Houston (IAH) to Medellin (MDE), Dec 25–27, 2026: from $338 one way

Houston (IAH) to Medellin (MDE), Dec 25–27, 2026: from $338 one way on Axel, checked Oct 29, 2026. Lowest published fare: $338 one way, Axel-exclusive, JetBlue Airways, 1 stop, Dec 25, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Houston to Medellin (MDE) flight deals

2026-12-26 · one way · Axel-exclusive $445.50

• United Airlines UA2741: IAH 2026-12-26 23:53:00 → MDE 2026-12-27 05:35:00; nonstop; 282 minutes. Local airport times.

2026-12-26 · one way · Axel-exclusive $337.50

• JetBlue Airways B62380 / B641: IAH 2026-12-26 07:00:00 → MDE 2026-12-26 15:55:00; 1 stop(s) via FLL; 475 minutes. Local airport times.
  • B62380: IAH 2026-12-26 07:00:00 → FLL 2026-12-26 10:38:00; layover at FLL: 104 minutes.
  • B641: FLL 2026-12-26 12:22:00 → MDE 2026-12-26 15:55:00.

2026-12-27 · one way · Axel-exclusive $384.75

• American Airlines AA665 / AA1129: IAH 2026-12-27 12:48:00 → MDE 2026-12-27 21:17:00; 1 stop(s) via MIA; 449 minutes. Local airport times.
  • AA665: IAH 2026-12-27 12:48:00 → MIA 2026-12-27 16:19:00; layover at MIA: 91 minutes.
  • AA1129: MIA 2026-12-27 17:50:00 → MDE 2026-12-27 21:17:00.

2026-12-25 · one way · Axel-exclusive $445.50

• United Airlines UA2741: IAH 2026-12-25 23:53:00 → MDE 2026-12-26 05:35:00; nonstop; 282 minutes. Local airport times.

2026-12-26 · one way · Axel-exclusive $445.50

• United Airlines UA1675: IAH 2026-12-26 16:25:00 → MDE 2026-12-26 22:10:00; nonstop; 285 minutes. Local airport times.

2026-12-25 · one way · Axel-exclusive $445.50

• United Airlines UA1675: IAH 2026-12-25 16:25:00 → MDE 2026-12-25 22:10:00; nonstop; 285 minutes. Local airport times.

2026-12-27 · one way · Axel-exclusive $445.50

• United Airlines UA1675: IAH 2026-12-27 16:25:00 → MDE 2026-12-27 22:10:00; nonstop; 285 minutes. Local airport times.

2026-12-27 · one way · Axel-exclusive $445.50

• United Airlines UA2741: IAH 2026-12-27 23:53:00 → MDE 2026-12-28 05:35:00; nonstop; 282 minutes. Local airport times.

2026-12-25 · one way · Axel-exclusive $337.50

• JetBlue Airways B62380 / B641: IAH 2026-12-25 07:00:00 → MDE 2026-12-25 15:55:00; 1 stop(s) via FLL; 475 minutes. Local airport times.
  • B62380: IAH 2026-12-25 07:00:00 → FLL 2026-12-25 10:38:00; layover at FLL: 104 minutes.
  • B641: FLL 2026-12-25 12:22:00 → MDE 2026-12-25 15:55:00.

2026-12-27 · one way · Axel-exclusive $337.50

• JetBlue Airways B62380 / B641: IAH 2026-12-27 07:00:00 → MDE 2026-12-27 15:55:00; 1 stop(s) via FLL; 475 minutes. Local airport times.
  • B62380: IAH 2026-12-27 07:00:00 → FLL 2026-12-27 10:38:00; layover at FLL: 104 minutes.
  • B641: FLL 2026-12-27 12:22:00 → MDE 2026-12-27 15:55:00.

2026-12-25 · one way · Axel-exclusive $384.75

• American Airlines AA665 / AA1129: IAH 2026-12-25 12:48:00 → MDE 2026-12-25 21:17:00; 1 stop(s) via MIA; 449 minutes. Local airport times.
  • AA665: IAH 2026-12-25 12:48:00 → MIA 2026-12-25 16:19:00; layover at MIA: 91 minutes.
  • AA1129: MIA 2026-12-25 17:50:00 → MDE 2026-12-25 21:17:00.

2026-12-26 · one way · Axel-exclusive $384.75

• American Airlines AA665 / AA1129: IAH 2026-12-26 12:48:00 → MDE 2026-12-26 21:17:00; 1 stop(s) via MIA; 449 minutes. Local airport times.
  • AA665: IAH 2026-12-26 12:48:00 → MIA 2026-12-26 16:19:00; layover at MIA: 91 minutes.
  • AA1129: MIA 2026-12-26 17:50:00 → MDE 2026-12-26 21:17:00.

2026-12-27 · one way · Axel-exclusive $391.50

• United Airlines UA209 / AV9302: IAH 2026-12-27 23:20:00 → MDE 2026-12-28 10:00:00; 1 stop(s) via BOG; 580 minutes. Local airport times.
  • UA209: IAH 2026-12-27 23:20:00 → BOG 2026-12-28 05:10:00; layover at BOG: 225 minutes.
  • AV9302: BOG 2026-12-28 08:55:00 → MDE 2026-12-28 10:00:00.

2026-12-25 · one way · Axel-exclusive $391.50

• United Airlines UA496 / AV203: IAH 2026-12-25 14:23:00 → MDE 2026-12-25 23:10:00; 1 stop(s) via MCO; 467 minutes. Local airport times.
  • UA496: IAH 2026-12-25 14:23:00 → MCO 2026-12-25 17:45:00; layover at MCO: 95 minutes.
  • AV203: MCO 2026-12-25 19:20:00 → MDE 2026-12-25 23:10:00.

2026-12-25 · one way · Axel-exclusive $391.50

• United Airlines UA1034 / CM155: IAH 2026-12-25 14:27:00 → MDE 2026-12-25 22:50:00; 1 stop(s) via PTY; 443 minutes. Local airport times.
  • UA1034: IAH 2026-12-25 14:27:00 → PTY 2026-12-25 19:38:00; layover at PTY: 106 minutes.
  • CM155: PTY 2026-12-25 21:24:00 → MDE 2026-12-25 22:50:00.

2026-12-27 · one way · Axel-exclusive $391.50

• United Airlines UA1034 / CM155: IAH 2026-12-27 14:27:00 → MDE 2026-12-27 22:50:00; 1 stop(s) via PTY; 443 minutes. Local airport times.
  • UA1034: IAH 2026-12-27 14:27:00 → PTY 2026-12-27 19:38:00; layover at PTY: 106 minutes.
  • CM155: PTY 2026-12-27 21:24:00 → MDE 2026-12-27 22:50:00.

2026-12-25 · one way · Axel-exclusive $391.50

• United Airlines UA1871 / AV33: IAH 2026-12-25 23:59:00 → MDE 2026-12-26 08:25:00; 1 stop(s) via MIA; 446 minutes. Local airport times.
  • UA1871: IAH 2026-12-25 23:59:00 → MIA 2026-12-26 03:30:00; layover at MIA: 95 minutes.
  • AV33: MIA 2026-12-26 05:05:00 → MDE 2026-12-26 08:25:00.

2026-12-26 · one way · Axel-exclusive $391.50

• United Airlines UA1034 / CM155: IAH 2026-12-26 14:27:00 → MDE 2026-12-26 22:50:00; 1 stop(s) via PTY; 443 minutes. Local airport times.
  • UA1034: IAH 2026-12-26 14:27:00 → PTY 2026-12-26 19:38:00; layover at PTY: 106 minutes.
  • CM155: PTY 2026-12-26 21:24:00 → MDE 2026-12-26 22:50:00.

2026-12-26 · one way · Axel-exclusive $391.50

• United Airlines UA496 / AV203: IAH 2026-12-26 14:23:00 → MDE 2026-12-26 23:10:00; 1 stop(s) via MCO; 467 minutes. Local airport times.
  • UA496: IAH 2026-12-26 14:23:00 → MCO 2026-12-26 17:45:00; layover at MCO: 95 minutes.
  • AV203: MCO 2026-12-26 19:20:00 → MDE 2026-12-26 23:10:00.

2026-12-27 · one way · Axel-exclusive $391.50

• United Airlines UA1871 / AV33: IAH 2026-12-27 23:59:00 → MDE 2026-12-28 08:25:00; 1 stop(s) via MIA; 446 minutes. Local airport times.
  • UA1871: IAH 2026-12-27 23:59:00 → MIA 2026-12-28 03:30:00; layover at MIA: 95 minutes.
  • AV33: MIA 2026-12-28 05:05:00 → MDE 2026-12-28 08:25:00.

2026-12-25 · one way · Axel-exclusive $391.50

• United Airlines UA209 / AV9302: IAH 2026-12-25 23:20:00 → MDE 2026-12-26 10:00:00; 1 stop(s) via BOG; 580 minutes. Local airport times.
  • UA209: IAH 2026-12-25 23:20:00 → BOG 2026-12-26 05:10:00; layover at BOG: 225 minutes.
  • AV9302: BOG 2026-12-26 08:55:00 → MDE 2026-12-26 10:00:00.

2026-12-26 · one way · Axel-exclusive $391.50

• United Airlines UA1871 / AV33: IAH 2026-12-26 23:59:00 → MDE 2026-12-27 08:25:00; 1 stop(s) via MIA; 446 minutes. Local airport times.
  • UA1871: IAH 2026-12-26 23:59:00 → MIA 2026-12-27 03:30:00; layover at MIA: 95 minutes.
  • AV33: MIA 2026-12-27 05:05:00 → MDE 2026-12-27 08:25:00.

2026-12-26 · one way · Axel-exclusive $391.50

• United Airlines UA209 / AV9302: IAH 2026-12-26 23:20:00 → MDE 2026-12-27 10:00:00; 1 stop(s) via BOG; 580 minutes. Local airport times.
  • UA209: IAH 2026-12-26 23:20:00 → BOG 2026-12-27 05:10:00; layover at BOG: 225 minutes.
  • AV9302: BOG 2026-12-27 08:55:00 → MDE 2026-12-27 10:00:00.

2026-12-27 · one way · Axel-exclusive $391.50

• United Airlines UA496 / AV203: IAH 2026-12-27 14:23:00 → MDE 2026-12-27 23:10:00; 1 stop(s) via MCO; 467 minutes. Local airport times.
  • UA496: IAH 2026-12-27 14:23:00 → MCO 2026-12-27 17:45:00; layover at MCO: 95 minutes.
  • AV203: MCO 2026-12-27 19:20:00 → MDE 2026-12-27 23:10:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

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