Detroit (DTW) to Knoxville (TYS) · Nov 27, 2026 · return Nov 29, 2026

Flights for 1 adult in economy. Prices are total for all travelers in USD, including required taxes. Basic economy may apply.

See flights for these dates: each price link opens AI flight search for that row's exact dates and travelers. Select the complete itinerary there.

Route overview: Detroit to Knoxville (TYS) flight deals

2026-11-27 → 2026-11-29 · Axel-exclusive $448.50

• Delta Air Lines DL5138: DTW 2026-11-27 19:58:00 → TYS 2026-11-27 21:33:00; nonstop; 95 minutes. Local airport times.
• Delta Air Lines DL4697: TYS 2026-11-29 17:10:00 → DTW 2026-11-29 18:57:00; nonstop; 107 minutes. Local airport times.

2026-11-27 → 2026-11-29 · Axel-exclusive $370.50

• Southwest Airlines WN4679 / WN1875: DTW 2026-11-27 06:00:00 → TYS 2026-11-27 12:20:00; 1 stop(s) via BNA; 380 minutes. Local airport times.
  • WN4679: DTW 2026-11-27 06:00:00 → BNA 2026-11-27 06:55:00; layover at BNA: 205 minutes.
  • WN1875: BNA 2026-11-27 10:20:00 → TYS 2026-11-27 12:20:00.
• Southwest Airlines WN463 / WN1991: TYS 2026-11-29 17:15:00 → DTW 2026-11-29 21:25:00; 1 stop(s) via BNA; 250 minutes. Local airport times.
  • WN463: TYS 2026-11-29 17:15:00 → BNA 2026-11-29 17:15:00; layover at BNA: 80 minutes.
  • WN1991: BNA 2026-11-29 18:35:00 → DTW 2026-11-29 21:25:00.

2026-11-27 → 2026-11-29 · Axel-exclusive $383.50

• American Airlines AA3364 / AA3661: DTW 2026-11-27 13:40:00 → TYS 2026-11-27 18:46:00; 1 stop(s) via ORD; 306 minutes. Local airport times.
  • AA3364: DTW 2026-11-27 13:40:00 → ORD 2026-11-27 14:17:00; layover at ORD: 103 minutes.
  • AA3661: ORD 2026-11-27 16:00:00 → TYS 2026-11-27 18:46:00.
• American Airlines AA5118 / AA2376: TYS 2026-11-29 08:50:00 → DTW 2026-11-29 15:43:00; 1 stop(s) via CLT; 413 minutes. Local airport times.
  • AA5118: TYS 2026-11-29 08:50:00 → CLT 2026-11-29 10:17:00; layover at CLT: 218 minutes.
  • AA2376: CLT 2026-11-29 13:55:00 → DTW 2026-11-29 15:43:00.

2026-11-27 → 2026-11-29 · Axel-exclusive $409.50

• United Airlines UA6362 / UA4304: DTW 2026-11-27 19:45:00 → TYS 2026-11-28 00:15:00; 1 stop(s) via IAD; 270 minutes. Local airport times.
  • UA6362: DTW 2026-11-27 19:45:00 → IAD 2026-11-27 21:19:00; layover at IAD: 62 minutes.
  • UA4304: IAD 2026-11-27 22:21:00 → TYS 2026-11-28 00:15:00.
• United Airlines UA4848 / UA6246: TYS 2026-11-29 14:07:00 → DTW 2026-11-29 19:09:00; 1 stop(s) via IAD; 302 minutes. Local airport times.
  • UA4848: TYS 2026-11-29 14:07:00 → IAD 2026-11-29 15:50:00; layover at IAD: 95 minutes.
  • UA6246: IAD 2026-11-29 17:25:00 → DTW 2026-11-29 19:09:00.

2026-11-27 → 2026-11-29 · Axel-exclusive $448.50

• Delta Air Lines DL4989: DTW 2026-11-27 16:10:00 → TYS 2026-11-27 17:49:00; nonstop; 99 minutes. Local airport times.
• Delta Air Lines DL4697: TYS 2026-11-29 17:10:00 → DTW 2026-11-29 18:57:00; nonstop; 107 minutes. Local airport times.

2026-11-27 → 2026-11-29 · Axel-exclusive $370.50

• Southwest Airlines WN2069 / WN3687: DTW 2026-11-27 15:55:00 → TYS 2026-11-27 20:50:00; 1 stop(s) via BWI; 295 minutes. Local airport times.
  • WN2069: DTW 2026-11-27 15:55:00 → BWI 2026-11-27 17:25:00; layover at BWI: 100 minutes.
  • WN3687: BWI 2026-11-27 19:05:00 → TYS 2026-11-27 20:50:00.
• Southwest Airlines WN463 / WN1991: TYS 2026-11-29 17:15:00 → DTW 2026-11-29 21:25:00; 1 stop(s) via BNA; 250 minutes. Local airport times.
  • WN463: TYS 2026-11-29 17:15:00 → BNA 2026-11-29 17:15:00; layover at BNA: 80 minutes.
  • WN1991: BNA 2026-11-29 18:35:00 → DTW 2026-11-29 21:25:00.

2026-11-27 → 2026-11-29 · Axel-exclusive $383.50

• American Airlines AA3311 / AA5292: DTW 2026-11-27 16:50:00 → TYS 2026-11-27 21:57:00; 1 stop(s) via CLT; 307 minutes. Local airport times.
  • AA3311: DTW 2026-11-27 16:50:00 → CLT 2026-11-27 18:45:00; layover at CLT: 115 minutes.
  • AA5292: CLT 2026-11-27 20:40:00 → TYS 2026-11-27 21:57:00.
• American Airlines AA5118 / AA2376: TYS 2026-11-29 08:50:00 → DTW 2026-11-29 15:43:00; 1 stop(s) via CLT; 413 minutes. Local airport times.
  • AA5118: TYS 2026-11-29 08:50:00 → CLT 2026-11-29 10:17:00; layover at CLT: 218 minutes.
  • AA2376: CLT 2026-11-29 13:55:00 → DTW 2026-11-29 15:43:00.

2026-11-27 → 2026-11-29 · Axel-exclusive $422.50

• Delta Air Lines DL1467 / DL5272: DTW 2026-11-27 15:59:00 → TYS 2026-11-27 21:56:00; 1 stop(s) via ATL; 357 minutes. Local airport times.
  • DL1467: DTW 2026-11-27 15:59:00 → ATL 2026-11-27 18:03:00; layover at ATL: 169 minutes.
  • DL5272: ATL 2026-11-27 20:52:00 → TYS 2026-11-27 21:56:00.
• Delta Air Lines DL4697: TYS 2026-11-29 17:10:00 → DTW 2026-11-29 18:57:00; nonstop; 107 minutes. Local airport times.

Travelers: prices on this page are totals for 1 adult. For a different party, open this trip for 2 adults · 3 adults · 4 adults · 2 adults + 1 child · 2 adults + 2 children; each link opens AI flight search for these dates and those travelers, and the customer link to share comes from those results.

Explore this route

• All dates for this route
• Nov 26, 2026 · Return options
• Nov 28, 2026 · Return options
• Hotels in Knoxville with Axel

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