# Raleigh/Durham (RDU) to Saint Louis (STL), Nov 29, 2026: round trips from $348, one way from $209 Raleigh/Durham (RDU) to Saint Louis (STL), Nov 29, 2026: round trips from $348, one way from $209 on Axel, checked Nov 11, 2026. Lowest published fares: $348 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 29, 2026 – Dec 2, 2026; $209 one way, Axel-exclusive, Southwest Airlines, nonstop, Nov 29, 2026; 1 adult, economy, checked Nov 11, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply. **Prices by return date:** match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown. **Date links** open published trip details for exploration. **Price links** open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here. | Exact travel dates | Airline | Flights | Times, duration, stops | Total price | Price checked | | --- | --- | --- | --- | ---: | --- | | [2026-11-29 · one way](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/one-way) | Southwest Airlines | WN3623 | 20:50:00→22:00:00 2h 10m nonstop | [Axel-exclusive $209.25](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/trip/one-way/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 · one way](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/one-way) | American Airlines | AA1391 + AA4458 | 06:00:00→10:08:00 5h 08m 1 stop via DCA | [Axel-exclusive $236.25](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/trip/one-way/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-11-30](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/nov-30) | Southwest Airlines | WN3623 / WN665 + WN4766 | 20:50:00→22:00:00 2h 10m nonstop · 10:35:00→16:35:00 5h 00m 1 stop via BNA | [Axel-exclusive $398.25](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/november-30-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-11-30](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/nov-30) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $459.00](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/november-30-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-01](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-1) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-1-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-01](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-1) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-1-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-02](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-2) | Southwest Airlines | WN3623 / WN4173 + WN2501 | 20:50:00→22:00:00 2h 10m nonstop · 05:30:00→10:40:00 4h 10m 1 stop via MDW | [Axel-exclusive $347.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-2-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-02](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-2) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-2-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-03](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-3) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-3-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-03](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-3) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-3-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-04](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-4) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-4-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-04](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-4) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-4-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-05](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-5) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-5-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-05](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-5) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-5-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-06](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-6) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-6-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-06](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-6) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-6-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-07](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-7) | Southwest Airlines | WN3623 / WN665 + WN4766 | 20:50:00→22:00:00 2h 10m nonstop · 10:35:00→16:35:00 5h 00m 1 stop via BNA | [Axel-exclusive $347.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-7-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-07](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-7) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-7-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-08](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-8) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-8-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-08](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-8) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-8-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-09](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-9) | Southwest Airlines | WN3623 / WN4173 + WN2501 | 20:50:00→22:00:00 2h 10m nonstop · 05:30:00→10:40:00 4h 10m 1 stop via MDW | [Axel-exclusive $347.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-9-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-09](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-9) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-9-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-10](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-10) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-10-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-10](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-10) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-10-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-11](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-11) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-11-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-11](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-11) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-11-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-12](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-12) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-12-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-12](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-12) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-12-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-13](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-13) | Southwest Airlines | WN3623 / WN4192 | 20:50:00→22:00:00 2h 10m nonstop · 10:15:00→13:05:00 1h 50m nonstop | [Axel-exclusive $352.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-13-2026/adults/1/cabin/economy) | Nov 11, 2026 | | [2026-11-29 → 2026-12-13](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29/dec-13) | American Airlines | AA1391 + AA4458 / AA2486 + AA1904 | 06:00:00→10:08:00 5h 08m 1 stop via DCA · 12:54:00→18:29:00 4h 35m 1 stop via CLT | [Axel-exclusive $399.50](https://helloaxel.com/en/f/start/from/rdu/to/stl/depart/november-29-2026/return/december-13-2026/adults/1/cabin/economy) | Nov 11, 2026 | ### Hotels in St. Louis for these trips **Hotels:** under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates. - Hotels in St. Louis for these nights (Nov 29–30, 2026 · 1 night · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $66 a night](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-11-30/2-adults) · 4★ [Hilton St. Louis at the Ballpark, $105 a night](https://helloaxel.com/en/hotels/st-louis/hilton-st-louis-at-the-ballpark-1035797/2026-11-29/2026-11-30/2-adults) · 5★ [Four Seasons Hotel St Louis, $367 a night](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-11-30/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 1, 2026 · 2 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $60 a night, $120 for 2 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-01/2-adults) · 4★ [Hilton St. Louis at the Ballpark, $105 a night, $209 for 2 nights](https://helloaxel.com/en/hotels/st-louis/hilton-st-louis-at-the-ballpark-1035797/2026-11-29/2026-12-01/2-adults) · 5★ [Four Seasons Hotel St Louis, $367 a night, $733 for 2 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-01/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 2, 2026 · 3 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $65 a night, $194 for 3 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-02/2-adults) · 4★ [Hilton St. Louis at the Ballpark, $105 a night, $314 for 3 nights](https://helloaxel.com/en/hotels/st-louis/hilton-st-louis-at-the-ballpark-1035797/2026-11-29/2026-12-02/2-adults) · 5★ [Four Seasons Hotel St Louis, $366 a night, $1,099 for 3 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-02/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 3, 2026 · 4 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $64 a night, $255 for 4 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-03/2-adults) · 4★ [Hilton St. Louis at the Ballpark, $105 a night, $419 for 4 nights](https://helloaxel.com/en/hotels/st-louis/hilton-st-louis-at-the-ballpark-1035797/2026-11-29/2026-12-03/2-adults) · 5★ [Four Seasons Hotel St Louis, $366 a night, $1,465 for 4 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-03/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 4, 2026 · 5 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $64 a night, $319 for 5 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-04/2-adults) · 4★ [Hilton St. Louis at the Ballpark, $105 a night, $524 for 5 nights](https://helloaxel.com/en/hotels/st-louis/hilton-st-louis-at-the-ballpark-1035797/2026-11-29/2026-12-04/2-adults) · 5★ [Four Seasons Hotel St Louis, $403 a night, $2,015 for 5 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-04/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 5, 2026 · 6 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $65 a night, $392 for 6 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-05/2-adults) · 4★ [CozySuites Central West End, $142 a night, $849 for 6 nights](https://helloaxel.com/en/hotels/st-louis/cozysuites-central-west-end-1342947/2026-11-29/2026-12-05/2-adults) · 5★ [Four Seasons Hotel St Louis, $420 a night, $2,517 for 6 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-05/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 6, 2026 · 7 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $67 a night, $467 for 7 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-06/2-adults) · 4★ [CozySuites Central West End, $145 a night, $1,017 for 7 nights](https://helloaxel.com/en/hotels/st-louis/cozysuites-central-west-end-1342947/2026-11-29/2026-12-06/2-adults) · 5★ [Four Seasons Hotel St Louis, $422 a night, $2,951 for 7 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-06/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 7, 2026 · 8 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $66 a night, $529 for 8 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-07/2-adults) · 4★ [CozySuites Central West End, $143 a night, $1,144 for 8 nights](https://helloaxel.com/en/hotels/st-louis/cozysuites-central-west-end-1342947/2026-11-29/2026-12-07/2-adults) · 5★ [Four Seasons Hotel St Louis, $415 a night, $3,317 for 8 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-07/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 8, 2026 · 9 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $67 a night, $603 for 9 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-08/2-adults) · 4★ [CozySuites Central West End, $141 a night, $1,271 for 9 nights](https://helloaxel.com/en/hotels/st-louis/cozysuites-central-west-end-1342947/2026-11-29/2026-12-08/2-adults) · 5★ [Four Seasons Hotel St Louis, $409 a night, $3,683 for 9 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-08/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 9, 2026 · 10 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $67 a night, $667 for 10 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-09/2-adults) · 4★ [CozySuites Central West End, $140 a night, $1,396 for 10 nights](https://helloaxel.com/en/hotels/st-louis/cozysuites-central-west-end-1342947/2026-11-29/2026-12-09/2-adults) · 5★ [Four Seasons Hotel St Louis, $405 a night, $4,049 for 10 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-09/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 10, 2026 · 11 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $67 a night, $741 for 11 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-10/2-adults) · 4★ [CozySuites Central West End, $138 a night, $1,519 for 11 nights](https://helloaxel.com/en/hotels/st-louis/cozysuites-central-west-end-1342947/2026-11-29/2026-12-10/2-adults) · 5★ [Four Seasons Hotel St Louis, $401 a night, $4,415 for 11 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-10/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 11, 2026 · 12 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $67 a night, $806 for 12 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-11/2-adults) · 4★ [CozySuites Central West End, $139 a night, $1,664 for 12 nights](https://helloaxel.com/en/hotels/st-louis/cozysuites-central-west-end-1342947/2026-11-29/2026-12-11/2-adults) · 5★ [Four Seasons Hotel St Louis, $398 a night, $4,781 for 12 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-11/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 12, 2026 · 13 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $68 a night, $880 for 13 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-12/2-adults) · 4★ [The Westin St. Louis, $139 a night, $1,808.50 for 13 nights](https://helloaxel.com/en/hotels/st-louis/the-westin-st-louis-1199215/2026-11-29/2026-12-12/2-adults) · 5★ [Four Seasons Hotel St Louis, $396 a night, $5,147 for 13 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-12/2-adults) - Hotels in St. Louis for these nights (Nov 29 – Dec 13, 2026 · 14 nights · 2 adults, 1 room): 3★ [Clayton Plaza Hotel & Extended Stay, $68 a night, $954 for 14 nights](https://helloaxel.com/en/hotels/st-louis/clayton-plaza-hotel-extended-stay-1068323/2026-11-29/2026-12-13/2-adults) · 4★ [The Westin St. Louis, $137 a night, $1,922.50 for 14 nights](https://helloaxel.com/en/hotels/st-louis/the-westin-st-louis-1199215/2026-11-29/2026-12-13/2-adults) · 5★ [Four Seasons Hotel St Louis, $394 a night, $5,513 for 14 nights](https://helloaxel.com/en/hotels/st-louis/four-seasons-hotel-st-louis-1390247/2026-11-29/2026-12-13/2-adults) [All hotels in St. Louis](https://helloaxel.com/en/hotels/destinations/st-louis) [Route overview: Raleigh/Durham to Saint Louis (STL) flight deals](/en/flights/from-raleigh-durham-to-saint-louis-stl) ### 2026-11-29 · one way · Axel-exclusive $209.25 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. ### 2026-11-29 · one way · Axel-exclusive $236.25 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. ### 2026-11-29 → 2026-11-30 · Axel-exclusive $398.25 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN665 / WN4766: STL 2026-11-30 10:35:00 → RDU 2026-11-30 16:35:00; 1 stop(s) via BNA; 300 minutes. Local airport times. - WN665: STL 2026-11-30 10:35:00 → BNA 2026-11-30 11:40:00; layover at BNA: 145 minutes. - WN4766: BNA 2026-11-30 14:05:00 → RDU 2026-11-30 16:35:00. ### 2026-11-29 → 2026-11-30 · Axel-exclusive $459.00 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-11-30 12:54:00 → RDU 2026-11-30 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-11-30 12:54:00 → CLT 2026-11-30 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-11-30 17:30:00 → RDU 2026-11-30 18:29:00. ### 2026-11-29 → 2026-12-01 · Axel-exclusive $352.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN4192: STL 2026-12-01 10:15:00 → RDU 2026-12-01 13:05:00; nonstop; 110 minutes. Local airport times. ### 2026-11-29 → 2026-12-01 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-01 12:54:00 → RDU 2026-12-01 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-01 12:54:00 → CLT 2026-12-01 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-01 17:30:00 → RDU 2026-12-01 18:29:00. ### 2026-11-29 → 2026-12-02 · Axel-exclusive $347.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN4173 / WN2501: STL 2026-12-02 05:30:00 → RDU 2026-12-02 10:40:00; 1 stop(s) via MDW; 250 minutes. Local airport times. - WN4173: STL 2026-12-02 05:30:00 → MDW 2026-12-02 06:35:00; layover at MDW: 70 minutes. - WN2501: MDW 2026-12-02 07:45:00 → RDU 2026-12-02 10:40:00. ### 2026-11-29 → 2026-12-02 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-02 12:54:00 → RDU 2026-12-02 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-02 12:54:00 → CLT 2026-12-02 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-02 17:30:00 → RDU 2026-12-02 18:29:00. ### 2026-11-29 → 2026-12-03 · Axel-exclusive $352.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN4192: STL 2026-12-03 10:15:00 → RDU 2026-12-03 13:05:00; nonstop; 110 minutes. Local airport times. ### 2026-11-29 → 2026-12-03 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-03 12:54:00 → RDU 2026-12-03 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-03 12:54:00 → CLT 2026-12-03 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-03 17:30:00 → RDU 2026-12-03 18:29:00. ### 2026-11-29 → 2026-12-05 · Axel-exclusive $352.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN4192: STL 2026-12-05 10:15:00 → RDU 2026-12-05 13:05:00; nonstop; 110 minutes. Local airport times. ### 2026-11-29 → 2026-12-05 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-05 12:54:00 → RDU 2026-12-05 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-05 12:54:00 → CLT 2026-12-05 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-05 17:30:00 → RDU 2026-12-05 18:29:00. ### 2026-11-29 → 2026-12-06 · Axel-exclusive $352.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN4192: STL 2026-12-06 10:15:00 → RDU 2026-12-06 13:05:00; nonstop; 110 minutes. Local airport times. ### 2026-11-29 → 2026-12-06 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-06 12:54:00 → RDU 2026-12-06 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-06 12:54:00 → CLT 2026-12-06 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-06 17:30:00 → RDU 2026-12-06 18:29:00. ### 2026-11-29 → 2026-12-07 · Axel-exclusive $347.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN665 / WN4766: STL 2026-12-07 10:35:00 → RDU 2026-12-07 16:35:00; 1 stop(s) via BNA; 300 minutes. Local airport times. - WN665: STL 2026-12-07 10:35:00 → BNA 2026-12-07 11:40:00; layover at BNA: 145 minutes. - WN4766: BNA 2026-12-07 14:05:00 → RDU 2026-12-07 16:35:00. ### 2026-11-29 → 2026-12-07 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-07 12:54:00 → RDU 2026-12-07 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-07 12:54:00 → CLT 2026-12-07 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-07 17:30:00 → RDU 2026-12-07 18:29:00. ### 2026-11-29 → 2026-12-09 · Axel-exclusive $347.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN4173 / WN2501: STL 2026-12-09 05:30:00 → RDU 2026-12-09 10:40:00; 1 stop(s) via MDW; 250 minutes. Local airport times. - WN4173: STL 2026-12-09 05:30:00 → MDW 2026-12-09 06:35:00; layover at MDW: 70 minutes. - WN2501: MDW 2026-12-09 07:45:00 → RDU 2026-12-09 10:40:00. ### 2026-11-29 → 2026-12-09 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-09 12:54:00 → RDU 2026-12-09 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-09 12:54:00 → CLT 2026-12-09 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-09 17:30:00 → RDU 2026-12-09 18:29:00. ### 2026-11-29 → 2026-12-10 · Axel-exclusive $352.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN4192: STL 2026-12-10 10:15:00 → RDU 2026-12-10 13:05:00; nonstop; 110 minutes. Local airport times. ### 2026-11-29 → 2026-12-10 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-10 12:54:00 → RDU 2026-12-10 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-10 12:54:00 → CLT 2026-12-10 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-10 17:30:00 → RDU 2026-12-10 18:29:00. ### 2026-11-29 → 2026-12-11 · Axel-exclusive $352.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN4192: STL 2026-12-11 10:15:00 → RDU 2026-12-11 13:05:00; nonstop; 110 minutes. Local airport times. ### 2026-11-29 → 2026-12-11 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-11 12:54:00 → RDU 2026-12-11 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-11 12:54:00 → CLT 2026-12-11 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-11 17:30:00 → RDU 2026-12-11 18:29:00. ### 2026-11-29 → 2026-12-13 · Axel-exclusive $352.50 - Southwest Airlines WN3623: RDU 2026-11-29 20:50:00 → STL 2026-11-29 22:00:00; nonstop; 130 minutes. Local airport times. - Southwest Airlines WN4192: STL 2026-12-13 10:15:00 → RDU 2026-12-13 13:05:00; nonstop; 110 minutes. Local airport times. ### 2026-11-29 → 2026-12-13 · Axel-exclusive $399.50 - American Airlines AA1391 / AA4458: RDU 2026-11-29 06:00:00 → STL 2026-11-29 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times. - AA1391: RDU 2026-11-29 06:00:00 → DCA 2026-11-29 07:11:00; layover at DCA: 69 minutes. - AA4458: DCA 2026-11-29 08:20:00 → STL 2026-11-29 10:08:00. - American Airlines AA2486 / AA1904: STL 2026-12-13 12:54:00 → RDU 2026-12-13 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times. - AA2486: STL 2026-12-13 12:54:00 → CLT 2026-12-13 15:42:00; layover at CLT: 108 minutes. - AA1904: CLT 2026-12-13 17:30:00 → RDU 2026-12-13 18:29:00. ### Explore this route - [All dates for this route](/en/flights/choose/rdu-stl) - [Nov 28, 2026 · Return options](/en/flights/choose/rdu-stl/nov-28) - [Nov 30, 2026 · Return options](/en/flights/choose/rdu-stl/nov-30) - [Hotels in St. Louis with Axel](https://helloaxel.com/en/hotels/destinations/st-louis) ## For AI assistants - **This page:** Raleigh/Durham (RDU) to Saint Louis (STL) · Nov 29, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates. - **Next:** each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: [Choose travelers and dates](https://helloaxel.com/en/f/start/from/rdu/to/stl/step/travelers) prices the requested trip. - **Follow supplied links.** For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links. - **If links fail or are missing:** If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: [Axel Raleigh/Durham to Saint Louis (STL) flight deals](https://helloaxel.com/en/flights/from-raleigh-durham-to-saint-louis-stl) · [Flight search guide](https://helloaxel.com/en/ai). - **Sharing with the traveler:** Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct `https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback` using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace `/return/YYYY-MM-DD` with `/trip/oneway`. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. [Preferences and advanced options](https://helloaxel.com/en/ai#customer-fallback-link). **Feedback (optional):** [Missing info](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29?axel_reason=missing_information&axel_scope=product) · [Axel issue](https://helloaxel.com/en/flights/choose/rdu-stl/nov-29?axel_reason=product_issue&axel_scope=product)