Chicago (MDW) to Houston (HOU), Nov 16–21, 2026: from $280 round trip

Chicago (MDW) to Houston (HOU), Nov 16–21, 2026: from $280 round trip on Axel, checked Oct 29, 2026. Lowest published fare: $280 round trip, Axel-exclusive, Southwest Airlines, 1 stop, Nov 16–21, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in Giza for these trips

Hotels: under a trip, hotels in Giza for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Giza for these nights (Nov 16–21, 2026 · 5 nights · 2 adults, 1 room): 3★ Mamlouk Pyramids Hotel · 4★ Stay Inn Hotel Cairo Hotel · 5★ Four Seasons Hotel Cairo at Nile Plaza

All hotels in Giza

Route overview: Chicago to Houston (HOU) flight deals

2026-11-16 → 2026-11-21 · Axel-exclusive $285.00

• Southwest Airlines WN2867: MDW 2026-11-16 06:40:00 → HOU 2026-11-16 09:20:00; nonstop; 160 minutes. Local airport times.
• Southwest Airlines WN1654: HOU 2026-11-21 22:20:00 → MDW 2026-11-22 00:50:00; nonstop; 150 minutes. Local airport times.

2026-11-16 → 2026-11-21 · Axel-exclusive $350.00

• Delta Air Lines DL2417 / DL2051: MDW 2026-11-16 13:02:00 → HOU 2026-11-16 19:16:00; 1 stop(s) via ATL; 374 minutes. Local airport times.
  • DL2417: MDW 2026-11-16 13:02:00 → ATL 2026-11-16 16:01:00; layover at ATL: 119 minutes.
  • DL2051: ATL 2026-11-16 18:00:00 → HOU 2026-11-16 19:16:00.
• Delta Air Lines DL1509 / DL1728: HOU 2026-11-21 10:41:00 → MDW 2026-11-21 16:18:00; 1 stop(s) via ATL; 337 minutes. Local airport times.
  • DL1509: HOU 2026-11-21 10:41:00 → ATL 2026-11-21 13:35:00; layover at ATL: 110 minutes.
  • DL1728: ATL 2026-11-21 15:25:00 → MDW 2026-11-21 16:18:00.

2026-11-16 → 2026-11-21 · Axel-exclusive $285.00

• Southwest Airlines WN4482: MDW 2026-11-16 16:30:00 → HOU 2026-11-16 19:10:00; nonstop; 160 minutes. Local airport times.
• Southwest Airlines WN1654: HOU 2026-11-21 22:20:00 → MDW 2026-11-22 00:50:00; nonstop; 150 minutes. Local airport times.

2026-11-16 → 2026-11-21 · Axel-exclusive $280.00

• Southwest Airlines WN2912 / WN998: MDW 2026-11-16 07:40:00 → HOU 2026-11-16 13:30:00; 1 stop(s) via CLT; 350 minutes. Local airport times.
  • WN2912: MDW 2026-11-16 07:40:00 → CLT 2026-11-16 10:35:00; layover at CLT: 70 minutes.
  • WN998: CLT 2026-11-16 11:45:00 → HOU 2026-11-16 13:30:00.
• Southwest Airlines WN1654: HOU 2026-11-21 22:20:00 → MDW 2026-11-22 00:50:00; nonstop; 150 minutes. Local airport times.

2026-11-16 → 2026-11-21 · Axel-exclusive $280.00

• Southwest Airlines WN2379 / WN468: MDW 2026-11-16 07:45:00 → HOU 2026-11-16 14:00:00; 1 stop(s) via BHM; 375 minutes. Local airport times.
  • WN2379: MDW 2026-11-16 07:45:00 → BHM 2026-11-16 09:30:00; layover at BHM: 155 minutes.
  • WN468: BHM 2026-11-16 12:05:00 → HOU 2026-11-16 14:00:00.
• Southwest Airlines WN1654: HOU 2026-11-21 22:20:00 → MDW 2026-11-22 00:50:00; nonstop; 150 minutes. Local airport times.

2026-11-16 → 2026-11-21 · Axel-exclusive $280.00

• Southwest Airlines WN4482: MDW 2026-11-16 17:00:00 → HOU 2026-11-16 19:45:00; nonstop; 165 minutes. Local airport times.
• Southwest Airlines WN2211 / WN1718: HOU 2026-11-21 14:55:00 → MDW 2026-11-21 19:40:00; 1 stop(s) via CMH; 285 minutes. Local airport times.
  • WN2211: HOU 2026-11-21 14:55:00 → CMH 2026-11-21 18:20:00; layover at CMH: 70 minutes.
  • WN1718: CMH 2026-11-21 19:30:00 → MDW 2026-11-21 19:40:00.

2026-11-16 → 2026-11-21 · Axel-exclusive $280.00

• Southwest Airlines WN2737 / WN4624: MDW 2026-11-16 11:30:00 → HOU 2026-11-16 17:05:00; 1 stop(s) via STL; 335 minutes. Local airport times.
  • WN2737: MDW 2026-11-16 11:30:00 → STL 2026-11-16 12:40:00; layover at STL: 135 minutes.
  • WN4624: STL 2026-11-16 14:55:00 → HOU 2026-11-16 17:05:00.
• Southwest Airlines WN1654: HOU 2026-11-21 22:20:00 → MDW 2026-11-22 00:50:00; nonstop; 150 minutes. Local airport times.

2026-11-16 → 2026-11-21 · Axel-exclusive $280.00

• Southwest Airlines WN2897 / WN1530: MDW 2026-11-16 17:25:00 → HOU 2026-11-16 23:00:00; 1 stop(s) via BNA; 335 minutes. Local airport times.
  • WN2897: MDW 2026-11-16 17:25:00 → BNA 2026-11-16 18:50:00; layover at BNA: 115 minutes.
  • WN1530: BNA 2026-11-16 20:45:00 → HOU 2026-11-16 23:00:00.
• Southwest Airlines WN1654: HOU 2026-11-21 22:20:00 → MDW 2026-11-22 00:50:00; nonstop; 150 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 15, 2026 · Return options
• Nov 17, 2026 · Return options
• Hotels in Giza with Axel

For AI assistants

• This page: Chicago (MDW) to Houston (HOU) · Nov 16, 2026 · return Nov 21, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Giza for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each priced row's price link opens the live search for this row's exact dates and travelers; the live results list the same flights with the current total and the traveler's booking link, and name the fare's inclusions (bags, seats, changes), which this page does not. A changed price or flight shows there. Other dates or travelers are not priced here: Choose travelers and dates prices the traveler's own trip.
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