Fort Myers (RSW) to San Francisco (SFO) · Dec 22, 2026 · return Jan 5, 2027

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in San Francisco for these nights (Dec 22 – Jan 5, 2027 · 14 nights · 2 adults, 1 room): 3★ Hotel Griffon, $1,599 total · 4★ Parc 55 San Francisco-A Hilton Hotel, $1,768 total · 5★ Taj Campton Place, $3,798 total

All hotels in San Francisco

Route overview: Fort Myers to San Francisco (SFO) flight deals

2026-12-22 → 2027-01-05 · Axel-exclusive $540.50

• United Airlines UA2448: RSW 2026-12-22 08:00:00 → SFO 2026-12-22 11:22:00; nonstop; 382 minutes. Local airport times.
• United Airlines UA2778: SFO 2027-01-05 13:50:00 → RSW 2027-01-05 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-22 → 2027-01-05 · Axel-exclusive $452.38

• Southwest Airlines WN3671 / WN786: RSW 2026-12-22 06:55:00 → SFO 2026-12-22 12:45:00; 1 stop(s) via MDW; 530 minutes. Local airport times.
  • WN3671: RSW 2026-12-22 06:55:00 → MDW 2026-12-22 08:55:00; layover at MDW: 60 minutes.
  • WN786: MDW 2026-12-22 09:55:00 → SFO 2026-12-22 12:45:00.
• Southwest Airlines WN2989 / WN4196: SFO 2027-01-05 11:15:00 → RSW 2027-01-05 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2027-01-05 11:15:00 → STL 2027-01-05 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2027-01-05 18:20:00 → RSW 2027-01-05 21:50:00.

2026-12-22 → 2027-01-05 · Axel-exclusive $470.00

• American Airlines AA1637 / AA2427: RSW 2026-12-22 17:25:00 → SFO 2026-12-22 22:54:00; 1 stop(s) via PHX; 509 minutes. Local airport times.
  • AA1637: RSW 2026-12-22 17:25:00 → PHX 2026-12-22 20:16:00; layover at PHX: 81 minutes.
  • AA2427: PHX 2026-12-22 21:37:00 → SFO 2026-12-22 22:54:00.
• American Airlines AA901 / AA2826: SFO 2027-01-05 18:51:00 → RSW 2027-01-06 05:00:00; 1 stop(s) via PHX; 429 minutes. Local airport times.
  • AA901: SFO 2027-01-05 18:51:00 → PHX 2027-01-05 22:00:00; layover at PHX: 64 minutes.
  • AA2826: PHX 2027-01-05 23:04:00 → RSW 2027-01-06 05:00:00.

2026-12-22 → 2027-01-05 · Axel-exclusive $520.25

• Delta Air Lines DL2400 / DL2809: RSW 2026-12-22 14:45:00 → SFO 2026-12-22 20:49:00; 1 stop(s) via MSP; 544 minutes. Local airport times.
  • DL2400: RSW 2026-12-22 14:45:00 → MSP 2026-12-22 17:25:00; layover at MSP: 64 minutes.
  • DL2809: MSP 2026-12-22 18:29:00 → SFO 2026-12-22 20:49:00.
• United Airlines UA2778: SFO 2027-01-05 13:50:00 → RSW 2027-01-05 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-22 → 2027-01-05 · Axel-exclusive $452.38

• Southwest Airlines WN3929 / WN4813: RSW 2026-12-22 16:50:00 → SFO 2026-12-22 23:00:00; 1 stop(s) via BNA; 550 minutes. Local airport times.
  • WN3929: RSW 2026-12-22 16:50:00 → BNA 2026-12-22 18:00:00; layover at BNA: 115 minutes.
  • WN4813: BNA 2026-12-22 19:55:00 → SFO 2026-12-22 23:00:00.
• Southwest Airlines WN2989 / WN4196: SFO 2027-01-05 11:15:00 → RSW 2027-01-05 21:50:00; 1 stop(s) via STL; 455 minutes. Local airport times.
  • WN2989: SFO 2027-01-05 11:15:00 → STL 2027-01-05 17:10:00; layover at STL: 70 minutes.
  • WN4196: STL 2027-01-05 18:20:00 → RSW 2027-01-05 21:50:00.

2026-12-22 → 2027-01-05 · Axel-exclusive $506.75

• United Airlines UA1300 / UA1389: RSW 2026-12-22 15:52:00 → SFO 2026-12-22 21:10:00; 1 stop(s) via DEN; 498 minutes. Local airport times.
  • UA1300: RSW 2026-12-22 15:52:00 → DEN 2026-12-22 18:16:00; layover at DEN: 64 minutes.
  • UA1389: DEN 2026-12-22 19:20:00 → SFO 2026-12-22 21:10:00.
• United Airlines UA2778: SFO 2027-01-05 13:50:00 → RSW 2027-01-05 22:08:00; nonstop; 318 minutes. Local airport times.

2026-12-22 → 2027-01-05 · Axel-exclusive $506.75

• United Airlines UA676 / UA1535: RSW 2026-12-22 14:29:00 → SFO 2026-12-22 20:10:00; 1 stop(s) via IAH; 521 minutes. Local airport times.
  • UA676: RSW 2026-12-22 14:29:00 → IAH 2026-12-22 16:17:00; layover at IAH: 88 minutes.
  • UA1535: IAH 2026-12-22 17:45:00 → SFO 2026-12-22 20:10:00.
• United Airlines UA2778: SFO 2027-01-05 13:50:00 → RSW 2027-01-05 22:08:00; nonstop; 318 minutes. Local airport times.

Explore this route

• All dates for this route
• Dec 21, 2026 · Return options
• Dec 23, 2026 · Return options
• Hotels in San Francisco with Axel

For AI assistants

• This page: Fort Myers (RSW) to San Francisco (SFO) · Dec 22, 2026 · return Jan 5, 2027: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in San Francisco for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
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