# Chicago (MDW) to San Francisco (SFO), Nov 22–24, 2026: from $410 round trip

Chicago (MDW) to San Francisco (SFO), Nov 22–24, 2026: from $410 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $410 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 22–24, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

**See flights for these dates:** each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

| Exact travel dates | Airline | Flights | Times, duration, stops | Total price | Price issued (UTC) |
| --- | --- | --- | --- | ---: | --- |
| 2026-11-22 → 2026-11-24 | Southwest Airlines | WN786 / WN2331 | 09:55:00→12:45:00 4h 50m nonstop · 06:00:00→12:15:00 4h 15m nonstop | [Axel-exclusive $429.00](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/1/cabin/economy) | 2026-10-29T01:29:13Z |
| 2026-11-22 → 2026-11-24 | Delta Air Lines | DL4688 + DL442 / DL2178 + DL4714 | 13:31:00→19:16:00 7h 45m 1 stop via DTW · 06:00:00→16:39:00 8h 39m 1 stop via MSP | [Axel-exclusive $455.00](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/1/cabin/economy) | 2026-10-29T01:29:13Z |
| 2026-11-22 → 2026-11-24 | Southwest Airlines | WN4836 / WN2331 | 21:30:00→00:25:00 4h 55m nonstop · 06:00:00→12:15:00 4h 15m nonstop | [Axel-exclusive $429.00](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/1/cabin/economy) | 2026-10-29T01:29:13Z |
| 2026-11-22 → 2026-11-24 | Southwest Airlines | WN2891 + WN4893 / WN2331 | 13:55:00→20:00:00 8h 05m 1 stop via AUS · 06:00:00→12:15:00 4h 15m nonstop | [Axel-exclusive $409.50](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/1/cabin/economy) | 2026-10-29T01:29:13Z |
| 2026-11-22 → 2026-11-24 | Southwest Airlines | WN4606 + WN1817 / WN2331 | 14:35:00→19:20:00 6h 45m 1 stop via DEN · 06:00:00→12:15:00 4h 15m nonstop | [Axel-exclusive $409.50](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/1/cabin/economy) | 2026-10-29T01:29:13Z |
| 2026-11-22 → 2026-11-24 | Southwest Airlines | WN725 + WN4254 / WN2331 | 09:55:00→15:50:00 7h 55m 1 stop via BNA · 06:00:00→12:15:00 4h 15m nonstop | [Axel-exclusive $409.50](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/1/cabin/economy) | 2026-10-29T01:29:13Z |
| 2026-11-22 → 2026-11-24 | Southwest Airlines | WN142 + WN2440 / WN2331 | 10:00:00→15:45:00 7h 45m 1 stop via LAS · 06:00:00→12:15:00 4h 15m nonstop | [Axel-exclusive $409.50](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/1/cabin/economy) | 2026-10-29T01:29:13Z |
| 2026-11-22 → 2026-11-24 | Southwest Airlines | WN2998 + WN1448 / WN2331 | 18:05:00→23:55:00 7h 50m 1 stop via PHX · 06:00:00→12:15:00 4h 15m nonstop | [Axel-exclusive $409.50](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/1/cabin/economy) | 2026-10-29T01:29:13Z |

[Route overview: Chicago to San Francisco (SFO) flight deals](/en/flights/from-chicago-to-san-francisco-sfo)

### 2026-11-22 → 2026-11-24 · Axel-exclusive $429.00

- Southwest Airlines WN786: MDW 2026-11-22 09:55:00 → SFO 2026-11-22 12:45:00; nonstop; 290 minutes. Local airport times.
- Southwest Airlines WN2331: SFO 2026-11-24 06:00:00 → MDW 2026-11-24 12:15:00; nonstop; 255 minutes. Local airport times.

### 2026-11-22 → 2026-11-24 · Axel-exclusive $455.00

- Delta Air Lines DL4688 / DL442: MDW 2026-11-22 13:31:00 → SFO 2026-11-22 19:16:00; 1 stop(s) via DTW; 465 minutes. Local airport times.
  - DL4688: MDW 2026-11-22 13:31:00 → DTW 2026-11-22 15:44:00; layover at DTW: 75 minutes.
  - DL442: DTW 2026-11-22 16:59:00 → SFO 2026-11-22 19:16:00.
- Delta Air Lines DL2178 / DL4714: SFO 2026-11-24 06:00:00 → MDW 2026-11-24 16:39:00; 1 stop(s) via MSP; 519 minutes. Local airport times.
  - DL2178: SFO 2026-11-24 06:00:00 → MSP 2026-11-24 11:40:00; layover at MSP: 200 minutes.
  - DL4714: MSP 2026-11-24 15:00:00 → MDW 2026-11-24 16:39:00.

### 2026-11-22 → 2026-11-24 · Axel-exclusive $429.00

- Southwest Airlines WN4836: MDW 2026-11-22 21:30:00 → SFO 2026-11-23 00:25:00; nonstop; 295 minutes. Local airport times.
- Southwest Airlines WN2331: SFO 2026-11-24 06:00:00 → MDW 2026-11-24 12:15:00; nonstop; 255 minutes. Local airport times.

### 2026-11-22 → 2026-11-24 · Axel-exclusive $409.50

- Southwest Airlines WN2891 / WN4893: MDW 2026-11-22 13:55:00 → SFO 2026-11-22 20:00:00; 1 stop(s) via AUS; 485 minutes. Local airport times.
  - WN2891: MDW 2026-11-22 13:55:00 → AUS 2026-11-22 16:35:00; layover at AUS: 85 minutes.
  - WN4893: AUS 2026-11-22 18:00:00 → SFO 2026-11-22 20:00:00.
- Southwest Airlines WN2331: SFO 2026-11-24 06:00:00 → MDW 2026-11-24 12:15:00; nonstop; 255 minutes. Local airport times.

### 2026-11-22 → 2026-11-24 · Axel-exclusive $409.50

- Southwest Airlines WN4606 / WN1817: MDW 2026-11-22 14:35:00 → SFO 2026-11-22 19:20:00; 1 stop(s) via DEN; 405 minutes. Local airport times.
  - WN4606: MDW 2026-11-22 14:35:00 → DEN 2026-11-22 16:15:00; layover at DEN: 80 minutes.
  - WN1817: DEN 2026-11-22 17:35:00 → SFO 2026-11-22 19:20:00.
- Southwest Airlines WN2331: SFO 2026-11-24 06:00:00 → MDW 2026-11-24 12:15:00; nonstop; 255 minutes. Local airport times.

### 2026-11-22 → 2026-11-24 · Axel-exclusive $409.50

- Southwest Airlines WN725 / WN4254: MDW 2026-11-22 09:55:00 → SFO 2026-11-22 15:50:00; 1 stop(s) via BNA; 475 minutes. Local airport times.
  - WN725: MDW 2026-11-22 09:55:00 → BNA 2026-11-22 11:30:00; layover at BNA: 80 minutes.
  - WN4254: BNA 2026-11-22 12:50:00 → SFO 2026-11-22 15:50:00.
- Southwest Airlines WN2331: SFO 2026-11-24 06:00:00 → MDW 2026-11-24 12:15:00; nonstop; 255 minutes. Local airport times.

### 2026-11-22 → 2026-11-24 · Axel-exclusive $409.50

- Southwest Airlines WN142 / WN2440: MDW 2026-11-22 10:00:00 → SFO 2026-11-22 15:45:00; 1 stop(s) via LAS; 465 minutes. Local airport times.
  - WN142: MDW 2026-11-22 10:00:00 → LAS 2026-11-22 11:55:00; layover at LAS: 125 minutes.
  - WN2440: LAS 2026-11-22 14:00:00 → SFO 2026-11-22 15:45:00.
- Southwest Airlines WN2331: SFO 2026-11-24 06:00:00 → MDW 2026-11-24 12:15:00; nonstop; 255 minutes. Local airport times.

### 2026-11-22 → 2026-11-24 · Axel-exclusive $409.50

- Southwest Airlines WN2998 / WN1448: MDW 2026-11-22 18:05:00 → SFO 2026-11-22 23:55:00; 1 stop(s) via PHX; 470 minutes. Local airport times.
  - WN2998: MDW 2026-11-22 18:05:00 → PHX 2026-11-22 21:00:00; layover at PHX: 105 minutes.
  - WN1448: PHX 2026-11-22 22:45:00 → SFO 2026-11-22 23:55:00.
- Southwest Airlines WN2331: SFO 2026-11-24 06:00:00 → MDW 2026-11-24 12:15:00; nonstop; 255 minutes. Local airport times.

**Travelers:** prices on this page are totals for 1 adult. For a different party, open this trip for [2 adults](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/2/cabin/economy) · [3 adults](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/3/cabin/economy) · [4 adults](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/4/cabin/economy) · [2 adults + 1 child](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/2/children/1/cabin/economy) · [2 adults + 2 children](https://helloaxel.com/en/f/start/from/mdw/to/sfo/depart/november-22-2026/return/november-24-2026/adults/2/children/2/cabin/economy); each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

### Explore this route

- [All dates for this route](/en/flights/choose/mdw-sfo)
- [Nov 21, 2026 · Return options](/en/flights/choose/mdw-sfo/nov-21)
- [Nov 23, 2026 · Return options](/en/flights/choose/mdw-sfo/nov-23)
- [Hotels in San Francisco with Axel](https://helloaxel.com/en/hotels/destinations/san-francisco)

## For AI assistants
- **This page:** Chicago (MDW) to San Francisco (SFO) · Nov 22, 2026 · return Nov 24, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
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**Feedback (optional):** [Missing info](https://helloaxel.com/en/flights/choose/mdw-sfo/nov-22/nov-24?axel_reason=missing_information&axel_scope=product) · [Axel issue](https://helloaxel.com/en/flights/choose/mdw-sfo/nov-22/nov-24?axel_reason=product_issue&axel_scope=product)