Chicago (ORD) to Madrid (MAD), Mar 21, 2027: from $516 one way

Chicago (ORD) to Madrid (MAD), Mar 21, 2027: from $516 one way on Axel, checked Nov 14, 2026. Lowest published fare: $516 one way, Axel-exclusive, TAP Air Portugal, 1 stop, Mar 21, 2027, 1 adult, economy, checked Nov 14, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Chicago to Madrid (MAD) flight deals

2027-03-21 · one way · Axel-exclusive $624

• Iberia IB342: ORD 2027-03-21 17:40:00 → MAD 2027-03-22 07:50:00; nonstop; 490 minutes. Local airport times.

2027-03-21 · one way · Axel-exclusive $660

• American Airlines AA126: ORD 2027-03-21 18:10:00 → MAD 2027-03-22 08:25:00; nonstop; 495 minutes. Local airport times.

2027-03-21 · one way · Axel-exclusive $516

• TAP Air Portugal TP244 / TP1014: ORD 2027-03-21 20:10:00 → MAD 2027-03-22 13:05:00; 1 stop(s) via LIS; 655 minutes. Local airport times.
  • TP244: ORD 2027-03-21 20:10:00 → LIS 2027-03-22 09:15:00; layover at LIS: 90 minutes.
  • TP1014: LIS 2027-03-22 10:45:00 → MAD 2027-03-22 13:05:00.

2027-03-21 · one way · Axel-exclusive $576

• Air Canada AC8482 / AC834: ORD 2027-03-21 13:55:00 → MAD 2027-03-22 07:00:00; 1 stop(s) via YUL; 665 minutes. Local airport times.
  • AC8482: ORD 2027-03-21 13:55:00 → YUL 2027-03-21 17:07:00; layover at YUL: 103 minutes.
  • AC834: YUL 2027-03-21 18:50:00 → MAD 2027-03-22 07:00:00.

2027-03-21 · one way · Axel-exclusive $612

• United Airlines UA1128 / UA260: ORD 2027-03-21 13:00:00 → MAD 2027-03-22 06:45:00; 1 stop(s) via IAD; 705 minutes. Local airport times.
  • UA1128: ORD 2027-03-21 13:00:00 → IAD 2027-03-21 16:03:00; layover at IAD: 127 minutes.
  • UA260: IAD 2027-03-21 18:10:00 → MAD 2027-03-22 06:45:00.

2027-03-21 · one way · Axel-exclusive $624

• Delta Air Lines DL5035 / DL126: ORD 2027-03-21 13:35:00 → MAD 2027-03-22 06:20:00; 1 stop(s) via JFK; 645 minutes. Local airport times.
  • DL5035: ORD 2027-03-21 13:35:00 → JFK 2027-03-21 16:57:00; layover at JFK: 78 minutes.
  • DL126: JFK 2027-03-21 18:15:00 → MAD 2027-03-22 06:20:00.

2027-03-21 · one way · Axel-exclusive $600

• American Airlines AA3113 / AA94: ORD 2027-03-21 14:31:00 → MAD 2027-03-22 07:50:00; 1 stop(s) via JFK; 679 minutes. Local airport times.
  • AA3113: ORD 2027-03-21 14:31:00 → JFK 2027-03-21 18:00:00; layover at JFK: 100 minutes.
  • AA94: JFK 2027-03-21 19:40:00 → MAD 2027-03-22 07:50:00.

2027-03-21 · one way · Axel-exclusive $600

• American Airlines AA3277 / AA748: ORD 2027-03-21 11:35:00 → MAD 2027-03-22 04:45:00; 1 stop(s) via CLT; 670 minutes. Local airport times.
  • AA3277: ORD 2027-03-21 11:35:00 → CLT 2027-03-21 14:47:00; layover at CLT: 78 minutes.
  • AA748: CLT 2027-03-21 16:05:00 → MAD 2027-03-22 04:45:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Mar 20, 2027 · Return options
• Mar 22, 2027 · Return options
• Hotels in Madrid with Axel

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