Jacksonville (JAX) to Saint Louis (STL), Nov 26, 2026: round trips from $385, one way from $228

Jacksonville (JAX) to Saint Louis (STL), Nov 26, 2026: round trips from $385, one way from $228 on Axel, checked Nov 11, 2026. Lowest published fares: $385 round trip, Axel-exclusive, Southwest Airlines, nonstop, Nov 26, 2026 – Dec 1, 2026; $228 one way, Axel-exclusive, Southwest Airlines, nonstop, Nov 26, 2026; 1 adult, economy, checked Nov 11, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, labelled with the check date shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and check dates already shown here.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in St. Louis for these nights (Nov 26–27, 2026 · 1 night · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $60 a night · 4★ Hilton St. Louis at the Ballpark, $105 a night · 5★ Four Seasons Hotel St Louis, $369 a night
• Hotels in St. Louis for these nights (Nov 26–28, 2026 · 2 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $68 a night, $135 for 2 nights · 4★ Hilton St. Louis at the Ballpark, $104 a night, $207 for 2 nights · 5★ Four Seasons Hotel St Louis, $369 a night, $738 for 2 nights
• Hotels in St. Louis for these nights (Nov 26–29, 2026 · 3 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $66 a night, $199 for 3 nights · 4★ Hilton St. Louis at the Ballpark, $104 a night, $312 for 3 nights · 5★ Four Seasons Hotel St Louis, $368 a night, $1,105 for 3 nights
• Hotels in St. Louis for these nights (Nov 26–30, 2026 · 4 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $66 a night, $265 for 4 nights · 4★ Hilton St. Louis at the Ballpark, $104 a night, $417 for 4 nights · 5★ Four Seasons Hotel St Louis, $368 a night, $1,472 for 4 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 1, 2026 · 5 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $64 a night, $319 for 5 nights · 4★ Hilton St. Louis at the Ballpark, $104 a night, $521 for 5 nights · 5★ Four Seasons Hotel St Louis, $368 a night, $1,838 for 5 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 2, 2026 · 6 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $66 a night, $393 for 6 nights · 4★ Hilton St. Louis at the Ballpark, $104 a night, $626 for 6 nights · 5★ Four Seasons Hotel St Louis, $367 a night, $2,204 for 6 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 3, 2026 · 7 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $65 a night, $454 for 7 nights · 4★ Hilton St. Louis at the Ballpark, $104 a night, $731 for 7 nights · 5★ Four Seasons Hotel St Louis, $367 a night, $2,570 for 7 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 4, 2026 · 8 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $65 a night, $518 for 8 nights · 4★ Hilton St. Louis at the Ballpark, $105 a night, $836 for 8 nights · 5★ Four Seasons Hotel St Louis, $390 a night, $3,120 for 8 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 5, 2026 · 9 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $66 a night, $591 for 9 nights · 4★ The Westin St. Louis, $133 a night, $1,198.50 for 9 nights · 5★ Four Seasons Hotel St Louis, $402 a night, $3,622 for 9 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 6, 2026 · 10 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $67 a night, $666 for 10 nights · 4★ Angad Arts Hotel St. Louis, Tapestry Collection by Hilton, $141 a night, $1,414 for 10 nights · 5★ Four Seasons Hotel St Louis, $406 a night, $4,056 for 10 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 7, 2026 · 11 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $66 a night, $728 for 11 nights · 4★ The Westin St. Louis, $140 a night, $1,536.50 for 11 nights · 5★ Four Seasons Hotel St Louis, $402 a night, $4,422 for 11 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 8, 2026 · 12 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $67 a night, $802 for 12 nights · 4★ The Westin St. Louis, $138 a night, $1,659.50 for 12 nights · 5★ Four Seasons Hotel St Louis, $399 a night, $4,788 for 12 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 9, 2026 · 13 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $67 a night, $866 for 13 nights · 4★ The Westin St. Louis, $138 a night, $1,788.50 for 13 nights · 5★ Four Seasons Hotel St Louis, $396 a night, $5,154 for 13 nights
• Hotels in St. Louis for these nights (Nov 26 – Dec 10, 2026 · 14 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $67 a night, $940 for 14 nights · 4★ The Westin St. Louis, $137 a night, $1,912.50 for 14 nights · 5★ Four Seasons Hotel St Louis, $394 a night, $5,520 for 14 nights

All hotels in St. Louis

Route overview: Jacksonville to Saint Louis (STL) flight deals

2026-11-26 · one way · Axel-exclusive $227.50

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.

2026-11-26 · one way · Axel-exclusive $227.50

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.

2026-11-26 → 2026-11-27 · Axel-exclusive $435.50

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-11-27 20:00:00 → JAX 2026-11-27 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-26 → 2026-11-27 · Axel-exclusive $442.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-11-27 05:02:00 → JAX 2026-11-27 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-11-27 05:02:00 → ORD 2026-11-27 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-11-27 08:05:00 → JAX 2026-11-27 11:40:00.

2026-11-26 → 2026-11-28 · Axel-exclusive $435.50

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-11-28 19:55:00 → JAX 2026-11-28 22:55:00; nonstop; 120 minutes. Local airport times.

2026-11-26 → 2026-11-28 · Axel-exclusive $442.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-11-28 05:02:00 → JAX 2026-11-28 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-11-28 05:02:00 → ORD 2026-11-28 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-11-28 08:05:00 → JAX 2026-11-28 11:40:00.

2026-11-26 → 2026-11-29 · Axel-exclusive $435.50

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-11-29 19:55:00 → JAX 2026-11-29 22:55:00; nonstop; 120 minutes. Local airport times.

2026-11-26 → 2026-11-29 · Axel-exclusive $442.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-11-29 05:02:00 → JAX 2026-11-29 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-11-29 05:02:00 → ORD 2026-11-29 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-11-29 08:05:00 → JAX 2026-11-29 11:40:00.

2026-11-26 → 2026-11-30 · Axel-exclusive $435.50

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-11-30 19:55:00 → JAX 2026-11-30 22:55:00; nonstop; 120 minutes. Local airport times.

2026-11-26 → 2026-11-30 · Axel-exclusive $442.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-11-30 05:02:00 → JAX 2026-11-30 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-11-30 05:02:00 → ORD 2026-11-30 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-11-30 08:05:00 → JAX 2026-11-30 11:40:00.

2026-11-26 → 2026-12-02 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-02 20:00:00 → JAX 2026-12-02 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-26 → 2026-12-02 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-02 05:02:00 → JAX 2026-12-02 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-02 05:02:00 → ORD 2026-12-02 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-02 08:05:00 → JAX 2026-12-02 11:40:00.

2026-11-26 → 2026-12-03 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-03 18:15:00 → JAX 2026-12-03 21:15:00; nonstop; 120 minutes. Local airport times.

2026-11-26 → 2026-12-03 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-03 05:02:00 → JAX 2026-12-03 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-03 05:02:00 → ORD 2026-12-03 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-03 08:05:00 → JAX 2026-12-03 11:40:00.

2026-11-26 → 2026-12-04 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-04 20:00:00 → JAX 2026-12-04 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-26 → 2026-12-04 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-04 05:02:00 → JAX 2026-12-04 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-04 05:02:00 → ORD 2026-12-04 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-04 08:05:00 → JAX 2026-12-04 11:40:00.

2026-11-26 → 2026-12-06 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-06 20:00:00 → JAX 2026-12-06 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-26 → 2026-12-06 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-06 05:02:00 → JAX 2026-12-06 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-06 05:02:00 → ORD 2026-12-06 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-06 08:05:00 → JAX 2026-12-06 11:40:00.

2026-11-26 → 2026-12-07 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-07 19:55:00 → JAX 2026-12-07 22:55:00; nonstop; 120 minutes. Local airport times.

2026-11-26 → 2026-12-07 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-07 05:02:00 → JAX 2026-12-07 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-07 05:02:00 → ORD 2026-12-07 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-07 08:05:00 → JAX 2026-12-07 11:40:00.

2026-11-26 → 2026-12-08 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-08 20:00:00 → JAX 2026-12-08 23:05:00; nonstop; 125 minutes. Local airport times.

2026-11-26 → 2026-12-08 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-08 05:02:00 → JAX 2026-12-08 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-08 05:02:00 → ORD 2026-12-08 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-08 08:05:00 → JAX 2026-12-08 11:40:00.

2026-11-26 → 2026-12-10 · Axel-exclusive $385.25

• Southwest Airlines WN2265: JAX 2026-11-26 06:05:00 → STL 2026-11-26 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-10 18:15:00 → JAX 2026-12-10 21:15:00; nonstop; 120 minutes. Local airport times.

2026-11-26 → 2026-12-10 · Axel-exclusive $391.00

• American Airlines AA1576 / AA2486: JAX 2026-11-26 06:20:00 → STL 2026-11-26 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-11-26 06:20:00 → CLT 2026-11-26 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-11-26 09:15:00 → STL 2026-11-26 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-10 05:02:00 → JAX 2026-12-10 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-10 05:02:00 → ORD 2026-12-10 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-10 08:05:00 → JAX 2026-12-10 11:40:00.

Explore this route

• All dates for this route
• Nov 25, 2026 · Return options
• Nov 27, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Jacksonville (JAX) to Saint Louis (STL) · Nov 26, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with its displayed check date. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the nightly rate and the stay's total, from the lowest saved total among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and its displayed check date); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
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