Fort Myers (RSW) to San Francisco (SFO), Dec 27, 2026: round trips from $452, one way from $270

Fort Myers (RSW) to San Francisco (SFO), Dec 27, 2026: round trips from $452, one way from $270 on Axel, checked Oct 29, 2026. Lowest published fares: $452 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Dec 27, 2026 – Jan 4, 2027; $270 one way, Axel-exclusive, Southwest Airlines, 1 stop, Dec 27, 2026; 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in San Francisco for these nights (Dec 27–28, 2026 · 1 night · 2 adults, 1 room): 3★ Tilden Hotel, $83 total · 4★ BEI Hotel San Francisco, $129 total · 5★ Taj Campton Place, $227 total
• Hotels in San Francisco for these nights (Dec 27–29, 2026 · 2 nights · 2 adults, 1 room): 3★ Tilden Hotel, $162 total · 4★ BEI Hotel San Francisco, $263 total · 5★ Taj Campton Place, $461 total
• Hotels in San Francisco for these nights (Dec 27–30, 2026 · 3 nights · 2 adults, 1 room): 3★ Tilden Hotel, $246 total · 4★ BEI Hotel San Francisco, $395 total · 5★ Taj Campton Place, $695 total
• Hotels in San Francisco for these nights (Dec 27–31, 2026 · 4 nights · 2 adults, 1 room): 3★ Tilden Hotel, $327 total · 4★ Hotel Bijou - Union Square, $529 total · 5★ Taj Campton Place, $929 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 1, 2027 · 5 nights · 2 adults, 1 room): 3★ Tilden Hotel, $437 total · 4★ Hotel Bijou - Union Square, $660 total · 5★ Taj Campton Place, $1,514 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 2, 2027 · 6 nights · 2 adults, 1 room): 3★ Tilden Hotel, $518 total · 4★ Hotel Bijou - Union Square, $794 total · 5★ Taj Campton Place, $1,849 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 3, 2027 · 7 nights · 2 adults, 1 room): 3★ Tilden Hotel, $602 total · 4★ Hotel Bijou - Union Square, $927 total · 5★ Taj Campton Place, $2,091 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 4, 2027 · 8 nights · 2 adults, 1 room): 3★ Tilden Hotel, $687 total · 4★ Hotel Bijou - Union Square, $1,061 total · 5★ Taj Campton Place, $2,314 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 5, 2027 · 9 nights · 2 adults, 1 room): 3★ Tilden Hotel, $771 total · 4★ Hotel Bijou - Union Square, $1,194 total · 5★ Taj Campton Place, $2,537 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 6, 2027 · 10 nights · 2 adults, 1 room): 3★ Tilden Hotel, $855 total · 4★ Hotel Bijou - Union Square, $1,328 total · 5★ Taj Campton Place, $2,760 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 7, 2027 · 11 nights · 2 adults, 1 room): 3★ Tilden Hotel, $938 total · 4★ Hotel Bijou - Union Square, $1,461 total · 5★ Taj Campton Place, $2,983 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 8, 2027 · 12 nights · 2 adults, 1 room): 3★ Tilden Hotel, $1,021 total · 4★ Hotel Bijou - Union Square, $1,595 total · 5★ Taj Campton Place, $3,206 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 9, 2027 · 13 nights · 2 adults, 1 room): 3★ Tilden Hotel, $1,130 total · 4★ Hotel Bijou - Union Square, $1,735 total · 5★ Taj Campton Place, $3,509 total
• Hotels in San Francisco for these nights (Dec 27 – Jan 10, 2027 · 14 nights · 2 adults, 1 room): 3★ Tilden Hotel, $1,245 total · 4★ Hotel Bijou - Union Square, $1,905 total · 5★ Taj Campton Place, $3,844 total

All hotels in San Francisco

Route overview: Fort Myers to San Francisco (SFO) flight deals

2026-12-27 · one way · Axel-exclusive $270.00

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.

2026-12-27 · one way · Axel-exclusive $324.00

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.

2026-12-27 → 2026-12-28 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2026-12-28 11:15:00 → RSW 2026-12-28 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2026-12-28 11:15:00 → STL 2026-12-28 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2026-12-28 18:20:00 → RSW 2026-12-28 21:50:00.

2026-12-27 → 2026-12-28 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2026-12-28 13:50:00 → RSW 2026-12-28 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-27 → 2026-12-29 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2026-12-29 11:15:00 → RSW 2026-12-29 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2026-12-29 11:15:00 → STL 2026-12-29 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2026-12-29 18:20:00 → RSW 2026-12-29 21:50:00.

2026-12-27 → 2026-12-29 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2026-12-29 13:50:00 → RSW 2026-12-29 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-27 → 2026-12-30 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN2331 / WN2097: SFO 2026-12-30 06:00:00 → RSW 2026-12-30 17:00:00; 1 stop(s) via MDW; 480 minutes. Local airport times.
  • WN2331: SFO 2026-12-30 06:00:00 → MDW 2026-12-30 12:15:00; layover at MDW: 60 minutes.
  • WN2097: MDW 2026-12-30 13:15:00 → RSW 2026-12-30 17:00:00.

2026-12-27 → 2026-12-30 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2026-12-30 13:50:00 → RSW 2026-12-30 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-27 → 2026-12-31 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2026-12-31 11:15:00 → RSW 2026-12-31 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2026-12-31 11:15:00 → STL 2026-12-31 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2026-12-31 18:20:00 → RSW 2026-12-31 21:50:00.

2026-12-27 → 2026-12-31 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2026-12-31 13:50:00 → RSW 2026-12-31 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-27 → 2027-01-02 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN1262 / WN222: SFO 2027-01-02 22:45:00 → RSW 2027-01-03 09:15:00; 1 stop(s) via BNA; 450 minutes. Local airport times.
  • WN1262: SFO 2027-01-02 22:45:00 → BNA 2027-01-03 05:05:00; layover at BNA: 70 minutes.
  • WN222: BNA 2027-01-03 06:15:00 → RSW 2027-01-03 09:15:00.

2026-12-27 → 2027-01-02 · Axel-exclusive $540.00

• American Airlines AA1637 / AA2427: RSW 2026-12-27 17:25:00 → SFO 2026-12-27 22:54:00; 1 stop(s) via PHX; 509 minutes. Local airport times.
  • AA1637: RSW 2026-12-27 17:25:00 → PHX 2026-12-27 20:16:00; layover at PHX: 81 minutes.
  • AA2427: PHX 2026-12-27 21:37:00 → SFO 2026-12-27 22:54:00.
• American Airlines AA901 / AA2826: SFO 2027-01-02 18:51:00 → RSW 2027-01-03 05:00:00; 1 stop(s) via PHX; 429 minutes. Local airport times.
  • AA901: SFO 2027-01-02 18:51:00 → PHX 2027-01-02 22:00:00; layover at PHX: 64 minutes.
  • AA2826: PHX 2027-01-02 23:04:00 → RSW 2027-01-03 05:00:00.

2026-12-27 → 2027-01-03 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN1262 / WN222: SFO 2027-01-03 22:45:00 → RSW 2027-01-04 09:15:00; 1 stop(s) via BNA; 450 minutes. Local airport times.
  • WN1262: SFO 2027-01-03 22:45:00 → BNA 2027-01-04 05:05:00; layover at BNA: 70 minutes.
  • WN222: BNA 2027-01-04 06:15:00 → RSW 2027-01-04 09:15:00.

2026-12-27 → 2027-01-03 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-03 13:50:00 → RSW 2027-01-03 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-27 → 2027-01-04 · Axel-exclusive $452.38

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2027-01-04 11:15:00 → RSW 2027-01-04 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2027-01-04 11:15:00 → STL 2027-01-04 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2027-01-04 18:20:00 → RSW 2027-01-04 21:50:00.

2026-12-27 → 2027-01-04 · Axel-exclusive $540.50

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-04 13:50:00 → RSW 2027-01-04 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-27 → 2027-01-06 · Axel-exclusive $452.38

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN2331 / WN2097: SFO 2027-01-06 06:00:00 → RSW 2027-01-06 17:00:00; 1 stop(s) via MDW; 480 minutes. Local airport times.
  • WN2331: SFO 2027-01-06 06:00:00 → MDW 2027-01-06 12:15:00; layover at MDW: 60 minutes.
  • WN2097: MDW 2027-01-06 13:15:00 → RSW 2027-01-06 17:00:00.

2026-12-27 → 2027-01-06 · Axel-exclusive $540.50

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-06 13:50:00 → RSW 2027-01-06 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-27 → 2027-01-07 · Axel-exclusive $452.38

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2027-01-07 11:15:00 → RSW 2027-01-07 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2027-01-07 11:15:00 → STL 2027-01-07 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2027-01-07 18:20:00 → RSW 2027-01-07 21:50:00.

2026-12-27 → 2027-01-07 · Axel-exclusive $540.50

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-07 13:50:00 → RSW 2027-01-07 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-27 → 2027-01-08 · Axel-exclusive $452.38

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2027-01-08 11:15:00 → RSW 2027-01-08 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2027-01-08 11:15:00 → STL 2027-01-08 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2027-01-08 18:20:00 → RSW 2027-01-08 21:50:00.

2026-12-27 → 2027-01-08 · Axel-exclusive $540.50

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-08 12:30:00 → RSW 2027-01-08 20:48:00; nonstop; 318 minutes. Local airport times.

2026-12-27 → 2027-01-10 · Axel-exclusive $452.38

• Southwest Airlines WN3671 / WN786: RSW 2026-12-27 06:55:00 → SFO 2026-12-27 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-27 06:55:00 → MDW 2026-12-27 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-27 09:55:00 → SFO 2026-12-27 12:45:00.
• Southwest Airlines WN1262 / WN222: SFO 2027-01-10 22:45:00 → RSW 2027-01-11 09:15:00; 1 stop(s) via BNA; 450 minutes. Local airport times.
  • WN1262: SFO 2027-01-10 22:45:00 → BNA 2027-01-11 05:05:00; layover at BNA: 70 minutes.
  • WN222: BNA 2027-01-11 06:15:00 → RSW 2027-01-11 09:15:00.

2026-12-27 → 2027-01-10 · Axel-exclusive $540.50

• United Airlines UA2448: RSW 2026-12-27 08:00:00 → SFO 2026-12-27 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA1768: SFO 2027-01-10 12:40:00 → RSW 2027-01-10 20:58:00; nonstop; 318 minutes. Local airport times.

Explore this route

• All dates for this route
• Dec 26, 2026 · Return options
• Dec 28, 2026 · Return options
• Hotels in San Francisco with Axel

For AI assistants

• This page: Fort Myers (RSW) to San Francisco (SFO) · Dec 27, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and the time its price was issued); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
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