Raleigh/Durham (RDU) to Saint Louis (STL), Nov 11–14, 2026: from $300 round trip

Raleigh/Durham (RDU) to Saint Louis (STL), Nov 11–14, 2026: from $300 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $300 round trip, Axel-exclusive, Southwest Airlines, nonstop, Nov 11–14, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in St. Louis for these nights (Nov 11–14, 2026 · 3 nights · 2 adults, 1 room): 3★ Hampton Inn & Suites St. Louis at Forest Park · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis

All hotels in St. Louis

Route overview: Raleigh/Durham to Saint Louis (STL) flight deals

2026-11-11 → 2026-11-14 · Axel-exclusive $300.00

• Southwest Airlines WN3622: RDU 2026-11-11 06:05:00 → STL 2026-11-11 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4810: STL 2026-11-14 18:10:00 → RDU 2026-11-14 21:00:00; nonstop; 110 minutes. Local airport times.

2026-11-11 → 2026-11-14 · Axel-exclusive $340.00

• American Airlines AA638 / AA2486: RDU 2026-11-11 10:07:00 → STL 2026-11-11 13:18:00; 1 stop(s) via CLT; 251 minutes. Local airport times.
  • AA638: RDU 2026-11-11 10:07:00 → CLT 2026-11-11 11:17:00; layover at CLT: 63 minutes.
  • AA2486: CLT 2026-11-11 12:20:00 → STL 2026-11-11 13:18:00.
• American Airlines AA2486 / AA1904: STL 2026-11-14 12:54:00 → RDU 2026-11-14 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times.
  • AA2486: STL 2026-11-14 12:54:00 → CLT 2026-11-14 15:42:00; layover at CLT: 108 minutes.
  • AA1904: CLT 2026-11-14 17:30:00 → RDU 2026-11-14 18:29:00.

2026-11-11 → 2026-11-14 · Axel-exclusive $350.00

• United Airlines UA3704 / UA4427: RDU 2026-11-11 06:00:00 → STL 2026-11-11 10:12:00; 1 stop(s) via IAD; 312 minutes. Local airport times.
  • UA3704: RDU 2026-11-11 06:00:00 → IAD 2026-11-11 07:11:00; layover at IAD: 89 minutes.
  • UA4427: IAD 2026-11-11 08:40:00 → STL 2026-11-11 10:12:00.
• United Airlines UA3495 / UA2344: STL 2026-11-14 13:23:00 → RDU 2026-11-14 18:51:00; 1 stop(s) via IAD; 268 minutes. Local airport times.
  • UA3495: STL 2026-11-14 13:23:00 → IAD 2026-11-14 16:33:00; layover at IAD: 62 minutes.
  • UA2344: IAD 2026-11-14 17:35:00 → RDU 2026-11-14 18:51:00.

2026-11-11 → 2026-11-14 · Axel-exclusive $355.00

• Delta Air Lines DL2164 / DL2822: RDU 2026-11-11 12:56:00 → STL 2026-11-11 17:20:00; 1 stop(s) via DTW; 324 minutes. Local airport times.
  • DL2164: RDU 2026-11-11 12:56:00 → DTW 2026-11-11 14:49:00; layover at DTW: 104 minutes.
  • DL2822: DTW 2026-11-11 16:33:00 → STL 2026-11-11 17:20:00.
• Delta Air Lines DL1571 / DL2600: STL 2026-11-14 10:06:00 → RDU 2026-11-14 17:01:00; 1 stop(s) via ATL; 355 minutes. Local airport times.
  • DL1571: STL 2026-11-14 10:06:00 → ATL 2026-11-14 12:36:00; layover at ATL: 181 minutes.
  • DL2600: ATL 2026-11-14 15:37:00 → RDU 2026-11-14 17:01:00.

2026-11-11 → 2026-11-14 · Axel-exclusive $300.00

• Southwest Airlines WN1459: RDU 2026-11-11 18:20:00 → STL 2026-11-11 19:30:00; nonstop; 130 minutes. Local airport times.
• Southwest Airlines WN4810: STL 2026-11-14 18:10:00 → RDU 2026-11-14 21:00:00; nonstop; 110 minutes. Local airport times.

2026-11-11 → 2026-11-14 · Axel-exclusive $340.00

• American Airlines AA1391 / AA4458: RDU 2026-11-11 06:00:00 → STL 2026-11-11 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times.
  • AA1391: RDU 2026-11-11 06:00:00 → DCA 2026-11-11 07:11:00; layover at DCA: 69 minutes.
  • AA4458: DCA 2026-11-11 08:20:00 → STL 2026-11-11 10:08:00.
• American Airlines AA2486 / AA1904: STL 2026-11-14 12:54:00 → RDU 2026-11-14 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times.
  • AA2486: STL 2026-11-14 12:54:00 → CLT 2026-11-14 15:42:00; layover at CLT: 108 minutes.
  • AA1904: CLT 2026-11-14 17:30:00 → RDU 2026-11-14 18:29:00.

2026-11-11 → 2026-11-14 · Axel-exclusive $350.00

• United Airlines UA2638 / UA1857: RDU 2026-11-11 08:05:00 → STL 2026-11-11 12:22:00; 1 stop(s) via ORD; 317 minutes. Local airport times.
  • UA2638: RDU 2026-11-11 08:05:00 → ORD 2026-11-11 09:30:00; layover at ORD: 82 minutes.
  • UA1857: ORD 2026-11-11 10:52:00 → STL 2026-11-11 12:22:00.
• United Airlines UA3495 / UA2344: STL 2026-11-14 13:23:00 → RDU 2026-11-14 18:51:00; 1 stop(s) via IAD; 268 minutes. Local airport times.
  • UA3495: STL 2026-11-14 13:23:00 → IAD 2026-11-14 16:33:00; layover at IAD: 62 minutes.
  • UA2344: IAD 2026-11-14 17:35:00 → RDU 2026-11-14 18:51:00.

2026-11-11 → 2026-11-14 · Axel-exclusive $355.00

• Delta Air Lines DL2478 / DL1400: RDU 2026-11-11 08:00:00 → STL 2026-11-11 11:29:00; 1 stop(s) via ATL; 269 minutes. Local airport times.
  • DL2478: RDU 2026-11-11 08:00:00 → ATL 2026-11-11 09:40:00; layover at ATL: 60 minutes.
  • DL1400: ATL 2026-11-11 10:40:00 → STL 2026-11-11 11:29:00.
• Delta Air Lines DL1571 / DL2600: STL 2026-11-14 10:06:00 → RDU 2026-11-14 17:01:00; 1 stop(s) via ATL; 355 minutes. Local airport times.
  • DL1571: STL 2026-11-14 10:06:00 → ATL 2026-11-14 12:36:00; layover at ATL: 181 minutes.
  • DL2600: ATL 2026-11-14 15:37:00 → RDU 2026-11-14 17:01:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 10, 2026 · Return options
• Nov 12, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Raleigh/Durham (RDU) to Saint Louis (STL) · Nov 11, 2026 · return Nov 14, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
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