Milwaukee (MKE) to Saint Louis (STL), Sep 13–22, 2027: from $285 round trip

Milwaukee (MKE) to Saint Louis (STL), Sep 13–22, 2027: from $285 round trip on Axel, checked Nov 13, 2026. Lowest published fare: $285 round trip, Axel-exclusive, Southwest Airlines, nonstop, Sep 13–22, 2027, 1 adult, economy, checked Nov 13, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in St. Louis for these nights (Sep 13–22, 2027 · 9 nights · 2 adults, 1 room): 3★ Residence Inn by Marriott St Louis Downtown · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton · 5★ The Ritz-Carlton, St. Louis

All hotels in St. Louis

Route overview: Milwaukee to Saint Louis (STL) flight deals

2027-09-13 → 2027-09-22 · Axel-exclusive $285

• Southwest Airlines WN3112: MKE 2027-09-13 08:00:00 → STL 2027-09-13 09:30:00; nonstop; 90 minutes. Local airport times.
• Southwest Airlines WN4097: STL 2027-09-22 08:00:00 → MKE 2027-09-22 09:15:00; nonstop; 75 minutes. Local airport times.

2027-09-13 → 2027-09-22 · Axel-exclusive $342

• United Airlines UA5412 / UA1857: MKE 2027-09-13 07:45:00 → STL 2027-09-13 12:22:00; 1 stop(s) via ORD; 277 minutes. Local airport times.
  • UA5412: MKE 2027-09-13 07:45:00 → ORD 2027-09-13 09:05:00; layover at ORD: 107 minutes.
  • UA1857: ORD 2027-09-13 10:52:00 → STL 2027-09-13 12:22:00.
• United Airlines UA4439 / UA5234: STL 2027-09-22 05:25:00 → MKE 2027-09-22 11:28:00; 1 stop(s) via ORD; 363 minutes. Local airport times.
  • UA4439: STL 2027-09-22 05:25:00 → ORD 2027-09-22 06:58:00; layover at ORD: 207 minutes.
  • UA5234: ORD 2027-09-22 10:25:00 → MKE 2027-09-22 11:28:00.

2027-09-13 → 2027-09-22 · Axel-exclusive $352

• American Airlines AA4920 / AA4372: MKE 2027-09-13 14:51:00 → STL 2027-09-13 19:52:00; 1 stop(s) via ORD; 301 minutes. Local airport times.
  • AA4920: MKE 2027-09-13 14:51:00 → ORD 2027-09-13 16:12:00; layover at ORD: 127 minutes.
  • AA4372: ORD 2027-09-13 18:19:00 → STL 2027-09-13 19:52:00.
• American Airlines AA3198 / AA6282: STL 2027-09-22 11:37:00 → MKE 2027-09-22 16:24:00; 1 stop(s) via ORD; 287 minutes. Local airport times.
  • AA3198: STL 2027-09-22 11:37:00 → ORD 2027-09-22 12:59:00; layover at ORD: 138 minutes.
  • AA6282: ORD 2027-09-22 15:17:00 → MKE 2027-09-22 16:24:00.

2027-09-13 → 2027-09-22 · Axel-exclusive $371

• Delta Air Lines DL3848 / DL2822: MKE 2027-09-13 13:12:00 → STL 2027-09-13 17:20:00; 1 stop(s) via DTW; 248 minutes. Local airport times.
  • DL3848: MKE 2027-09-13 13:12:00 → DTW 2027-09-13 15:24:00; layover at DTW: 69 minutes.
  • DL2822: DTW 2027-09-13 16:33:00 → STL 2027-09-13 17:20:00.
• Delta Air Lines DL1371 / DL3724: STL 2027-09-22 14:17:00 → MKE 2027-09-22 20:05:00; 1 stop(s) via DTW; 348 minutes. Local airport times.
  • DL1371: STL 2027-09-22 14:17:00 → DTW 2027-09-22 16:53:00; layover at DTW: 174 minutes.
  • DL3724: DTW 2027-09-22 19:47:00 → MKE 2027-09-22 20:05:00.

2027-09-13 → 2027-09-22 · Axel-exclusive $285

• Southwest Airlines WN3113: MKE 2027-09-13 15:40:00 → STL 2027-09-13 17:00:00; nonstop; 80 minutes. Local airport times.
• Southwest Airlines WN4097: STL 2027-09-22 08:00:00 → MKE 2027-09-22 09:15:00; nonstop; 75 minutes. Local airport times.

2027-09-13 → 2027-09-22 · Axel-exclusive $299

• Southwest Airlines WN1086 / WN2714: MKE 2027-09-13 09:45:00 → STL 2027-09-13 15:25:00; 1 stop(s) via MCI; 340 minutes. Local airport times.
  • WN1086: MKE 2027-09-13 09:45:00 → MCI 2027-09-13 11:20:00; layover at MCI: 180 minutes.
  • WN2714: MCI 2027-09-13 14:20:00 → STL 2027-09-13 15:25:00.
• Southwest Airlines WN4097: STL 2027-09-22 08:00:00 → MKE 2027-09-22 09:15:00; nonstop; 75 minutes. Local airport times.

2027-09-13 → 2027-09-22 · Axel-exclusive $299

• Southwest Airlines WN4802 / WN1089: MKE 2027-09-13 06:20:00 → STL 2027-09-13 11:00:00; 1 stop(s) via MDW; 280 minutes. Local airport times.
  • WN4802: MKE 2027-09-13 06:20:00 → MDW 2027-09-13 07:20:00; layover at MDW: 140 minutes.
  • WN1089: MDW 2027-09-13 09:40:00 → STL 2027-09-13 11:00:00.
• Southwest Airlines WN4097: STL 2027-09-22 08:00:00 → MKE 2027-09-22 09:15:00; nonstop; 75 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Sep 12, 2027 · Return options
• Sep 14, 2027 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Milwaukee (MKE) to Saint Louis (STL) · Sep 13, 2027 · return Sep 22, 2027: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Milwaukee to Saint Louis (STL) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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