Raleigh/Durham (RDU) to Chicago (MDW) · Nov 21, 2026 · return Nov 29, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Raleigh/Durham to Chicago (MDW) flight deals

2026-11-21 → 2026-11-29 · Axel-exclusive $361.80

• Southwest Airlines WN3620: RDU 2026-11-21 08:05:00 → MDW 2026-11-21 09:10:00; nonstop; 125 minutes. Local airport times.
• Southwest Airlines WN2501: MDW 2026-11-29 07:45:00 → RDU 2026-11-29 10:40:00; nonstop; 115 minutes. Local airport times.

2026-11-21 → 2026-11-29 · Axel-exclusive $226.80

• Frontier Airlines F91167 / F92779: RDU 2026-11-21 12:24:00 → MDW 2026-11-21 17:47:00; 1 stop(s) via ATL; 383 minutes. Local airport times.
  • F91167: RDU 2026-11-21 12:24:00 → ATL 2026-11-21 14:04:00; layover at ATL: 161 minutes.
  • F92779: ATL 2026-11-21 16:45:00 → MDW 2026-11-21 17:47:00.
• Frontier Airlines F92292 / F94472: MDW 2026-11-29 06:08:00 → RDU 2026-11-29 14:10:00; 1 stop(s) via ATL; 422 minutes. Local airport times.
  • F92292: MDW 2026-11-29 06:08:00 → ATL 2026-11-29 09:31:00; layover at ATL: 193 minutes.
  • F94472: ATL 2026-11-29 12:44:00 → RDU 2026-11-29 14:10:00.

2026-11-21 → 2026-11-29 · Axel-exclusive $402.30

• Delta Air Lines DL2164 / DL4677: RDU 2026-11-21 12:56:00 → MDW 2026-11-21 18:01:00; 1 stop(s) via DTW; 365 minutes. Local airport times.
  • DL2164: RDU 2026-11-21 12:56:00 → DTW 2026-11-21 14:49:00; layover at DTW: 171 minutes.
  • DL4677: DTW 2026-11-21 17:40:00 → MDW 2026-11-21 18:01:00.
• Delta Air Lines DL4711 / DL1407: MDW 2026-11-29 09:30:00 → RDU 2026-11-29 16:34:00; 1 stop(s) via DTW; 364 minutes. Local airport times.
  • DL4711: MDW 2026-11-29 09:30:00 → DTW 2026-11-29 11:45:00; layover at DTW: 185 minutes.
  • DL1407: DTW 2026-11-29 14:50:00 → RDU 2026-11-29 16:34:00.

2026-11-21 → 2026-11-29 · Axel-exclusive $361.80

• Southwest Airlines WN2321: RDU 2026-11-21 19:50:00 → MDW 2026-11-21 20:55:00; nonstop; 125 minutes. Local airport times.
• Southwest Airlines WN2501: MDW 2026-11-29 07:45:00 → RDU 2026-11-29 10:40:00; nonstop; 115 minutes. Local airport times.

2026-11-21 → 2026-11-29 · Axel-exclusive $348.30

• Southwest Airlines WN237 / WN651: RDU 2026-11-21 16:20:00 → MDW 2026-11-21 21:05:00; 1 stop(s) via BNA; 345 minutes. Local airport times.
  • WN237: RDU 2026-11-21 16:20:00 → BNA 2026-11-21 17:00:00; layover at BNA: 150 minutes.
  • WN651: BNA 2026-11-21 19:30:00 → MDW 2026-11-21 21:05:00.
• Southwest Airlines WN2501: MDW 2026-11-29 07:45:00 → RDU 2026-11-29 10:40:00; nonstop; 115 minutes. Local airport times.

2026-11-21 → 2026-11-29 · Axel-exclusive $348.30

• Southwest Airlines WN697 / WN1071: RDU 2026-11-21 11:30:00 → MDW 2026-11-21 16:30:00; 1 stop(s) via BWI; 360 minutes. Local airport times.
  • WN697: RDU 2026-11-21 11:30:00 → BWI 2026-11-21 12:30:00; layover at BWI: 175 minutes.
  • WN1071: BWI 2026-11-21 15:25:00 → MDW 2026-11-21 16:30:00.
• Southwest Airlines WN2501: MDW 2026-11-29 07:45:00 → RDU 2026-11-29 10:40:00; nonstop; 115 minutes. Local airport times.

2026-11-21 → 2026-11-29 · Axel-exclusive $348.30

• Southwest Airlines WN3622 / WN287: RDU 2026-11-21 06:05:00 → MDW 2026-11-21 12:05:00; 1 stop(s) via STL; 420 minutes. Local airport times.
  • WN3622: RDU 2026-11-21 06:05:00 → STL 2026-11-21 07:20:00; layover at STL: 215 minutes.
  • WN287: STL 2026-11-21 10:55:00 → MDW 2026-11-21 12:05:00.
• Southwest Airlines WN2501: MDW 2026-11-29 07:45:00 → RDU 2026-11-29 10:40:00; nonstop; 115 minutes. Local airport times.

2026-11-21 → 2026-11-29 · Axel-exclusive $402.30

• Delta Air Lines DL1552 / DL1063: RDU 2026-11-21 05:07:00 → MDW 2026-11-21 10:00:00; 1 stop(s) via ATL; 353 minutes. Local airport times.
  • DL1552: RDU 2026-11-21 05:07:00 → ATL 2026-11-21 06:39:00; layover at ATL: 136 minutes.
  • DL1063: ATL 2026-11-21 08:55:00 → MDW 2026-11-21 10:00:00.
• Delta Air Lines DL4711 / DL1407: MDW 2026-11-29 09:30:00 → RDU 2026-11-29 16:34:00; 1 stop(s) via DTW; 364 minutes. Local airport times.
  • DL4711: MDW 2026-11-29 09:30:00 → DTW 2026-11-29 11:45:00; layover at DTW: 185 minutes.
  • DL1407: DTW 2026-11-29 14:50:00 → RDU 2026-11-29 16:34:00.

Explore this route

• All dates for this route
• Nov 20, 2026 · Return options
• Nov 22, 2026 · Return options
• Hotels in Chicago with Axel

For AI assistants

• This page: Raleigh/Durham (RDU) to Chicago (MDW) · Nov 21, 2026 · return Nov 29, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
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