New Orleans (MSY) to Saint Louis (STL) · Nov 21, 2026 · return Nov 23, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in St. Louis for these nights (Nov 21–23, 2026 · 2 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $133 total · 4★ Hilton St. Louis at the Ballpark, $207 total · 5★ Four Seasons Hotel St Louis, $726 total

All hotels in St. Louis

Route overview: New Orleans to Saint Louis (STL) flight deals

2026-11-21 → 2026-11-23 · Axel-exclusive $280.00

• Southwest Airlines WN4792: MSY 2026-11-21 07:35:00 → STL 2026-11-21 09:25:00; nonstop; 110 minutes. Local airport times.
• Southwest Airlines WN4182: STL 2026-11-23 07:55:00 → MSY 2026-11-23 09:40:00; nonstop; 105 minutes. Local airport times.

2026-11-21 → 2026-11-23 · Axel-exclusive $325.00

• American Airlines AA1251 / AA2289: MSY 2026-11-21 18:28:00 → STL 2026-11-21 23:34:00; 1 stop(s) via DFW; 306 minutes. Local airport times.
  • AA1251: MSY 2026-11-21 18:28:00 → DFW 2026-11-21 20:30:00; layover at DFW: 75 minutes.
  • AA2289: DFW 2026-11-21 21:45:00 → STL 2026-11-21 23:34:00.
• American Airlines AA5082 / AA1007: STL 2026-11-23 12:58:00 → MSY 2026-11-23 19:34:00; 1 stop(s) via DFW; 396 minutes. Local airport times.
  • AA5082: STL 2026-11-23 12:58:00 → DFW 2026-11-23 15:05:00; layover at DFW: 179 minutes.
  • AA1007: DFW 2026-11-23 18:04:00 → MSY 2026-11-23 19:34:00.

2026-11-21 → 2026-11-23 · Axel-exclusive $335.00

• United Airlines UA2844 / UA2844: MSY 2026-11-21 07:00:00 → STL 2026-11-21 12:10:00; 1 stop(s) via ORD; 310 minutes. Local airport times.
  • UA2844: MSY 2026-11-21 07:00:00 → ORD 2026-11-21 09:38:00; layover at ORD: 67 minutes.
  • UA2844: ORD 2026-11-21 10:45:00 → STL 2026-11-21 12:10:00.
• United Airlines UA1371 / UA2393: STL 2026-11-23 06:00:00 → MSY 2026-11-23 10:56:00; 1 stop(s) via IAH; 296 minutes. Local airport times.
  • UA1371: STL 2026-11-23 06:00:00 → IAH 2026-11-23 08:21:00; layover at IAH: 78 minutes.
  • UA2393: IAH 2026-11-23 09:39:00 → MSY 2026-11-23 10:56:00.

2026-11-21 → 2026-11-23 · Axel-exclusive $345.00

• Delta Air Lines DL1534 / DL1400: MSY 2026-11-21 06:30:00 → STL 2026-11-21 11:15:00; 1 stop(s) via ATL; 285 minutes. Local airport times.
  • DL1534: MSY 2026-11-21 06:30:00 → ATL 2026-11-21 09:00:00; layover at ATL: 90 minutes.
  • DL1400: ATL 2026-11-21 10:30:00 → STL 2026-11-21 11:15:00.
• Delta Air Lines DL1393 / DL2224: STL 2026-11-23 19:18:00 → MSY 2026-11-23 23:59:00; 1 stop(s) via ATL; 281 minutes. Local airport times.
  • DL1393: STL 2026-11-23 19:18:00 → ATL 2026-11-23 21:59:00; layover at ATL: 81 minutes.
  • DL2224: ATL 2026-11-23 23:20:00 → MSY 2026-11-23 23:59:00.

2026-11-21 → 2026-11-23 · Axel-exclusive $270.00

• Southwest Airlines WN103 / WN261: MSY 2026-11-21 16:00:00 → STL 2026-11-21 21:00:00; 1 stop(s) via ATL; 300 minutes. Local airport times.
  • WN103: MSY 2026-11-21 16:00:00 → ATL 2026-11-21 18:25:00; layover at ATL: 110 minutes.
  • WN261: ATL 2026-11-21 20:15:00 → STL 2026-11-21 21:00:00.
• Southwest Airlines WN665 / WN667: STL 2026-11-23 10:35:00 → MSY 2026-11-23 16:30:00; 1 stop(s) via BNA; 355 minutes. Local airport times.
  • WN665: STL 2026-11-23 10:35:00 → BNA 2026-11-23 11:40:00; layover at BNA: 195 minutes.
  • WN667: BNA 2026-11-23 14:55:00 → MSY 2026-11-23 16:30:00.

2026-11-21 → 2026-11-23 · Axel-exclusive $270.00

• Southwest Airlines WN3121 / WN2715: MSY 2026-11-21 13:15:00 → STL 2026-11-21 19:10:00; 1 stop(s) via MCI; 355 minutes. Local airport times.
  • WN3121: MSY 2026-11-21 13:15:00 → MCI 2026-11-21 15:15:00; layover at MCI: 170 minutes.
  • WN2715: MCI 2026-11-21 18:05:00 → STL 2026-11-21 19:10:00.
• Southwest Airlines WN665 / WN667: STL 2026-11-23 10:35:00 → MSY 2026-11-23 16:30:00; 1 stop(s) via BNA; 355 minutes. Local airport times.
  • WN665: STL 2026-11-23 10:35:00 → BNA 2026-11-23 11:40:00; layover at BNA: 195 minutes.
  • WN667: BNA 2026-11-23 14:55:00 → MSY 2026-11-23 16:30:00.

2026-11-21 → 2026-11-23 · Axel-exclusive $275.00

• Southwest Airlines WN4792: MSY 2026-11-21 07:25:00 → STL 2026-11-21 09:10:00; nonstop; 105 minutes. Local airport times.
• Southwest Airlines WN665 / WN667: STL 2026-11-23 10:35:00 → MSY 2026-11-23 16:30:00; 1 stop(s) via BNA; 355 minutes. Local airport times.
  • WN665: STL 2026-11-23 10:35:00 → BNA 2026-11-23 11:40:00; layover at BNA: 195 minutes.
  • WN667: BNA 2026-11-23 14:55:00 → MSY 2026-11-23 16:30:00.

Explore this route

• All dates for this route
• Nov 20, 2026 · Return options
• Nov 22, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: New Orleans (MSY) to Saint Louis (STL) · Nov 21, 2026 · return Nov 23, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
• Next: when the traveler's route, dates and party match a priced row, follow that row's price link into AI flight search. Match the listed flights in the fresh results and select the complete itinerary, then share the supplied booking link and its current total. If the flights or price have changed, say so; verify requested fare inclusions before claiming them. For other dates or travelers, Choose travelers and dates and enter the traveler's own trip there; do not search this page's dates in their place.
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• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel New Orleans to Saint Louis (STL) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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