Fort Myers (RSW) to Buffalo (BUF) · Nov 13, 2026 · return Nov 27, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Fort Myers to Buffalo (BUF) flight deals

2026-11-13 → 2026-11-27 · Axel-exclusive $356.50

• Southwest Airlines WN4492 / WN2448: RSW 2026-11-13 07:10:00 → BUF 2026-11-13 13:00:00; 1 stop(s) via MCO; 350 minutes. Local airport times.
  • WN4492: RSW 2026-11-13 07:10:00 → MCO 2026-11-13 08:05:00; layover at MCO: 125 minutes.
  • WN2448: MCO 2026-11-13 10:10:00 → BUF 2026-11-13 13:00:00.
• Southwest Airlines WN839 / WN2777: BUF 2026-11-27 05:35:00 → RSW 2026-11-27 11:45:00; 1 stop(s) via MCO; 370 minutes. Local airport times.
  • WN839: BUF 2026-11-27 05:35:00 → MCO 2026-11-27 08:20:00; layover at MCO: 140 minutes.
  • WN2777: MCO 2026-11-27 10:40:00 → RSW 2026-11-27 11:45:00.

2026-11-13 → 2026-11-27 · Axel-exclusive $393.25

• JetBlue Airways B61530 / B6802: RSW 2026-11-13 10:10:00 → BUF 2026-11-13 15:54:00; 1 stop(s) via JFK; 344 minutes. Local airport times.
  • B61530: RSW 2026-11-13 10:10:00 → JFK 2026-11-13 12:55:00; layover at JFK: 90 minutes.
  • B6802: JFK 2026-11-13 14:25:00 → BUF 2026-11-13 15:54:00.
• United Airlines UA6157 / UA2660: BUF 2026-11-27 10:00:00 → RSW 2026-11-27 15:27:00; 1 stop(s) via IAD; 327 minutes. Local airport times.
  • UA6157: BUF 2026-11-27 10:00:00 → IAD 2026-11-27 11:28:00; layover at IAD: 67 minutes.
  • UA2660: IAD 2026-11-27 12:35:00 → RSW 2026-11-27 15:27:00.

2026-11-13 → 2026-11-27 · Axel-exclusive $408.25

• United Airlines UA365 / UA3413: RSW 2026-11-13 17:48:00 → BUF 2026-11-13 23:34:00; 1 stop(s) via EWR; 346 minutes. Local airport times.
  • UA365: RSW 2026-11-13 17:48:00 → EWR 2026-11-13 20:40:00; layover at EWR: 75 minutes.
  • UA3413: EWR 2026-11-13 21:55:00 → BUF 2026-11-13 23:34:00.
• United Airlines UA6157 / UA2660: BUF 2026-11-27 10:00:00 → RSW 2026-11-27 15:27:00; 1 stop(s) via IAD; 327 minutes. Local airport times.
  • UA6157: BUF 2026-11-27 10:00:00 → IAD 2026-11-27 11:28:00; layover at IAD: 67 minutes.
  • UA2660: IAD 2026-11-27 12:35:00 → RSW 2026-11-27 15:27:00.

2026-11-13 → 2026-11-27 · Axel-exclusive $419.75

• Delta Air Lines DL1385 / DL1384: RSW 2026-11-13 05:30:00 → BUF 2026-11-13 11:06:00; 1 stop(s) via ATL; 336 minutes. Local airport times.
  • DL1385: RSW 2026-11-13 05:30:00 → ATL 2026-11-13 07:17:00; layover at ATL: 109 minutes.
  • DL1384: ATL 2026-11-13 09:06:00 → BUF 2026-11-13 11:06:00.
• Delta Air Lines DL4636 / DL1225: BUF 2026-11-27 12:00:00 → RSW 2026-11-27 17:18:00; 1 stop(s) via DTW; 318 minutes. Local airport times.
  • DL4636: BUF 2026-11-27 12:00:00 → DTW 2026-11-27 13:17:00; layover at DTW: 72 minutes.
  • DL1225: DTW 2026-11-27 14:29:00 → RSW 2026-11-27 17:18:00.

2026-11-13 → 2026-11-27 · Axel-exclusive $371.50

• Southwest Airlines WN3207: RSW 2026-11-13 10:05:00 → BUF 2026-11-13 13:00:00; nonstop; 175 minutes. Local airport times.
• Southwest Airlines WN839 / WN2777: BUF 2026-11-27 05:35:00 → RSW 2026-11-27 11:45:00; 1 stop(s) via MCO; 370 minutes. Local airport times.
  • WN839: BUF 2026-11-27 05:35:00 → MCO 2026-11-27 08:20:00; layover at MCO: 140 minutes.
  • WN2777: MCO 2026-11-27 10:40:00 → RSW 2026-11-27 11:45:00.

2026-11-13 → 2026-11-27 · Axel-exclusive $419.75

• Delta Air Lines DL3094 / DL4636: RSW 2026-11-13 06:00:00 → BUF 2026-11-13 11:24:00; 1 stop(s) via DTW; 324 minutes. Local airport times.
  • DL3094: RSW 2026-11-13 06:00:00 → DTW 2026-11-13 08:59:00; layover at DTW: 61 minutes.
  • DL4636: DTW 2026-11-13 10:00:00 → BUF 2026-11-13 11:24:00.
• Delta Air Lines DL4636 / DL1225: BUF 2026-11-27 12:00:00 → RSW 2026-11-27 17:18:00; 1 stop(s) via DTW; 318 minutes. Local airport times.
  • DL4636: BUF 2026-11-27 12:00:00 → DTW 2026-11-27 13:17:00; layover at DTW: 72 minutes.
  • DL1225: DTW 2026-11-27 14:29:00 → RSW 2026-11-27 17:18:00.

Explore this route

• All dates for this route
• Nov 12, 2026 · Return options
• Nov 14, 2026 · Return options
• Hotels in Buffalo with Axel

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