# Chicago (MDW) to Lisbon (LIS), Feb 22, 2027: round trips from $785, one way from $530

Chicago (MDW) to Lisbon (LIS), Feb 22, 2027: round trips from $785, one way from $530 on Axel, checked Nov 13, 2026. Lowest published fares: $785 round trip, Axel-exclusive, Delta Air Lines / KLM Royal Dutch Airlines, 2 stops, Feb 22–24, 2027; $530 one way, Axel-exclusive, Delta Air Lines, 2 stops, Feb 22, 2027; 1 adult, economy, checked Nov 13, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

**Prices by return date:** match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

**Date links** open published trip details for exploration. **Price links** open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

| Exact travel dates | Airline | Flights | Times, duration, stops | Total price | Price checked |
| --- | --- | --- | --- | ---: | --- |
| [2027-02-22 · one way](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/one-way) | Delta Air Lines | DL4901 + DL160 + KL1579 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS | [Axel-exclusive $530](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/trip/one-way/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS) | Nov 13, 2026 |
| [2027-02-22 → 2027-02-24](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/feb-24) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/february-24-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-02-24.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-02-25](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/feb-25) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/february-25-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-02-25.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-02-26](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/feb-26) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/february-26-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-02-26.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-02-27](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/feb-27) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/february-27-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-02-27.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-02-28](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/feb-28) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/february-28-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-02-28.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-01](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-1) | Delta Air Lines / Air France | DL4901 + DL160 + KL1579 / AF1125 + DL229 + DL4677 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:30:00→18:01:00 18h 31m 2 stops via CDG, DTW | [Axel-exclusive $795](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-1-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-01.AF.2.AF1125-DL229-DL4677.CDG-DTW) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-02](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-2) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-2-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-02.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-03](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-3) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-3-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-03.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-04](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-4) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-4-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-04.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-05](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-5) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-5-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-05.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-06](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-6) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-6-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-06.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-07](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-7) | Delta Air Lines / KLM Royal Dutch Airlines | DL4901 + DL160 + KL1579 / KL1578 + DL161 + DL4714 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:00:00→16:39:00 17h 39m 2 stops via AMS, MSP | [Axel-exclusive $785](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-7-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-07.KL.2.KL1578-DL161-DL4714.AMS-MSP) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-08](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-8) | Delta Air Lines / Air France | DL4901 + DL160 + KL1579 / AF1125 + DL229 + DL4677 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:30:00→18:01:00 18h 31m 2 stops via CDG, DTW | [Axel-exclusive $795](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-8-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-08.AF.2.AF1125-DL229-DL4677.CDG-DTW) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-15](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-15) | Delta Air Lines / Air France | DL4901 + DL160 + KL1579 / AF1125 + DL229 + DL4677 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:30:00→19:01:00 18h 31m 2 stops via CDG, DTW | [Axel-exclusive $795](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-15-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-15.AF.2.AF1125-DL229-DL4677.CDG-DTW) | Nov 13, 2026 |
| [2027-02-22 → 2027-03-22](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22/mar-22) | Delta Air Lines / Air France | DL4901 + DL160 + KL1579 / AF1125 + DL229 + DL4677 | 12:30:00→10:30:00 16h 00m 2 stops via MSP, AMS · 05:30:00→19:01:00 18h 31m 2 stops via CDG, DTW | [Axel-exclusive $854](https://helloaxel.com/en/f/start/from/mdw/to/lis/depart/february-22-2027/return/march-22-2027/adults/1/cabin/economy?example_flight=MDW-LIS.2027-02-22.DL.2.DL4901-DL160-KL1579.MSP-AMS%7ELIS-MDW.2027-03-22.AF.2.AF1125-DL229-DL4677.CDG-DTW) | Nov 13, 2026 |

### Hotels in Lisbon for these trips

**Hotels:** under a trip, hotels in Lisbon for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

- Hotels in Lisbon for these nights (Feb 22–24, 2027 · 2 nights · 2 adults, 1 room): 3★ [Hotel Ikonik Lisboa, $73 a night, $146 for 2 nights](https://helloaxel.com/en/hotels/lisbon/hotel-ikonik-lisboa-1251086/2027-02-22/2027-02-24/2-adults) · 4★ [WC by The Beautique Hotels, $90 a night, $180 for 2 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-02-24/2-adults) · 5★ [Palácio do Governador - Lisbon Hotel & Spa, $176 a night, $352 for 2 nights](https://helloaxel.com/en/hotels/lisbon/palacio-do-governador-lisbon-hotel-spa-1034993/2027-02-22/2027-02-24/2-adults)
- Hotels in Lisbon for these nights (Feb 22–25, 2027 · 3 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $75 a night, $224 for 3 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-02-25/2-adults) · 4★ [WC by The Beautique Hotels, $90 a night, $270 for 3 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-02-25/2-adults) · 5★ [Palácio do Governador - Lisbon Hotel & Spa, $174 a night, $521 for 3 nights](https://helloaxel.com/en/hotels/lisbon/palacio-do-governador-lisbon-hotel-spa-1034993/2027-02-22/2027-02-25/2-adults)
- Hotels in Lisbon for these nights (Feb 22–26, 2027 · 4 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $74 a night, $296 for 4 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-02-26/2-adults) · 4★ [WC by The Beautique Hotels, $90 a night, $360 for 4 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-02-26/2-adults) · 5★ [Palácio do Governador - Lisbon Hotel & Spa, $174 a night, $697 for 4 nights](https://helloaxel.com/en/hotels/lisbon/palacio-do-governador-lisbon-hotel-spa-1034993/2027-02-22/2027-02-26/2-adults)
- Hotels in Lisbon for these nights (Feb 22–27, 2027 · 5 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $74 a night, $372 for 5 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-02-27/2-adults) · 4★ [WC by The Beautique Hotels, $89 a night, $444 for 5 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-02-27/2-adults) · 5★ [Palácio do Governador - Lisbon Hotel & Spa, $175 a night, $873 for 5 nights](https://helloaxel.com/en/hotels/lisbon/palacio-do-governador-lisbon-hotel-spa-1034993/2027-02-22/2027-02-27/2-adults)
- Hotels in Lisbon for these nights (Feb 22–28, 2027 · 6 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $75 a night, $448 for 6 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-02-28/2-adults) · 4★ [WC by The Beautique Hotels, $88 a night, $528 for 6 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-02-28/2-adults) · 5★ [Palácio do Governador - Lisbon Hotel & Spa, $177 a night, $1,059 for 6 nights](https://helloaxel.com/en/hotels/lisbon/palacio-do-governador-lisbon-hotel-spa-1034993/2027-02-22/2027-02-28/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 1, 2027 · 7 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $74 a night, $516 for 7 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-03-01/2-adults) · 4★ [WC by The Beautique Hotels, $88 a night, $618 for 7 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-03-01/2-adults) · 5★ [Palácio do Governador - Lisbon Hotel & Spa, $177 a night, $1,242 for 7 nights](https://helloaxel.com/en/hotels/lisbon/palacio-do-governador-lisbon-hotel-spa-1034993/2027-02-22/2027-03-01/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 2, 2027 · 8 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $75 a night, $601 for 8 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-03-02/2-adults) · 4★ [WC by The Beautique Hotels, $90 a night, $720 for 8 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-03-02/2-adults) · 5★ [Palácio do Governador - Lisbon Hotel & Spa, $180 a night, $1,439 for 8 nights](https://helloaxel.com/en/hotels/lisbon/palacio-do-governador-lisbon-hotel-spa-1034993/2027-02-22/2027-03-02/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 3, 2027 · 9 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $76 a night, $686 for 9 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-03-03/2-adults) · 4★ [WC by The Beautique Hotels, $91 a night, $822 for 9 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-03-03/2-adults) · 5★ [Wine & Books Lisboa Hotel, $182 a night, $1,636 for 9 nights](https://helloaxel.com/en/hotels/lisbon/wine-books-lisboa-hotel-1470240/2027-02-22/2027-03-03/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 4, 2027 · 10 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $77 a night, $771 for 10 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-03-04/2-adults) · 4★ [WC by The Beautique Hotels, $92 a night, $924 for 10 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-03-04/2-adults) · 5★ [Wine & Books Lisboa Hotel, $182 a night, $1,818 for 10 nights](https://helloaxel.com/en/hotels/lisbon/wine-books-lisboa-hotel-1470240/2027-02-22/2027-03-04/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 5, 2027 · 11 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $78 a night, $856 for 11 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-03-05/2-adults) · 4★ [WC by The Beautique Hotels, $92 a night, $1,011 for 11 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-03-05/2-adults) · 5★ [Wine & Books Lisboa Hotel, $194 a night, $2,134 for 11 nights](https://helloaxel.com/en/hotels/lisbon/wine-books-lisboa-hotel-1470240/2027-02-22/2027-03-05/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 6, 2027 · 12 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $82 a night, $981 for 12 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-03-06/2-adults) · 4★ [WC by The Beautique Hotels, $93 a night, $1,113 for 12 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-03-06/2-adults) · 5★ [Wine & Books Lisboa Hotel, $204 a night, $2,444 for 12 nights](https://helloaxel.com/en/hotels/lisbon/wine-books-lisboa-hotel-1470240/2027-02-22/2027-03-06/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 7, 2027 · 13 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $84 a night, $1,094 for 13 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-03-07/2-adults) · 4★ [WC by The Beautique Hotels, $93 a night, $1,215 for 13 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-03-07/2-adults) · 5★ [Wine & Books Lisboa Hotel, $212 a night, $2,760 for 13 nights](https://helloaxel.com/en/hotels/lisbon/wine-books-lisboa-hotel-1470240/2027-02-22/2027-03-07/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 8, 2027 · 14 nights · 2 adults, 1 room): 3★ [Dorma Saldanha Hotel, $84 a night, $1,170 for 14 nights](https://helloaxel.com/en/hotels/lisbon/dorma-saldanha-hotel-1178978/2027-02-22/2027-03-08/2-adults) · 4★ [WC by The Beautique Hotels, $94 a night, $1,317 for 14 nights](https://helloaxel.com/en/hotels/lisbon/wc-by-the-beautique-hotels-1469226/2027-02-22/2027-03-08/2-adults) · 5★ [Wine & Books Lisboa Hotel, $220 a night, $3,082 for 14 nights](https://helloaxel.com/en/hotels/lisbon/wine-books-lisboa-hotel-1470240/2027-02-22/2027-03-08/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 15, 2027 · 21 nights · 2 adults, 1 room): 3★ [Blue Liberdade Hotel](https://helloaxel.com/en/hotels/lisbon/blue-liberdade-hotel-1242315/2027-02-22/2027-03-15/2-adults) · 4★ [The Emerald House Lisbon, Curio Collection By Hilton Hotel](https://helloaxel.com/en/hotels/lisbon/the-emerald-house-lisbon-curio-collection-by-hilton-hotel-1457099/2027-02-22/2027-03-15/2-adults) · 5★ [Olissippo Lapa Palace](https://helloaxel.com/en/hotels/lisbon/olissippo-lapa-palace-1041921/2027-02-22/2027-03-15/2-adults)
- Hotels in Lisbon for these nights (Feb 22 – Mar 22, 2027 · 28 nights · 2 adults, 1 room): 3★ [Blue Liberdade Hotel](https://helloaxel.com/en/hotels/lisbon/blue-liberdade-hotel-1242315/2027-02-22/2027-03-22/2-adults) · 4★ [The Emerald House Lisbon, Curio Collection By Hilton Hotel](https://helloaxel.com/en/hotels/lisbon/the-emerald-house-lisbon-curio-collection-by-hilton-hotel-1457099/2027-02-22/2027-03-22/2-adults) · 5★ [Olissippo Lapa Palace](https://helloaxel.com/en/hotels/lisbon/olissippo-lapa-palace-1041921/2027-02-22/2027-03-22/2-adults)

[All hotels in Lisbon](https://helloaxel.com/en/hotels/destinations/lisbon)

[Route overview: Chicago to Lisbon (LIS) flight deals](/en/flights/from-chicago-to-lisbon-lis)

### 2027-02-22 · one way · Axel-exclusive $530

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.

### 2027-02-22 → 2027-02-24 · Axel-exclusive $785

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-02-24 05:00:00 → MDW 2027-02-24 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  - KL1578: LIS 2027-02-24 05:00:00 → AMS 2027-02-24 09:00:00; layover at AMS: 85 minutes.
  - DL161: AMS 2027-02-24 10:25:00 → MSP 2027-02-24 12:42:00; layover at MSP: 138 minutes.
  - DL4714: MSP 2027-02-24 15:00:00 → MDW 2027-02-24 16:39:00.

### 2027-02-22 → 2027-02-25 · Axel-exclusive $785

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-02-25 05:00:00 → MDW 2027-02-25 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  - KL1578: LIS 2027-02-25 05:00:00 → AMS 2027-02-25 09:00:00; layover at AMS: 85 minutes.
  - DL161: AMS 2027-02-25 10:25:00 → MSP 2027-02-25 12:42:00; layover at MSP: 138 minutes.
  - DL4714: MSP 2027-02-25 15:00:00 → MDW 2027-02-25 16:39:00.

### 2027-02-22 → 2027-02-26 · Axel-exclusive $785

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-02-26 05:00:00 → MDW 2027-02-26 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  - KL1578: LIS 2027-02-26 05:00:00 → AMS 2027-02-26 09:00:00; layover at AMS: 85 minutes.
  - DL161: AMS 2027-02-26 10:25:00 → MSP 2027-02-26 12:42:00; layover at MSP: 138 minutes.
  - DL4714: MSP 2027-02-26 15:00:00 → MDW 2027-02-26 16:39:00.

### 2027-02-22 → 2027-02-28 · Axel-exclusive $785

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-02-28 05:00:00 → MDW 2027-02-28 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  - KL1578: LIS 2027-02-28 05:00:00 → AMS 2027-02-28 09:00:00; layover at AMS: 85 minutes.
  - DL161: AMS 2027-02-28 10:25:00 → MSP 2027-02-28 12:42:00; layover at MSP: 138 minutes.
  - DL4714: MSP 2027-02-28 15:00:00 → MDW 2027-02-28 16:39:00.

### 2027-02-22 → 2027-03-01 · Axel-exclusive $795

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- Air France AF1125 / DL229 / DL4677: LIS 2027-03-01 05:30:00 → MDW 2027-03-01 18:01:00; 2 stop(s) via CDG, DTW; 1111 minutes. Local airport times.
  - AF1125: LIS 2027-03-01 05:30:00 → CDG 2027-03-01 09:10:00; layover at CDG: 80 minutes.
  - DL229: CDG 2027-03-01 10:30:00 → DTW 2027-03-01 13:45:00; layover at DTW: 235 minutes.
  - DL4677: DTW 2027-03-01 17:40:00 → MDW 2027-03-01 18:01:00.

### 2027-02-22 → 2027-03-03 · Axel-exclusive $785

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-03-03 05:00:00 → MDW 2027-03-03 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  - KL1578: LIS 2027-03-03 05:00:00 → AMS 2027-03-03 09:00:00; layover at AMS: 85 minutes.
  - DL161: AMS 2027-03-03 10:25:00 → MSP 2027-03-03 12:42:00; layover at MSP: 138 minutes.
  - DL4714: MSP 2027-03-03 15:00:00 → MDW 2027-03-03 16:39:00.

### 2027-02-22 → 2027-03-04 · Axel-exclusive $785

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-03-04 05:00:00 → MDW 2027-03-04 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  - KL1578: LIS 2027-03-04 05:00:00 → AMS 2027-03-04 09:00:00; layover at AMS: 85 minutes.
  - DL161: AMS 2027-03-04 10:25:00 → MSP 2027-03-04 12:42:00; layover at MSP: 138 minutes.
  - DL4714: MSP 2027-03-04 15:00:00 → MDW 2027-03-04 16:39:00.

### 2027-02-22 → 2027-03-05 · Axel-exclusive $785

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-03-05 05:00:00 → MDW 2027-03-05 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  - KL1578: LIS 2027-03-05 05:00:00 → AMS 2027-03-05 09:00:00; layover at AMS: 85 minutes.
  - DL161: AMS 2027-03-05 10:25:00 → MSP 2027-03-05 12:42:00; layover at MSP: 138 minutes.
  - DL4714: MSP 2027-03-05 15:00:00 → MDW 2027-03-05 16:39:00.

### 2027-02-22 → 2027-03-07 · Axel-exclusive $785

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- KLM Royal Dutch Airlines KL1578 / DL161 / DL4714: LIS 2027-03-07 05:00:00 → MDW 2027-03-07 16:39:00; 2 stop(s) via AMS, MSP; 1059 minutes. Local airport times.
  - KL1578: LIS 2027-03-07 05:00:00 → AMS 2027-03-07 09:00:00; layover at AMS: 85 minutes.
  - DL161: AMS 2027-03-07 10:25:00 → MSP 2027-03-07 12:42:00; layover at MSP: 138 minutes.
  - DL4714: MSP 2027-03-07 15:00:00 → MDW 2027-03-07 16:39:00.

### 2027-02-22 → 2027-03-08 · Axel-exclusive $795

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- Air France AF1125 / DL229 / DL4677: LIS 2027-03-08 05:30:00 → MDW 2027-03-08 18:01:00; 2 stop(s) via CDG, DTW; 1111 minutes. Local airport times.
  - AF1125: LIS 2027-03-08 05:30:00 → CDG 2027-03-08 09:10:00; layover at CDG: 80 minutes.
  - DL229: CDG 2027-03-08 10:30:00 → DTW 2027-03-08 13:45:00; layover at DTW: 235 minutes.
  - DL4677: DTW 2027-03-08 17:40:00 → MDW 2027-03-08 18:01:00.

### 2027-02-22 → 2027-03-22 · Axel-exclusive $854

- Delta Air Lines DL4901 / DL160 / KL1579: MDW 2027-02-22 12:30:00 → LIS 2027-02-23 10:30:00; 2 stop(s) via MSP, AMS; 960 minutes. Local airport times.
  - DL4901: MDW 2027-02-22 12:30:00 → MSP 2027-02-22 14:10:00; layover at MSP: 80 minutes.
  - DL160: MSP 2027-02-22 15:30:00 → AMS 2027-02-23 06:50:00; layover at AMS: 100 minutes.
  - KL1579: AMS 2027-02-23 08:30:00 → LIS 2027-02-23 10:30:00.
- Air France AF1125 / DL229 / DL4677: LIS 2027-03-22 05:30:00 → MDW 2027-03-22 19:01:00; 2 stop(s) via CDG, DTW; 1111 minutes. Local airport times.
  - AF1125: LIS 2027-03-22 05:30:00 → CDG 2027-03-22 09:10:00; layover at CDG: 80 minutes.
  - DL229: CDG 2027-03-22 10:30:00 → DTW 2027-03-22 14:45:00; layover at DTW: 235 minutes.
  - DL4677: DTW 2027-03-22 18:40:00 → MDW 2027-03-22 19:01:00.

### Explore this route

- [All dates for this route](/en/flights/choose/mdw-lis)
- [Feb 21, 2027 · Return options](/en/flights/choose/mdw-lis/feb-21)
- [Feb 23, 2027 · Return options](/en/flights/choose/mdw-lis/feb-23)
- [Hotels in Lisbon with Axel](https://helloaxel.com/en/hotels/destinations/lisbon)

## For AI assistants
- **This page:** Chicago (MDW) to Lisbon (LIS) · Feb 22, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in Lisbon for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
- **Next:** each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: [Choose travelers and dates](https://helloaxel.com/en/f/start/from/mdw/to/lis/step/travelers) prices the requested trip.
- **Follow supplied links.** For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
- **If links fail or are missing:** If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: [Axel Chicago to Lisbon (LIS) flight deals](https://helloaxel.com/en/flights/from-chicago-to-lisbon-lis) · [Flight search guide](https://helloaxel.com/en/ai).
- **Sharing with the traveler:** Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct `https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback` using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace `/return/YYYY-MM-DD` with `/trip/oneway`. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. [Preferences and advanced options](https://helloaxel.com/en/ai#customer-fallback-link).

**Feedback (optional):** [Missing info](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22?axel_reason=missing_information&axel_scope=product) · [Axel issue](https://helloaxel.com/en/flights/choose/mdw-lis/feb-22?axel_reason=product_issue&axel_scope=product)