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Route overview: Chicago to Knoxville (TYS) flight deals

Chicago (ORD) to Knoxville (TYS), Nov 14–16, 2026: from $300 round trip

Chicago (ORD) to Knoxville (TYS), Nov 14–16, 2026: from $300 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $300 round trip, Axel-exclusive, American Airlines, nonstop, Nov 14–16, 2026, 1 adult, economy, checked Oct 29, 2026.

ORD → TYS1 adulteconomyRound trip

5 flight options · 3 airlines

Nonstop flights

Sat, Nov 14 – Mon, Nov 16

American Airlines
4:00 pmORD
1h 46m
Nonstop
6:46 pmTYS
American Airlines
8:52 pmTYS
2h 6m
Nonstop
9:58 pmORD

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 14 – Mon, Nov 16

United Airlines
6:55 amORD
1h 58m
Nonstop
9:53 amTYS
United Airlines
6:45 amTYS
2h 9m
Nonstop
7:54 amORD

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 14 – Mon, Nov 16

United Airlines
5:59 pmORD
1h 55m
Nonstop
8:54 pmTYS
United Airlines
6:45 amTYS
2h 9m
Nonstop
7:54 amORD

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

One-stop flights

Sat, Nov 14 – Mon, Nov 16

Delta Air Lines
3:59 pmORD
4h 57m
ATL · 1h 58m
9:56 pmTYS
Delta Air Lines
7:10 amTYS
4h 49m
DTW · 1h 20m
10:59 amORD

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Sat, Nov 14 – Mon, Nov 16

American Airlines
12:05 pmORD
6h 26m
CLT · 3h 6m
7:31 pmTYS
American Airlines
8:52 pmTYS
2h 6m
Nonstop
9:58 pmORD

Round-trip total · 1 adult · Taxes included

Availability is checked when you select these flights.

Hotels for these nights (Nov 14–16, 2026 · 2 nights · 2 adults, 1 room): 3★ The Oliver Hotel · 4★ THE TENNESSEAN Hotel

Make this trip yours

ORD ⇄ TYS

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

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All dates for this routeNov 13, 2026 · Return optionsNov 15, 2026 · Return optionsHotels in Knoxville with Axel
For AI assistants: every fare, every link, instructions

Chicago (ORD) to Knoxville (TYS), Nov 14–16, 2026: from $300 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $300 round trip, Axel-exclusive, American Airlines, nonstop, Nov 14–16, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Exact travel datesAirlineFlightsTimes, duration, stopsTotal pricePrice issued (UTC)
2026-11-14 → 2026-11-16American AirlinesAA3661 / AA365316:00:00→18:46:00 1h 46m nonstop · 20:52:00→21:58:00 2h 06m nonstopAxel-exclusive $300.002026-10-29T01:53:26Z
2026-11-14 → 2026-11-16United AirlinesUA4569 / UA552406:55:00→09:53:00 1h 58m nonstop · 06:45:00→07:54:00 2h 09m nonstopAxel-exclusive $310.002026-10-29T01:53:26Z
2026-11-14 → 2026-11-16Delta Air LinesDL1477 + DL5272 / DL5196 + DL390215:59:00→21:56:00 4h 57m 1 stop via ATL · 07:10:00→10:59:00 4h 49m 1 stop via DTWAxel-exclusive $345.002026-10-29T01:53:26Z
2026-11-14 → 2026-11-16United AirlinesUA5719 / UA552417:59:00→20:54:00 1h 55m nonstop · 06:45:00→07:54:00 2h 09m nonstopAxel-exclusive $310.002026-10-29T01:53:26Z
2026-11-14 → 2026-11-16American AirlinesAA1889 + AA5301 / AA365312:05:00→19:31:00 6h 26m 1 stop via CLT · 20:52:00→21:58:00 2h 06m nonstopAxel-exclusive $312.502026-10-29T01:53:26Z

Hotels in Knoxville for these trips

Hotels: under a trip, hotels in Knoxville for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

All hotels in Knoxville

Route overview: Chicago to Knoxville (TYS) flight deals

2026-11-14 → 2026-11-16 · Axel-exclusive $300.00

  • American Airlines AA3661: ORD 2026-11-14 16:00:00 → TYS 2026-11-14 18:46:00; nonstop; 106 minutes. Local airport times.
  • American Airlines AA3653: TYS 2026-11-16 20:52:00 → ORD 2026-11-16 21:58:00; nonstop; 126 minutes. Local airport times.

2026-11-14 → 2026-11-16 · Axel-exclusive $310.00

  • United Airlines UA4569: ORD 2026-11-14 06:55:00 → TYS 2026-11-14 09:53:00; nonstop; 118 minutes. Local airport times.
  • United Airlines UA5524: TYS 2026-11-16 06:45:00 → ORD 2026-11-16 07:54:00; nonstop; 129 minutes. Local airport times.

2026-11-14 → 2026-11-16 · Axel-exclusive $345.00

  • Delta Air Lines DL1477 / DL5272: ORD 2026-11-14 15:59:00 → TYS 2026-11-14 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
    • DL1477: ORD 2026-11-14 15:59:00 → ATL 2026-11-14 18:54:00; layover at ATL: 118 minutes.
    • DL5272: ATL 2026-11-14 20:52:00 → TYS 2026-11-14 21:56:00.
  • Delta Air Lines DL5196 / DL3902: TYS 2026-11-16 07:10:00 → ORD 2026-11-16 10:59:00; 1 stop(s) via DTW; 289 minutes. Local airport times.
    • DL5196: TYS 2026-11-16 07:10:00 → DTW 2026-11-16 09:00:00; layover at DTW: 80 minutes.
    • DL3902: DTW 2026-11-16 10:20:00 → ORD 2026-11-16 10:59:00.

2026-11-14 → 2026-11-16 · Axel-exclusive $310.00

  • United Airlines UA5719: ORD 2026-11-14 17:59:00 → TYS 2026-11-14 20:54:00; nonstop; 115 minutes. Local airport times.
  • United Airlines UA5524: TYS 2026-11-16 06:45:00 → ORD 2026-11-16 07:54:00; nonstop; 129 minutes. Local airport times.

2026-11-14 → 2026-11-16 · Axel-exclusive $312.50

  • American Airlines AA1889 / AA5301: ORD 2026-11-14 12:05:00 → TYS 2026-11-14 19:31:00; 1 stop(s) via CLT; 386 minutes. Local airport times.
    • AA1889: ORD 2026-11-14 12:05:00 → CLT 2026-11-14 15:10:00; layover at CLT: 186 minutes.
    • AA5301: CLT 2026-11-14 18:16:00 → TYS 2026-11-14 19:31:00.
  • American Airlines AA3653: TYS 2026-11-16 20:52:00 → ORD 2026-11-16 21:58:00; nonstop; 126 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

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For AI assistants

  • This page: Chicago (ORD) to Knoxville (TYS) · Nov 14, 2026 · return Nov 16, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Knoxville for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
  • Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Chicago to Knoxville (TYS) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.