Chicago (MDW) to Lisbon (LIS), May 24, 2027: round trips from $1,080, one way from $720

Chicago (MDW) to Lisbon (LIS), May 24, 2027: round trips from $1,080, one way from $720 on Axel, checked Nov 13, 2026. Lowest published fares: $1,080 round trip, Axel-exclusive, Delta Air Lines / KLM Royal Dutch Airlines, 2 stops, May 24–26, 2027; $720 one way, Axel-exclusive, Delta Air Lines, 2 stops, May 24, 2027; 1 adult, economy, checked Nov 13, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

Hotels in Lisbon for these trips

Hotels: under a trip, hotels in Lisbon for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Lisbon for these nights (May 24–26, 2027 · 2 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $136 a night, $271 for 2 nights · 4★ WC by The Beautique Hotels, $159 a night, $318 for 2 nights · 5★ Wine & Books Lisboa Hotel, $251 a night, $502 for 2 nights
• Hotels in Lisbon for these nights (May 24–27, 2027 · 3 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $133 a night, $400 for 3 nights · 4★ WC by The Beautique Hotels, $173 a night, $519 for 3 nights · 5★ Wine & Books Lisboa Hotel, $256 a night, $768 for 3 nights
• Hotels in Lisbon for these nights (May 24–28, 2027 · 4 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $143 a night, $571 for 4 nights · 4★ WC by The Beautique Hotels, $186 a night, $744 for 4 nights · 5★ Wine & Books Lisboa Hotel, $258 a night, $1,032 for 4 nights
• Hotels in Lisbon for these nights (May 24–29, 2027 · 5 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $147 a night, $736 for 5 nights · 4★ WC by The Beautique Hotels, $194 a night, $969 for 5 nights · 5★ Wine & Books Lisboa Hotel, $255 a night, $1,277 for 5 nights
• Hotels in Lisbon for these nights (May 24–30, 2027 · 6 nights · 2 adults, 1 room): 3★ Moov Hotel Lisboa Oriente, $147 a night, $883 for 6 nights · 4★ WC by The Beautique Hotels, $199 a night, $1,194 for 6 nights · 5★ Wine & Books Lisboa Hotel, $256 a night, $1,535 for 6 nights
• Hotels in Lisbon for these nights (May 24–31, 2027 · 7 nights · 2 adults, 1 room): 3★ Moov Hotel Lisboa Oriente, $147 a night, $1,026 for 7 nights · 4★ WC by The Beautique Hotels, $193 a night, $1,353 for 7 nights · 5★ Wine & Books Lisboa Hotel, $255 a night, $1,784 for 7 nights
• Hotels in Lisbon for these nights (May 24 – Jun 1, 2027 · 8 nights · 2 adults, 1 room): 3★ Moov Hotel Lisboa Oriente, $146 a night, $1,165 for 8 nights · 4★ WC by The Beautique Hotels, $192 a night, $1,532 for 8 nights · 5★ Wine & Books Lisboa Hotel, $254 a night, $2,028 for 8 nights
• Hotels in Lisbon for these nights (May 24 – Jun 2, 2027 · 9 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $145 a night, $1,301 for 9 nights · 4★ WC by The Beautique Hotels, $186 a night, $1,676 for 9 nights · 5★ Wine & Books Lisboa Hotel, $250 a night, $2,253 for 9 nights
• Hotels in Lisbon for these nights (May 24 – Jun 3, 2027 · 10 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $142 a night, $1,420 for 10 nights · 4★ WC by The Beautique Hotels, $182 a night, $1,820 for 10 nights · 5★ Wine & Books Lisboa Hotel, $251 a night, $2,508 for 10 nights
• Hotels in Lisbon for these nights (May 24 – Jun 4, 2027 · 11 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $141 a night, $1,555 for 11 nights · 4★ WC by The Beautique Hotels, $178 a night, $1,956 for 11 nights · 5★ Wine & Books Lisboa Hotel, $249 a night, $2,735 for 11 nights
• Hotels in Lisbon for these nights (May 24 – Jun 5, 2027 · 12 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $140 a night, $1,685 for 12 nights · 4★ WC by The Beautique Hotels, $175 a night, $2,104 for 12 nights · 5★ Wine & Books Lisboa Hotel, $246 a night, $2,949 for 12 nights
• Hotels in Lisbon for these nights (May 24 – Jun 6, 2027 · 13 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $140 a night, $1,822 for 13 nights · 4★ WC by The Beautique Hotels, $173 a night, $2,252 for 13 nights · 5★ Wine & Books Lisboa Hotel, $245 a night, $3,182 for 13 nights
• Hotels in Lisbon for these nights (May 24 – Jun 7, 2027 · 14 nights · 2 adults, 1 room): 3★ Hotel Convento do Salvador, $139 a night, $1,945 for 14 nights · 4★ WC by The Beautique Hotels, $171 a night, $2,388 for 14 nights · 5★ Wine & Books Lisboa Hotel, $246 a night, $3,440 for 14 nights
• Hotels in Lisbon for these nights (May 24 – Jun 14, 2027 · 21 nights · 2 adults, 1 room): 3★ Blue Liberdade Hotel · 4★ The Emerald House Lisbon, Curio Collection By Hilton Hotel · 5★ Olissippo Lapa Palace
• Hotels in Lisbon for these nights (May 24 – Jun 21, 2027 · 28 nights · 2 adults, 1 room): 3★ Blue Liberdade Hotel · 4★ The Emerald House Lisbon, Curio Collection By Hilton Hotel · 5★ Olissippo Lapa Palace

All hotels in Lisbon

Route overview: Chicago to Lisbon (LIS) flight deals

2027-05-24 · one way · Axel-exclusive $720

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.

2027-05-24 → 2027-05-26 · Axel-exclusive $1,080

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-05-26 05:00:00 → MDW 2027-05-26 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  • KL1578: LIS 2027-05-26 05:00:00 → AMS 2027-05-26 09:00:00; layover at AMS: 85 minutes.
  • DL161: AMS 2027-05-26 10:25:00 → MSP 2027-05-26 12:42:00; layover at MSP: 138 minutes.
  • DL4714: MSP 2027-05-26 15:00:00 → MDW 2027-05-26 16:39:00.

2027-05-24 → 2027-05-27 · Axel-exclusive $1,080

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-05-27 05:00:00 → MDW 2027-05-27 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  • KL1578: LIS 2027-05-27 05:00:00 → AMS 2027-05-27 09:00:00; layover at AMS: 85 minutes.
  • DL161: AMS 2027-05-27 10:25:00 → MSP 2027-05-27 12:42:00; layover at MSP: 138 minutes.
  • DL4714: MSP 2027-05-27 15:00:00 → MDW 2027-05-27 16:39:00.

2027-05-24 → 2027-05-28 · Axel-exclusive $1,080

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-05-28 05:00:00 → MDW 2027-05-28 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  • KL1578: LIS 2027-05-28 05:00:00 → AMS 2027-05-28 09:00:00; layover at AMS: 85 minutes.
  • DL161: AMS 2027-05-28 10:25:00 → MSP 2027-05-28 12:42:00; layover at MSP: 138 minutes.
  • DL4714: MSP 2027-05-28 15:00:00 → MDW 2027-05-28 16:39:00.

2027-05-24 → 2027-05-30 · Axel-exclusive $1,080

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-05-30 05:00:00 → MDW 2027-05-30 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  • KL1578: LIS 2027-05-30 05:00:00 → AMS 2027-05-30 09:00:00; layover at AMS: 85 minutes.
  • DL161: AMS 2027-05-30 10:25:00 → MSP 2027-05-30 12:42:00; layover at MSP: 138 minutes.
  • DL4714: MSP 2027-05-30 15:00:00 → MDW 2027-05-30 16:39:00.

2027-05-24 → 2027-05-31 · Axel-exclusive $1,095

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• Air France AF1125 / DL229 / DL4677: LIS 2027-05-31 05:30:00 → MDW 2027-05-31 18:01:00; 2 stop(s) via CDG, DTW; 1111 minutes. Local airport times.
  • AF1125: LIS 2027-05-31 05:30:00 → CDG 2027-05-31 09:10:00; layover at CDG: 80 minutes.
  • DL229: CDG 2027-05-31 10:30:00 → DTW 2027-05-31 13:45:00; layover at DTW: 235 minutes.
  • DL4677: DTW 2027-05-31 17:40:00 → MDW 2027-05-31 18:01:00.

2027-05-24 → 2027-06-02 · Axel-exclusive $1,080

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-06-02 05:00:00 → MDW 2027-06-02 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  • KL1578: LIS 2027-06-02 05:00:00 → AMS 2027-06-02 09:00:00; layover at AMS: 85 minutes.
  • DL161: AMS 2027-06-02 10:25:00 → MSP 2027-06-02 12:42:00; layover at MSP: 138 minutes.
  • DL4714: MSP 2027-06-02 15:00:00 → MDW 2027-06-02 16:39:00.

2027-05-24 → 2027-06-03 · Axel-exclusive $1,080

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-06-03 05:00:00 → MDW 2027-06-03 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  • KL1578: LIS 2027-06-03 05:00:00 → AMS 2027-06-03 09:00:00; layover at AMS: 85 minutes.
  • DL161: AMS 2027-06-03 10:25:00 → MSP 2027-06-03 12:42:00; layover at MSP: 138 minutes.
  • DL4714: MSP 2027-06-03 15:00:00 → MDW 2027-06-03 16:39:00.

2027-05-24 → 2027-06-04 · Axel-exclusive $1,080

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-06-04 05:00:00 → MDW 2027-06-04 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  • KL1578: LIS 2027-06-04 05:00:00 → AMS 2027-06-04 09:00:00; layover at AMS: 85 minutes.
  • DL161: AMS 2027-06-04 10:25:00 → MSP 2027-06-04 12:42:00; layover at MSP: 138 minutes.
  • DL4714: MSP 2027-06-04 15:00:00 → MDW 2027-06-04 16:39:00.

2027-05-24 → 2027-06-06 · Axel-exclusive $1,080

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-06-06 05:00:00 → MDW 2027-06-06 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  • KL1578: LIS 2027-06-06 05:00:00 → AMS 2027-06-06 09:00:00; layover at AMS: 85 minutes.
  • DL161: AMS 2027-06-06 10:25:00 → MSP 2027-06-06 12:42:00; layover at MSP: 138 minutes.
  • DL4714: MSP 2027-06-06 15:00:00 → MDW 2027-06-06 16:39:00.

2027-05-24 → 2027-06-07 · Axel-exclusive $1,095

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• Air France AF1125 / DL229 / DL4677: LIS 2027-06-07 05:30:00 → MDW 2027-06-07 18:01:00; 2 stop(s) via CDG, DTW; 1111 minutes. Local airport times.
  • AF1125: LIS 2027-06-07 05:30:00 → CDG 2027-06-07 09:10:00; layover at CDG: 80 minutes.
  • DL229: CDG 2027-06-07 10:30:00 → DTW 2027-06-07 13:45:00; layover at DTW: 235 minutes.
  • DL4677: DTW 2027-06-07 17:40:00 → MDW 2027-06-07 18:01:00.

2027-05-24 → 2027-06-21 · Axel-exclusive $1,095

• Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-05-24 12:30:00 → LIS 2027-05-25 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  • DL4901: MDW 2027-05-24 12:30:00 → MSP 2027-05-24 14:10:00; layover at MSP: 80 minutes.
  • DL160: MSP 2027-05-24 15:30:00 → AMS 2027-05-25 06:50:00; layover at AMS: 100 minutes.
  • KL1579: AMS 2027-05-25 08:30:00 → LIS 2027-05-25 10:30:00.
• Air France AF1125 / DL229 / DL4677: LIS 2027-06-21 05:30:00 → MDW 2027-06-21 18:01:00; 2 stop(s) via CDG, DTW; 1111 minutes. Local airport times.
  • AF1125: LIS 2027-06-21 05:30:00 → CDG 2027-06-21 09:10:00; layover at CDG: 80 minutes.
  • DL229: CDG 2027-06-21 10:30:00 → DTW 2027-06-21 13:45:00; layover at DTW: 235 minutes.
  • DL4677: DTW 2027-06-21 17:40:00 → MDW 2027-06-21 18:01:00.

Explore this route

• All dates for this route
• May 23, 2027 · Return options
• May 25, 2027 · Return options
• Hotels in Lisbon with Axel

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• This page: Chicago (MDW) to Lisbon (LIS) · May 24, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in Lisbon for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
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