Chicago (ORD) to Knoxville (TYS) · Dec 17, 2026 · return Dec 21, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Knoxville for these trips

Hotels: under a trip, hotels in Knoxville for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in Knoxville for these nights (Dec 17–21, 2026 · 4 nights · 2 adults, 1 room): 3★ Holiday Inn Knoxville N - Merchant Drive by IHG, $386 total · 4★ Graduate by Hilton Knoxville, $2,742 total

All hotels in Knoxville

Route overview: Chicago to Knoxville (TYS) flight deals

2026-12-17 → 2026-12-21 · Axel-exclusive $345.00

• American Airlines AA3661: ORD 2026-12-17 16:00:00 → TYS 2026-12-17 18:46:00; nonstop; 106 minutes. Local airport times.
• American Airlines AA3653: TYS 2026-12-21 20:52:00 → ORD 2026-12-21 21:58:00; nonstop; 126 minutes. Local airport times.

2026-12-17 → 2026-12-21 · Axel-exclusive $356.50

• United Airlines UA5693: ORD 2026-12-17 14:10:00 → TYS 2026-12-17 17:00:00; nonstop; 110 minutes. Local airport times.
• United Airlines UA5921: TYS 2026-12-21 10:57:00 → ORD 2026-12-21 11:59:00; nonstop; 122 minutes. Local airport times.

2026-12-17 → 2026-12-21 · Axel-exclusive $396.75

• Delta Air Lines DL1477 / DL5272: ORD 2026-12-17 15:59:00 → TYS 2026-12-17 21:56:00; 1 stop(s) via ATL; 297 minutes. Local airport times.
  • DL1477: ORD 2026-12-17 15:59:00 → ATL 2026-12-17 18:54:00; layover at ATL: 118 minutes.
  • DL5272: ATL 2026-12-17 20:52:00 → TYS 2026-12-17 21:56:00.
• Delta Air Lines DL1743 / DL2738: TYS 2026-12-21 12:32:00 → ORD 2026-12-21 17:06:00; 1 stop(s) via ATL; 334 minutes. Local airport times.
  • DL1743: TYS 2026-12-21 12:32:00 → ATL 2026-12-21 13:38:00; layover at ATL: 132 minutes.
  • DL2738: ATL 2026-12-21 15:50:00 → ORD 2026-12-21 17:06:00.

2026-12-17 → 2026-12-21 · Axel-exclusive $356.50

• United Airlines UA5726: ORD 2026-12-17 07:15:00 → TYS 2026-12-17 10:10:00; nonstop; 115 minutes. Local airport times.
• United Airlines UA5921: TYS 2026-12-21 10:57:00 → ORD 2026-12-21 11:59:00; nonstop; 122 minutes. Local airport times.

2026-12-17 → 2026-12-21 · Axel-exclusive $357.50

• American Airlines AA1889 / AA5301: ORD 2026-12-17 12:05:00 → TYS 2026-12-17 19:31:00; 1 stop(s) via CLT; 386 minutes. Local airport times.
  • AA1889: ORD 2026-12-17 12:05:00 → CLT 2026-12-17 15:10:00; layover at CLT: 186 minutes.
  • AA5301: CLT 2026-12-17 18:16:00 → TYS 2026-12-17 19:31:00.
• American Airlines AA3653: TYS 2026-12-21 20:52:00 → ORD 2026-12-21 21:58:00; nonstop; 126 minutes. Local airport times.

Explore this route

• All dates for this route
• Dec 16, 2026 · Return options
• Dec 18, 2026 · Return options
• Hotels in Knoxville with Axel

For AI assistants

• This page: Chicago (ORD) to Knoxville (TYS) · Dec 17, 2026 · return Dec 21, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Knoxville for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
• Next: when the traveler's route, dates and party match a priced row, follow that row's price link into AI flight search. Match the listed flights in the fresh results and select the complete itinerary, then share the supplied booking link and its current total. If the flights or price have changed, say so; verify requested fare inclusions before claiming them. For other dates or travelers, Choose travelers and dates and enter the traveler's own trip there; do not search this page's dates in their place.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Chicago to Knoxville (TYS) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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