Myrtle Beach (MYR) to Detroit (DTW), Mar 21, 2027: from $173 one way

Myrtle Beach (MYR) to Detroit (DTW), Mar 21, 2027: from $173 one way on Axel, checked Nov 12, 2026. Lowest published fare: $173 one way, Axel-exclusive, Southwest Airlines, 1 stop, Mar 21, 2027, 1 adult, economy, checked Nov 12, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

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Route overview: Myrtle Beach to Detroit (DTW) flight deals

2027-03-21 · one way · Axel-exclusive $201.25

• Delta Air Lines DL1145: MYR 2027-03-21 11:26:00 → DTW 2027-03-21 13:30:00; nonstop; 124 minutes. Local airport times.

2027-03-21 · one way · Axel-exclusive $172.50

• Southwest Airlines WN1545 / WN4036: MYR 2027-03-21 15:25:00 → DTW 2027-03-21 22:10:00; 1 stop(s) via BWI; 405 minutes. Local airport times.
  • WN1545: MYR 2027-03-21 15:25:00 → BWI 2027-03-21 16:55:00; layover at BWI: 215 minutes.
  • WN4036: BWI 2027-03-21 20:30:00 → DTW 2027-03-21 22:10:00.

2027-03-21 · one way · Axel-exclusive $178.25

• American Airlines AA1709 / AA5550: MYR 2027-03-21 05:08:00 → DTW 2027-03-21 09:45:00; 1 stop(s) via CLT; 277 minutes. Local airport times.
  • AA1709: MYR 2027-03-21 05:08:00 → CLT 2027-03-21 06:15:00; layover at CLT: 87 minutes.
  • AA5550: CLT 2027-03-21 07:42:00 → DTW 2027-03-21 09:45:00.

2027-03-21 · one way · Axel-exclusive $189.75

• United Airlines UA3714 / UA1909: MYR 2027-03-21 18:10:00 → DTW 2027-03-21 23:59:00; 1 stop(s) via EWR; 349 minutes. Local airport times.
  • UA3714: MYR 2027-03-21 18:10:00 → EWR 2027-03-21 20:09:00; layover at EWR: 107 minutes.
  • UA1909: EWR 2027-03-21 21:56:00 → DTW 2027-03-21 23:59:00.

2027-03-21 · one way · Axel-exclusive $178.25

• American Airlines AA4809 / AA4712: MYR 2027-03-21 11:52:00 → DTW 2027-03-21 16:11:00; 1 stop(s) via DCA; 259 minutes. Local airport times.
  • AA4809: MYR 2027-03-21 11:52:00 → DCA 2027-03-21 13:19:00; layover at DCA: 62 minutes.
  • AA4712: DCA 2027-03-21 14:21:00 → DTW 2027-03-21 16:11:00.

2027-03-21 · one way · Axel-exclusive $178.25

• American Airlines AA5888 / AA5019: MYR 2027-03-21 13:56:00 → DTW 2027-03-21 20:44:00; 1 stop(s) via PHL; 408 minutes. Local airport times.
  • AA5888: MYR 2027-03-21 13:56:00 → PHL 2027-03-21 15:40:00; layover at PHL: 180 minutes.
  • AA5019: PHL 2027-03-21 18:40:00 → DTW 2027-03-21 20:44:00.

2027-03-21 · one way · Axel-exclusive $184.00

• Delta Air Lines DL3047 / DL1031: MYR 2027-03-21 10:52:00 → DTW 2027-03-21 16:05:00; 1 stop(s) via ATL; 313 minutes. Local airport times.
  • DL3047: MYR 2027-03-21 10:52:00 → ATL 2027-03-21 12:14:00; layover at ATL: 114 minutes.
  • DL1031: ATL 2027-03-21 14:08:00 → DTW 2027-03-21 16:05:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Mar 20, 2027 · Return options
• Mar 22, 2027 · Return options
• Hotels in Detroit with Axel

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