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Chicago → Buffalo

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MDW → BUF1 adulteconomy

9 flight options · 2 airlines

Round-trip flights

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
7:40 amMDW
1h 25m
Nonstop
10:05 amBUF
Southwest Airlines
8:00 amBUF
1h 50m
Nonstop
8:50 amMDW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Delta Air Lines
1:31 pmMDW
4h 42m
DTW · 2h 12m
7:13 pmBUF
Delta Air Lines
6:35 amBUF
4h 11m
DTW · 1h 18m
9:46 amMDW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
1:25 pmMDW
1h 35m
Nonstop
4:00 pmBUF
Southwest Airlines
6:55 pmBUF
1h 50m
Nonstop
7:45 pmMDW

Round-trip total · 1 adult · Taxes included

Fri, Nov 20 – Mon, Nov 23

Southwest Airlines
1:25 pmMDW
1h 35m
Nonstop
4:00 pmBUF
Southwest Airlines
8:00 amBUF
1h 50m
Nonstop
8:50 amMDW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Southwest Airlines
7:40 amMDW
1h 25m
Nonstop
10:05 amBUF
Southwest Airlines
6:55 pmBUF
1h 50m
Nonstop
7:45 pmMDW

Round-trip total · 1 adult · Taxes included

Fri, Nov 27 – Fri, Dec 4

Delta Air Lines
1:31 pmMDW
4h 42m
DTW · 2h 12m
7:13 pmBUF
Delta Air Lines
6:35 amBUF
4h 11m
DTW · 1h 18m
9:46 amMDW

Round-trip total · 1 adult · Taxes included

One-way flights

Fri, Nov 20 · One way

Southwest Airlines
1:25 pmMDW
1h 35m
Nonstop
4:00 pmBUF

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Delta Air Lines
1:31 pmMDW
4h 42m
DTW · 2h 12m
7:13 pmBUF

One-way total · 1 adult · Taxes included

Fri, Nov 20 · One way

Southwest Airlines
7:40 amMDW
1h 25m
Nonstop
10:05 amBUF

One-way total · 1 adult · Taxes included

Make this trip yours

MDW ⇄ BUF

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Why book with Axel
  • A real airline bookingThe booking is in the airline’s own system under your name. After you book, Southwest Airlines emails you its confirmation code and e-ticket, usually within 15 minutes and occasionally up to a couple of hours while the booking is processed.
  • Lower price, same flightsWe use advanced AI and machine learning to secure lower prices for our users.
  • 24-hour cancellationCancel within 24 hours of booking for a full refund when your departure is at least 7 days away. Closer to departure, the airline’s fare rules apply. Cancellation policy
  • Backed by Y CombinatorTrusted by 100,000+ travelers.

Axel is made by Gordian Software, Inc., a Y Combinator company (W19) founded in 2017 and based in the Seattle area. The company is led by CEO Stephen Grabowski, formerly of Skyscanner. How Axel works · About

More dates

Nov 20, 2026 → Nov 23, 2026Nov 27, 2026 → Dec 4, 2026Nov 20, 2026 · One way
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-11-20 · one waySouthwest AirlinesWN1417$135.002026-10-29T01:29:05Z
2026-11-20 → 2026-11-23Southwest AirlinesWN1051 / WN1626$260.002026-10-29T01:29:05Z
2026-11-20 · one wayDelta Air LinesDL4688 + DL3843$165.002026-10-29T01:29:05Z
2026-11-20 → 2026-11-23Delta Air LinesDL4688 + DL3843 / DL1721 + DL4684$315.002026-10-29T01:29:05Z
2026-11-27 → 2026-12-04Southwest AirlinesWN1417 / WN383$305.502026-10-29T01:29:05Z
2026-11-20 · one waySouthwest AirlinesWN1051$135.002026-10-29T01:29:05Z
2026-11-20 → 2026-11-23Southwest AirlinesWN1417 / WN1626$260.002026-10-29T01:29:05Z
2026-11-27 → 2026-12-04Southwest AirlinesWN1051 / WN383$305.502026-10-29T01:29:05Z
2026-11-27 → 2026-12-04Delta Air LinesDL4688 + DL3843 / DL1721 + DL4684$370.132026-10-29T01:29:05Z

2026-11-20 · one way · $135.00

  • Southwest Airlines WN1417: MDW 2026-11-20 13:25:00 → BUF 2026-11-20 16:00:00; nonstop; 95 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $260.00

  • Southwest Airlines WN1051: MDW 2026-11-20 07:40:00 → BUF 2026-11-20 10:05:00; nonstop; 85 minutes. Local airport times.
  • Southwest Airlines WN1626: BUF 2026-11-23 08:00:00 → MDW 2026-11-23 08:50:00; nonstop; 110 minutes. Local airport times.

2026-11-20 · one way · $165.00

  • Delta Air Lines DL4688 / DL3843: MDW 2026-11-20 13:31:00 → BUF 2026-11-20 19:13:00; 1 stop(s) via DTW; 282 minutes. Local airport times.
    • DL4688: MDW 2026-11-20 13:31:00 → DTW 2026-11-20 15:44:00; layover at DTW: 132 minutes.
    • DL3843: DTW 2026-11-20 17:56:00 → BUF 2026-11-20 19:13:00.

2026-11-20 → 2026-11-23 · $315.00

  • Delta Air Lines DL4688 / DL3843: MDW 2026-11-20 13:31:00 → BUF 2026-11-20 19:13:00; 1 stop(s) via DTW; 282 minutes. Local airport times.
    • DL4688: MDW 2026-11-20 13:31:00 → DTW 2026-11-20 15:44:00; layover at DTW: 132 minutes.
    • DL3843: DTW 2026-11-20 17:56:00 → BUF 2026-11-20 19:13:00.
  • Delta Air Lines DL1721 / DL4684: BUF 2026-11-23 06:35:00 → MDW 2026-11-23 09:46:00; 1 stop(s) via DTW; 251 minutes. Local airport times.
    • DL1721: BUF 2026-11-23 06:35:00 → DTW 2026-11-23 07:52:00; layover at DTW: 78 minutes.
    • DL4684: DTW 2026-11-23 09:10:00 → MDW 2026-11-23 09:46:00.

2026-11-27 → 2026-12-04 · $305.50

  • Southwest Airlines WN1417: MDW 2026-11-27 13:25:00 → BUF 2026-11-27 16:00:00; nonstop; 95 minutes. Local airport times.
  • Southwest Airlines WN383: BUF 2026-12-04 18:55:00 → MDW 2026-12-04 19:45:00; nonstop; 110 minutes. Local airport times.

2026-11-20 · one way · $135.00

  • Southwest Airlines WN1051: MDW 2026-11-20 07:40:00 → BUF 2026-11-20 10:05:00; nonstop; 85 minutes. Local airport times.

2026-11-20 → 2026-11-23 · $260.00

  • Southwest Airlines WN1417: MDW 2026-11-20 13:25:00 → BUF 2026-11-20 16:00:00; nonstop; 95 minutes. Local airport times.
  • Southwest Airlines WN1626: BUF 2026-11-23 08:00:00 → MDW 2026-11-23 08:50:00; nonstop; 110 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $305.50

  • Southwest Airlines WN1051: MDW 2026-11-27 07:40:00 → BUF 2026-11-27 10:05:00; nonstop; 85 minutes. Local airport times.
  • Southwest Airlines WN383: BUF 2026-12-04 18:55:00 → MDW 2026-12-04 19:45:00; nonstop; 110 minutes. Local airport times.

2026-11-27 → 2026-12-04 · $370.13

  • Delta Air Lines DL4688 / DL3843: MDW 2026-11-27 13:31:00 → BUF 2026-11-27 19:13:00; 1 stop(s) via DTW; 282 minutes. Local airport times.
    • DL4688: MDW 2026-11-27 13:31:00 → DTW 2026-11-27 15:44:00; layover at DTW: 132 minutes.
    • DL3843: DTW 2026-11-27 17:56:00 → BUF 2026-11-27 19:13:00.
  • Delta Air Lines DL1721 / DL4684: BUF 2026-12-04 06:35:00 → MDW 2026-12-04 09:46:00; 1 stop(s) via DTW; 251 minutes. Local airport times.
    • DL1721: BUF 2026-12-04 06:35:00 → DTW 2026-12-04 07:52:00; layover at DTW: 78 minutes.
    • DL4684: DTW 2026-12-04 09:10:00 → MDW 2026-12-04 09:46:00.

More dates for this route