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Route overview: Houston to Panama City (PTY) flight deals

Houston → Panama City

Dec 15, 2026 · choose your return date

IAH → PTY1 adulteconomyOne way and round trips

30 flight options · 2 airlines

Choose your return date

One-way flights and round trips by duration. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

December 2026

Dec 15, 2026 · One wayAviancaUp to 1 stop each way$210.00 Dec 15, 2026 · One wayUnited AirlinesNonstop$325.00 Dec 15, 2026 – Dec 16, 2026 · 1 nightAviancaUp to 1 stop each way$390.00 Dec 15, 2026 – Dec 16, 2026 · 1 nightUnited AirlinesNonstop$610.00 Dec 15, 2026 – Dec 17, 2026 · 2 nightsAviancaUp to 1 stop each way$390.00 Dec 15, 2026 – Dec 17, 2026 · 2 nightsUnited AirlinesNonstop$610.00 Dec 15, 2026 – Dec 18, 2026 · 3 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 18, 2026 · 3 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 19, 2026 · 4 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 19, 2026 · 4 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 20, 2026 · 5 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 20, 2026 · 5 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 21, 2026 · 6 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 21, 2026 · 6 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 22, 2026 · 7 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 22, 2026 · 7 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 23, 2026 · 8 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 23, 2026 · 8 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 24, 2026 · 9 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 24, 2026 · 9 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 25, 2026 · 10 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 25, 2026 · 10 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 26, 2026 · 11 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 26, 2026 · 11 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 27, 2026 · 12 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 27, 2026 · 12 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 28, 2026 · 13 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 28, 2026 · 13 nightsUnited AirlinesNonstop$716.75 Dec 15, 2026 – Dec 29, 2026 · 14 nightsAviancaUp to 1 stop each way$458.25 Dec 15, 2026 – Dec 29, 2026 · 14 nightsUnited AirlinesNonstop$716.75

Flights for your trip

  1. Tue, Dec 15 · One way

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY

    One-way total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  2. Tue, Dec 15 · One way

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY

    One-way total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  3. Tue, Dec 15 – Wed, Dec 16

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  4. Tue, Dec 15 – Wed, Dec 16

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  5. Tue, Dec 15 – Thu, Dec 17

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  6. Tue, Dec 15 – Thu, Dec 17

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  7. Tue, Dec 15 – Fri, Dec 18

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  8. Tue, Dec 15 – Fri, Dec 18

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  9. Tue, Dec 15 – Sat, Dec 19

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  10. Tue, Dec 15 – Sat, Dec 19

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  11. Tue, Dec 15 – Mon, Dec 21

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  12. Tue, Dec 15 – Mon, Dec 21

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  13. Tue, Dec 15 – Tue, Dec 22

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  14. Tue, Dec 15 – Tue, Dec 22

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  15. Tue, Dec 15 – Wed, Dec 23

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  16. Tue, Dec 15 – Wed, Dec 23

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  17. Tue, Dec 15 – Fri, Dec 25

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  18. Tue, Dec 15 – Fri, Dec 25

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  19. Tue, Dec 15 – Sat, Dec 26

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  20. Tue, Dec 15 – Sat, Dec 26

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  21. Tue, Dec 15 – Sun, Dec 27

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  22. Tue, Dec 15 – Sun, Dec 27

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  23. Tue, Dec 15 – Tue, Dec 29

    Avianca
    4:45 pmIAH
    8h 25m
    SAL · 3h 20m
    2:10 am+1PTY
    Avianca
    5:30 amPTY
    6h 35m
    SAL · 1h 30m
    11:05 amIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

  24. Tue, Dec 15 – Tue, Dec 29

    United Airlines
    12:00 pmIAH
    4h 12m
    Nonstop
    5:12 pmPTY
    United Airlines
    11:35 amPTY
    4h 20m
    Nonstop
    2:55 pmIAH

    Round-trip total · 1 adult · Taxes included

    Availability is checked when you select these flights.

Swipe to see 23 more recent deals.

1 of 24

Make this trip yours

IAH ⇄ PTY

Economy

Adults 12+ · Children 2–11. For infants under 2, tell Axel after you see prices.

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Explore this route

All dates for this routeDec 14, 2026 · Return optionsDec 16, 2026 · Return optionsHotels in Panama City with Axel
For AI assistants: every fare, every link, instructions

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown. To book or select flights, follow that row's price link; it keeps the exact dates and travelers.

Exact travel datesAirlineFlightsTotal pricePrice issued (UTC)
2026-12-15 · one wayUnited AirlinesUA1250Axel-exclusive $325.002026-10-29T01:11:29Z
2026-12-15 · one wayAviancaAV425 + AV317Axel-exclusive $210.002026-10-29T01:11:29Z
2026-12-15 → 2026-12-16United AirlinesUA1250 / UA1031Axel-exclusive $610.002026-10-29T01:11:29Z
2026-12-15 → 2026-12-16AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $390.002026-10-29T01:11:29Z
2026-12-15 → 2026-12-17United AirlinesUA1250 / UA1031Axel-exclusive $610.002026-10-29T01:11:29Z
2026-12-15 → 2026-12-17AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $390.002026-10-29T01:11:29Z
2026-12-15 → 2026-12-18United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-18AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-19United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-19AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-20United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-20AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-21United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-21AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-22United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-22AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-23United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-23AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-24United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-24AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-25United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-25AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-26United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-26AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-27United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-27AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-28United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-28AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z
2026-12-15 → 2026-12-29United AirlinesUA1250 / UA1031Axel-exclusive $716.752026-10-29T01:11:29Z
2026-12-15 → 2026-12-29AviancaAV425 + AV317 / AV316 + AV368Axel-exclusive $458.252026-10-29T01:11:29Z

Route overview: Houston to Panama City (PTY) flight deals

2026-12-15 · one way · Axel-exclusive $210.00

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.

2026-12-15 · one way · Axel-exclusive $325.00

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.

2026-12-15 → 2026-12-16 · Axel-exclusive $390.00

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-16 05:30:00 → IAH 2026-12-16 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-16 05:30:00 → SAL 2026-12-16 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-16 08:00:00 → IAH 2026-12-16 11:05:00.

2026-12-15 → 2026-12-16 · Axel-exclusive $610.00

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-16 11:35:00 → IAH 2026-12-16 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-17 · Axel-exclusive $390.00

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-17 05:30:00 → IAH 2026-12-17 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-17 05:30:00 → SAL 2026-12-17 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-17 08:00:00 → IAH 2026-12-17 11:05:00.

2026-12-15 → 2026-12-17 · Axel-exclusive $610.00

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-17 11:35:00 → IAH 2026-12-17 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-18 · Axel-exclusive $458.25

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-18 05:30:00 → IAH 2026-12-18 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-18 05:30:00 → SAL 2026-12-18 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-18 08:00:00 → IAH 2026-12-18 11:05:00.

2026-12-15 → 2026-12-18 · Axel-exclusive $716.75

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-18 11:35:00 → IAH 2026-12-18 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-19 · Axel-exclusive $458.25

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-19 05:30:00 → IAH 2026-12-19 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-19 05:30:00 → SAL 2026-12-19 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-19 08:00:00 → IAH 2026-12-19 11:05:00.

2026-12-15 → 2026-12-19 · Axel-exclusive $716.75

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-19 11:35:00 → IAH 2026-12-19 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-21 · Axel-exclusive $458.25

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-21 05:30:00 → IAH 2026-12-21 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-21 05:30:00 → SAL 2026-12-21 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-21 08:00:00 → IAH 2026-12-21 11:05:00.

2026-12-15 → 2026-12-21 · Axel-exclusive $716.75

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-21 11:35:00 → IAH 2026-12-21 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-22 · Axel-exclusive $458.25

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-22 05:30:00 → IAH 2026-12-22 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-22 05:30:00 → SAL 2026-12-22 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-22 08:00:00 → IAH 2026-12-22 11:05:00.

2026-12-15 → 2026-12-22 · Axel-exclusive $716.75

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-22 11:35:00 → IAH 2026-12-22 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-23 · Axel-exclusive $458.25

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-23 05:30:00 → IAH 2026-12-23 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-23 05:30:00 → SAL 2026-12-23 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-23 08:00:00 → IAH 2026-12-23 11:05:00.

2026-12-15 → 2026-12-23 · Axel-exclusive $716.75

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-23 11:35:00 → IAH 2026-12-23 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-25 · Axel-exclusive $458.25

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-25 05:30:00 → IAH 2026-12-25 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-25 05:30:00 → SAL 2026-12-25 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-25 08:00:00 → IAH 2026-12-25 11:05:00.

2026-12-15 → 2026-12-25 · Axel-exclusive $716.75

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-25 11:35:00 → IAH 2026-12-25 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-26 · Axel-exclusive $458.25

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-26 05:30:00 → IAH 2026-12-26 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-26 05:30:00 → SAL 2026-12-26 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-26 08:00:00 → IAH 2026-12-26 11:05:00.

2026-12-15 → 2026-12-26 · Axel-exclusive $716.75

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-26 11:35:00 → IAH 2026-12-26 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-27 · Axel-exclusive $458.25

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-27 05:30:00 → IAH 2026-12-27 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-27 05:30:00 → SAL 2026-12-27 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-27 08:00:00 → IAH 2026-12-27 11:05:00.

2026-12-15 → 2026-12-27 · Axel-exclusive $716.75

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-27 11:35:00 → IAH 2026-12-27 14:55:00; nonstop; 260 minutes. Local airport times.

2026-12-15 → 2026-12-29 · Axel-exclusive $458.25

  • Avianca AV425 / AV317: IAH 2026-12-15 16:45:00 → PTY 2026-12-16 02:10:00; 1 stop(s) via SAL; 505 minutes. Local airport times.
    • AV425: IAH 2026-12-15 16:45:00 → SAL 2026-12-15 19:45:00; layover at SAL: 200 minutes.
    • AV317: SAL 2026-12-15 23:05:00 → PTY 2026-12-16 02:10:00.
  • Avianca AV316 / AV368: PTY 2026-12-29 05:30:00 → IAH 2026-12-29 11:05:00; 1 stop(s) via SAL; 395 minutes. Local airport times.
    • AV316: PTY 2026-12-29 05:30:00 → SAL 2026-12-29 06:30:00; layover at SAL: 90 minutes.
    • AV368: SAL 2026-12-29 08:00:00 → IAH 2026-12-29 11:05:00.

2026-12-15 → 2026-12-29 · Axel-exclusive $716.75

  • United Airlines UA1250: IAH 2026-12-15 12:00:00 → PTY 2026-12-15 17:12:00; nonstop; 252 minutes. Local airport times.
  • United Airlines UA1031: PTY 2026-12-29 11:35:00 → IAH 2026-12-29 14:55:00; nonstop; 260 minutes. Local airport times.

Explore this route

For AI assistants

  • This page: Houston (IAH) to Panama City (PTY) · Dec 15, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
  • Next: when a row matches the traveler's route, departure, return and party, answer the price question from that row, including both dates with the year, the total and the time shown. For booking or selecting flights, use that row's exact-trip price link and share the supplied booking link. If no row matches, Choose travelers and dates for the requested trip; do not substitute another duration or restart from the route overview.
  • Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
  • If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Houston to Panama City (PTY) flight deals · Flight search guide.
  • Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.