Raleigh/Durham (RDU) to Saint Louis (STL) · Jan 25, 2027 · return Feb 8, 2027

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in St. Louis for these nights (Jan 25 – Feb 8, 2027 · 14 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $1,065 total · 4★ The Westin St. Louis, $1,773 total · 5★ Four Seasons Hotel St Louis, $4,006 total

All hotels in St. Louis

Route overview: Raleigh/Durham to Saint Louis (STL) flight deals

2027-01-25 → 2027-02-08 · Axel-exclusive $300.00

• Southwest Airlines WN3623: RDU 2027-01-25 20:50:00 → STL 2027-01-25 22:00:00; nonstop; 130 minutes. Local airport times.
• Southwest Airlines WN4192: STL 2027-02-08 10:15:00 → RDU 2027-02-08 13:05:00; nonstop; 110 minutes. Local airport times.

2027-01-25 → 2027-02-08 · Axel-exclusive $340.00

• American Airlines AA1391 / AA4458: RDU 2027-01-25 06:00:00 → STL 2027-01-25 10:08:00; 1 stop(s) via DCA; 308 minutes. Local airport times.
  • AA1391: RDU 2027-01-25 06:00:00 → DCA 2027-01-25 07:11:00; layover at DCA: 69 minutes.
  • AA4458: DCA 2027-01-25 08:20:00 → STL 2027-01-25 10:08:00.
• American Airlines AA2486 / AA1904: STL 2027-02-08 12:54:00 → RDU 2027-02-08 18:29:00; 1 stop(s) via CLT; 275 minutes. Local airport times.
  • AA2486: STL 2027-02-08 12:54:00 → CLT 2027-02-08 15:42:00; layover at CLT: 108 minutes.
  • AA1904: CLT 2027-02-08 17:30:00 → RDU 2027-02-08 18:29:00.

2027-01-25 → 2027-02-08 · Axel-exclusive $350.00

• United Airlines UA3704 / UA4427: RDU 2027-01-25 06:00:00 → STL 2027-01-25 10:12:00; 1 stop(s) via IAD; 312 minutes. Local airport times.
  • UA3704: RDU 2027-01-25 06:00:00 → IAD 2027-01-25 07:11:00; layover at IAD: 89 minutes.
  • UA4427: IAD 2027-01-25 08:40:00 → STL 2027-01-25 10:12:00.
• United Airlines UA3495 / UA2344: STL 2027-02-08 13:23:00 → RDU 2027-02-08 18:51:00; 1 stop(s) via IAD; 268 minutes. Local airport times.
  • UA3495: STL 2027-02-08 13:23:00 → IAD 2027-02-08 16:33:00; layover at IAD: 62 minutes.
  • UA2344: IAD 2027-02-08 17:35:00 → RDU 2027-02-08 18:51:00.

2027-01-25 → 2027-02-08 · Axel-exclusive $355.00

• Delta Air Lines DL2164 / DL2822: RDU 2027-01-25 12:56:00 → STL 2027-01-25 17:20:00; 1 stop(s) via DTW; 324 minutes. Local airport times.
  • DL2164: RDU 2027-01-25 12:56:00 → DTW 2027-01-25 14:49:00; layover at DTW: 104 minutes.
  • DL2822: DTW 2027-01-25 16:33:00 → STL 2027-01-25 17:20:00.
• Delta Air Lines DL1571 / DL2600: STL 2027-02-08 10:06:00 → RDU 2027-02-08 17:01:00; 1 stop(s) via ATL; 355 minutes. Local airport times.
  • DL1571: STL 2027-02-08 10:06:00 → ATL 2027-02-08 12:36:00; layover at ATL: 181 minutes.
  • DL2600: ATL 2027-02-08 15:37:00 → RDU 2027-02-08 17:01:00.

2027-01-25 → 2027-02-08 · Axel-exclusive $295.00

• Southwest Airlines WN3623: RDU 2027-01-25 19:50:00 → STL 2027-01-25 21:00:00; nonstop; 130 minutes. Local airport times.
• Southwest Airlines WN665 / WN4766: STL 2027-02-08 10:35:00 → RDU 2027-02-08 16:35:00; 1 stop(s) via BNA; 300 minutes. Local airport times.
  • WN665: STL 2027-02-08 10:35:00 → BNA 2027-02-08 11:40:00; layover at BNA: 145 minutes.
  • WN4766: BNA 2027-02-08 14:05:00 → RDU 2027-02-08 16:35:00.

2027-01-25 → 2027-02-08 · Axel-exclusive $350.00

• United Airlines UA2638 / UA1857: RDU 2027-01-25 08:05:00 → STL 2027-01-25 12:22:00; 1 stop(s) via ORD; 317 minutes. Local airport times.
  • UA2638: RDU 2027-01-25 08:05:00 → ORD 2027-01-25 09:30:00; layover at ORD: 82 minutes.
  • UA1857: ORD 2027-01-25 10:52:00 → STL 2027-01-25 12:22:00.
• United Airlines UA3495 / UA2344: STL 2027-02-08 13:23:00 → RDU 2027-02-08 18:51:00; 1 stop(s) via IAD; 268 minutes. Local airport times.
  • UA3495: STL 2027-02-08 13:23:00 → IAD 2027-02-08 16:33:00; layover at IAD: 62 minutes.
  • UA2344: IAD 2027-02-08 17:35:00 → RDU 2027-02-08 18:51:00.

2027-01-25 → 2027-02-08 · Axel-exclusive $355.00

• Delta Air Lines DL2478 / DL1400: RDU 2027-01-25 08:00:00 → STL 2027-01-25 11:29:00; 1 stop(s) via ATL; 269 minutes. Local airport times.
  • DL2478: RDU 2027-01-25 08:00:00 → ATL 2027-01-25 09:40:00; layover at ATL: 60 minutes.
  • DL1400: ATL 2027-01-25 10:40:00 → STL 2027-01-25 11:29:00.
• Delta Air Lines DL1571 / DL2600: STL 2027-02-08 10:06:00 → RDU 2027-02-08 17:01:00; 1 stop(s) via ATL; 355 minutes. Local airport times.
  • DL1571: STL 2027-02-08 10:06:00 → ATL 2027-02-08 12:36:00; layover at ATL: 181 minutes.
  • DL2600: ATL 2027-02-08 15:37:00 → RDU 2027-02-08 17:01:00.

Explore this route

• All dates for this route
• Jan 24, 2027 · Return options
• Jan 26, 2027 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Raleigh/Durham (RDU) to Saint Louis (STL) · Jan 25, 2027 · return Feb 8, 2027: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
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