Chicago (ORD) to Panama City (PTY), Nov 25–28, 2026: from $637 round trip

Chicago (ORD) to Panama City (PTY), Nov 25–28, 2026: from $637 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $637 round trip, Axel-exclusive, American Airlines, 1 stop, Nov 25–28, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Panama City for these trips

Hotels: under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Panama City for these nights (Nov 25–28, 2026 · 3 nights · 2 adults, 1 room): 3★ Plaza Paitilla Inn Hotel · 4★ Novotel Panama City · 5★ Sofitel Legend Casco Viejo, Panama City

All hotels in Panama City

Route overview: Chicago to Panama City (PTY) flight deals

2026-11-25 → 2026-11-28 · Axel-exclusive $731.60

• Copa Airlines CM229: ORD 2026-11-25 14:17:00 → PTY 2026-11-25 20:41:00; nonstop; 324 minutes. Local airport times.
• Copa Airlines CM235: PTY 2026-11-28 19:28:00 → ORD 2026-11-29 00:11:00; nonstop; 343 minutes. Local airport times.

2026-11-25 → 2026-11-28 · Axel-exclusive $637.20

• American Airlines AA2984 / AA315: ORD 2026-11-25 05:00:00 → PTY 2026-11-25 14:13:00; 1 stop(s) via MIA; 493 minutes. Local airport times.
  • AA2984: ORD 2026-11-25 05:00:00 → MIA 2026-11-25 09:15:00; layover at MIA: 105 minutes.
  • AA315: MIA 2026-11-25 11:00:00 → PTY 2026-11-25 14:13:00.
• American Airlines AA1652 / AA3148: PTY 2026-11-28 16:33:00 → ORD 2026-11-29 00:33:00; 1 stop(s) via MIA; 540 minutes. Local airport times.
  • AA1652: PTY 2026-11-28 16:33:00 → MIA 2026-11-28 19:48:00; layover at MIA: 126 minutes.
  • AA3148: MIA 2026-11-28 21:54:00 → ORD 2026-11-29 00:33:00.

2026-11-25 → 2026-11-28 · Axel-exclusive $696.20

• United Airlines UA535 / UA1034: ORD 2026-11-25 09:21:00 → PTY 2026-11-25 19:38:00; 1 stop(s) via IAH; 557 minutes. Local airport times.
  • UA535: ORD 2026-11-25 09:21:00 → IAH 2026-11-25 12:24:00; layover at IAH: 123 minutes.
  • UA1034: IAH 2026-11-25 14:27:00 → PTY 2026-11-25 19:38:00.
• Copa Airlines CM235: PTY 2026-11-28 19:28:00 → ORD 2026-11-29 00:11:00; nonstop; 343 minutes. Local airport times.

2026-11-25 → 2026-11-28 · Axel-exclusive $731.60

• Copa Airlines CM236: ORD 2026-11-25 07:35:00 → PTY 2026-11-25 14:01:00; nonstop; 326 minutes. Local airport times.
• Copa Airlines CM235: PTY 2026-11-28 19:28:00 → ORD 2026-11-29 00:11:00; nonstop; 343 minutes. Local airport times.

2026-11-25 → 2026-11-28 · Axel-exclusive $696.20

• United Airlines UA2616 / CM467: ORD 2026-11-25 10:32:00 → PTY 2026-11-25 19:39:00; 1 stop(s) via RDU; 487 minutes. Local airport times.
  • UA2616: ORD 2026-11-25 10:32:00 → RDU 2026-11-25 13:44:00; layover at RDU: 82 minutes.
  • CM467: RDU 2026-11-25 15:06:00 → PTY 2026-11-25 19:39:00.
• Copa Airlines CM235: PTY 2026-11-28 19:28:00 → ORD 2026-11-29 00:11:00; nonstop; 343 minutes. Local airport times.

2026-11-25 → 2026-11-28 · Axel-exclusive $696.20

• United Airlines UA2280 / CM479: ORD 2026-11-25 07:05:00 → PTY 2026-11-25 17:08:00; 1 stop(s) via MCO; 543 minutes. Local airport times.
  • UA2280: ORD 2026-11-25 07:05:00 → MCO 2026-11-25 10:56:00; layover at MCO: 163 minutes.
  • CM479: MCO 2026-11-25 13:39:00 → PTY 2026-11-25 17:08:00.
• Copa Airlines CM235: PTY 2026-11-28 19:28:00 → ORD 2026-11-29 00:11:00; nonstop; 343 minutes. Local airport times.

2026-11-25 → 2026-11-28 · Axel-exclusive $696.20

• United Airlines UA1358 / CM481: ORD 2026-11-25 07:00:00 → PTY 2026-11-25 16:01:00; 1 stop(s) via MIA; 481 minutes. Local airport times.
  • UA1358: ORD 2026-11-25 07:00:00 → MIA 2026-11-25 11:11:00; layover at MIA: 93 minutes.
  • CM481: MIA 2026-11-25 12:44:00 → PTY 2026-11-25 16:01:00.
• Copa Airlines CM235: PTY 2026-11-28 19:28:00 → ORD 2026-11-29 00:11:00; nonstop; 343 minutes. Local airport times.

2026-11-25 → 2026-11-28 · Axel-exclusive $696.20

• United Airlines UA2684 / CM891: ORD 2026-11-25 10:41:00 → PTY 2026-11-25 20:31:00; 1 stop(s) via ATL; 530 minutes. Local airport times.
  • UA2684: ORD 2026-11-25 10:41:00 → ATL 2026-11-25 13:48:00; layover at ATL: 152 minutes.
  • CM891: ATL 2026-11-25 16:20:00 → PTY 2026-11-25 20:31:00.
• Copa Airlines CM235: PTY 2026-11-28 19:28:00 → ORD 2026-11-29 00:11:00; nonstop; 343 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 24, 2026 · Return options
• Nov 26, 2026 · Return options
• Hotels in Panama City with Axel

For AI assistants

• This page: Chicago (ORD) to Panama City (PTY) · Nov 25, 2026 · return Nov 28, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Panama City for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
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