Greenville (GSP) to Chicago (ORD), Nov 24, 2026: from $208 one way

Greenville (GSP) to Chicago (ORD), Nov 24, 2026: from $208 one way on Axel, checked Oct 29, 2026. Lowest published fare: $208 one way, Axel-exclusive, American Airlines, 1 stop, Nov 24, 2026, 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Greenville, SC (GSP) to Chicago (ORD) flight deals

2026-11-24 · one way · Axel-exclusive $227.50

• American Airlines AA5144: GSP 2026-11-24 07:02:00 → ORD 2026-11-24 08:34:00; nonstop; 152 minutes. Local airport times.

2026-11-24 · one way · Axel-exclusive $234.00

• United Airlines UA5474: GSP 2026-11-24 06:20:00 → ORD 2026-11-24 07:36:00; nonstop; 136 minutes. Local airport times.

2026-11-24 · one way · Axel-exclusive $221.00

• Delta Air Lines DL1725 / DL2879: GSP 2026-11-24 14:07:00 → ORD 2026-11-24 19:05:00; 1 stop(s) via ATL; 358 minutes. Local airport times.
  • DL1725: GSP 2026-11-24 14:07:00 → ATL 2026-11-24 15:14:00; layover at ATL: 151 minutes.
  • DL2879: ATL 2026-11-24 17:45:00 → ORD 2026-11-24 19:05:00.

2026-11-24 · one way · Axel-exclusive $227.50

• American Airlines AA4242: GSP 2026-11-24 18:47:00 → ORD 2026-11-24 20:15:00; nonstop; 148 minutes. Local airport times.

2026-11-24 · one way · Axel-exclusive $234.00

• United Airlines UA5862: GSP 2026-11-24 14:04:00 → ORD 2026-11-24 15:15:00; nonstop; 131 minutes. Local airport times.

2026-11-24 · one way · Axel-exclusive $208.00

• American Airlines AA5083 / AA3183: GSP 2026-11-24 15:41:00 → ORD 2026-11-24 21:31:00; 1 stop(s) via DCA; 410 minutes. Local airport times.
  • AA5083: GSP 2026-11-24 15:41:00 → DCA 2026-11-24 17:27:00; layover at DCA: 159 minutes.
  • AA3183: DCA 2026-11-24 20:06:00 → ORD 2026-11-24 21:31:00.

2026-11-24 · one way · Axel-exclusive $208.00

• American Airlines AA6099 / AA3178: GSP 2026-11-24 13:37:00 → ORD 2026-11-24 17:45:00; 1 stop(s) via CLT; 308 minutes. Local airport times.
  • AA6099: GSP 2026-11-24 13:37:00 → CLT 2026-11-24 14:49:00; layover at CLT: 100 minutes.
  • AA3178: CLT 2026-11-24 16:29:00 → ORD 2026-11-24 17:45:00.

2026-11-24 · one way · Axel-exclusive $214.50

• United Airlines UA4521 / UA1786: GSP 2026-11-24 10:26:00 → ORD 2026-11-24 16:54:00; 1 stop(s) via IAD; 448 minutes. Local airport times.
  • UA4521: GSP 2026-11-24 10:26:00 → IAD 2026-11-24 11:55:00; layover at IAD: 215 minutes.
  • UA1786: IAD 2026-11-24 15:30:00 → ORD 2026-11-24 16:54:00.

2026-11-24 · one way · Axel-exclusive $221.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-11-24 07:21:00 → ORD 2026-11-24 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-11-24 07:21:00 → DTW 2026-11-24 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-11-24 10:20:00 → ORD 2026-11-24 10:59:00.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 23, 2026 · Return options
• Nov 25, 2026 · Return options
• Hotels in Chicago with Axel

For AI assistants

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