Greenville (GSP) to Chicago (ORD) · Dec 16, 2026 · return Dec 21, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Greenville, SC (GSP) to Chicago (ORD) flight deals

2026-12-16 → 2026-12-21 · Axel-exclusive $371.25

• American Airlines AA4242: GSP 2026-12-16 18:47:00 → ORD 2026-12-16 20:15:00; nonstop; 148 minutes. Local airport times.
• American Airlines AA3918: ORD 2026-12-21 08:05:00 → GSP 2026-12-21 11:06:00; nonstop; 121 minutes. Local airport times.

2026-12-16 → 2026-12-21 · Axel-exclusive $382.50

• United Airlines UA5862: GSP 2026-12-16 14:04:00 → ORD 2026-12-16 15:15:00; nonstop; 131 minutes. Local airport times.
• United Airlines UA4521: ORD 2026-12-21 06:29:00 → GSP 2026-12-21 09:30:00; nonstop; 121 minutes. Local airport times.

2026-12-16 → 2026-12-21 · Axel-exclusive $360.00

• Delta Air Lines DL1725 / DL2879: GSP 2026-12-16 14:07:00 → ORD 2026-12-16 19:05:00; 1 stop(s) via ATL; 358 minutes. Local airport times.
  • DL1725: GSP 2026-12-16 14:07:00 → ATL 2026-12-16 15:14:00; layover at ATL: 151 minutes.
  • DL2879: ATL 2026-12-16 17:45:00 → ORD 2026-12-16 19:05:00.
• Delta Air Lines DL5187 / DL5285: ORD 2026-12-21 13:26:00 → GSP 2026-12-21 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2026-12-21 13:26:00 → DTW 2026-12-21 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2026-12-21 19:49:00 → GSP 2026-12-21 21:33:00.

2026-12-16 → 2026-12-21 · Axel-exclusive $371.25

• American Airlines AA3731: GSP 2026-12-16 16:54:00 → ORD 2026-12-16 18:10:00; nonstop; 136 minutes. Local airport times.
• American Airlines AA3918: ORD 2026-12-21 08:05:00 → GSP 2026-12-21 11:06:00; nonstop; 121 minutes. Local airport times.

2026-12-16 → 2026-12-21 · Axel-exclusive $382.50

• United Airlines UA6033: GSP 2026-12-16 06:30:00 → ORD 2026-12-16 07:46:00; nonstop; 136 minutes. Local airport times.
• United Airlines UA4521: ORD 2026-12-21 06:29:00 → GSP 2026-12-21 09:30:00; nonstop; 121 minutes. Local airport times.

2026-12-16 → 2026-12-21 · Axel-exclusive $358.75

• American Airlines AA6099 / AA3178: GSP 2026-12-16 13:37:00 → ORD 2026-12-16 17:45:00; 1 stop(s) via CLT; 308 minutes. Local airport times.
  • AA6099: GSP 2026-12-16 13:37:00 → CLT 2026-12-16 14:49:00; layover at CLT: 100 minutes.
  • AA3178: CLT 2026-12-16 16:29:00 → ORD 2026-12-16 17:45:00.
• American Airlines AA3918: ORD 2026-12-21 08:05:00 → GSP 2026-12-21 11:06:00; nonstop; 121 minutes. Local airport times.

2026-12-16 → 2026-12-21 · Axel-exclusive $358.75

• American Airlines AA5083 / AA3183: GSP 2026-12-16 15:41:00 → ORD 2026-12-16 21:31:00; 1 stop(s) via DCA; 410 minutes. Local airport times.
  • AA5083: GSP 2026-12-16 15:41:00 → DCA 2026-12-16 17:27:00; layover at DCA: 159 minutes.
  • AA3183: DCA 2026-12-16 20:06:00 → ORD 2026-12-16 21:31:00.
• American Airlines AA3918: ORD 2026-12-21 08:05:00 → GSP 2026-12-21 11:06:00; nonstop; 121 minutes. Local airport times.

2026-12-16 → 2026-12-21 · Axel-exclusive $360.00

• Delta Air Lines DL5215 / DL3902: GSP 2026-12-16 07:21:00 → ORD 2026-12-16 10:59:00; 1 stop(s) via DTW; 278 minutes. Local airport times.
  • DL5215: GSP 2026-12-16 07:21:00 → DTW 2026-12-16 09:12:00; layover at DTW: 68 minutes.
  • DL3902: DTW 2026-12-16 10:20:00 → ORD 2026-12-16 10:59:00.
• Delta Air Lines DL5187 / DL5285: ORD 2026-12-21 13:26:00 → GSP 2026-12-21 21:33:00; 1 stop(s) via DTW; 427 minutes. Local airport times.
  • DL5187: ORD 2026-12-21 13:26:00 → DTW 2026-12-21 15:54:00; layover at DTW: 235 minutes.
  • DL5285: DTW 2026-12-21 19:49:00 → GSP 2026-12-21 21:33:00.

2026-12-16 → 2026-12-21 · Axel-exclusive $367.50

• United Airlines UA4521 / UA1786: GSP 2026-12-16 10:26:00 → ORD 2026-12-16 16:54:00; 1 stop(s) via IAD; 448 minutes. Local airport times.
  • UA4521: GSP 2026-12-16 10:26:00 → IAD 2026-12-16 11:55:00; layover at IAD: 215 minutes.
  • UA1786: IAD 2026-12-16 15:30:00 → ORD 2026-12-16 16:54:00.
• United Airlines UA4521: ORD 2026-12-21 06:29:00 → GSP 2026-12-21 09:30:00; nonstop; 121 minutes. Local airport times.

Explore this route

• All dates for this route
• Dec 15, 2026 · Return options
• Dec 17, 2026 · Return options
• Hotels in Chicago with Axel

For AI assistants

• This page: Greenville (GSP) to Chicago (ORD) · Dec 16, 2026 · return Dec 21, 2026: 1 adult in economy, every priced fare with its flights, times and total, each with the time its price was issued.
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