Fort Myers (RSW) to San Francisco (SFO), Nov 17–21, 2026: from $443 round trip

Fort Myers (RSW) to San Francisco (SFO), Nov 17–21, 2026: from $443 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $443 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 17–21, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in San Francisco for these nights (Nov 17–21, 2026 · 4 nights · 2 adults, 1 room): 3★ Hotel Del Sol, $1,365 total · 4★ BEI Hotel San Francisco, $1,634 total · 5★ Palace Hotel, a Luxury Collection Hotel, San Francisco, $3,240 total

All hotels in San Francisco

Route overview: Fort Myers to San Francisco (SFO) flight deals

2026-11-17 → 2026-11-21 · Axel-exclusive $442.75

• Southwest Airlines WN3929 / WN4813: RSW 2026-11-17 16:50:00 → SFO 2026-11-17 23:00:00; 1 stop(s) via BNA; 550 minutes. Local airport times.
  • WN3929: RSW 2026-11-17 16:50:00 → BNA 2026-11-17 18:00:00; layover at BNA: 115 minutes.
  • WN4813: BNA 2026-11-17 19:55:00 → SFO 2026-11-17 23:00:00.
• Southwest Airlines WN1262 / WN222: SFO 2026-11-21 22:45:00 → RSW 2026-11-22 09:15:00; 1 stop(s) via BNA; 450 minutes. Local airport times.
  • WN1262: SFO 2026-11-21 22:45:00 → BNA 2026-11-22 05:05:00; layover at BNA: 70 minutes.
  • WN222: BNA 2026-11-22 06:15:00 → RSW 2026-11-22 09:15:00.

2026-11-17 → 2026-11-21 · Axel-exclusive $460.00

• American Airlines AA1637 / AA2427: RSW 2026-11-17 17:25:00 → SFO 2026-11-17 22:54:00; 1 stop(s) via PHX; 509 minutes. Local airport times.
  • AA1637: RSW 2026-11-17 17:25:00 → PHX 2026-11-17 20:16:00; layover at PHX: 81 minutes.
  • AA2427: PHX 2026-11-17 21:37:00 → SFO 2026-11-17 22:54:00.
• American Airlines AA901 / AA2826: SFO 2026-11-21 18:51:00 → RSW 2026-11-22 05:00:00; 1 stop(s) via PHX; 429 minutes. Local airport times.
  • AA901: SFO 2026-11-21 18:51:00 → PHX 2026-11-21 22:00:00; layover at PHX: 64 minutes.
  • AA2826: PHX 2026-11-21 23:04:00 → RSW 2026-11-22 05:00:00.

2026-11-17 → 2026-11-21 · Axel-exclusive $465.25

• Delta Air Lines DL2400 / DL2809: RSW 2026-11-17 14:45:00 → SFO 2026-11-17 20:49:00; 1 stop(s) via MSP; 544 minutes. Local airport times.
  • DL2400: RSW 2026-11-17 14:45:00 → MSP 2026-11-17 17:25:00; layover at MSP: 64 minutes.
  • DL2809: MSP 2026-11-17 18:29:00 → SFO 2026-11-17 20:49:00.
• Southwest Airlines WN1262 / WN222: SFO 2026-11-21 22:45:00 → RSW 2026-11-22 09:15:00; 1 stop(s) via BNA; 450 minutes. Local airport times.
  • WN1262: SFO 2026-11-21 22:45:00 → BNA 2026-11-22 05:05:00; layover at BNA: 70 minutes.
  • WN222: BNA 2026-11-22 06:15:00 → RSW 2026-11-22 09:15:00.

2026-11-17 → 2026-11-21 · Axel-exclusive $471.50

• United Airlines UA676 / UA1535: RSW 2026-11-17 14:29:00 → SFO 2026-11-17 20:10:00; 1 stop(s) via IAH; 521 minutes. Local airport times.
  • UA676: RSW 2026-11-17 14:29:00 → IAH 2026-11-17 16:17:00; layover at IAH: 88 minutes.
  • UA1535: IAH 2026-11-17 17:45:00 → SFO 2026-11-17 20:10:00.
• United Airlines UA2117 / UA2628: SFO 2026-11-21 19:52:00 → RSW 2026-11-22 06:19:00; 1 stop(s) via DEN; 447 minutes. Local airport times.
  • UA2117: SFO 2026-11-21 19:52:00 → DEN 2026-11-21 23:30:00; layover at DEN: 71 minutes.
  • UA2628: DEN 2026-11-22 00:41:00 → RSW 2026-11-22 06:19:00.

2026-11-17 → 2026-11-21 · Axel-exclusive $471.50

• United Airlines UA1300 / UA1389: RSW 2026-11-17 15:52:00 → SFO 2026-11-17 21:10:00; 1 stop(s) via DEN; 498 minutes. Local airport times.
  • UA1300: RSW 2026-11-17 15:52:00 → DEN 2026-11-17 18:16:00; layover at DEN: 64 minutes.
  • UA1389: DEN 2026-11-17 19:20:00 → SFO 2026-11-17 21:10:00.
• United Airlines UA2117 / UA2628: SFO 2026-11-21 19:52:00 → RSW 2026-11-22 06:19:00; 1 stop(s) via DEN; 447 minutes. Local airport times.
  • UA2117: SFO 2026-11-21 19:52:00 → DEN 2026-11-21 23:30:00; layover at DEN: 71 minutes.
  • UA2628: DEN 2026-11-22 00:41:00 → RSW 2026-11-22 06:19:00.

2026-11-17 → 2026-11-21 · Axel-exclusive $496.50

• United Airlines UA433: RSW 2026-11-17 09:30:00 → SFO 2026-11-17 12:36:00; nonstop; 366 minutes. Local airport times.
• United Airlines UA2117 / UA2628: SFO 2026-11-21 19:52:00 → RSW 2026-11-22 06:19:00; 1 stop(s) via DEN; 447 minutes. Local airport times.
  • UA2117: SFO 2026-11-21 19:52:00 → DEN 2026-11-21 23:30:00; layover at DEN: 71 minutes.
  • UA2628: DEN 2026-11-22 00:41:00 → RSW 2026-11-22 06:19:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 16, 2026 · Return options
• Nov 18, 2026 · Return options
• Hotels in San Francisco with Axel

For AI assistants

• This page: Fort Myers (RSW) to San Francisco (SFO) · Nov 17, 2026 · return Nov 21, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
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