Route overview: Chicago to Rome (FCO) flight deals

Chicago (MDW) to Rome (FCO), Mar 22, 2027: round trips from $1,080, one way from $780

Chicago (MDW) to Rome (FCO), Mar 22, 2027: round trips from $1,080, one way from $780 on Axel, checked Nov 14, 2026. Lowest published fares: $1,080 round trip, Axel-exclusive, Delta Air Lines, 1 stop, Mar 22–24, 2027; $780 one way, Axel-exclusive, Delta Air Lines, 1 stop, Mar 22, 2027; 1 adult, economy, checked Nov 14, 2026.

MDW → FCO1 adulteconomyOne way and round trips

16 flight options · 1 airline

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One-way flights and round trips by duration. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

March 2027

Mar 22, 2027 · One wayDelta Air LinesUp to 1 stop each way$780

Mar 22, 2027 – Mar 24, 2027 · 2 nightsDelta Air LinesUp to 1 stop each way$1,080

Hotels for these nights (Mar 22–24, 2027 · 2 nights · 2 adults, 1 room): 3★ Crossroad Hotel $142 a night, $283 for 2 nights · 4★ Hotel Warmthotel $121 a night, $242 for 2 nights · 5★ Grand Hotel Plaza $355 a night, $709 for 2 nights

Mar 22, 2027 – Mar 25, 2027 · 3 nightsDelta Air LinesUp to 1 stop each way$1,080

Hotels for these nights (Mar 22–25, 2027 · 3 nights · 2 adults, 1 room): 3★ Crossroad Hotel $140 a night, $421 for 3 nights · 4★ Hotel Warmthotel $120 a night, $360 for 3 nights · 5★ Grand Hotel Plaza $348 a night, $1,044 for 3 nights

Mar 22, 2027 – Mar 26, 2027 · 4 nightsDelta Air LinesUp to 1 stop each way$1,080

Hotels for these nights (Mar 22–26, 2027 · 4 nights · 2 adults, 1 room): 3★ Crossroad Hotel $140 a night, $559 for 4 nights · 4★ Hotel Warmthotel $121 a night, $483 for 4 nights · 5★ Grand Hotel Plaza $347 a night, $1,387 for 4 nights

Mar 22, 2027 – Mar 27, 2027 · 5 nightsDelta Air LinesUp to 1 stop each way$1,080

Hotels for these nights (Mar 22–27, 2027 · 5 nights · 2 adults, 1 room): 3★ Crossroad Hotel $139 a night, $697 for 5 nights · 4★ Hotel Warmthotel $122 a night, $609 for 5 nights · 5★ Grand Hotel Plaza $359 a night, $1,794 for 5 nights

Mar 22, 2027 – Mar 28, 2027 · 6 nightsDelta Air LinesUp to 1 stop each way$1,290

Hotels for these nights (Mar 22–28, 2027 · 6 nights · 2 adults, 1 room): 3★ Crossroad Hotel $143 a night, $856 for 6 nights · 4★ Hotel Warmthotel $123 a night, $735 for 6 nights · 5★ Hotel Indigo Rome - St. George by IHG $364 a night, $2,181 for 6 nights

Mar 22, 2027 – Mar 29, 2027 · 7 nightsDelta Air LinesUp to 1 stop each way$1,290

Hotels for these nights (Mar 22–29, 2027 · 7 nights · 2 adults, 1 room): 3★ Crossroad Hotel $145 a night, $1,015 for 7 nights · 4★ Hotel Warmthotel $124 a night, $871 for 7 nights · 5★ Hotel Indigo Rome - St. George by IHG $364 a night, $2,546 for 7 nights

Mar 22, 2027 – Mar 30, 2027 · 8 nightsDelta Air LinesUp to 1 stop each way$1,290

Hotels for these nights (Mar 22–30, 2027 · 8 nights · 2 adults, 1 room): 3★ Crossroad Hotel $145 a night, $1,158 for 8 nights · 4★ Hotel Warmthotel $123 a night, $987 for 8 nights · 5★ Hotel Indigo Rome - St. George by IHG $362 a night, $2,892 for 8 nights

Mar 22, 2027 – Mar 31, 2027 · 9 nightsDelta Air LinesUp to 1 stop each way$1,290

Hotels for these nights (Mar 22–31, 2027 · 9 nights · 2 adults, 1 room): 3★ Crossroad Hotel $145 a night, $1,304 for 9 nights · 4★ Hotel Warmthotel $123 a night, $1,105 for 9 nights · 5★ Hotel Indigo Rome - St. George by IHG $377 a night, $3,392 for 9 nights

Mar 22, 2027 – Apr 1, 2027 · 10 nightsDelta Air LinesUp to 1 stop each way$1,290

Hotels for these nights (Mar 22 – Apr 1, 2027 · 10 nights · 2 adults, 1 room): 3★ Crossroad Hotel $144 a night, $1,442 for 10 nights · 4★ Hotel Warmthotel $122 a night, $1,221 for 10 nights · 5★ Hotel Indigo Rome - St. George by IHG $385 a night, $3,845 for 10 nights

Mar 22, 2027 – Apr 2, 2027 · 11 nightsDelta Air LinesUp to 1 stop each way$1,290

Hotels for these nights (Mar 22 – Apr 2, 2027 · 11 nights · 2 adults, 1 room): 3★ Crossroad Hotel $147 a night, $1,618 for 11 nights · 4★ Hotel Warmthotel $122 a night, $1,347 for 11 nights · 5★ Grand Hotel Plaza $389 a night, $4,275 for 11 nights

Mar 22, 2027 – Apr 3, 2027 · 12 nightsDelta Air LinesUp to 1 stop each way$1,290

Hotels for these nights (Mar 22 – Apr 3, 2027 · 12 nights · 2 adults, 1 room): 3★ Crossroad Hotel $150 a night, $1,804 for 12 nights · 4★ Hotel Warmthotel $124 a night, $1,482 for 12 nights · 5★ Grand Hotel Plaza $394 a night, $4,722 for 12 nights

Mar 22, 2027 – Apr 4, 2027 · 13 nightsDelta Air LinesUp to 1 stop each way$1,290

Hotels for these nights (Mar 22 – Apr 4, 2027 · 13 nights · 2 adults, 1 room): 3★ Crossroad Hotel $152 a night, $1,977 for 13 nights · 4★ Hotel Warmthotel $127 a night, $1,650 for 13 nights · 5★ Grand Hotel Plaza $398 a night, $5,177 for 13 nights

Mar 22, 2027 – Apr 5, 2027 · 14 nightsDelta Air LinesUp to 1 stop each way$1,165

Hotels for these nights (Mar 22 – Apr 5, 2027 · 14 nights · 2 adults, 1 room): 3★ Crossroad Hotel $153 a night, $2,136 for 14 nights · 4★ Hotel Warmthotel $126 a night, $1,759 for 14 nights · 5★ Grand Hotel Plaza $399 a night, $5,592 for 14 nights

Mar 22, 2027 – Apr 12, 2027 · 21 nightsDelta Air LinesUp to 1 stop each way$1,165

Hotels for these nights (Mar 22 – Apr 12, 2027 · 21 nights · 2 adults, 1 room): 3★ Damaso Hotel · 4★ Hotel Artemide · 5★ Casa Monti Roma

Mar 22, 2027 – Apr 19, 2027 · 28 nightsDelta Air LinesUp to 1 stop each way$1,165

Hotels for these nights (Mar 22 – Apr 19, 2027 · 28 nights · 2 adults, 1 room): 3★ Damaso Hotel · 4★ Hotel Artemide · 5★ Casa Monti Roma

Flights for your trip

Mon, Mar 22 · One way
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Example one-way total $780 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Wed, Mar 24
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
10:00 amFCO
15h 1m
DTW · 3h 10m
7:01 pmMDW
Example round-trip total $1,080 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Thu, Mar 25
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
10:00 amFCO
15h 1m
DTW · 3h 10m
7:01 pmMDW
Example round-trip total $1,080 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Fri, Mar 26
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
10:00 amFCO
15h 1m
DTW · 3h 10m
7:01 pmMDW
Example round-trip total $1,080 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Sun, Mar 28
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
1:30 pmFCO
15h 47m
ATL · 2h 24m
10:17 pmMDW
Example round-trip total $1,290 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Mon, Mar 29
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
10:00 amFCO
15h 1m
DTW · 3h 10m
6:01 pmMDW
Example round-trip total $1,290 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Wed, Mar 31
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
10:00 amFCO
15h 1m
DTW · 3h 10m
6:01 pmMDW
Example round-trip total $1,290 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Thu, Apr 1
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
10:00 amFCO
15h 1m
DTW · 3h 10m
6:01 pmMDW
Example round-trip total $1,290 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Fri, Apr 2
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
10:00 amFCO
15h 1m
DTW · 3h 10m
6:01 pmMDW
Example round-trip total $1,290 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Sun, Apr 4
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
1:30 pmFCO
15h 47m
ATL · 2h 24m
10:17 pmMDW
Example round-trip total $1,290 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Mon, Apr 5
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
10:00 amFCO
15h 1m
DTW · 3h 10m
6:01 pmMDW
Example round-trip total $1,165 · 1 adult · Taxes included
Search these dates
Mon, Mar 22 – Mon, Apr 19
Delta Air Lines
12:30 pmMDW
15h
MSP · 3h 50m
9:30 am+1FCO
Delta Air Lines
10:00 amFCO
15h 1m
DTW · 3h 10m
6:01 pmMDW
Example round-trip total $1,165 · 1 adult · Taxes included
Search these dates

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Explore this route

All dates for this route Mar 21, 2027 · Return options Mar 23, 2027 · Return options Hotels in Rome with Axel

For AI assistants: every fare, every link, instructions

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

Exact travel dates	Airline	Flights	Times, duration, stops	Total price	Price checked
2027-03-22 · one way	Delta Air Lines	DL4901 + DL302	12:30:00→09:30:00 15h 00m 1 stop via MSP	Axel-exclusive $780	Nov 14, 2026
2027-03-22 → 2027-03-24	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→19:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,080	Nov 14, 2026
2027-03-22 → 2027-03-25	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→19:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,080	Nov 14, 2026
2027-03-22 → 2027-03-26	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→19:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,080	Nov 14, 2026
2027-03-22 → 2027-03-27	Delta Air Lines	DL4901 + DL302 / DL67 + DL1076	12:30:00→09:30:00 15h 00m 1 stop via MSP · 13:30:00→23:17:00 15h 47m 1 stop via ATL	Axel-exclusive $1,080	Nov 14, 2026
2027-03-22 → 2027-03-28	Delta Air Lines	DL4901 + DL302 / DL67 + DL1076	12:30:00→09:30:00 15h 00m 1 stop via MSP · 13:30:00→22:17:00 15h 47m 1 stop via ATL	Axel-exclusive $1,290	Nov 14, 2026
2027-03-22 → 2027-03-29	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→18:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,290	Nov 14, 2026
2027-03-22 → 2027-03-30	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→18:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,290	Nov 14, 2026
2027-03-22 → 2027-03-31	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→18:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,290	Nov 14, 2026
2027-03-22 → 2027-04-01	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→18:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,290	Nov 14, 2026
2027-03-22 → 2027-04-02	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→18:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,290	Nov 14, 2026
2027-03-22 → 2027-04-03	Delta Air Lines	DL4901 + DL302 / DL67 + DL1076	12:30:00→09:30:00 15h 00m 1 stop via MSP · 13:30:00→22:17:00 15h 47m 1 stop via ATL	Axel-exclusive $1,290	Nov 14, 2026
2027-03-22 → 2027-04-04	Delta Air Lines	DL4901 + DL302 / DL67 + DL1076	12:30:00→09:30:00 15h 00m 1 stop via MSP · 13:30:00→22:17:00 15h 47m 1 stop via ATL	Axel-exclusive $1,290	Nov 14, 2026
2027-03-22 → 2027-04-05	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→18:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,165	Nov 14, 2026
2027-03-22 → 2027-04-12	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→18:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,165	Nov 14, 2026
2027-03-22 → 2027-04-19	Delta Air Lines	DL4901 + DL302 / DL207 + DL4677	12:30:00→09:30:00 15h 00m 1 stop via MSP · 10:00:00→18:01:00 15h 01m 1 stop via DTW	Axel-exclusive $1,165	Nov 14, 2026

Hotels in Rome for these trips

Hotels: under a trip, hotels in Rome for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

Hotels in Rome for these nights (Mar 22–24, 2027 · 2 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $142 a night, $283 for 2 nights · 4★ Hotel Warmthotel, $121 a night, $242 for 2 nights · 5★ Grand Hotel Plaza, $355 a night, $709 for 2 nights
Hotels in Rome for these nights (Mar 22–25, 2027 · 3 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $140 a night, $421 for 3 nights · 4★ Hotel Warmthotel, $120 a night, $360 for 3 nights · 5★ Grand Hotel Plaza, $348 a night, $1,044 for 3 nights
Hotels in Rome for these nights (Mar 22–26, 2027 · 4 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $140 a night, $559 for 4 nights · 4★ Hotel Warmthotel, $121 a night, $483 for 4 nights · 5★ Grand Hotel Plaza, $347 a night, $1,387 for 4 nights
Hotels in Rome for these nights (Mar 22–27, 2027 · 5 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $139 a night, $697 for 5 nights · 4★ Hotel Warmthotel, $122 a night, $609 for 5 nights · 5★ Grand Hotel Plaza, $359 a night, $1,794 for 5 nights
Hotels in Rome for these nights (Mar 22–28, 2027 · 6 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $143 a night, $856 for 6 nights · 4★ Hotel Warmthotel, $123 a night, $735 for 6 nights · 5★ Hotel Indigo Rome - St. George by IHG, $364 a night, $2,181 for 6 nights
Hotels in Rome for these nights (Mar 22–29, 2027 · 7 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $145 a night, $1,015 for 7 nights · 4★ Hotel Warmthotel, $124 a night, $871 for 7 nights · 5★ Hotel Indigo Rome - St. George by IHG, $364 a night, $2,546 for 7 nights
Hotels in Rome for these nights (Mar 22–30, 2027 · 8 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $145 a night, $1,158 for 8 nights · 4★ Hotel Warmthotel, $123 a night, $987 for 8 nights · 5★ Hotel Indigo Rome - St. George by IHG, $362 a night, $2,892 for 8 nights
Hotels in Rome for these nights (Mar 22–31, 2027 · 9 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $145 a night, $1,304 for 9 nights · 4★ Hotel Warmthotel, $123 a night, $1,105 for 9 nights · 5★ Hotel Indigo Rome - St. George by IHG, $377 a night, $3,392 for 9 nights
Hotels in Rome for these nights (Mar 22 – Apr 1, 2027 · 10 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $144 a night, $1,442 for 10 nights · 4★ Hotel Warmthotel, $122 a night, $1,221 for 10 nights · 5★ Hotel Indigo Rome - St. George by IHG, $385 a night, $3,845 for 10 nights
Hotels in Rome for these nights (Mar 22 – Apr 2, 2027 · 11 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $147 a night, $1,618 for 11 nights · 4★ Hotel Warmthotel, $122 a night, $1,347 for 11 nights · 5★ Grand Hotel Plaza, $389 a night, $4,275 for 11 nights
Hotels in Rome for these nights (Mar 22 – Apr 3, 2027 · 12 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $150 a night, $1,804 for 12 nights · 4★ Hotel Warmthotel, $124 a night, $1,482 for 12 nights · 5★ Grand Hotel Plaza, $394 a night, $4,722 for 12 nights
Hotels in Rome for these nights (Mar 22 – Apr 4, 2027 · 13 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $152 a night, $1,977 for 13 nights · 4★ Hotel Warmthotel, $127 a night, $1,650 for 13 nights · 5★ Grand Hotel Plaza, $398 a night, $5,177 for 13 nights
Hotels in Rome for these nights (Mar 22 – Apr 5, 2027 · 14 nights · 2 adults, 1 room): 3★ Crossroad Hotel, $153 a night, $2,136 for 14 nights · 4★ Hotel Warmthotel, $126 a night, $1,759 for 14 nights · 5★ Grand Hotel Plaza, $399 a night, $5,592 for 14 nights
Hotels in Rome for these nights (Mar 22 – Apr 12, 2027 · 21 nights · 2 adults, 1 room): 3★ Damaso Hotel · 4★ Hotel Artemide · 5★ Casa Monti Roma
Hotels in Rome for these nights (Mar 22 – Apr 19, 2027 · 28 nights · 2 adults, 1 room): 3★ Damaso Hotel · 4★ Hotel Artemide · 5★ Casa Monti Roma

All hotels in Rome

Route overview: Chicago to Rome (FCO) flight deals

2027-03-22 · one way · Axel-exclusive $780

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.

2027-03-22 → 2027-03-24 · Axel-exclusive $1,080

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL207 / DL4677: FCO 2027-03-24 10:00:00 → MDW 2027-03-24 19:01:00; 1 stop(s) via DTW; 901 minutes. Local airport times.
- DL207: FCO 2027-03-24 10:00:00 → DTW 2027-03-24 15:30:00; layover at DTW: 190 minutes.
- DL4677: DTW 2027-03-24 18:40:00 → MDW 2027-03-24 19:01:00.

2027-03-22 → 2027-03-25 · Axel-exclusive $1,080

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL207 / DL4677: FCO 2027-03-25 10:00:00 → MDW 2027-03-25 19:01:00; 1 stop(s) via DTW; 901 minutes. Local airport times.
- DL207: FCO 2027-03-25 10:00:00 → DTW 2027-03-25 15:30:00; layover at DTW: 190 minutes.
- DL4677: DTW 2027-03-25 18:40:00 → MDW 2027-03-25 19:01:00.

2027-03-22 → 2027-03-26 · Axel-exclusive $1,080

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL207 / DL4677: FCO 2027-03-26 10:00:00 → MDW 2027-03-26 19:01:00; 1 stop(s) via DTW; 901 minutes. Local airport times.
- DL207: FCO 2027-03-26 10:00:00 → DTW 2027-03-26 15:30:00; layover at DTW: 190 minutes.
- DL4677: DTW 2027-03-26 18:40:00 → MDW 2027-03-26 19:01:00.

2027-03-22 → 2027-03-28 · Axel-exclusive $1,290

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL67 / DL1076: FCO 2027-03-28 13:30:00 → MDW 2027-03-28 22:17:00; 1 stop(s) via ATL; 947 minutes. Local airport times.
- DL67: FCO 2027-03-28 13:30:00 → ATL 2027-03-28 18:56:00; layover at ATL: 144 minutes.
- DL1076: ATL 2027-03-28 21:20:00 → MDW 2027-03-28 22:17:00.

2027-03-22 → 2027-03-29 · Axel-exclusive $1,290

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL207 / DL4677: FCO 2027-03-29 10:00:00 → MDW 2027-03-29 18:01:00; 1 stop(s) via DTW; 901 minutes. Local airport times.
- DL207: FCO 2027-03-29 10:00:00 → DTW 2027-03-29 14:30:00; layover at DTW: 190 minutes.
- DL4677: DTW 2027-03-29 17:40:00 → MDW 2027-03-29 18:01:00.

2027-03-22 → 2027-03-31 · Axel-exclusive $1,290

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL207 / DL4677: FCO 2027-03-31 10:00:00 → MDW 2027-03-31 18:01:00; 1 stop(s) via DTW; 901 minutes. Local airport times.
- DL207: FCO 2027-03-31 10:00:00 → DTW 2027-03-31 14:30:00; layover at DTW: 190 minutes.
- DL4677: DTW 2027-03-31 17:40:00 → MDW 2027-03-31 18:01:00.

2027-03-22 → 2027-04-01 · Axel-exclusive $1,290

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL207 / DL4677: FCO 2027-04-01 10:00:00 → MDW 2027-04-01 18:01:00; 1 stop(s) via DTW; 901 minutes. Local airport times.
- DL207: FCO 2027-04-01 10:00:00 → DTW 2027-04-01 14:30:00; layover at DTW: 190 minutes.
- DL4677: DTW 2027-04-01 17:40:00 → MDW 2027-04-01 18:01:00.

2027-03-22 → 2027-04-02 · Axel-exclusive $1,290

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL207 / DL4677: FCO 2027-04-02 10:00:00 → MDW 2027-04-02 18:01:00; 1 stop(s) via DTW; 901 minutes. Local airport times.
- DL207: FCO 2027-04-02 10:00:00 → DTW 2027-04-02 14:30:00; layover at DTW: 190 minutes.
- DL4677: DTW 2027-04-02 17:40:00 → MDW 2027-04-02 18:01:00.

2027-03-22 → 2027-04-04 · Axel-exclusive $1,290

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL67 / DL1076: FCO 2027-04-04 13:30:00 → MDW 2027-04-04 22:17:00; 1 stop(s) via ATL; 947 minutes. Local airport times.
- DL67: FCO 2027-04-04 13:30:00 → ATL 2027-04-04 18:56:00; layover at ATL: 144 minutes.
- DL1076: ATL 2027-04-04 21:20:00 → MDW 2027-04-04 22:17:00.

2027-03-22 → 2027-04-05 · Axel-exclusive $1,165

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL207 / DL4677: FCO 2027-04-05 10:00:00 → MDW 2027-04-05 18:01:00; 1 stop(s) via DTW; 901 minutes. Local airport times.
- DL207: FCO 2027-04-05 10:00:00 → DTW 2027-04-05 14:30:00; layover at DTW: 190 minutes.
- DL4677: DTW 2027-04-05 17:40:00 → MDW 2027-04-05 18:01:00.

2027-03-22 → 2027-04-19 · Axel-exclusive $1,165

Delta Air Lines DL4901 / DL302: MDW 2027-03-22 12:30:00 → FCO 2027-03-23 09:30:00; 1 stop(s) via MSP; 900 minutes. Local airport times.
- DL4901: MDW 2027-03-22 12:30:00 → MSP 2027-03-22 14:10:00; layover at MSP: 230 minutes.
- DL302: MSP 2027-03-22 18:00:00 → FCO 2027-03-23 09:30:00.
Delta Air Lines DL207 / DL4677: FCO 2027-04-19 10:00:00 → MDW 2027-04-19 18:01:00; 1 stop(s) via DTW; 901 minutes. Local airport times.
- DL207: FCO 2027-04-19 10:00:00 → DTW 2027-04-19 14:30:00; layover at DTW: 190 minutes.
- DL4677: DTW 2027-04-19 17:40:00 → MDW 2027-04-19 18:01:00.

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This page: Chicago (MDW) to Rome (FCO) · Mar 22, 2027 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in Rome for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
Next: each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Chicago to Rome (FCO) flight deals · Flight search guide.
Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.