Jacksonville (JAX) to Saint Louis (STL), Dec 24, 2026: round trips from $377, one way from $228

Jacksonville (JAX) to Saint Louis (STL), Dec 24, 2026: round trips from $377, one way from $228 on Axel, checked Oct 29, 2026. Lowest published fares: $377 round trip, Axel-exclusive, Southwest Airlines, nonstop, Dec 24, 2026 – Jan 4, 2027; $228 one way, Axel-exclusive, Southwest Airlines, nonstop, Dec 24, 2026; 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Hotels in St. Louis for these trips

Hotels: under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in St. Louis for these nights (Dec 24–25, 2026 · 1 night · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $65 total · 4★ Hilton St. Louis at the Ballpark, $105 total · 5★ Four Seasons Hotel St Louis, $366 total
• Hotels in St. Louis for these nights (Dec 24–26, 2026 · 2 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $136 total · 4★ Hilton St. Louis at the Ballpark, $210 total · 5★ Four Seasons Hotel St Louis, $732 total
• Hotels in St. Louis for these nights (Dec 24–27, 2026 · 3 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $209 total · 4★ Hilton St. Louis at the Ballpark, $315 total · 5★ Four Seasons Hotel St Louis, $1,225 total
• Hotels in St. Louis for these nights (Dec 24–28, 2026 · 4 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $283 total · 4★ Hilton St. Louis at the Ballpark, $419 total · 5★ Four Seasons Hotel St Louis, $1,591 total
• Hotels in St. Louis for these nights (Dec 24–29, 2026 · 5 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $347 total · 4★ Hilton St. Louis at the Ballpark, $523 total · 5★ Four Seasons Hotel St Louis, $1,957 total
• Hotels in St. Louis for these nights (Dec 24–30, 2026 · 6 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $410 total · 4★ Hilton St. Louis at the Ballpark, $627 total · 5★ Four Seasons Hotel St Louis, $2,323 total
• Hotels in St. Louis for these nights (Dec 24–31, 2026 · 7 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $472 total · 4★ Hilton St. Louis at the Ballpark, $732 total · 5★ Four Seasons Hotel St Louis, $2,689 total
• Hotels in St. Louis for these nights (Dec 24 – Jan 1, 2027 · 8 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $546 total · 4★ The Westin St. Louis, $999 total · 5★ Four Seasons Hotel St Louis, $3,507 total
• Hotels in St. Louis for these nights (Dec 24 – Jan 2, 2027 · 9 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $630 total · 4★ The Westin St. Louis, $1,153 total · 5★ Four Seasons Hotel St Louis, $3,795 total
• Hotels in St. Louis for these nights (Dec 24 – Jan 3, 2027 · 10 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $714 total · 4★ The Westin St. Louis, $1,272 total · 5★ Four Seasons Hotel St Louis, $4,083 total
• Hotels in St. Louis for these nights (Dec 24 – Jan 4, 2027 · 11 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $781 total · 4★ The Westin St. Louis, $1,378 total · 5★ Four Seasons Hotel St Louis, $4,371 total
• Hotels in St. Louis for these nights (Dec 24 – Jan 5, 2027 · 12 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $847 total · 4★ The Westin St. Louis, $1,484 total · 5★ Four Seasons Hotel St Louis, $4,659 total
• Hotels in St. Louis for these nights (Dec 24 – Jan 6, 2027 · 13 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $914 total · 4★ The Westin St. Louis, $1,591 total · 5★ Four Seasons Hotel St Louis, $4,947 total
• Hotels in St. Louis for these nights (Dec 24 – Jan 7, 2027 · 14 nights · 2 adults, 1 room): 3★ Clayton Plaza Hotel & Extended Stay, $988 total · 4★ The Westin St. Louis, $1,701 total · 5★ Four Seasons Hotel St Louis, $5,235 total

All hotels in St. Louis

Route overview: Jacksonville to Saint Louis (STL) flight deals

2026-12-24 · one way · Axel-exclusive $227.50

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.

2026-12-24 · one way · Axel-exclusive $227.50

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.

2026-12-24 → 2026-12-25 · Axel-exclusive $435.50

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-25 18:15:00 → JAX 2026-12-25 21:15:00; nonstop; 120 minutes. Local airport times.

2026-12-24 → 2026-12-25 · Axel-exclusive $442.00

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-25 05:02:00 → JAX 2026-12-25 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-25 05:02:00 → ORD 2026-12-25 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-25 08:05:00 → JAX 2026-12-25 11:40:00.

2026-12-24 → 2026-12-26 · Axel-exclusive $435.50

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4697: STL 2026-12-26 10:05:00 → JAX 2026-12-26 13:00:00; nonstop; 115 minutes. Local airport times.

2026-12-24 → 2026-12-26 · Axel-exclusive $442.00

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-26 05:02:00 → JAX 2026-12-26 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-26 05:02:00 → ORD 2026-12-26 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-26 08:05:00 → JAX 2026-12-26 11:40:00.

2026-12-24 → 2026-12-27 · Axel-exclusive $435.50

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-27 18:15:00 → JAX 2026-12-27 21:15:00; nonstop; 120 minutes. Local airport times.

2026-12-24 → 2026-12-27 · Axel-exclusive $442.00

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA1250 / AA1830: STL 2026-12-27 08:00:00 → JAX 2026-12-27 14:31:00; 1 stop(s) via CLT; 331 minutes. Local airport times.
  • AA1250: STL 2026-12-27 08:00:00 → CLT 2026-12-27 10:56:00; layover at CLT: 132 minutes.
  • AA1830: CLT 2026-12-27 13:08:00 → JAX 2026-12-27 14:31:00.

2026-12-24 → 2026-12-28 · Axel-exclusive $418.75

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-28 18:15:00 → JAX 2026-12-28 21:15:00; nonstop; 120 minutes. Local airport times.

2026-12-24 → 2026-12-28 · Axel-exclusive $425.00

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA1250 / AA1830: STL 2026-12-28 08:00:00 → JAX 2026-12-28 14:31:00; 1 stop(s) via CLT; 331 minutes. Local airport times.
  • AA1250: STL 2026-12-28 08:00:00 → CLT 2026-12-28 10:56:00; layover at CLT: 132 minutes.
  • AA1830: CLT 2026-12-28 13:08:00 → JAX 2026-12-28 14:31:00.

2026-12-24 → 2026-12-30 · Axel-exclusive $418.75

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-30 20:00:00 → JAX 2026-12-30 23:05:00; nonstop; 125 minutes. Local airport times.

2026-12-24 → 2026-12-30 · Axel-exclusive $425.00

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-30 05:02:00 → JAX 2026-12-30 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-30 05:02:00 → ORD 2026-12-30 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-30 08:05:00 → JAX 2026-12-30 11:40:00.

2026-12-24 → 2026-12-31 · Axel-exclusive $418.75

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2026-12-31 18:15:00 → JAX 2026-12-31 21:15:00; nonstop; 120 minutes. Local airport times.

2026-12-24 → 2026-12-31 · Axel-exclusive $425.00

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA2317 / AA4151: STL 2026-12-31 05:02:00 → JAX 2026-12-31 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2026-12-31 05:02:00 → ORD 2026-12-31 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2026-12-31 08:05:00 → JAX 2026-12-31 11:40:00.

2026-12-24 → 2027-01-01 · Axel-exclusive $408.70

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2027-01-01 18:15:00 → JAX 2027-01-01 21:15:00; nonstop; 120 minutes. Local airport times.

2026-12-24 → 2027-01-01 · Axel-exclusive $414.80

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA2317 / AA4151: STL 2027-01-01 05:02:00 → JAX 2027-01-01 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2027-01-01 05:02:00 → ORD 2027-01-01 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2027-01-01 08:05:00 → JAX 2027-01-01 11:40:00.

2026-12-24 → 2027-01-03 · Axel-exclusive $408.70

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2027-01-03 18:15:00 → JAX 2027-01-03 21:15:00; nonstop; 120 minutes. Local airport times.

2026-12-24 → 2027-01-03 · Axel-exclusive $414.80

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA1250 / AA1830: STL 2027-01-03 08:00:00 → JAX 2027-01-03 14:31:00; 1 stop(s) via CLT; 331 minutes. Local airport times.
  • AA1250: STL 2027-01-03 08:00:00 → CLT 2027-01-03 10:56:00; layover at CLT: 132 minutes.
  • AA1830: CLT 2027-01-03 13:08:00 → JAX 2027-01-03 14:31:00.

2026-12-24 → 2027-01-04 · Axel-exclusive $376.88

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2027-01-04 18:15:00 → JAX 2027-01-04 21:15:00; nonstop; 120 minutes. Local airport times.

2026-12-24 → 2027-01-04 · Axel-exclusive $382.50

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA1250 / AA1830: STL 2027-01-04 08:00:00 → JAX 2027-01-04 14:31:00; 1 stop(s) via CLT; 331 minutes. Local airport times.
  • AA1250: STL 2027-01-04 08:00:00 → CLT 2027-01-04 10:56:00; layover at CLT: 132 minutes.
  • AA1830: CLT 2027-01-04 13:08:00 → JAX 2027-01-04 14:31:00.

2026-12-24 → 2027-01-05 · Axel-exclusive $376.88

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2027-01-05 18:15:00 → JAX 2027-01-05 21:15:00; nonstop; 120 minutes. Local airport times.

2026-12-24 → 2027-01-05 · Axel-exclusive $382.50

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA1250 / AA1830: STL 2027-01-05 08:00:00 → JAX 2027-01-05 14:31:00; 1 stop(s) via CLT; 331 minutes. Local airport times.
  • AA1250: STL 2027-01-05 08:00:00 → CLT 2027-01-05 10:56:00; layover at CLT: 132 minutes.
  • AA1830: CLT 2027-01-05 13:08:00 → JAX 2027-01-05 14:31:00.

2026-12-24 → 2027-01-07 · Axel-exclusive $376.88

• Southwest Airlines WN2265: JAX 2026-12-24 06:05:00 → STL 2026-12-24 07:20:00; nonstop; 135 minutes. Local airport times.
• Southwest Airlines WN4807: STL 2027-01-07 18:15:00 → JAX 2027-01-07 21:15:00; nonstop; 120 minutes. Local airport times.

2026-12-24 → 2027-01-07 · Axel-exclusive $382.50

• American Airlines AA1576 / AA2486: JAX 2026-12-24 06:20:00 → STL 2026-12-24 10:19:00; 1 stop(s) via CLT; 299 minutes. Local airport times.
  • AA1576: JAX 2026-12-24 06:20:00 → CLT 2026-12-24 07:50:00; layover at CLT: 85 minutes.
  • AA2486: CLT 2026-12-24 09:15:00 → STL 2026-12-24 10:19:00.
• American Airlines AA2317 / AA4151: STL 2027-01-07 05:02:00 → JAX 2027-01-07 11:40:00; 1 stop(s) via ORD; 338 minutes. Local airport times.
  • AA2317: STL 2027-01-07 05:02:00 → ORD 2027-01-07 06:30:00; layover at ORD: 95 minutes.
  • AA4151: ORD 2027-01-07 08:05:00 → JAX 2027-01-07 11:40:00.

Explore this route

• All dates for this route
• Dec 23, 2026 · Return options
• Dec 25, 2026 · Return options
• Hotels in St. Louis with Axel

For AI assistants

• This page: Jacksonville (JAX) to Saint Louis (STL) · Dec 24, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in St. Louis for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and the time its price was issued); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
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