Greenville (GSP) to Chicago (ORD), Dec 26, 2026: round trips from $359, one way from $213

Greenville (GSP) to Chicago (ORD), Dec 26, 2026: round trips from $359, one way from $213 on Axel, checked Oct 29, 2026. Lowest published fares: $359 round trip, Axel-exclusive, American Airlines, 1 stop, Dec 26, 2026 – Jan 9, 2027; $213 one way, Axel-exclusive, Delta Air Lines, 1 stop, Dec 26, 2026; 1 adult, economy, checked Oct 29, 2026. Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

Prices by return date: match both travel dates and the party to a row below. Each total is for that exact trip, issued at the time shown.

Date links open published trip details for exploration. Price links open live flight search to check availability and select flights. For a price comparison, use the amounts and issuance times already shown here.

Hotels in Chicago for these trips

Hotels: under a trip, hotels in Chicago for exactly those nights link to the hotel pages for 2 adults in 1 room. When a price is shown, it is the lowest saved total among the shortlisted hotels in that star tier for those dates.

• Hotels in Chicago for these nights (Dec 26–27, 2026 · 1 night · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $93 total · 4★ Freehand Chicago, $84 total · 5★ Sofitel Chicago Magnificent Mile, $206 total
• Hotels in Chicago for these nights (Dec 26–28, 2026 · 2 nights · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $191 total · 4★ Freehand Chicago, $138 total · 5★ Sofitel Chicago Magnificent Mile, $416 total
• Hotels in Chicago for these nights (Dec 26–29, 2026 · 3 nights · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $295 total · 4★ Freehand Chicago, $210 total · 5★ Sofitel Chicago Magnificent Mile, $622 total
• Hotels in Chicago for these nights (Dec 26–30, 2026 · 4 nights · 2 adults, 1 room): 3★ Hotel Versey, $391 total · 4★ Freehand Chicago, $282 total · 5★ Sofitel Chicago Magnificent Mile, $829 total
• Hotels in Chicago for these nights (Dec 26–31, 2026 · 5 nights · 2 adults, 1 room): 3★ Hotel Versey, $498 total · 4★ Freehand Chicago, $364 total · 5★ Sofitel Chicago Magnificent Mile, $1,032 total
• Hotels in Chicago for these nights (Dec 26 – Jan 1, 2027 · 6 nights · 2 adults, 1 room): 3★ The Willows Hotel, $694 total · 4★ Freehand Chicago, $541 total · 5★ Sofitel Chicago Magnificent Mile, $1,482 total
• Hotels in Chicago for these nights (Dec 26 – Jan 2, 2027 · 7 nights · 2 adults, 1 room): 3★ The Willows Hotel, $834 total · 4★ Freehand Chicago, $619 total · 5★ Sofitel Chicago Magnificent Mile, $1,685 total
• Hotels in Chicago for these nights (Dec 26 – Jan 3, 2027 · 8 nights · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $935 total · 4★ Freehand Chicago, $697 total · 5★ Sofitel Chicago Magnificent Mile, $1,895 total
• Hotels in Chicago for these nights (Dec 26 – Jan 4, 2027 · 9 nights · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $1,010 total · 4★ Freehand Chicago, $768 total · 5★ Sofitel Chicago Magnificent Mile, $2,125 total
• Hotels in Chicago for these nights (Dec 26 – Jan 5, 2027 · 10 nights · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $1,085 total · 4★ Freehand Chicago, $839 total · 5★ Sofitel Chicago Magnificent Mile, $2,335 total
• Hotels in Chicago for these nights (Dec 26 – Jan 6, 2027 · 11 nights · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $1,160 total · 4★ Freehand Chicago, $911 total · 5★ Sofitel Chicago Magnificent Mile, $2,541 total
• Hotels in Chicago for these nights (Dec 26 – Jan 7, 2027 · 12 nights · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $1,243 total · 4★ Freehand Chicago, $984 total · 5★ Sofitel Chicago Magnificent Mile, $2,751 total
• Hotels in Chicago for these nights (Dec 26 – Jan 8, 2027 · 13 nights · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $1,318 total · 4★ Freehand Chicago, $1,054 total · 5★ Sofitel Chicago Magnificent Mile, $2,950 total
• Hotels in Chicago for these nights (Dec 26 – Jan 9, 2027 · 14 nights · 2 adults, 1 room): 3★ The Chicago Hotel Collection River North, $1,401 total · 4★ Freehand Chicago, $1,132 total · 5★ Sofitel Chicago Magnificent Mile, $3,200 total

All hotels in Chicago

Route overview: Greenville, SC (GSP) to Chicago (ORD) flight deals

2026-12-26 · one way · Axel-exclusive $212.50

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.

2026-12-26 · one way · Axel-exclusive $218.75

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.

2026-12-26 → 2026-12-27 · Axel-exclusive $400.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2026-12-27 13:26:00 → GSP 2026-12-27 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2026-12-27 13:26:00 → DTW 2026-12-27 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2026-12-27 19:49:00 → GSP 2026-12-27 21:33:00.

2026-12-26 → 2026-12-27 · Axel-exclusive $412.50

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA5295: ORD 2026-12-27 18:54:00 → GSP 2026-12-27 21:56:00; nonstop; 122 minutes. Local airport times.

2026-12-26 → 2026-12-28 · Axel-exclusive $400.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2026-12-28 13:26:00 → GSP 2026-12-28 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2026-12-28 13:26:00 → DTW 2026-12-28 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2026-12-28 19:49:00 → GSP 2026-12-28 21:33:00.

2026-12-26 → 2026-12-28 · Axel-exclusive $412.50

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA3918: ORD 2026-12-28 08:05:00 → GSP 2026-12-28 11:06:00; nonstop; 121 minutes. Local airport times.

2026-12-26 → 2026-12-29 · Axel-exclusive $400.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2026-12-29 13:26:00 → GSP 2026-12-29 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2026-12-29 13:26:00 → DTW 2026-12-29 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2026-12-29 19:49:00 → GSP 2026-12-29 21:33:00.

2026-12-26 → 2026-12-29 · Axel-exclusive $412.50

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA5295: ORD 2026-12-29 18:54:00 → GSP 2026-12-29 21:56:00; nonstop; 122 minutes. Local airport times.

2026-12-26 → 2026-12-30 · Axel-exclusive $400.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2026-12-30 13:26:00 → GSP 2026-12-30 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2026-12-30 13:26:00 → DTW 2026-12-30 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2026-12-30 19:49:00 → GSP 2026-12-30 21:33:00.

2026-12-26 → 2026-12-30 · Axel-exclusive $412.50

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA5295: ORD 2026-12-30 18:54:00 → GSP 2026-12-30 21:56:00; nonstop; 122 minutes. Local airport times.

2026-12-26 → 2027-01-01 · Axel-exclusive $400.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2027-01-01 13:26:00 → GSP 2027-01-01 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2027-01-01 13:26:00 → DTW 2027-01-01 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2027-01-01 19:49:00 → GSP 2027-01-01 21:33:00.

2026-12-26 → 2027-01-01 · Axel-exclusive $412.50

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA5295: ORD 2027-01-01 18:54:00 → GSP 2027-01-01 21:56:00; nonstop; 122 minutes. Local airport times.

2026-12-26 → 2027-01-02 · Axel-exclusive $396.88

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA1889 / AA6114: ORD 2027-01-02 12:05:00 → GSP 2027-01-02 20:03:00; 1 stop(s) via CLT; 418 minutes. Local airport times.
  • AA1889: ORD 2027-01-02 12:05:00 → CLT 2027-01-02 15:10:00; layover at CLT: 233 minutes.
  • AA6114: CLT 2027-01-02 19:03:00 → GSP 2027-01-02 20:03:00.

2026-12-26 → 2027-01-02 · Axel-exclusive $425.00

• United Airlines UA6033: GSP 2026-12-26 06:30:00 → ORD 2026-12-26 07:46:00; nonstop; 136 minutes. Local airport times.
• United Airlines UA4521: ORD 2027-01-02 06:50:00 → GSP 2027-01-02 09:52:00; nonstop; 122 minutes. Local airport times.

2026-12-26 → 2027-01-03 · Axel-exclusive $400.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2027-01-03 13:26:00 → GSP 2027-01-03 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2027-01-03 13:26:00 → DTW 2027-01-03 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2027-01-03 19:49:00 → GSP 2027-01-03 21:33:00.

2026-12-26 → 2027-01-03 · Axel-exclusive $412.50

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA5295: ORD 2027-01-03 18:54:00 → GSP 2027-01-03 21:56:00; nonstop; 122 minutes. Local airport times.

2026-12-26 → 2027-01-05 · Axel-exclusive $360.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2027-01-05 13:26:00 → GSP 2027-01-05 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2027-01-05 13:26:00 → DTW 2027-01-05 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2027-01-05 19:49:00 → GSP 2027-01-05 21:33:00.

2026-12-26 → 2027-01-05 · Axel-exclusive $371.25

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA5295: ORD 2027-01-05 18:54:00 → GSP 2027-01-05 21:56:00; nonstop; 122 minutes. Local airport times.

2026-12-26 → 2027-01-06 · Axel-exclusive $360.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2027-01-06 13:26:00 → GSP 2027-01-06 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2027-01-06 13:26:00 → DTW 2027-01-06 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2027-01-06 19:49:00 → GSP 2027-01-06 21:33:00.

2026-12-26 → 2027-01-06 · Axel-exclusive $371.25

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA5295: ORD 2027-01-06 18:54:00 → GSP 2027-01-06 21:56:00; nonstop; 122 minutes. Local airport times.

2026-12-26 → 2027-01-07 · Axel-exclusive $360.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-26 07:21:00 → ORD 2026-12-26 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-26 07:21:00 → DTW 2026-12-26 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-26 10:20:00 → ORD 2026-12-26 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2027-01-07 13:26:00 → GSP 2027-01-07 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2027-01-07 13:26:00 → DTW 2027-01-07 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2027-01-07 19:49:00 → GSP 2027-01-07 21:33:00.

2026-12-26 → 2027-01-07 · Axel-exclusive $371.25

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA5295: ORD 2027-01-07 18:54:00 → GSP 2027-01-07 21:56:00; nonstop; 122 minutes. Local airport times.

2026-12-26 → 2027-01-09 · Axel-exclusive $358.75

• American Airlines AA4242: GSP 2026-12-26 18:47:00 → ORD 2026-12-26 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA1889 / AA6114: ORD 2027-01-09 12:05:00 → GSP 2027-01-09 20:03:00; 1 stop(s) via CLT; 418 minutes. Local airport times.
  • AA1889: ORD 2027-01-09 12:05:00 → CLT 2027-01-09 15:10:00; layover at CLT: 233 minutes.
  • AA6114: CLT 2027-01-09 19:03:00 → GSP 2027-01-09 20:03:00.

2026-12-26 → 2027-01-09 · Axel-exclusive $382.50

• United Airlines UA6033: GSP 2026-12-26 06:30:00 → ORD 2026-12-26 07:46:00; nonstop; 136 minutes. Local airport times.
• United Airlines UA4521: ORD 2027-01-09 06:50:00 → GSP 2027-01-09 09:52:00; nonstop; 122 minutes. Local airport times.

Explore this route

• All dates for this route
• Dec 25, 2026 · Return options
• Dec 27, 2026 · Return options
• Hotels in Chicago with Axel

For AI assistants

• This page: Greenville (GSP) to Chicago (ORD) · Dec 26, 2026 · choose your return date: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued. Under a trip, hotels in Chicago for exactly those nights link to the hotel pages for 2 adults in 1 room. Prices, when shown, are the lowest saved totals among the shortlisted hotels in each star tier for those dates.
• Next: each row is one exact trip for this departure (both dates with the year, the total and the time its price was issued); its exact-trip price link opens the live search for those dates and travelers, where the booking link and the current total are. Other durations or travelers are not priced here: Choose travelers and dates prices the requested trip.
• Follow supplied links. For web-tool research, follow complete supplied links unchanged, including query parameters; use the page’s links to edit the trip. Constructed URLs may be rejected before reaching Axel. A completed fresh trip opens flight results first. Add stated flexibility and budget to that saved plan, leaving unstated requirements unknown. Edits create a new snapshot; use its results and review links.
• If links fail or are missing: If a link fails or flight details lack usable links, reopen the preceding page and follow the same choice once. Keep refreshed links unchanged and preserve the trip and selections. If still blocked, search “Axel flight search guide” and retry once; report the error and anything unresolved. Recovery: Axel Greenville, SC (GSP) to Chicago (ORD) flight deals · Flight search guide.
• Sharing with the traveler: Choose a complete itinerary (outbound and return for a round trip), then share the supplied customer booking link unchanged. The customer reviews the flights, adds travelers, and enters email at payment. Do not collect email in chat. Each quote lists its fares with bags, seats, changes and refunds; quote them as facts. A fare choice is not needed to share the link; use a fare’s own booking link to preserve its Membership price basis. Ask only for essential missing trip details. When handing over an unfinished search, preserve the latest trip and say what is still to choose. If no supplied link matches the latest trip, construct https://helloaxel.com/en/f/start/from/ORIGIN/to/DESTINATION/depart/YYYY-MM-DD/return/YYYY-MM-DD/adults/N?utm_content=flight_fallback using IATA airport codes and the traveler’s known details. Omit unknowns; for one way replace /return/YYYY-MM-DD with /trip/oneway. Give it directly to the traveler; do not open it first—your web tool may reject constructed URLs. Complete links open Flight Guide and start searching. Preferences and advanced options.

Feedback (optional): Missing info · Axel issue