Fort Myers (RSW) to Buffalo (BUF) · Nov 17, 2026 · return Nov 26, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Fort Myers to Buffalo (BUF) flight deals

2026-11-17 → 2026-11-26 · Axel-exclusive $356.50

• Southwest Airlines WN4492 / WN2448: RSW 2026-11-17 07:10:00 → BUF 2026-11-17 13:00:00; 1 stop(s) via MCO; 350 minutes. Local airport times.
  • WN4492: RSW 2026-11-17 07:10:00 → MCO 2026-11-17 08:05:00; layover at MCO: 125 minutes.
  • WN2448: MCO 2026-11-17 10:10:00 → BUF 2026-11-17 13:00:00.
• Southwest Airlines WN2381 / WN2231: BUF 2026-11-26 15:05:00 → RSW 2026-11-26 21:10:00; 1 stop(s) via BWI; 365 minutes. Local airport times.
  • WN2381: BUF 2026-11-26 15:05:00 → BWI 2026-11-26 16:20:00; layover at BWI: 120 minutes.
  • WN2231: BWI 2026-11-26 18:20:00 → RSW 2026-11-26 21:10:00.

2026-11-17 → 2026-11-26 · Axel-exclusive $399.75

• JetBlue Airways B61530 / B6802: RSW 2026-11-17 10:10:00 → BUF 2026-11-17 15:54:00; 1 stop(s) via JFK; 344 minutes. Local airport times.
  • B61530: RSW 2026-11-17 10:10:00 → JFK 2026-11-17 12:55:00; layover at JFK: 90 minutes.
  • B6802: JFK 2026-11-17 14:25:00 → BUF 2026-11-17 15:54:00.
• Delta Air Lines DL4636 / DL1225: BUF 2026-11-26 12:00:00 → RSW 2026-11-26 17:18:00; 1 stop(s) via DTW; 318 minutes. Local airport times.
  • DL4636: BUF 2026-11-26 12:00:00 → DTW 2026-11-26 13:17:00; layover at DTW: 72 minutes.
  • DL1225: DTW 2026-11-26 14:29:00 → RSW 2026-11-26 17:18:00.

2026-11-17 → 2026-11-26 · Axel-exclusive $408.25

• United Airlines UA365 / UA3413: RSW 2026-11-17 17:48:00 → BUF 2026-11-17 23:34:00; 1 stop(s) via EWR; 346 minutes. Local airport times.
  • UA365: RSW 2026-11-17 17:48:00 → EWR 2026-11-17 20:40:00; layover at EWR: 75 minutes.
  • UA3413: EWR 2026-11-17 21:55:00 → BUF 2026-11-17 23:34:00.
• United Airlines UA6157 / UA2660: BUF 2026-11-26 10:00:00 → RSW 2026-11-26 15:27:00; 1 stop(s) via IAD; 327 minutes. Local airport times.
  • UA6157: BUF 2026-11-26 10:00:00 → IAD 2026-11-26 11:28:00; layover at IAD: 67 minutes.
  • UA2660: IAD 2026-11-26 12:35:00 → RSW 2026-11-26 15:27:00.

2026-11-17 → 2026-11-26 · Axel-exclusive $419.75

• Delta Air Lines DL3094 / DL4636: RSW 2026-11-17 06:00:00 → BUF 2026-11-17 11:24:00; 1 stop(s) via DTW; 324 minutes. Local airport times.
  • DL3094: RSW 2026-11-17 06:00:00 → DTW 2026-11-17 08:59:00; layover at DTW: 61 minutes.
  • DL4636: DTW 2026-11-17 10:00:00 → BUF 2026-11-17 11:24:00.
• Delta Air Lines DL4636 / DL1225: BUF 2026-11-26 12:00:00 → RSW 2026-11-26 17:18:00; 1 stop(s) via DTW; 318 minutes. Local airport times.
  • DL4636: BUF 2026-11-26 12:00:00 → DTW 2026-11-26 13:17:00; layover at DTW: 72 minutes.
  • DL1225: DTW 2026-11-26 14:29:00 → RSW 2026-11-26 17:18:00.

2026-11-17 → 2026-11-26 · Axel-exclusive $371.50

• Southwest Airlines WN3207: RSW 2026-11-17 10:05:00 → BUF 2026-11-17 13:00:00; nonstop; 175 minutes. Local airport times.
• Southwest Airlines WN2381 / WN2231: BUF 2026-11-26 15:05:00 → RSW 2026-11-26 21:10:00; 1 stop(s) via BWI; 365 minutes. Local airport times.
  • WN2381: BUF 2026-11-26 15:05:00 → BWI 2026-11-26 16:20:00; layover at BWI: 120 minutes.
  • WN2231: BWI 2026-11-26 18:20:00 → RSW 2026-11-26 21:10:00.

2026-11-17 → 2026-11-26 · Axel-exclusive $419.75

• Delta Air Lines DL1385 / DL1384: RSW 2026-11-17 05:30:00 → BUF 2026-11-17 11:06:00; 1 stop(s) via ATL; 336 minutes. Local airport times.
  • DL1385: RSW 2026-11-17 05:30:00 → ATL 2026-11-17 07:17:00; layover at ATL: 109 minutes.
  • DL1384: ATL 2026-11-17 09:06:00 → BUF 2026-11-17 11:06:00.
• Delta Air Lines DL4636 / DL1225: BUF 2026-11-26 12:00:00 → RSW 2026-11-26 17:18:00; 1 stop(s) via DTW; 318 minutes. Local airport times.
  • DL4636: BUF 2026-11-26 12:00:00 → DTW 2026-11-26 13:17:00; layover at DTW: 72 minutes.
  • DL1225: DTW 2026-11-26 14:29:00 → RSW 2026-11-26 17:18:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 16, 2026 · Return options
• Nov 18, 2026 · Return options
• Hotels in Buffalo with Axel

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