Minneapolis (MSP) to Knoxville (TYS) · Nov 30, 2026 · return Dec 6, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Knoxville for these trips

Hotels: under a trip, hotels in Knoxville for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in Knoxville for these nights (Nov 30 – Dec 6, 2026 · 6 nights · 2 adults, 1 room): 3★ Holiday Inn Knoxville N - Merchant Drive by IHG, $548 total · 4★ Graduate by Hilton Knoxville, $949 total

All hotels in Knoxville

Route overview: Minneapolis to Knoxville (TYS) flight deals

2026-11-30 → 2026-12-06 · Axel-exclusive $461.25

• Delta Air Lines DL5527: MSP 2026-11-30 19:59:00 → TYS 2026-11-30 23:24:00; nonstop; 145 minutes. Local airport times.
• Delta Air Lines DL5523: TYS 2026-12-06 07:59:00 → MSP 2026-12-06 09:40:00; nonstop; 161 minutes. Local airport times.

2026-11-30 → 2026-12-06 · Axel-exclusive $393.75

• American Airlines AA3099 / AA5577: MSP 2026-11-30 10:00:00 → TYS 2026-11-30 15:54:00; 1 stop(s) via CLT; 294 minutes. Local airport times.
  • AA3099: MSP 2026-11-30 10:00:00 → CLT 2026-11-30 13:37:00; layover at CLT: 64 minutes.
  • AA5577: CLT 2026-11-30 14:41:00 → TYS 2026-11-30 15:54:00.
• American Airlines AA5223 / AA3855: TYS 2026-12-06 18:26:00 → MSP 2026-12-06 23:35:00; 1 stop(s) via DCA; 369 minutes. Local airport times.
  • AA5223: TYS 2026-12-06 18:26:00 → DCA 2026-12-06 20:17:00; layover at DCA: 79 minutes.
  • AA3855: DCA 2026-12-06 21:36:00 → MSP 2026-12-06 23:35:00.

2026-11-30 → 2026-12-06 · Axel-exclusive $405.00

• United Airlines UA3579 / UA4914: MSP 2026-11-30 11:55:00 → TYS 2026-11-30 19:36:00; 1 stop(s) via IAD; 401 minutes. Local airport times.
  • UA3579: MSP 2026-11-30 11:55:00 → IAD 2026-11-30 15:26:00; layover at IAD: 139 minutes.
  • UA4914: IAD 2026-11-30 17:45:00 → TYS 2026-11-30 19:36:00.
• United Airlines UA4311 / UA3985: TYS 2026-12-06 05:45:00 → MSP 2026-12-06 10:36:00; 1 stop(s) via IAD; 351 minutes. Local airport times.
  • UA4311: TYS 2026-12-06 05:45:00 → IAD 2026-12-06 07:28:00; layover at IAD: 72 minutes.
  • UA3985: IAD 2026-12-06 08:40:00 → MSP 2026-12-06 10:36:00.

2026-11-30 → 2026-12-06 · Axel-exclusive $393.75

• American Airlines AA3483 / AA4229: MSP 2026-11-30 10:49:00 → TYS 2026-11-30 16:29:00; 1 stop(s) via ORD; 280 minutes. Local airport times.
  • AA3483: MSP 2026-11-30 10:49:00 → ORD 2026-11-30 12:35:00; layover at ORD: 70 minutes.
  • AA4229: ORD 2026-11-30 13:45:00 → TYS 2026-11-30 16:29:00.
• American Airlines AA5223 / AA3855: TYS 2026-12-06 18:26:00 → MSP 2026-12-06 23:35:00; 1 stop(s) via DCA; 369 minutes. Local airport times.
  • AA5223: TYS 2026-12-06 18:26:00 → DCA 2026-12-06 20:17:00; layover at DCA: 79 minutes.
  • AA3855: DCA 2026-12-06 21:36:00 → MSP 2026-12-06 23:35:00.

2026-11-30 → 2026-12-06 · Axel-exclusive $405.00

• United Airlines UA307 / UA4559: MSP 2026-11-30 06:00:00 → TYS 2026-11-30 13:13:00; 1 stop(s) via ORD; 373 minutes. Local airport times.
  • UA307: MSP 2026-11-30 06:00:00 → ORD 2026-11-30 07:42:00; layover at ORD: 163 minutes.
  • UA4559: ORD 2026-11-30 10:25:00 → TYS 2026-11-30 13:13:00.
• United Airlines UA4311 / UA3985: TYS 2026-12-06 05:45:00 → MSP 2026-12-06 10:36:00; 1 stop(s) via IAD; 351 minutes. Local airport times.
  • UA4311: TYS 2026-12-06 05:45:00 → IAD 2026-12-06 07:28:00; layover at IAD: 72 minutes.
  • UA3985: IAD 2026-12-06 08:40:00 → MSP 2026-12-06 10:36:00.

2026-11-30 → 2026-12-06 · Axel-exclusive $436.25

• Delta Air Lines DL1046 / DL4931: MSP 2026-11-30 10:15:00 → TYS 2026-11-30 15:57:00; 1 stop(s) via ATL; 282 minutes. Local airport times.
  • DL1046: MSP 2026-11-30 10:15:00 → ATL 2026-11-30 13:47:00; layover at ATL: 68 minutes.
  • DL4931: ATL 2026-11-30 14:55:00 → TYS 2026-11-30 15:57:00.
• Delta Air Lines DL5523: TYS 2026-12-06 07:59:00 → MSP 2026-12-06 09:40:00; nonstop; 161 minutes. Local airport times.

2026-11-30 → 2026-12-06 · Axel-exclusive $441.25

• Delta Air Lines DL5527: MSP 2026-11-30 19:55:00 → TYS 2026-11-30 23:11:00; nonstop; 136 minutes. Local airport times.
• Delta Air Lines DL4697 / DL1303: TYS 2026-12-06 17:10:00 → MSP 2026-12-06 20:57:00; 1 stop(s) via DTW; 287 minutes. Local airport times.
  • DL4697: TYS 2026-12-06 17:10:00 → DTW 2026-12-06 18:57:00; layover at DTW: 61 minutes.
  • DL1303: DTW 2026-12-06 19:58:00 → MSP 2026-12-06 20:57:00.

Explore this route

• All dates for this route
• Nov 29, 2026 · Return options
• Dec 1, 2026 · Return options
• Hotels in Knoxville with Axel

For AI assistants

• This page: Minneapolis (MSP) to Knoxville (TYS) · Nov 30, 2026 · return Dec 6, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Knoxville for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
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