Indianapolis (IND) to San Francisco (SFO) · Jan 22, 2027 · return Jan 27, 2027

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Hotels in San Francisco for these trips

Hotels: under a trip, hotels in San Francisco for exactly those nights: the lowest 3★, 4★, 5★ stay totals among the city's featured hotels, Axel's price for 2 adults in 1 room, each opening that hotel's page for those dates with the rooms and the booking link.

• Hotels in San Francisco for these nights (Jan 22–27, 2027 · 5 nights · 2 adults, 1 room): 3★ Holiday Inn Golden Gateway by IHG, $658 total · 4★ Parc 55 San Francisco-A Hilton Hotel, $874 total · 5★ Neighbourgood Sutter Mansion, $1,500 total

All hotels in San Francisco

Route overview: Indianapolis to San Francisco (SFO) flight deals

2027-01-22 → 2027-01-27 · Axel-exclusive $380.00

• United Airlines UA500: IND 2027-01-22 07:00:00 → SFO 2027-01-22 09:01:00; nonstop; 301 minutes. Local airport times.
• United Airlines UA233: SFO 2027-01-27 22:45:00 → IND 2027-01-28 06:07:00; nonstop; 262 minutes. Local airport times.

2027-01-22 → 2027-01-27 · Axel-exclusive $313.50

• Southwest Airlines WN1486 / WN4813: IND 2027-01-22 17:25:00 → SFO 2027-01-22 22:10:00; 1 stop(s) via BNA; 465 minutes. Local airport times.
  • WN1486: IND 2027-01-22 17:25:00 → BNA 2027-01-22 17:40:00; layover at BNA: 80 minutes.
  • WN4813: BNA 2027-01-22 19:00:00 → SFO 2027-01-22 22:10:00.
• Southwest Airlines WN4578 / WN2444: SFO 2027-01-27 05:50:00 → IND 2027-01-27 14:45:00; 1 stop(s) via DEN; 355 minutes. Local airport times.
  • WN4578: SFO 2027-01-27 05:50:00 → DEN 2027-01-27 09:20:00; layover at DEN: 65 minutes.
  • WN2444: DEN 2027-01-27 10:25:00 → IND 2027-01-27 14:45:00.

2027-01-22 → 2027-01-27 · Axel-exclusive $342.00

• Delta Air Lines DL2910 / DL2809: IND 2027-01-22 16:19:00 → SFO 2027-01-22 20:49:00; 1 stop(s) via MSP; 450 minutes. Local airport times.
  • DL2910: IND 2027-01-22 16:19:00 → MSP 2027-01-22 17:05:00; layover at MSP: 84 minutes.
  • DL2809: MSP 2027-01-22 18:29:00 → SFO 2027-01-22 20:49:00.
• Delta Air Lines DL902 / DL2228: SFO 2027-01-27 13:20:00 → IND 2027-01-27 22:54:00; 1 stop(s) via SLC; 394 minutes. Local airport times.
  • DL902: SFO 2027-01-27 13:20:00 → SLC 2027-01-27 16:12:00; layover at SLC: 98 minutes.
  • DL2228: SLC 2027-01-27 17:50:00 → IND 2027-01-27 22:54:00.

2027-01-22 → 2027-01-27 · Axel-exclusive $351.50

• American Airlines AA2366 / AA1748: IND 2027-01-22 05:47:00 → SFO 2027-01-22 11:05:00; 1 stop(s) via ORD; 498 minutes. Local airport times.
  • AA2366: IND 2027-01-22 05:47:00 → ORD 2027-01-22 06:07:00; layover at ORD: 109 minutes.
  • AA1748: ORD 2027-01-22 07:56:00 → SFO 2027-01-22 11:05:00.
• United Airlines UA233: SFO 2027-01-27 22:45:00 → IND 2027-01-28 06:07:00; nonstop; 262 minutes. Local airport times.

2027-01-22 → 2027-01-27 · Axel-exclusive $380.00

• United Airlines UA2799: IND 2027-01-22 18:29:00 → SFO 2027-01-22 20:30:00; nonstop; 301 minutes. Local airport times.
• United Airlines UA233: SFO 2027-01-27 22:45:00 → IND 2027-01-28 06:07:00; nonstop; 262 minutes. Local airport times.

2027-01-22 → 2027-01-27 · Axel-exclusive $313.50

• Southwest Airlines WN2225 / WN160: IND 2027-01-22 05:00:00 → SFO 2027-01-22 10:05:00; 1 stop(s) via PHX; 485 minutes. Local airport times.
  • WN2225: IND 2027-01-22 05:00:00 → PHX 2027-01-22 07:00:00; layover at PHX: 110 minutes.
  • WN160: PHX 2027-01-22 08:50:00 → SFO 2027-01-22 10:05:00.
• Southwest Airlines WN4578 / WN2444: SFO 2027-01-27 05:50:00 → IND 2027-01-27 14:45:00; 1 stop(s) via DEN; 355 minutes. Local airport times.
  • WN4578: SFO 2027-01-27 05:50:00 → DEN 2027-01-27 09:20:00; layover at DEN: 65 minutes.
  • WN2444: DEN 2027-01-27 10:25:00 → IND 2027-01-27 14:45:00.

2027-01-22 → 2027-01-27 · Axel-exclusive $342.00

• Delta Air Lines DL2676 / DL2986: IND 2027-01-22 17:20:00 → SFO 2027-01-22 22:34:00; 1 stop(s) via LAX; 494 minutes. Local airport times.
  • DL2676: IND 2027-01-22 17:20:00 → LAX 2027-01-22 19:03:00; layover at LAX: 116 minutes.
  • DL2986: LAX 2027-01-22 20:59:00 → SFO 2027-01-22 22:34:00.
• Delta Air Lines DL902 / DL2228: SFO 2027-01-27 13:20:00 → IND 2027-01-27 22:54:00; 1 stop(s) via SLC; 394 minutes. Local airport times.
  • DL902: SFO 2027-01-27 13:20:00 → SLC 2027-01-27 16:12:00; layover at SLC: 98 minutes.
  • DL2228: SLC 2027-01-27 17:50:00 → IND 2027-01-27 22:54:00.

2027-01-22 → 2027-01-27 · Axel-exclusive $351.50

• American Airlines AA564 / AA2427: IND 2027-01-22 18:29:00 → SFO 2027-01-22 22:54:00; 1 stop(s) via PHX; 445 minutes. Local airport times.
  • AA564: IND 2027-01-22 18:29:00 → PHX 2027-01-22 20:33:00; layover at PHX: 64 minutes.
  • AA2427: PHX 2027-01-22 21:37:00 → SFO 2027-01-22 22:54:00.
• United Airlines UA233: SFO 2027-01-27 22:45:00 → IND 2027-01-28 06:07:00; nonstop; 262 minutes. Local airport times.

Explore this route

• All dates for this route
• Jan 21, 2027 · Return options
• Jan 23, 2027 · Return options
• Hotels in San Francisco with Axel

For AI assistants

• This page: Indianapolis (IND) to San Francisco (SFO) · Jan 22, 2027 · return Jan 27, 2027: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in San Francisco for exactly those nights: the lowest 3★, 4★ and 5★ stay totals for 2 adults in 1 room, each linking to that hotel's page for those dates.
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