Chicago (ORD) to Knoxville (TYS), Nov 10, 2026: from $165 one way

Chicago (ORD) to Knoxville (TYS), Nov 10, 2026: from $165 one way on Axel, checked Oct 29, 2026. Lowest published fare: $165 one way, Axel-exclusive, American Airlines, nonstop, Nov 10, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Chicago to Knoxville (TYS) flight deals

2026-11-10 · one way · Axel-exclusive $165.00

• American Airlines AA3661: ORD 2026-11-10 16:00:00 → TYS 2026-11-10 18:46:00; nonstop; 106 minutes. Local airport times.

2026-11-10 · one way · Axel-exclusive $170.00

• United Airlines UA4559: ORD 2026-11-10 10:25:00 → TYS 2026-11-10 13:13:00; nonstop; 108 minutes. Local airport times.

2026-11-10 · one way · Axel-exclusive $190.00

• Delta Air Lines DL1477 / DL5272: ORD 2026-11-10 15:59:00 → TYS 2026-11-10 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
  • DL1477: ORD 2026-11-10 15:59:00 → ATL 2026-11-10 18:54:00; layover at ATL: 118 minutes.
  • DL5272: ATL 2026-11-10 20:52:00 → TYS 2026-11-10 21:56:00.

2026-11-10 · one way · Axel-exclusive $170.00

• United Airlines UA5719: ORD 2026-11-10 17:59:00 → TYS 2026-11-10 20:54:00; nonstop; 115 minutes. Local airport times.

2026-11-10 · one way · Axel-exclusive $180.00

• American Airlines AA1889 / AA5301: ORD 2026-11-10 12:05:00 → TYS 2026-11-10 19:31:00; 1 stop(s) via CLT; 386 minutes. Local airport times.
  • AA1889: ORD 2026-11-10 12:05:00 → CLT 2026-11-10 15:10:00; layover at CLT: 186 minutes.
  • AA5301: CLT 2026-11-10 18:16:00 → TYS 2026-11-10 19:31:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 9, 2026 · Return options
• Nov 11, 2026 · Return options
• Hotels in Knoxville with Axel

For AI assistants

• This page: Chicago (ORD) to Knoxville (TYS) · Nov 10, 2026 · one way: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
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