Milwaukee (MKE) to Saint Louis (STL), Sep 24, 2027: round trips from $285, one way from $147

Milwaukee (MKE) to Saint Louis (STL), Sep 24, 2027: round trips from $285, one way from $147 on Axel, checked Nov 11, 2026. Lowest published fares: $285 round trip, Axel-exclusive, Southwest Airlines, nonstop, Sep 24–25, 2027; $147 one way, Axel-exclusive, Southwest Airlines, nonstop, Sep 24, 2027; 1 adult, economy, checked Nov 11, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in St. Louis for these nights (Sep 24–25, 2027 · 1 night · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24–26, 2027 · 2 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24–27, 2027 · 3 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24–28, 2027 · 4 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24–29, 2027 · 5 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24–30, 2027 · 6 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24 – Oct 1, 2027 · 7 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24 – Oct 2, 2027 · 8 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24 – Oct 3, 2027 · 9 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24 – Oct 4, 2027 · 10 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24 – Oct 5, 2027 · 11 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24 – Oct 6, 2027 · 12 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis
• Hotels in St. Louis for these nights (Sep 24 – Oct 7, 2027 · 13 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ Four Seasons Hotel St Louis

All hotels in St. Louis

Route overview: Milwaukee to Saint Louis (STL) flight deals

2027-09-24 · one way · Axel-exclusive $147.25

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.

2027-09-24 · one way · Axel-exclusive $180.50

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.

2027-09-24 → 2027-09-25 · Axel-exclusive $285.00

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4097: STL 2027-09-25 08:00:00 → MKE 2027-09-25 09:15:00; nonstop; 75 minutes. Local airport times.

2027-09-24 → 2027-09-25 · Axel-exclusive $342.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-09-25 05:25:00 → MKE 2027-09-25 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-09-25 05:25:00 → ORD 2027-09-25 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-09-25 10:25:00 → MKE 2027-09-25 11:28:00.

2027-09-24 → 2027-09-26 · Axel-exclusive $285.00

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4887: STL 2027-09-26 07:55:00 → MKE 2027-09-26 09:10:00; nonstop; 75 minutes. Local airport times.

2027-09-24 → 2027-09-26 · Axel-exclusive $342.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-09-26 05:25:00 → MKE 2027-09-26 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-09-26 05:25:00 → ORD 2027-09-26 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-09-26 10:25:00 → MKE 2027-09-26 11:28:00.

2027-09-24 → 2027-09-27 · Axel-exclusive $285.00

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4919: STL 2027-09-27 21:50:00 → MKE 2027-09-27 23:10:00; nonstop; 80 minutes. Local airport times.

2027-09-24 → 2027-09-27 · Axel-exclusive $342.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-09-27 05:25:00 → MKE 2027-09-27 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-09-27 05:25:00 → ORD 2027-09-27 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-09-27 10:25:00 → MKE 2027-09-27 11:28:00.

2027-09-24 → 2027-09-28 · Axel-exclusive $285.00

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN2589: STL 2027-09-28 08:30:00 → MKE 2027-09-28 09:40:00; nonstop; 70 minutes. Local airport times.

2027-09-24 → 2027-09-28 · Axel-exclusive $342.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-09-28 05:25:00 → MKE 2027-09-28 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-09-28 05:25:00 → ORD 2027-09-28 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-09-28 10:25:00 → MKE 2027-09-28 11:28:00.

2027-09-24 → 2027-09-29 · Axel-exclusive $285.00

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4097: STL 2027-09-29 08:00:00 → MKE 2027-09-29 09:15:00; nonstop; 75 minutes. Local airport times.

2027-09-24 → 2027-09-29 · Axel-exclusive $342.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-09-29 05:25:00 → MKE 2027-09-29 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-09-29 05:25:00 → ORD 2027-09-29 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-09-29 10:25:00 → MKE 2027-09-29 11:28:00.

2027-09-24 → 2027-10-01 · Axel-exclusive $292.50

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4097: STL 2027-10-01 08:00:00 → MKE 2027-10-01 09:15:00; nonstop; 75 minutes. Local airport times.

2027-09-24 → 2027-10-01 · Axel-exclusive $351.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-10-01 05:25:00 → MKE 2027-10-01 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-10-01 05:25:00 → ORD 2027-10-01 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-10-01 10:25:00 → MKE 2027-10-01 11:28:00.

2027-09-24 → 2027-10-02 · Axel-exclusive $292.50

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4097: STL 2027-10-02 08:00:00 → MKE 2027-10-02 09:15:00; nonstop; 75 minutes. Local airport times.

2027-09-24 → 2027-10-02 · Axel-exclusive $351.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-10-02 05:25:00 → MKE 2027-10-02 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-10-02 05:25:00 → ORD 2027-10-02 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-10-02 10:25:00 → MKE 2027-10-02 11:28:00.

2027-09-24 → 2027-10-03 · Axel-exclusive $292.50

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4887: STL 2027-10-03 07:55:00 → MKE 2027-10-03 09:10:00; nonstop; 75 minutes. Local airport times.

2027-09-24 → 2027-10-03 · Axel-exclusive $351.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-10-03 05:25:00 → MKE 2027-10-03 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-10-03 05:25:00 → ORD 2027-10-03 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-10-03 10:25:00 → MKE 2027-10-03 11:28:00.

2027-09-24 → 2027-10-04 · Axel-exclusive $292.50

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4919: STL 2027-10-04 21:50:00 → MKE 2027-10-04 23:10:00; nonstop; 80 minutes. Local airport times.

2027-09-24 → 2027-10-04 · Axel-exclusive $351.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-10-04 05:25:00 → MKE 2027-10-04 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-10-04 05:25:00 → ORD 2027-10-04 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-10-04 10:25:00 → MKE 2027-10-04 11:28:00.

2027-09-24 → 2027-10-05 · Axel-exclusive $292.50

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN2589: STL 2027-10-05 08:30:00 → MKE 2027-10-05 09:40:00; nonstop; 70 minutes. Local airport times.

2027-09-24 → 2027-10-05 · Axel-exclusive $351.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-10-05 05:25:00 → MKE 2027-10-05 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-10-05 05:25:00 → ORD 2027-10-05 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-10-05 10:25:00 → MKE 2027-10-05 11:28:00.

2027-09-24 → 2027-10-07 · Axel-exclusive $292.50

• Southwest Airlines WN1087: MKE 2027-09-24 17:50:00 → STL 2027-09-24 19:10:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4097: STL 2027-10-07 08:00:00 → MKE 2027-10-07 09:15:00; nonstop; 75 minutes. Local airport times.

2027-09-24 → 2027-10-07 · Axel-exclusive $351.00

• United Airlines UA5412 / UA1857: MKE 2027-09-24 07:45:00 → STL 2027-09-24 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-24 07:45:00 → ORD 2027-09-24 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-24 10:52:00 → STL 2027-09-24 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-10-07 05:25:00 → MKE 2027-10-07 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-10-07 05:25:00 → ORD 2027-10-07 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-10-07 10:25:00 → MKE 2027-10-07 11:28:00.

Explore this route

• All dates for this route
• Sep 23, 2027 · Return options
• Sep 25, 2027 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Milwaukee (MKE) to Saint Louis (STL) · Sep 24, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Milwaukee to Saint Louis (STL) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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