Jacksonville (JAX) to Saint Louis (STL), Nov 30, 2026: round trips from $385, one way from $228

Jacksonville (JAX) to Saint Louis (STL), Nov 30, 2026: round trips from $385, one way from $228 on Axel, checked Nov 11, 2026. Lowest published fares: $385 round trip, Axel-exclusive, Southwest Airlines, nonstop, Nov 30, 2026 – Dec 1, 2026; $228 one way, Axel-exclusive, Southwest Airlines, nonstop, Nov 30, 2026; 1 adult, economy, checked Nov 11, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in St. Louis for these nights (Nov 30 – Dec 1, 2026 · 1 night · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $54 a night · 4★ Hilton St. Louis at the Ballpark, $104 a night · 5★ Four Seasons Hotel St Louis, $366 a night
• Hotels in St. Louis for these nights (Nov 30 – Dec 2, 2026 · 2 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $64 a night, $128 for 2 nights · 4★ Hilton St. Louis at the Ballpark, $105 a night, $209 for 2 nights · 5★ Four Seasons Hotel St Louis, $366 a night, $732 for 2 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 3, 2026 · 3 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $63 a night, $189 for 3 nights · 4★ Hilton St. Louis at the Ballpark, $105 a night, $314 for 3 nights · 5★ Four Seasons Hotel St Louis, $366 a night, $1,098 for 3 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 4, 2026 · 4 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $63 a night, $253 for 4 nights · 4★ Hilton St. Louis at the Ballpark, $105 a night, $419 for 4 nights · 5★ Four Seasons Hotel St Louis, $412 a night, $1,648 for 4 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 5, 2026 · 5 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $65 a night, $326 for 5 nights · 4★ CozySuites Central West End, $145 a night, $724 for 5 nights · 5★ Four Seasons Hotel St Louis, $430 a night, $2,150 for 5 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 6, 2026 · 6 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $67 a night, $401 for 6 nights · 4★ CozySuites Central West End, $149 a night, $892 for 6 nights · 5★ Four Seasons Hotel St Louis, $431 a night, $2,584 for 6 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 7, 2026 · 7 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $66 a night, $463 for 7 nights · 4★ CozySuites Central West End, $146 a night, $1,019 for 7 nights · 5★ Four Seasons Hotel St Louis, $421 a night, $2,950 for 7 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 8, 2026 · 8 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $67 a night, $537 for 8 nights · 4★ CozySuites Central West End, $143 a night, $1,146 for 8 nights · 5★ Four Seasons Hotel St Louis, $415 a night, $3,316 for 8 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 9, 2026 · 9 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $67 a night, $601 for 9 nights · 4★ CozySuites Central West End, $141 a night, $1,271 for 9 nights · 5★ Four Seasons Hotel St Louis, $409 a night, $3,682 for 9 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 10, 2026 · 10 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $68 a night, $675 for 10 nights · 4★ CozySuites Central West End, $139 a night, $1,394 for 10 nights · 5★ Four Seasons Hotel St Louis, $405 a night, $4,048 for 10 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 11, 2026 · 11 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $67 a night, $740 for 11 nights · 4★ CozySuites Central West End, $140 a night, $1,539 for 11 nights · 5★ Four Seasons Hotel St Louis, $401 a night, $4,414 for 11 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 12, 2026 · 12 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $68 a night, $814 for 12 nights · 4★ CozySuites Central West End, $140 a night, $1,684 for 12 nights · 5★ Four Seasons Hotel St Louis, $398 a night, $4,780 for 12 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 13, 2026 · 13 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $68 a night, $888 for 13 nights · 4★ The Westin St. Louis, $139 a night, $1,810.50 for 13 nights · 5★ Four Seasons Hotel St Louis, $396 a night, $5,146 for 13 nights
• Hotels in St. Louis for these nights (Nov 30 – Dec 14, 2026 · 14 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $69 a night, $962 for 14 nights · 4★ The Westin St. Louis, $137 a night, $1,916.50 for 14 nights · 5★ Four Seasons Hotel St Louis, $394 a night, $5,512 for 14 nights

All hotels in St. Louis

Route overview: Jacksonville to Saint Louis (STL) flight deals

2026-11-30 · one way · Axel-exclusive $227.50

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.

2026-11-30 · one way · Axel-exclusive $227.50

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.

2026-11-30 → 2026-12-01 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-01 20:00:00 → JAX 2026-12-01 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-30 → 2026-12-01 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-01 05:02:00 → JAX 2026-12-01 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-01 05:02:00 → ORD 2026-12-01 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-01 08:05:00 → JAX 2026-12-01 11:40:00.

2026-11-30 → 2026-12-02 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-02 20:00:00 → JAX 2026-12-02 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-30 → 2026-12-02 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-02 05:02:00 → JAX 2026-12-02 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-02 05:02:00 → ORD 2026-12-02 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-02 08:05:00 → JAX 2026-12-02 11:40:00.

2026-11-30 → 2026-12-03 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-03 18:15:00 → JAX 2026-12-03 21:15:00; nonstop; 120 minutes. Local airport times.

2026-11-30 → 2026-12-03 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-03 05:02:00 → JAX 2026-12-03 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-03 05:02:00 → ORD 2026-12-03 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-03 08:05:00 → JAX 2026-12-03 11:40:00.

2026-11-30 → 2026-12-04 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-04 20:00:00 → JAX 2026-12-04 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-30 → 2026-12-04 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-04 05:02:00 → JAX 2026-12-04 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-04 05:02:00 → ORD 2026-12-04 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-04 08:05:00 → JAX 2026-12-04 11:40:00.

2026-11-30 → 2026-12-06 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-06 20:00:00 → JAX 2026-12-06 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-30 → 2026-12-06 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-06 05:02:00 → JAX 2026-12-06 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-06 05:02:00 → ORD 2026-12-06 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-06 08:05:00 → JAX 2026-12-06 11:40:00.

2026-11-30 → 2026-12-07 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-07 19:55:00 → JAX 2026-12-07 22:55:00; nonstop; 120 minutes. Local airport times.

2026-11-30 → 2026-12-07 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-07 05:02:00 → JAX 2026-12-07 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-07 05:02:00 → ORD 2026-12-07 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-07 08:05:00 → JAX 2026-12-07 11:40:00.

2026-11-30 → 2026-12-08 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-08 20:00:00 → JAX 2026-12-08 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-30 → 2026-12-08 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-08 05:02:00 → JAX 2026-12-08 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-08 05:02:00 → ORD 2026-12-08 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-08 08:05:00 → JAX 2026-12-08 11:40:00.

2026-11-30 → 2026-12-10 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-10 18:15:00 → JAX 2026-12-10 21:15:00; nonstop; 120 minutes. Local airport times.

2026-11-30 → 2026-12-10 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-10 05:02:00 → JAX 2026-12-10 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-10 05:02:00 → ORD 2026-12-10 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-10 08:05:00 → JAX 2026-12-10 11:40:00.

2026-11-30 → 2026-12-11 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-11 20:00:00 → JAX 2026-12-11 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-30 → 2026-12-11 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-11 05:02:00 → JAX 2026-12-11 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-11 05:02:00 → ORD 2026-12-11 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-11 08:05:00 → JAX 2026-12-11 11:40:00.

2026-11-30 → 2026-12-12 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4697: STL 2026-12-12 10:05:00 → JAX 2026-12-12 13:00:00; nonstop; 115 minutes. Local airport times.

2026-11-30 → 2026-12-12 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-12 05:02:00 → JAX 2026-12-12 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-12 05:02:00 → ORD 2026-12-12 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-12 08:05:00 → JAX 2026-12-12 11:40:00.

2026-11-30 → 2026-12-14 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-30 05:45:00 → STL 2026-11-30 07:05:00; nonstop; 140 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-14 18:15:00 → JAX 2026-12-14 21:15:00; nonstop; 120 minutes. Local airport times.

2026-11-30 → 2026-12-14 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-30 06:20:00 → STL 2026-11-30 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-30 06:20:00 → CLT 2026-11-30 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-30 09:15:00 → STL 2026-11-30 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-14 05:02:00 → JAX 2026-12-14 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-14 05:02:00 → ORD 2026-12-14 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-14 08:05:00 → JAX 2026-12-14 11:40:00.

Explore this route

• All dates for this route
• Nov 29, 2026 · Return options
• Dec 1, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Jacksonville (JAX) to Saint Louis (STL) · Nov 30, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
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• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

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