusive $266.002026-10-29T01:08:43Z
2026-11-21 · one wayJetBlue AirwaysB6920Axel-exclusive $280.002026-10-29T01:08:43Z
2026-11-21 · one waySouthwest AirlinesWN4672Axel-exclusive $287.002026-10-29T01:08:43Z
2026-11-21 · one wayAlaska AirlinesAS390Axel-exclusive $294.002026-10-29T01:08:43Z
2026-11-21 · one waySouthwest AirlinesWN3691 + WN4725Axel-exclusive $252.002026-10-29T01:08:43Z
2026-11-21 · one waySouthwest AirlinesWN4669 + WN2217Axel-exclusive $252.002026-10-29T01:08:43Z
2026-11-21 · one wayAlaska AirlinesAS36 + AA4357Axel-exclusive $259.002026-10-29T01:08:43Z
2026-11-21 · one wayAmerican AirlinesAA1494 + AA640Axel-exclusive $266.002026-10-29T01:08:43Z
2026-11-21 · one wayDelta Air LinesDL764 + DL1163Axel-exclusive $280.002026-10-29T01:08:43Z

Route overview: San Diego to Boston (BOS) flight deals

2026-11-21 · one way · Axel-exclusive $280.00

  • JetBlue Airways B62120: SAN 2026-11-21 20:55:00 → BOS 2026-11-22 05:25:00; nonstop; 330 minutes. Local airport times.

2026-11-21 · one way · Axel-exclusive $287.00

  • Southwest Airlines WN280: SAN 2026-11-21 22:30:00 → BOS 2026-11-22 06:45:00; nonstop; 315 minutes. Local airport times.

2026-11-21 · one way · Axel-exclusive $294.00

  • Alaska Airlines AS255: SAN 2026-11-21 20:46:00 → BOS 2026-11-22 05:28:00; nonstop; 342 minutes. Local airport times.

2026-11-21 · one way · Axel-exclusive $315.00

  • Delta Air Lines DL571: SAN 2026-11-21 22:17:00 → BOS 2026-11-22 06:40:00; nonstop; 323 minutes. Local airport times.

2026-11-21 · one way · Axel-exclusive $266.00

  • American Airlines AA1813 / AA1422: SAN 2026-11-21 13:05:00 → BOS 2026-11-21 23:46:00; 1 stop(s) via PHX; 461 minutes. Local airport times.
    • AA1813: SAN 2026-11-21 13:05:00 → PHX 2026-11-21 15:37:00; layover at PHX: 75 minutes.
    • AA1422: PHX 2026-11-21 16:52:00 → BOS 2026-11-21 23:46:00.

2026-11-21 · one way · Axel-exclusive $280.00

  • JetBlue Airways B6920: SAN 2026-11-21 11:44:00 → BOS 2026-11-21 20:16:00; nonstop; 332 minutes. Local airport times.

2026-11-21 · one way · Axel-exclusive $287.00

  • Southwest Airlines WN4672: SAN 2026-11-21 09:35:00 → BOS 2026-11-21 18:00:00; nonstop; 325 minutes. Local airport times.

2026-11-21 · one way · Axel-exclusive $294.00

  • Alaska Airlines AS390: SAN 2026-11-21 08:32:00 → BOS 2026-11-21 17:08:00; nonstop; 336 minutes. Local airport times.

2026-11-21 · one way · Axel-exclusive $252.00

  • Southwest Airlines WN3691 / WN4725: SAN 2026-11-21 21:55:00 → BOS 2026-11-22 08:20:00; 1 stop(s) via BWI; 445 minutes. Local airport times.
    • WN3691: SAN 2026-11-21 21:55:00 → BWI 2026-11-22 05:35:00; layover at BWI: 70 minutes.
    • WN4725: BWI 2026-11-22 06:45:00 → BOS 2026-11-22 08:20:00.

2026-11-21 · one way · Axel-exclusive $252.00

  • Southwest Airlines WN4669 / WN2217: SAN 2026-11-21 11:55:00 → BOS 2026-11-21 22:15:00; 1 stop(s) via BNA; 440 minutes. Local airport times.
    • WN4669: SAN 2026-11-21 11:55:00 → BNA 2026-11-21 17:45:00; layover at BNA: 60 minutes.
    • WN2217: BNA 2026-11-21 18:45:00 → BOS 2026-11-21 22:15:00.

2026-11-21 · one way · Axel-exclusive $259.00

  • Alaska Airlines AS36 / AA4357: SAN 2026-11-21 22:03:00 → BOS 2026-11-22 09:05:00; 1 stop(s) via JFK; 482 minutes. Local airport times.
    • AS36: SAN 2026-11-21 22:03:00 → JFK 2026-11-22 06:29:00; layover at JFK: 72 minutes.
    • AA4357: JFK 2026-11-22 07:41:00 → BOS 2026-11-22 09:05:00.

2026-11-21 · one way · Axel-exclusive $266.00

  • American Airlines AA1494 / AA640: SAN 2026-11-21 22:45:00 → BOS 2026-11-22 09:33:00; 1 stop(s) via ORD; 468 minutes. Local airport times.
    • AA1494: SAN 2026-11-21 22:45:00 → ORD 2026-11-22 04:49:00; layover at ORD: 71 minutes.
    • AA640: ORD 2026-11-22 06:00:00 → BOS 2026-11-22 09:33:00.

2026-11-21 · one way · Axel-exclusive $280.00

  • Delta Air Lines DL764 / DL1163: SAN 2026-11-21 22:35:00 → BOS 2026-11-22 09:03:00; 1 stop(s) via DTW; 448 minutes. Local airport times.
    • DL764: SAN 2026-11-21 22:35:00 → DTW 2026-11-22 05:56:00; layover at DTW: 64 minutes.
    • DL1163: DTW 2026-11-22 07:00:00 → BOS 2026-11-22 09:03:00.

Explore this route

For AI assistants

  • This page: San Diego (SAN) to Boston (BOS) · Nov 21, 2026 · one way: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
  • Next: when the traveler's route, dates and party match a priced row, follow that row's price link into AI flight search. Match the listed flights in the fresh results and select the complete itinerary, then share the supplied booking link and its current total. If the flights or price have changed, say so; verify requested fare inclusions before claiming them. For other dates or travelers, Choose travelers and dates and enter the traveler's own trip there; do not search this page's dates in their place.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel San Diego to Boston (BOS) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.