Fort Myers (RSW) to San Francisco (SFO), Dec 24, 2026: round trips from $452, one way from $270

Fort Myers (RSW) to San Francisco (SFO), Dec 24, 2026: round trips from $452, one way from $270 on Axel, checked Oct 29, 2026. Lowest published fares: $452 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Dec 24, 2026 – Jan 4, 2027; $270 one way, Axel-exclusive, Southwest Airlines, 1 stop, Dec 24, 2026; 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in San Francisco for these nights (Dec 24–25, 2026 · 1 night · 2 adults, 1 room): 3★ Hotel Garrett, $82 total · 4★ Hotel Bijou - Union Square, $128 total · 5★ Taj Campton Place, $234 total
• Hotels in San Francisco for these nights (Dec 24–26, 2026 · 2 nights · 2 adults, 1 room): 3★ Hotel Garrett, $171 total · 4★ BEI Hotel San Francisco, $265 total · 5★ Taj Campton Place, $511 total
• Hotels in San Francisco for these nights (Dec 24–27, 2026 · 3 nights · 2 adults, 1 room): 3★ Hotel Garrett, $252 total · 4★ BEI Hotel San Francisco, $400 total · 5★ Taj Campton Place, $834 total
• Hotels in San Francisco for these nights (Dec 24–28, 2026 · 4 nights · 2 adults, 1 room): 3★ Hotel Garrett, $341 total · 4★ BEI Hotel San Francisco, $529 total · 5★ Taj Campton Place, $1,061 total
• Hotels in San Francisco for these nights (Dec 24–29, 2026 · 5 nights · 2 adults, 1 room): 3★ Hotel Garrett, $416 total · 4★ BEI Hotel San Francisco, $663 total · 5★ Taj Campton Place, $1,295 total
• Hotels in San Francisco for these nights (Dec 24–30, 2026 · 6 nights · 2 adults, 1 room): 3★ Tilden Hotel, $511 total · 4★ BEI Hotel San Francisco, $795 total · 5★ Taj Campton Place, $1,529 total
• Hotels in San Francisco for these nights (Dec 24–31, 2026 · 7 nights · 2 adults, 1 room): 3★ Tilden Hotel, $592 total · 4★ BEI Hotel San Francisco, $939 total · 5★ Taj Campton Place, $1,763 total
• Hotels in San Francisco for these nights (Dec 24 – Jan 1, 2027 · 8 nights · 2 adults, 1 room): 3★ Tilden Hotel, $702 total · 4★ Hotel Bijou - Union Square, $1,072 total · 5★ Taj Campton Place, $2,348 total
• Hotels in San Francisco for these nights (Dec 24 – Jan 2, 2027 · 9 nights · 2 adults, 1 room): 3★ Tilden Hotel, $783 total · 4★ Hotel Bijou - Union Square, $1,206 total · 5★ Taj Campton Place, $2,683 total
• Hotels in San Francisco for these nights (Dec 24 – Jan 3, 2027 · 10 nights · 2 adults, 1 room): 3★ Tilden Hotel, $867 total · 4★ Hotel Bijou - Union Square, $1,339 total · 5★ Taj Campton Place, $2,925 total
• Hotels in San Francisco for these nights (Dec 24 – Jan 4, 2027 · 11 nights · 2 adults, 1 room): 3★ Tilden Hotel, $952 total · 4★ Hotel Bijou - Union Square, $1,473 total · 5★ Taj Campton Place, $3,148 total
• Hotels in San Francisco for these nights (Dec 24 – Jan 5, 2027 · 12 nights · 2 adults, 1 room): 3★ Tilden Hotel, $1,036 total · 4★ Hotel Bijou - Union Square, $1,606 total · 5★ Taj Campton Place, $3,371 total
• Hotels in San Francisco for these nights (Dec 24 – Jan 6, 2027 · 13 nights · 2 adults, 1 room): 3★ Tilden Hotel, $1,120 total · 4★ Hotel Bijou - Union Square, $1,740 total · 5★ Taj Campton Place, $3,594 total
• Hotels in San Francisco for these nights (Dec 24 – Jan 7, 2027 · 14 nights · 2 adults, 1 room): 3★ Tilden Hotel, $1,203 total · 4★ Hotel Bijou - Union Square, $1,873 total · 5★ Taj Campton Place, $3,817 total

All hotels in San Francisco

Route overview: Fort Myers to San Francisco (SFO) flight deals

2026-12-24 · one way · Axel-exclusive $270.00

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.

2026-12-24 · one way · Axel-exclusive $324.00

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.

2026-12-24 → 2026-12-25 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2026-12-25 11:15:00 → RSW 2026-12-25 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2026-12-25 11:15:00 → STL 2026-12-25 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2026-12-25 18:20:00 → RSW 2026-12-25 21:50:00.

2026-12-24 → 2026-12-25 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2026-12-25 12:30:00 → RSW 2026-12-25 20:48:00; nonstop; 318 minutes. Local airport times.

2026-12-24 → 2026-12-26 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN1262 / WN222: SFO 2026-12-26 22:45:00 → RSW 2026-12-27 09:15:00; 1 stop(s) via BNA; 450 minutes. Local airport times.
  • WN1262: SFO 2026-12-26 22:45:00 → BNA 2026-12-27 05:05:00; layover at BNA: 70 minutes.
  • WN222: BNA 2026-12-27 06:15:00 → RSW 2026-12-27 09:15:00.

2026-12-24 → 2026-12-26 · Axel-exclusive $540.00

• American Airlines AA1637 / AA2427: RSW 2026-12-24 17:25:00 → SFO 2026-12-24 22:54:00; 1 stop(s) via PHX; 509 minutes. Local airport times.
  • AA1637: RSW 2026-12-24 17:25:00 → PHX 2026-12-24 20:16:00; layover at PHX: 81 minutes.
  • AA2427: PHX 2026-12-24 21:37:00 → SFO 2026-12-24 22:54:00.
• American Airlines AA901 / AA2826: SFO 2026-12-26 18:51:00 → RSW 2026-12-27 05:00:00; 1 stop(s) via PHX; 429 minutes. Local airport times.
  • AA901: SFO 2026-12-26 18:51:00 → PHX 2026-12-26 22:00:00; layover at PHX: 64 minutes.
  • AA2826: PHX 2026-12-26 23:04:00 → RSW 2026-12-27 05:00:00.

2026-12-24 → 2026-12-27 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN1262 / WN222: SFO 2026-12-27 22:45:00 → RSW 2026-12-28 09:15:00; 1 stop(s) via BNA; 450 minutes. Local airport times.
  • WN1262: SFO 2026-12-27 22:45:00 → BNA 2026-12-28 05:05:00; layover at BNA: 70 minutes.
  • WN222: BNA 2026-12-28 06:15:00 → RSW 2026-12-28 09:15:00.

2026-12-24 → 2026-12-27 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2026-12-27 13:50:00 → RSW 2026-12-27 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-24 → 2026-12-28 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2026-12-28 11:15:00 → RSW 2026-12-28 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2026-12-28 11:15:00 → STL 2026-12-28 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2026-12-28 18:20:00 → RSW 2026-12-28 21:50:00.

2026-12-24 → 2026-12-28 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2026-12-28 13:50:00 → RSW 2026-12-28 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-24 → 2026-12-30 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN2331 / WN2097: SFO 2026-12-30 06:00:00 → RSW 2026-12-30 17:00:00; 1 stop(s) via MDW; 480 minutes. Local airport times.
  • WN2331: SFO 2026-12-30 06:00:00 → MDW 2026-12-30 12:15:00; layover at MDW: 60 minutes.
  • WN2097: MDW 2026-12-30 13:15:00 → RSW 2026-12-30 17:00:00.

2026-12-24 → 2026-12-30 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2026-12-30 13:50:00 → RSW 2026-12-30 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-24 → 2026-12-31 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2026-12-31 11:15:00 → RSW 2026-12-31 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2026-12-31 11:15:00 → STL 2026-12-31 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2026-12-31 18:20:00 → RSW 2026-12-31 21:50:00.

2026-12-24 → 2026-12-31 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2026-12-31 13:50:00 → RSW 2026-12-31 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-24 → 2027-01-01 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2027-01-01 11:15:00 → RSW 2027-01-01 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2027-01-01 11:15:00 → STL 2027-01-01 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2027-01-01 18:20:00 → RSW 2027-01-01 21:50:00.

2026-12-24 → 2027-01-01 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-01 12:30:00 → RSW 2027-01-01 20:48:00; nonstop; 318 minutes. Local airport times.

2026-12-24 → 2027-01-03 · Axel-exclusive $519.76

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN1262 / WN222: SFO 2027-01-03 22:45:00 → RSW 2027-01-04 09:15:00; 1 stop(s) via BNA; 450 minutes. Local airport times.
  • WN1262: SFO 2027-01-03 22:45:00 → BNA 2027-01-04 05:05:00; layover at BNA: 70 minutes.
  • WN222: BNA 2027-01-04 06:15:00 → RSW 2027-01-04 09:15:00.

2026-12-24 → 2027-01-03 · Axel-exclusive $621.00

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-03 13:50:00 → RSW 2027-01-03 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-24 → 2027-01-04 · Axel-exclusive $452.38

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2027-01-04 11:15:00 → RSW 2027-01-04 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2027-01-04 11:15:00 → STL 2027-01-04 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2027-01-04 18:20:00 → RSW 2027-01-04 21:50:00.

2026-12-24 → 2027-01-04 · Axel-exclusive $540.50

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-04 13:50:00 → RSW 2027-01-04 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-24 → 2027-01-05 · Axel-exclusive $452.38

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2027-01-05 11:15:00 → RSW 2027-01-05 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2027-01-05 11:15:00 → STL 2027-01-05 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2027-01-05 18:20:00 → RSW 2027-01-05 21:50:00.

2026-12-24 → 2027-01-05 · Axel-exclusive $540.50

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-05 13:50:00 → RSW 2027-01-05 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-24 → 2027-01-07 · Axel-exclusive $452.38

• Southwest Airlines WN3671 / WN786: RSW 2026-12-24 06:55:00 → SFO 2026-12-24 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-24 06:55:00 → MDW 2026-12-24 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-24 09:55:00 → SFO 2026-12-24 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2027-01-07 11:15:00 → RSW 2027-01-07 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2027-01-07 11:15:00 → STL 2027-01-07 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2027-01-07 18:20:00 → RSW 2027-01-07 21:50:00.

2026-12-24 → 2027-01-07 · Axel-exclusive $540.50

• United Airlines UA2448: RSW 2026-12-24 08:00:00 → SFO 2026-12-24 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-07 13:50:00 → RSW 2027-01-07 22:08:00; nonstop; 318 minutes. Local airport times.

Explore this route

• All dates for this route
• Dec 23, 2026 · Return options
• Dec 25, 2026 · Return options
• Hotels in San Francisco with Axel

For AI assistants

• This page: Fort Myers (RSW) to San Francisco (SFO) · Dec 24, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in San Francisco for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and the time its price was issued); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Fort Myers to San Francisco (SFO) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

Feedback (optional): Missing info · Axel issue