Milwaukee (MKE) to Saint Louis (STL), Sep 21, 2027: from $147 one way

Milwaukee (MKE) to Saint Louis (STL), Sep 21, 2027: from $147 one way on Axel, checked Nov 11, 2026. Lowest published fare: $147 one way, Axel-exclusive, Southwest Airlines, nonstop, Sep 21, 2027, 1 adult, economy, checked Nov 11, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Milwaukee to Saint Louis (STL) flight deals

2027-09-21 · one way · Axel-exclusive $147.25

• Southwest Airlines WN3112: MKE 2027-09-21 08:00:00 → STL 2027-09-21 09:30:00; nonstop; 90 minutes. Local airport times.

2027-09-21 · one way · Axel-exclusive $180.50

• United Airlines UA5412 / UA1857: MKE 2027-09-21 07:45:00 → STL 2027-09-21 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-21 07:45:00 → ORD 2027-09-21 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-21 10:52:00 → STL 2027-09-21 12:22:00.

2027-09-21 · one way · Axel-exclusive $185.25

• American Airlines AA4920 / AA4372: MKE 2027-09-21 14:51:00 → STL 2027-09-21 19:52:00; 1 stop(s) via ORD; 301 minutes. Local airport times.
  • AA4920: MKE 2027-09-21 14:51:00 → ORD 2027-09-21 16:12:00; layover at ORD: 127 minutes.
  • AA4372: ORD 2027-09-21 18:19:00 → STL 2027-09-21 19:52:00.

2027-09-21 · one way · Axel-exclusive $194.75

• Delta Air Lines DL3848 / DL2822: MKE 2027-09-21 13:12:00 → STL 2027-09-21 17:20:00; 1 stop(s) via DTW; 248 minutes. Local airport times.
  • DL3848: MKE 2027-09-21 13:12:00 → DTW 2027-09-21 15:24:00; layover at DTW: 69 minutes.
  • DL2822: DTW 2027-09-21 16:33:00 → STL 2027-09-21 17:20:00.

2027-09-21 · one way · Axel-exclusive $147.25

• Southwest Airlines WN3113: MKE 2027-09-21 15:40:00 → STL 2027-09-21 17:00:00; nonstop; 80 minutes. Local airport times.

2027-09-21 · one way · Axel-exclusive $161.50

• Southwest Airlines WN4802 / WN1089: MKE 2027-09-21 06:20:00 → STL 2027-09-21 11:00:00; 1 stop(s) via MDW; 280 minutes. Local airport times.
  • WN4802: MKE 2027-09-21 06:20:00 → MDW 2027-09-21 07:20:00; layover at MDW: 140 minutes.
  • WN1089: MDW 2027-09-21 09:40:00 → STL 2027-09-21 11:00:00.

2027-09-21 · one way · Axel-exclusive $161.50

• Southwest Airlines WN1086 / WN2714: MKE 2027-09-21 09:45:00 → STL 2027-09-21 15:25:00; 1 stop(s) via MCI; 340 minutes. Local airport times.
  • WN1086: MKE 2027-09-21 09:45:00 → MCI 2027-09-21 11:20:00; layover at MCI: 180 minutes.
  • WN2714: MCI 2027-09-21 14:20:00 → STL 2027-09-21 15:25:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Sep 20, 2027 · Return options
• Sep 22, 2027 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Milwaukee (MKE) to Saint Louis (STL) · Sep 21, 2027 · one way: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date.
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